الصفحة 15
الصفحة 15
Genetics of Adaptation
What is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.
Genetic surgery : from genes to solutions
As a tool for modifying the genome, gene editing technologies has developed rapidly in recent years, the application of these technologies in basic biomedical research has yielded significant advances in identifying and studying key molecular targets relevant to human diseases and their treatment. The clinical translation of genome editing techniques offers unprecedented biomedical engineering capabilities in the diagnosis, prevention, and treatment of disease or disability...
Genetic rogramming ; Vol. 3447 : 8th European conference, EuroGP 2005, Lausanne, Switzerland, March 30-April 1, 2005, Proceedings
In this volume we present the contributions for the 18th European Conference on Genetic Programming (EuroGP 2005). The conference took place from 30 March to 1 April in Lausanne, Switzerland. EuroGP is a well-established conf- ence and the only one exclusively devoted to genetic programming. All previous proceedings were published by Springer in the LNCS series. From the outset, EuroGP has been co-located with the EvoWorkshops focusing on applications of evolutionary computation. Since 2004, EvoCOP, the conference on evolutionary combinatorial optimization, has also been co-located with EuroGP, making this year’s combined events one of the largest dedicated to evolutionary computation in Europe. Genetic programming (GP) is evolutionary computation that solves complex problems or tasks by evolving and adapting a population of computer programs, using Darwinian evolution and Mendelian genetics as its sources of inspiration. Some of the 34 papers included in these proceedings address foundational and theoretical issues and there is also a wide variety of papers dealing with di?erent application areas, such as computer science, engineering, language processing, biology and computational design, demonstrating that GP is a powerful and practical problem-solving paradigm.
Genetic Programming ; Vol. 3905 ; 9th European Conference, EuroGP 2006, Budapest, Hungary, April 10-12, 2006. Proceedings
This book constitutes the refereed proceedings of the 9th European Conference on Genetic Programming, EuroGP 2006, held in Budapest, Hungary, in April 2006, colocated with EvoCOP 2006. The 21 revised plenary papers and 11 revised poster papers were carefully reviewed and selected from 59 submissions. The papers address fundamental and theoretical issues, along with a wide variety of papers dealing with different application areas, such as computer science, engineering, machine learning, Kolmogorov complexity, biology and computational design.
Genetic Programming ; 11th European Conference, EuroGP 2008, Naples, Italy, March 26-28, 2008. Proceedings
The 11th European Conference on Genetic Programming, EuroGP 2008, took place in Naples, Italy from 26 to 28 March in the University of Naples Congress Centre with spectacular views over the Gulf of Naples. This volume contains the papers for the 21 oral presentations and 10 posters that were presented during this time. A diverse array of topics were covered refecting the current state of research in the ?eld of Genetic Programming, including the latest work on representations, theory, operators and analysis, evolvable hardware, agents and numerous applications. A rigorous, double-blind peer review process was employed, with each s- mission reviewed by at least three members of the international Program C- mittee.
General Principles of Tumor Immunotherapy : Basic and Clinical Applications of Tumor Immunology
Brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.
Galling Arthropods and Their Associates ; Ecology and Evolution
The book addresses recent developments in the ecology, evolution, systematics, physiology, and biodiversity of gall-inducing arthropods, with individual contri butions ranging in scope from detailed descriptions to profoundly synthetic stud ies. One underlying theme of the book is the various impacts of gall induction that indirectly affect insect communities on the host plant. The other important contri bution is the highly intricate and dynamic interactions between galling arthropods and their uniquely specialized host plants. Included also are chapters that discuss biodiversity and distribution patterns of gall-inducing arthropods, and biological control of invasive gall-inducing arthropods and of invasive trees. We believe that this book makes an important contribution to the knowledge of galling arthropods and their associates and to the development of robust, general principles of the ecology and evolution of these organisms.
Galactose Regulon of Yeast : From Genetics to Systems Biology
The galactose regulon of yeast is one of the best studied regulons. It is an ideal paradigm for demonstrating fundamental and evolving concepts in biology and is used in this book as a model system to explain various facets of conventional and modern biology. The book starts with a brief historical overview on yeast research, i.e. early observations in enzyme adaptation, classical genetics, formulating hypotheses based on genetic inference. This is followed by molecular genetics of the galactose regulon, isolation of genes and testing of the hypotheses. The power of mutational analysis in deciphering molecular mechanisms is conveyed. Further, contemporary topics such as genomics, evolution, single cell analysis of transcriptional switching, binary and graded responses, biological consequences of feed back regulation in genetic circuits, and stochasticity are addressed.
Future space-transport-system components under high thermal and mechanical loads : results from the DFG Collaborative Research Center TRR40
This book presents the findings of Collaborative Research Center Transregio 40 (TRR40), initiated in July 2008 and funded by the German Research Foundation (DFG). Gathering innovative design concepts for thrust chambers and nozzles, as well as cutting-edge methods of aft-body flow control and propulsion-component cooling, it brings together fundamental research undertaken at universities, testing carried out at the German Aerospace Center (DLR) and industrial developments from the ArianeGroup
Furnishing - Zoning
Deals with the relationships between building typology and building structure, and between spatial composition and interior design. The relationship between the briefing and the catalogue of requirements, and between shell construction and fit-out, is elucidated. Connections at walls, ceilings and floors are explained in detail and illustrated with case studies of selected projects. In addition, the authors demonstrate how a well-designed sequence of spaces can create added value by means, for example, of the choice of materials and the lighting scheme, or adaptability to accommodate new functions.
Fundamentals of Space Medicine
Topics discussed in this book include: adaptation of sensory-motor, cardio-vascular, bone, and muscle systems to the microgravity of spaceflight; psychological and sociological issues of living in a confined, isolated, and stressful environment; operational space medicine, such as crew selection, training and in-flight health monitoring, countermeasures and support; results of space biology experiments on individual cells, plants, and animal models; and the impact of long-duration missions such as the human mission to Mars. The author also provides a detailed description of how to fly a space experiment, based on his own experience with research projects conducted onboard Salyut-7, Mir, Spacelab, and the Space Shuttle. Now is the time to look at the future of human spaceflight and what comes next. The future human exploration of Mars captures the imagination of both the public and the scientific community. Many physiological, psychological, operational, and scientific issues need to be solved before the first crew can explore the enigmatic Red Planet. This book also identifies the showstoppers that can be foreseen and what we need to learn to fully understand the implications and risks of such a mission.
Fundamentals of electrical drives
This brings us to the purpose of this book namely to help students and engineers appreciate and understand the fundamental concepts of modern electrical drives. An interactive learning approach is taken in this text: theory and calculations are augmented by generic models which are transposed to a simulation platform. The 'build and play' method used in this text visualizes the dynamic operation of a comprehensive set of modules ranging from an inductance to a novel 'ideal rotating transformer' (IRTF). This module is at the center of the generic models used in this text to explore the dynamic and steady state operation of grid and converter fed induction, synchronous and DC machines. The section on modulation and control emphasizes the role of power electronics and digital signal processors in drives. Downloadable files that accompany this text have an extensive set of 'build and play' tutorials, in Simulink R° and Caspoc. The latter is a simulation platform which allows direct access to the 'build and play' modules, without further licensing needs. All figures in this text are included in the downloadable files in order to help with the preparation of customized Power Point type lecture material.
Fundamentals of anatomy and physiology of speech, language, and hearing
Each topic is explored in bullet-point form with augmentative paragraph information, in-depth box features, and detailed illustrations. High-resolution Anatomage virtual dissection table figures derived from real cadavers offer an unparalleled glimpse into the anatomical structures of the human body, featuring true-to-life colors and an impressive level of detail. Topics explored include respiration, phonation, articulation, swallowing, resonance, hearing, balance, neuroanatomy, and neurophysiology.
Fundamental approaches to software engineering ; 25th International Conference, FASE 2022, Held as Part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2022, Munich, Germany, April 2–7, 2022, Proceedings
The papers deal with the foundations on which software engineering is built, including topics like software engineering as an engineering discipline, requirements engineering, software architectures, software quality, model-driven development, software processes, software evolution, AI-based software engineering, and the specification, design, and implementation of particular classes of systems, such as (self-)adaptive, collaborative, AI, embedded, distributed, mobile, pervasive, cyber-physical, or service-oriented applications.
Fundamental approaches to software engineering ; 24th International Conference, FASE 2021, Held as Part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2021, Luxembourg City, Luxembourg, March 27 – April 1, 2021, Proceedings
This book constitutes the proceedings of the 24th International Conference on Fundamental Approaches to Software Engineering, FASE 2021, which took place during March 27–April 1, 2021, and was held as part of the Joint Conferences on Theory and Practice of Software, ETAPS 2021.
Functional Biomaterials : Drug Delivery and Biomedical Applications
Explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field.
Functional and operatorial statistics
An increasing number of statistical problems and methods involve infinite-dimensional aspects. This is due to the progress of technologies which allow us to store more and more information while modern instruments are able to collect data much more effectively due to their increasingly sophisticated design. This evolution directly concerns statisticians, who have to propose new methodologies while taking into account such high-dimensional data (e.g. continuous processes, functional data, etc.). The numerous applications (micro-arrays, paleo-ecological data, radar waveforms, spectrometric curves, speech recognition, continuous time series, 3-D images, etc.) in various fields (biology, econometrics, environmetrics, the food industry, medical sciences, paper industry, etc.) make researching this statistical topic very worthwhile. This book gathers important contributions on the functional and operatorial statistics fields
Full-Chip Nanometer Routing Techniques
From a manufacturability standpoint, nanometer routers must explicitly deal with the ever increasing design complexity, and be capable of adapting to the constraint requirements of timing, signal integrity, process antenna effect, and new interconnect architecture such as X-architecture. In the nanometer era, we must look into new-generation routing technologies that combine high performance and capacity with the integration of congestion, timing, SI prevention, and DFM algorithms as the best means of getting to design closure quickly. In this book, we present a novel multilevel full-chip router, namely mSIGMA for SIGnal-integrity and MAnufacturability optimization. And these routing technologies will ensure faster time-to-market and time-to-profitability
Frontiers of high performance computing and networking – ISPA 2007 workshops ; ISPA 2007 International workshops, SSDSN, UPWN, WISH, SGC, ParDMCom, HiPCoMB, and IST-AWSN, Niagara Falls, Canada, August, 28-September 1, 2007, Proceedings
This book constitutes the refereed joint proceedings of seven international workshops held in conjunction with the 5th International Symposium on Parallel and Distributed Processing and Applications, ISPA 2007, held in Niagara Falls, Canada in August 2007.
Frontiers in Planar Lightwave Circuit Technology : Design, Simulation, and Fabrication
This book is the result of the NATO Advanced Research Workshop on Frontiers in Planar Lightwave Circuit Technology, which took place in Ottawa, Canada from September 21-25, 2004. In this volume the reader will find detailed overviews of experimental and theoretical work in high index contrast waveguide systems, micro-optical resonators, nonlinear optics, and advanced optical simulation methods, as well as articles describing emerging applications of integrated optics for medical and biological applications.
