الصفحة 15
الصفحة 15
Drug Addiction : From Basic Research to Therapy
Drug Addiction: From Basic Research to Therapy provides a comprehensive overview of physiological, biochemical, genetic and behavioral pathways underlying drug addiction. Focusing on fundamental neurophysiological processes that overlap between drug addiction and other CNS disorders, this volume covers the translation of basic research into novel therapies, not only of drug addiction but a spectrum of related CNS disorders, including pain. Chapters are written by leading scientists with widely ranging expertise in synthetic and computational chemistry, molecular biology, genetics, neurosciences, drug discovery and development, drug targeting, and quantitative therapeutics, providing an unprecedented overview of a complex field of high societal signficance.
DNA nanotechnology for cell research : from bioanalysis to biomedicine
Bringing together multidisciplinary aspects of chemical, material, and biological engineering, DNA Nanotechnology for Cell Research: From Bioanalysis to Biomedicine presents an overview of DNA nanotechnology with emphasis on a variety of different applications in cell research and engineering, covering a unique collection of DNA nanotechnology for fundamental research and engineering of living cells, mostly in cellulo and in vivo, for the first time. Broad coverage of this book ranges from pioneering concepts of DNA nanotechnology to cutting-edge reports regarding the use of DNA nanotechnology for fundamental cell science and related biomedical engineering applications in sensing, bioimaging, cell manipulation, gene therapy, and drug delivery.
DNA Methylation and Cancer Therapy
DNA methylation pat terns emerged as the only component of the chemical structure of DNA that exhibited tissue and cell specificity. This data seemingly provided an attrac tively simple explanation for the longstanding dilemma of how could one identical genome manifest itself in so many different forms in multicellular organisms? The DNA methylation pattern has thus become the only known factor to confer upon DNA a unique cellular identity.
DNA- and RNA-Based Computing Systems
DNA- and RNA-Based Computing Systems delivers an authoritative overview of DNA- and RNA-based biocomputing systems that touches on cutting-edge advancements in computer science, biotechnology, nanotechnology, and materials science.
Distillation : Principles and practice
Distillation Principles and Practice Second Edition covers all the main aspects of distillation including the thermodynamics of vapor/liquid equilibrium, the principles of distillation, the synthesis of distillation processes, the design of the equipment, and the control of process operation.
Disinfection of root canal systems : The Ttreatment of apical periodontitis
An evidence-based manual that describes root canal anatomy, the endodontic biofilm, and the role of disinfection before presenting the most up-to-date methods of irrigation and disinfection. Individual chapters are devoted to each method, such as positive pressure irrigation, apical negative pressure irrigation, sonic activation, photodynamic therapy, laser technology, and ozonization and electrochemical activation. Clinical photographs throughout show proper irrigation and disinfection techniques.
Directory of microbicides for the protection of materials : A handbook
This edition is divided into two parts. In Part One 23 contributions of worldwide selected experts present extensively diversified information about: -Microbicides with regard to the relationship between chemical structure and mode of action and activity, -Research and development in consideration of registration procedures,Legislative aspects,The use of microbicides in the major application areas (18) which are described in detail.The Microbicide Data is organized into 21 substance classes (e.g. alcohols, aldehydes, acids, amides, etc.) and collected in Part Two.
Digital Simulation in Electrochemistry
The book shows how to numerically solve the parabolic partial differential equations (pdes) encountered in electroanalytical chemistry. It does this in a didactic manner, by first introducing the basic equations to be solved and some model systems as text cases, for which solutions exist. Then it treats basic numerical approximation for derivatives and techniques for the numerical solution of ordinary differential equations, from which the more complicated methods for pdes can be derived. The major implicit methods are described in detail, and the handling of homogeneous chemical reactions, including coupled and nonlinear cases, is detailed. More advanced techniques are presented briefly, as well as some commercially available program packages.
Dictionary of Contact Allergens
This is a concise pocket sized guide to the structures of chemicals implicated in contact dermatitis.The intended audience is physicians involved with the management of patients with contact dermatitis and allergic skin disease. This includes primary care doctors and specialists such as immunologists and dermatologists. In a broader sense, it may be of use to clinicians involved in guidelines and caring for patients in an occupational health and safety setting as well as a public health setting.
Development of statin is a breakthrough therapy in Alzheimer’s prevention
Dementia is one of the diseases which had several stages and Alzheimer’s term was selected in respect for the first doctor Alzheimer who defined the first symptoms of this diseases in a woman whom was well treated by him. The fact that this is a type of a silent disease on which you have a long-term process of neurological degradation and suddenly gives symptoms which are most often irreversible, on clinical level likely we can consider it as a malignancy, one in terms of that it is sudden shocking irreversible and on the level of behavior and some mortality beside the lack of early detection tools for diagnosis...
Detection and Disposal of Improvised Explosives
It including: Methods of detection of Improvised Explosives (IE). Methods of detection of Improvised explosives devices (IED). Disposal and safe handling of ID and IED. The treatment of detection methods may be divided in the following groups: Overview about the different methods; Trace- and vapor detection; Electromagnetic methods; Neutron methods; Laser techniques. Because of different definitions of Improvised Explosives the parti- pants of the workshop agreed after some discussions with the following definition: An Improvised Explosive (IE) can be any chemical compound or mixture capable of an explosive reaction. They are normally easily prepared by a knowledgeable layman under simple conditions. Components of IE are typically inorganic salts containing molecular bound oxygen like nitrates, chlorates or perchlorates etc. or organic compounds with nitro-, nitami- or nitrate-groups or peroxides. Admixtures of military or commercial explosive materials are also used. From the chemical point of view IE can be divided into the following types: Salts containing chemical groups with oxygen (like nitrates, chlorates or perchlorates etc.) in mixtures with combustible substances like carbon-hydrogen compounds.
Destruction of hazardous chemicals in the laboratory
Describes practical procedures for the destruction of hazardous chemicals and biological agents in the laboratory in which they are used. The book is a continuation and expansion of “Destruction of Hazardous Chemicals in the Laboratory.” It follows the same general approach as the first and second editions but includes a number of new chapters including one on using advanced oxidation techniques as a general means of degrading chemicals. All the monographs from the second edition are incorporated in this volume and are revised and extended as necessary. A number of new monographs describing procedures for the destruction of hazardous chemicals have also been added.
Desert Dust in the Global System
Dust storms, produced by the removal of surface materials from the world’s drylands, are a vital component of the environment. This is because of their role in biogeochemical cycling, their potential influence on climate, their role in sediment accumulation and their influence on human affairs. This book, which is exhaustively referenced, explores and summarises recent research on where dust storms originate, why dust storms are generated, where dust is transported and deposited, the nature of dust deposits and the changing frequency of dust storms over a range of time-scales.
Dental gold alloys and gold nanoparticles for biomedical applications
Focuses on recent advances in dental gold alloys and gold nanoparticles (GNPs) for biomedical applications. Dental gold alloys combine several highly desirable mechanical properties, such as high strength, ductility, and elasticity, with an extremely robust chemical stability in the mouth.
Dense Molecular Gas around Protostars and in Galactic Nuclei : European Workshop on Astronomical Molecules 2004
The European Workshop on Astronomical Molecules was held at ‘The Conference Building’ in Zwolle, the Netherlands, on 18–20 February 2004. The idea behind the workshop was to bring together astronomers studying similar processes in different astrophysical environments; masers and dense molecular gas around young stars and galactic nuclei. There is considerable overlap in physical and chemical phenomena between these environments, with scales ranging from circumstellar to central regions of galaxies. This issue includes 12 reviews and 27 contributed papers presented in this Wo- shop, all of them were refereed by invited speakers or the editors. The quality of the papers is outstanding. The projects discussed here are often in an early stage and undoubtedly their progress has bene?ted greatly from the opportunity to discuss results with the experts in a wide range of areas. Similarly,
Dendritic Neurotransmitter Release
This book presents recent developments in the neurophysiology of dendritic release of several chemical classes of transmitters in a number of different areas of the mammalian central nervous system. Once released from a neuron, these substances can act as neurotransmitters and/or neuromodulators, to autoregulate the original neuron, its synaptic inputs, and adjacent cells or, by volume transmission, to affect distant cells.
Defense against Bioterror : Detection Technologies, Implementation Strategies and Commercial Opportunities ; Proceedings of the NATO Advanced Research Workshop on Defense against Bioterror: Detection Technologies, Implementation Strategies and Commercial Opportunities, held in Madrid, Spain from 8 to 11 April 2004
A critical assessment of state-of-the-art of emerging ("breakthrough") biosensor technologies that will allow for the rapid identification of biological threat agents in the environment and human population, Identification of directions for future research, and to promote close working relationships between scientists from different countries and with different professional experience. The volume is devoted to a comprehensive overview of the current state of biological weapons threat; challenges confronting biodetection technologies and systems; ongoing research and development; and, future requirements. Biosensor technologies including detection platforms, networked alarm-type biodetector systems, implementation strategies, electro-optical and electrochemical biosensors.
Deep eutectic polvents : Synthesis, properties, and applications
Deep Eutectic Solvents contains a comprehensive review of the use of deep eutectic solvents (DESs) as an environmentally benign alternative reaction media for chemical transformations and processes. The contributors cover a range of topics including synthesis, structure, properties, toxicity and biodegradability of DESs. The book also explores myriad applications in various disciplines, such as organic synthesis and (bio)catalysis, electrochemistry, extraction, analytical chemistry, polymerizations, (nano)materials preparation, biomass processing, and gas adsorption.
Cyclized Helical Peptides : Synthesis, Properties and Therapeutic Applications
Constraint helical peptides have emerged as a solution to target previously undruggable protein-protein interactions, which feature large and complex surfaces. Cyclized Helical Peptides: Synthesis, Properties and Therapeutic Applications offers a review of the most current methodologies of constructing constrained helices. The authors noted experts on the topic include the information on the fundamental features of cyclized helical peptides and discuss their limitations. The book summarizes and explores the effects of chemical methods constructing helical peptides on helicity, binding affinity, cell penetration, and nonspecific toxicity
Current Developments in Solid-state Fermentation
Over the period of last two decades, there has been significant resurgence in solid-state fermentation due to the numerous benefits it offers, especially in the engineering and environmental aspects. SSF has shown much promise in the development of several bioprocesses and products. This resurgence gained further momentum during the last 5-6 years with the developments in fundamental and applied aspects. A good deal of information has been generated in published literature and patented information. Several commercial ventures have come up based on SSF in different parts of the world. The contents are organized into four parts: Part 1 deals with the General and Fundamentals aspects of SSF; Part 2 deals with the production of bulk chemicals and products such as enzymes, organic acids, spores and mushrooms in SSF; Part 3 is on the use of SSF for specialty chemicals such as gibberellic acid, antibiotics and other pharmaceutically valuable secondary metabolites, pigments, and aroma compounds; Part 4 deals with the use of SSF miscellaneous application such as SSF for food and feed applications, agro-industrial residues as substrates in SSF and the production of silage and vermicompost.
