الصفحة 15
الصفحة 15
Malaria disease and modern treatments
Some population groups are at considerably higher risk of contracting malaria and developing severe disease: infants, children under 5 years of age, pregnant women and patients with HIV/AIDS, as well as people with low immunity moving to areas with intense malaria transmission such as migrant workers, mobile populations and travellers. Malaria is an acute febrile illness caused by Plasmodium parasites, which are spread to people through the bites of infected female Anopheles mosquitoes. There are 5 parasite species that cause malaria in humans, and 2 of these species – P. falciparum and P. vivax – pose the greatest threat. P. falciparum is the deadliest malaria parasite and the most prevalent on the African continent. P. vivax is the dominant malaria parasite in most countries outside of sub-Saharan Africa.
Making Grids Work ; Proceedings of the CoreGRID Workshop on Programming Models Grid and P2P System Architecture Grid Systems, Tools and Environments 12-13 June 2007, Heraklion, Crete, Greece
Making Grids Work includes selected articles from the CoreGRID Workshop on Grid Programming Models, Grid and P2P Systems Architecture, Grid Systems, Tools and Environments held at the Institute of Computer Science, Foundation for Research and Technology - Hellas in Crete, Greece, June 2007. This workshop brought together representatives of the academic and industrial communities performing Grid research in Europe. Organized within the context of the CoreGRID Network of Excellence, this workshop provided a forum for the presentation and exchange of views on the latest developments in Grid Technology research. This volume is the 7th in the series of CoreGRID books.
Magnetohydrodynamics : Historical Evolution and Trends
Magnetohydrodynamics (MHD) studies the interaction between the flow of an electrically conducting fluid and magnetic fields. It involves such diverse topics as the evolution and dynamics of astrophysical objects, thermonuclear fusion, metallurgy and semiconductor crystal growth, etc. Although the first ideas in magnetohydrodynamics appeared at the beginning of the last century, the "explosion" in theoretical and experimental studies occurred in the 1950s-60s. This state-of-the-art book aims at revising the evolution of ideas in various branches of magnetohydrodynamics (astrophysics, earth and solar dynamos, plasmas, MHD turbulence and liquid metals) and reviews current trends and challenges.
Magnetic Control of Tokamak Plasmas
The main topic of Magnetic Control of Tokamak Plasmas is the design of feedback control systems guaranteeing the stability of plasma equilibrium inside a tokamak and the regulation of the plasma position and shape during plasma pulses. Modelling and control details are presented, allowing the non-expert to understand the control problem. Starting from equations of magneto-hydro-dynamics, all the steps needed for the derivation of plasma state-space models are enumerated. The basics of electromagnetics are frequently recalled. The control problem is then described beginning with control of current and position – vertical and radial – and progressing to the more challenging shape control. The solutions proposed vary from simple PIDs to more sophisticated MIMO controllers.
Macroscopic Transport Equations for Rarefied Gas Flows : Approximation Methods in Kinetic Theory
This book discusses classical and modern methods to derive macroscopic transport equations for rarefied gases from the Boltzmann equation, for small and moderate Knudsen numbers, i.e.as well as the new order of magnitude method, which avoids the short-comings of the classical methods, but retains their benefits.
Lymphocyte Signal Transduction
Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational modifications, lead to the activation of transcription factors that mediate cellular differentiation and growth, effector cell functions, and apoptotic cell death. Several investigators from various parts of the world convened at the 3rd Lymphocyte Signal Transduction Workshop in Crete, Greece from May 27 to June 1, 2005 to discuss their most recent findings in leukocyte signaling. This volume represents a collection of topics discussed during the conference.
Low-Temperature Physics
This book provides a concise but thorough introduction to important phenomena of low-temperature physics. It is ideally suited as a textbook for advanced undergraduates but will also be valuable for graduate students, scientists and engineers working in this field. Clear explanations of both theoretical and experimental approaches coupled with carefully selected problems will enable students to gain a firm understanding of even the most recent research developments.
Loop Spaces, Characteristic Classes and Geometric Quantization
This book deals with the differential geometry of manifolds, loop spaces, line bundles and groupoids, and the relations of this geometry to mathematical physics. Various developments in mathematical physics (e.g., in knot theory, gauge theory, and topological quantum field theory) have led mathematicians and physicists to search for new geometric structures on manifolds and to seek a synthesis of ideas from geometry, topology and category theory. In this spirit, this book develops the differential geometry associated to the topology and obstruction theory of certain fiber bundles (more precisely, associated to grebes). The theory is a 3-dimensional analog of the familiar Kostant--Weil theory of line bundles. In particular the curvature now becomes a 3-form.
Lippincott illustrated reviews : Pharmacology
Presents up-to-date drug information in an accessible format ideal for a fast, effective refresher. Part of the popular Lippincott® Illustrated Reviews series, this concise resource features clear, effective writing and hundreds of illustrations that break down complex information for rapid review. Sequential images present mechanisms of action and focus on showing rather than telling students how drugs work, and review questions with answers deliver powerful, practical exam preparation. Updated drug information reflects the most current, clinically relevant pharmacology material. Approachable outline format distills complex information for easier review. High-quality illustrations reinforce understanding in vibrant detail. Enhanced review questions with answers test students' understanding and identify areas for further study.
Lipids in Health and Disease
Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
Linear Algebraic Monoids
The theory of linear algebraic monoids culminates in a coherent blend of algebraic groups, convex geometry, and semigroup theory. The book discusses all the key topics in detail, including classification, orbit structure, representations, universal constructions, and abstract analogues. An explicit cell decomposition is constructed for the wonderful compactification, as is a universal deformation for any semisimple group. A final chapter summarizes important connections with other areas of algebra and geometry. The book will serve as a solid basis for further research. Open problems are discussed as they arise and many useful exercises are included.
Light Scattering in Solids IX : Novel Materials and Techniques
Reviews recent developments concerning mainly semiconductor nanostructures and inelastic x-ray scattering, including both coherent time-domain and spontaneous scattering studies.
Life - As a Matter of Fat : The Emerging Science of Lipidomics
Lipids are as important for life as proteins, sugars, and genes. The present book gives a multi-disciplinary perspective on the physics of life and the particular role played by lipids and the lipid-bilayer component of cell membranes. The book is aimed at undergraduate students and young research workers within physics, chemistry, biochemistry, molecular biology, nutrition, as well as pharmaceutical and biomedical sciences. The emphasis is on the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Furthermore, it is shown how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nano-technology and biomedicine are also described.
Lattice Boltzmann Modeling : An Introduction for Geoscientists and Engineers
Lattice Boltzmann models have a remarkable ability to simulate single- and multi-phase fluids and transport processes within them. A rich variety of behaviors, including higher Reynolds numbers flows, phase separation, evaporation, condensation, cavitation, buoyancy, and interactions with surfaces can readily be simulated. This book provides a basic introduction that emphasizes intuition and simplistic conceptualization of processes. It avoids the more difficult mathematics that underlies LB models. The model is viewed from a particle perspective where collisions, streaming, and particle-particle/particle-surface interactions constitute the entire conceptual framework. Beginners and those with more interest in model application than detailed mathematical foundations will find this a powerful "quick start" guide. Example simulations, exercises, and computer codes are included. Working code is provided on the Internet
L'astrofilo moderno = The modern amateur astronomer
In less than two decades, amateur astronomy has changed its face. The reason, of course, is technological progress. Cheap but high-quality telescopes, computer-controlled "go-to" mounts, autoguiders, CCD cameras, video cameras and (as always) computers and the Internet are just some of the elements that revolutionized 21st century astronomy. Not only have they made amateur astronomy more "friendly" and fun, but they have also greatly expanded the potential of the amateur astronomer. Martin Mobberley first tackles the basic issues and then analyzes in depth what tools are available on the market. From here he starts to review the revolutionary possibilities that open up for amateur astronomers, from imaging, to spectroscopy, to photometry, to the surveillance of Near-Earth objects - comets and asteroids that can come dangerously close to the Earth.
Large Eddy Simulation for Incompressible Flows : An Introduction
First concise textbook on Large-Eddy Simulation, a very important method in scientific computing and engineeringFrom the foreword to the third edition written by Charles Meneveau: ".
Landscapes of Lifelong Learning Policies across Europe : Comparative Case Studies
This book explores different landscapes of Lifelong Learning policies (LLP), producing case-based examinations of their institutional, discursive, and relational dimensions. Across Europe, young people develop their life courses amidst diverse living conditions and are confronted with a variety of institutional and structural arrangements that impact on their opportunities in education and labour. Considering the relevance of LLP in shaping those opportunities, the chapters draw from multi-level, mixed-methods research and offer original insights on the interplay of discourses and governance patterns in the processes of policy-making and deliverance. The book yields noteworthy insights into the widely differing realities across the European landscape, and also into the diverging ways young people deal with and actively participate in LLP.
Lake Victoria : Ecology, Resources, Environment
Recently, there has been, and continues to be, a tremendous interest on Lake Victoria and its environs, both locally and internationally. A casual browsing on the Internet indicates that the entries on the Lake have been rising phenomenally. At the same time, the issues discussed are as diverse as they are varied in their treatment of the subject, both in terms of depth and comprehensiveness. The information on Lake Victoria and its environ is scattered, isolated, and sometimes confusing even though documentation on the subject are available. Despite this situation, the fact remains that various people (e. g. , secondary and universitystudents,researchers,practitioners,etc. ,)wouldliketoaccess and know more about the Lake and its environs. Aware of the existing information gap about this world’s second largest fresh water Lake, this book is intended to provide readers with up-to-date information pertaining the Lake. The book gives an in-depth coverage of environmental issues, - source endowment, poverty amidst plenty, development opportunities, challenges and other related issues facing the Lake and its environs. It aims at providing information on the above variables, which hopefully will address the needs of various users.
La scuola dell’atopia = The school of atopy
The need to clarify the current concepts of atopy, which for too long have oscillated between a primitive purely clinical vision and a subsequent purely immunological one, had been ripe for some time. Understanding that the role of immunoglobulins E is not exhaustive and accepting the Solomonic division between intrinsic and extrinsic atopy were the first two fundamental steps. Recent discoveries of the role of innate immunity, and therefore of antimicrobial peptides, have opened fundamental spaces for understanding in atopy and beyond. What now appears clear is that atopy is not the disease of an organ but rather a defect in the membranes that delimit our "self". The fact that these membranes are called skin, intestines, conjunctiva, bronchi or whatever has artificially fragmented the understanding and treatment of a unitary phenomenon. This book seeks to summarize the different experiences but above all to be a stimulus to ensure that medicine focuses constructively on the same target. If this is the case, we will no longer see "religious wars" between scientists and practicing doctors or, even worse, between the different specialists vying for the patient. If atopy, as we believe, is a global problem, it can only be adequately addressed in a multidisciplinary context and in a collaborative atmosphere, not only between doctor and doctor but also between doctor and patient.
La protesi di ginocchio di primo impianto = The first-time knee prosthesis
Total knee replacement has now become a routine procedure in our operating rooms. The widespread use of this procedure, however, should not obscure the complexity of this joint surgery, which also relies on sophisticated computer aids. Drawing on their long and proven experience, the authors of this fourth volume in the series provide the reader with an updated overview of the state of the art.
