الصفحة 15
الصفحة 15
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Molecular biology : Structure and dynamics of genomes and proteomes

Illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA, RNA, and proteins. Emphasis is on the experimental basis of discovery and the most recent advances in the field while presenting a rigorous, yet still concise, summary of the structural mechanisms of molecular biology. Topics new to this edition include the CRISPR-Cas gene editing system, Coronaviruses – structure, genome, vaccine and drug development, and newly recognized mechanisms for transcription termination.

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Molecular and Cellular Signaling

A small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determine what kinds of cells are made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders to cancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer. Molecular and Cellular Signaling provides an introduction to molecular and cellular signaling in biological systems with an emphasis on the underlying physical principles. The text is aimed at upper-level undergraduates, graduate students and individuals in medicine and pharmacology interested in broadening their understanding of how cells regulate and coordinate their core activities and how diseases arise when these regulatory systems malfunction, as well as those in chemistry, physics and computer science interested in pursuing careers in biological and medical physics, bioinformatics and systems biology. To that end, the book includes background information and review sections, and chapters on signaling in the immune, endocrine (hormonal) and nervous systems. It has chapters on cancer, apoptosis and gene regulation, and contains chapters on bacteria and viruses. In those chapters not specifically devoted to pathogens, connections between diseases, drugs and signaling are made. Each chapter also features a problem set to facilitate further discussion and understanding.

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Molecular analyses : Medical genomics and proteomics

Methods for extraction, manipulation, and characterization of nucleic acids, peptides, and proteins have been rapidly developed. Extraction from a variety of tissues and samples have become routine and automated. Next generation sequencing (NGS) methods have been developed. This book focuses on medically-focused methods

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Molar Incisor Hypomineralization : A Clinical Guide to Diagnosis and Treatment

This book is a wide-ranging reference on current clinical and scientific knowledge regarding the various aspects of molar incisor hypomineralization (MIH). Background information is first presented on the structural properties of hypomineralized enamel, the prevalence of MIH, and potential etiological factors.

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Modified Fibers with Medical and Specialty Applications

This book will be an invaluable resource for researchers and others interested in future developments in fiber technology. Several innovative applications for natural and synthetic fibers are described in considerable detail with emphasis on the experimental data that supports these new applications. From bandages to magnetic materials and from antibacterial clothing to implants, creative modifications to fibers are described that could one day become commonplace. Never before has this much new information about fiber modification been packaged into one book volume. In this book the world’s leading experts describe their most recent research in their areas of expertise.

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Modernizing the academic teaching and research environment : Methodologies and cases in business research

Constitutes a valuable manual for young and seasoned business researchers alike, and provides a comprehensive summary for the whole research journey. It is a must-read for all researchers who need to understand the basics of business research, from identifying research topics, to planning and organizing the research process, and selecting the most appropriate methodology for the topic at hand. This book also provides insights on how to avoid common pitfalls in business research and outlines the research skills needed to write a fine piece of research. In order to capture the innovative element of research, the book also highlights methods for thinking outside the box. It also stresses the importance of respecting ethics while conducting business research. Lastly, it presents important cases and provides hands-on training for preparing survey tools. Readers looking to master business research won’t want to miss out on this unique and insightful book.

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Modernisation, Mechanisation and Industrialisation of Concrete Structures

Modernisation, Mechanisation and Industrialisation of Concrete Structures discusses the manufacture of high quality prefabricated concrete construction components, and how that can be achieved through the application of developments in concrete technology, information modelling and best practice in design and manufacturing techniques.

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Modern structural analysis : Modelling process and guidance

Essential reading for 21st century practitioners and students who need to do structural analysis. It contains a great deal of information that is not available in any other book on the subject. This is because the conventional view of structural analysis is rooted in the early part of the 20th century in the pre-computer era rather than present time.

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Modern socio-technical perspectives on privacy

This book provides researchers and professionals with a foundational understanding of online privacy as well as insight into the socio-technical privacy issues that are most pertinent to modern information systems, covering several modern topics (e.g., privacy in social media, IoT) and underexplored areas (e.g., privacy accessibility, privacy for vulnerable populations, cross-cultural privacy).

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Modern operating system

incorporates the latest developments and technologies in operating systems (OS) technologies. Author Andy Tanenbaum's clear and entertaining writing style outlines the concepts every OS designer needs to master. In-depth topic coverage includes processes, threads, memory management, file systems, I/O, deadlocks, interface design, multimedia, performance tradeoffs, and trends in OS design. Case studies explore popular OS and provide real-world context. Tanenbaum also provides information on current research based on his expe

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Modern Multivariate Statistical Techniques : Regression, Classification, and Manifold Learning

Remarkable advances in computation and data storage and the ready availability of huge data sets have been the keys to the growth of the new disciplines of data mining and machine learning, while the enormous success of the Human Genome Project has opened up the field of bioinformatics. These exciting developments, which led to the introduction of many innovative statistical tools for high-dimensional data analysis, are described here in detail. The author takes a broad perspective; for the first time in a book on multivariate analysis, nonlinear methods are discussed in detail as well as linear methods.

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Modern Morphometrics in Physical Anthropology

Morphometrics has undergone a revolutionary transformation in the past two decades as new methods have been developed to address shortcomings in the traditional multivirate analysis of linear distances, angles, and indices. While there is much active research in the field, the new approaches to shape analysis are already making significant and ever-increasing contributions to biological research, including physical anthropology. Modern Morphometrics in Physical Anthropology highlights the basic machinery of the most important methods, while introducing novel extensions to these methods and illustrating how they provide enhanced results compared to more traditional approaches. Modern Morphometrics in Physical Anthropology provides a comprehensive sampling of the applications of modern, sophisticated methods of shape analysis in anthropology, and serves as a starting point for the exploration of these practices by students and researchers who might otherwise lack the local expertise or training to get started. This text is an important resource for the general morphometric community that includes ecologists, evolutionary biologists, systematists, and medical researchers.

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Modern medicines from plants : Botanical histories of some of modern medicine’s most important drugs

Features information on plants from which we obtain modern prescription medicines. It outlines their historical uses as herbal medicines in the past two millennia, using primary sources, and describes how extracts from them, and their semisynthetic and synthetic derivatives, were developed to be today’s therapeutic drugs and diagnostic chemicals. This book describes medicinal plants and their habitats, the diseases that their medicines treat, and the science of how they work.

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Modern medicine : biomedical devices, medical gases, radiopharmaceuticals, new drug discovery, Vol.2

Discusses the procedures of drug approval and regulatory requirements that must be met according to the United States Food and Drug Administration (FDA), the European Medical Agency (EMA), and the Central Drug Standard Control Organization (CDSCO). In the rapidly evolving landscape of modern medicine, groundbreaking innovations have emerged that are reshaping the way we approach healthcare. Modern Medicine delves into the cutting-edge realms of medical devices, medical gases, radiopharmaceuticals, and new drug discovery, offering a comprehensive exploration of these transformative fields that are revolutionizing patient care and medical practices.

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Modern Magnetic Resonance ; Part 1 : Applications in Chemistry, Biological and Marine Sciences ; Part 2 : Applications in Medical and Pharmaceutical Sciences ; Part 3 : Applications in Materials Science and Food Science

Modern Magnetic Resonance provides a unique and comprehensive resource on up-to-date uses and applications of magnetic resonance techniques in the sciences, including chemistry, biology, materials, food, medicine, pharmaceuticals and marine sciences.The widespread appeal of MMR methods for revealing information at the molecular and microscopic levels is noted and examples are provided from the chemical and other sciences.Until now, there has been no single publication that covers all the areas encompassed by "Modern Magnetic Resonance", by bringing together the various techniques and their applications in many scientific areas, the internationally renowned Editors have created a resource of broad appeal to the scientific community.

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Modern luminescence spectroscopy of minerals and materials

Luminescence Spectroscopy of Minerals and Materials presents an overview of the general concepts in luminescence spectroscopy as well as experimental methods and their interpretation. Special emphasis is laid on the fluorescence lifetime and the determination of time-resolved spectra. This method enables the exposure of new luminescence in minerals previously hidden by more intensive centers. Specialists in the fields of solid state physics, chemistry and spectroscopy will find a wealth of new information in this unique book.

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Modern IoT onboarding platforms for advanced applications: a practitioner’s guide to KIS.ME

There is no doubt that digitalization solutions from Industry 4.0 and the Internet of Things (IoT) can be perceived as excellent candidate strategies capable of handling the above-stated issues concerning measurements and transparency. However, IoT tools themselves can provide appropriate data only, while their efficient integration and application are possible using a dedicated onboarding platform only. To settle this issue, the book undertakes the problem of modern IoT onboarding platforms for the advanced applications pertaining to manufacturing and logistics. In particular, instead of deliberating about a possible hypothetic platforms, an existing and efficient one is employed, which is called KIS.ME. KIS.ME (Keep It Simple. Manage Everything) is a complete IoT solution for a simple integration in manufacturing and logistics.

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Modern Genome Annotation : The Biosapiens Network

An accurate description of current scientific developments in the field of bioinformatics and computational implementation is presented by research of the BioSapiens Network of Excellence. Bioinformatics is essential for annotating the structure and function of genes, proteins and the analysis of complete genomes and to molecular biology and biochemistry. Included is an overview of bioinformatics, the full spectrum of genome annotation approaches including; genome analysis and gene prediction, gene regulation analysis and expression, genome variation and QTL analysis, large scale protein annotation of function and structure, annotation and prediction of protein interactions, and the organization and annotation of molecular networks and biochemical pathways. Also covered is a technical framework to organize and represent genome data using the DAS technology and work in the annotation of two large genomic sets: HIV/HCV viral genomes and splicing alternatives potentially encoded in 1% of the human genome.

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Modern Econometric Analysis : Surveys on Recent Developments

The importance of empirical economics and econometric methods has greatly in­ creased during the last 20 years due to the availability of better data and the improved performance of computers. In an information-driven society such as ours we need quickly to obtain complete and convincing statistical results. This is only possible if the appropriate econometric methods are applied. Traditional econometric analysis concentrates on classical methods which are far from suitable for handling actual economic problems.

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Modern Developments in X-Ray and Neutron Optics

This volume describes modern developments in reflective, refractive and diffractive optics for short wavelength radiation as well as recent theoretical approaches to modelling and ray-tracing the X-ray and neutron optical systems. It is based on the joint research activities of specialists in X-ray and neutron optics from 11 countries, working together under the framework of the European Programme for Cooperation in Science and Technology (COST, Action P7) in the period 2002--2006. The chapters are written by leading specialists from European laboratories, universities and large facilities. In addition to new ideas and concepts, the contents provide a large amount of practical information about recently implemented devices and methods.

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