الصفحة 15
الصفحة 15
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Matrix Metalloproteinases in Tissue Remodelling and Inflammation

Matrix metalloproteinases (MMPs) are proteolytic enzymes believed to be involved in many physiological and pathological processes associated with inflammatory reactions. This volume presents new advances in the involvement of MMPs in various diseases associated with inflammatory processes. Moreover, the recent development of selective and non selective inhibitors of MMPs provides new insights in the relationship between activation of inflammatory cells and tissue remodelling and advises new therapeutic possibilities for the treatment of inflammatory diseases.

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Mathematical Morphology : 40 Years On ; Proceedings of the 7th International Symposium on Mathematical Morphology, April 18-20, 2005

Mathematical Morphology is a speciality in Image Processing and Analysis, which considers images as geometrical objects, to be analyzed through their interactions with other geometrical objects. It relies on several branches of mathematics, such as discrete geometry, topology, lattice theory, partial differential equations, integral geometry and geometrical probability. It has produced fast and efficient algorithms for computer analysis of images, and has found applications in bio-medical imaging, materials science, geoscience, remote sensing, quality control, document processing and data analysis. This book contains the 43 papers presented at the 7th International Symposium on Mathematical Morphology, held in Paris on April 18-20, 2005. It gives a lively state of the art of current research topics in this field. It also marks a milestone, the 40 years of uninterrupted development of this ever-expanding domain.

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Islamic Bioethics : Problems and Perspectives

This book presents a critical analysis of the debate at the religious, legal and political level sparked off by the introduction of new biomedical technologies (cloning, genetics, organ transplants, IVF, etc.) in Muslim countries. It compares the positions of "classic" Muslim law and contemporary religious authorities; laws in Muslim countries; the attitudes and concrete behaviour of populations, families and individuals, as well as the regulations of medical associations, bioethics committees etc..

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Iron Nutrition in Plants and Rhizospheric Microorganisms

This book uses an interdisciplinary approach to provide a comprehensive review on the status of iron nutrition in plants. International scientists discuss research on acquisition of iron by strategy I and strategy II plants. These reviews summarize a variety of plant species and include both laboratory and field observations. Topics covered in this book include: plants as a source of iron for animals and humans, iron translocation in the plants, iron-stimulated activities that influence crop yield and fruit tree productivity, iron uptake by plants as influenced by microorganisms (i.e. free living soil microorganisms, symbiotic nitrogen-fixing and pathogenic bacteria), the role of plant hormones in iron transport, iron-metal competition in phytoremediation, root zone activities involving interactions between minerals and organic matter, the role of microbial siderophores in rhizospheric iron cycling, iron storage as phytoferritin, proteomic and metabolic studies associated with iron stress response, methods for studying iron metabolism including stable isotopes, and the correction of iron deficiency through the use of synthetic or natural chelates.

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Iron metabolism : Methods and protocols

Explores classical and cutting-edge methods optimized and validated to analyze various aspects of iron metabolism, from in vitro to multi-organ level. Opening with a section on basic iron metabolism methods, the book continues with methods applicable to a variety of systems, ranging from bacteria to cultured mammalian cells and tissues, with a focus on cellular heme and iron-sulfur cluster species, as well as mitochondrial iron and its derivatives. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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IoT-enabled Smart Healthcare Systems, Services and Applications

In IoT-Enabled Smart Healthcare Systems, Services and Applications, an accomplished team of researchers delivers an insightful and comprehensive exploration of the roles played by cutting-edge technologies in modern healthcare delivery. The distinguished editors have included resources from a diverse array of learned experts in the field that combine to create a broad examination of a rapidly developing field.

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Inverse Problems and Imaging : Lectures given at the C.I.M.E. Summer School held in Martina Franca, Italy September 15–21, 2002

Nowadays we are facing numerous and important imaging problems: nondestructive testing of materials, monitoring of industrial processes, enhancement of oil production by efficient reservoir characterization, emerging developments in noninvasive imaging techniques for medical purposes - computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), X-ray and ultrasound tomography, etc. In the CIME Summer School on Imaging (Martina Franca, Italy 2002), leading experts in mathematical techniques and applications presented broad and useful introductions for non-experts and practitioners alike to many aspects of this exciting field. The volume contains part of the above lectures completed and updated by additional contributions on other related topics: a general presentation and introduction (Moscoso), X-ray tomography (Natterer), Electromagnetic imaging (Dorn, Bertete-Aguirre, Papanicolaou), coherent imaging in telecommunications in a multiple input-multiple output setup (Dorn), polarization based optical imaging (Moscoso), topological derivatives used in shape reconstruction related to inverse scattering problems (Carpio, Rapún), Point interactions (Dell’Antonio, Figari, Teta).

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Invasive Species in Forests and Rangelands of the United States : A Comprehensive Science Synthesis for the United States Forest Sector

This book describes the serious threat of invasive species to native ecosystems. Invasive species have caused and will continue to cause enormous ecological and economic damage with ever increasing world trade.

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Invasive Plants : Ecological and Agricultural Aspects

The study of plant invasions is the science that attempts to understand causes and consequences of plant introductions outside of their native areas. contributing authors have strived to provide up-to-date reviews and discussions of invasion-related research involving natural and agroecosystems. Readers will get a unique perspective on ecological and agricultural aspects of plant invasions through employing general principles of ecology to plant invasions.

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Invasive forest insects, introduced forest trees, and altered ecosystems : Ecological pest management in global forests of a changing world

Demand for timber and fibre continues to grow and is being met by increased reliance on plantation forestry. Many of the plantations that are being grown around the globe are non-native species that have characteristics of rapid growth and good commercial qualities. In some cases, the high rates of production are a result of the absence of native herbivore and diseases. This limited pest status is threatened as pest species move around the globe. At the same time there is concern about threats of these non-native plantation species on native communities and the impact of changing climates on forest productivity. This volume explores many of these issues for the first time.

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Introduzione alla medicina molecolare = Introduction to molecular medicine

An indispensable guide for understanding a young science with rapid and promising developments. Now in its third completely revised edition, it presents in a concise yet comprehensive way the scientific and technological principles of this discipline and provides, in widely accessible language, the basic conceptual tools for understanding the human genome, gene expression and regulation, the various aspects of genetic engineering that allow for the manipulation of DNA, and human cloning.

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Introduction to Systems Biology

Informative and cutting-edge, this volume presents a clear and intuitive illustration of the biological systemic approaches and introduces ideal computational methods for research. Introduction to Systems Biology is an indispensable resource, providing a first glimpse into the state-of-the-art in systems biology.

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Introduction to organic and medicinal chemistry

Designed to be an undergraduate reference textbook for students of chemistry who aim to select degree modules geared towards medicinal chemistry. The first two chapters offer an overview of basic organic chemistry, followed by organic synthesis in Chapter 3, with an emphasis on the importance of synthetic procedures in relation to the chemistry of drug design. In Chapter 4, the book covers foundational aspects of biochemistry and biomedical science to provide a basis for students understanding where and how drugs work on selected targets. Later, the book explains how medicines have been created for selected topics in medicinal chemistry – namely against pathogens, cancer and neurological targets.

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Introduction to Mathematical Methods in Bioinformatics

This book looks at the mathematical foundations of the models currently in use. This book is unique in the sense that it looks at the mathematical foundations of the models, which are crucial for correct interpretation of the outputs of the models.

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Introduction to Epigenetics

This textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants.

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Introduction to Computational Biology : An Evolutionary Approach

Molecular biology has changed dramatically over the past two decades. Until the early 1990s genes were studied one at a time by small teams of researchers; today entire genomes are sequenced by internationally collaborating laboratories. In the bygone gene-centered era the accumulation of data was the rate-limiting step in research. Now that step is often data interpretation. This is increasingly dependent on computational methods and as a consequence, computational biology has emerged in the past decade as a new subdiscipline of biology. This introduction to computational biology is centered on the analysis of molecular sequence data. There are two closely connected aspects to biological sequences: (i) their relative position in the space of all other sequences, and (ii) their movement through this sequence space in evolutionary time. Accordingly, the first part of the book deals with classical methods of sequence analysis: pairwise alignment, exact string matching, multiple alignment, and hidden Markov models. In the second part evolutionary time takes center stage and phylogenetic reconstruction, the analysis of sequence variation, and the dynamics of genes in populations are explained in detail. In addition, the book contains a computer program with a graphical user interface that allows the reader to experiment with a number of key concepts developed by the authors.

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Introduction to Biosemiotics : The New Biological Synthesis

This book is addressed to students, researchers and academics who have barely heard of the emerging young science of Biosemiotics, and who want to know more about it. Written by many of the field’s major contributors, it provides a highly qualified introduction to Biosemiotics and illustrates the most recent views in its background and development.

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Introduction to basics of pharmacology and toxicology ; Vol.3 : Experimental pharmacology : Research methodology and biostatistics

Elaborates on the general principles of experimental pharmacology. Describes about the screening methods for the evaluation of different categories of drugs. Summarizes the various aspects of research methodology and biostatistics.

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Introduction to basics of pharmacology and toxicology ; Vol.2 : Essentials of systemic pharmacology : From principles to practice

Describes the pharmacology of drugs acting on different systems in the human body Analyses various human diseases and the pharmacological agents governing them Provides a valuable reference resource for academicians, researchers, and clinical practitioners Offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics.

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Introduction to basics of pharmacology and toxicology ; Vol.1 : General and molecular pharmacology : Principles of drug action

Illustrates the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases.

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