الصفحة 14
الصفحة 14
Dental management of sleep disorders ; 2nd ed.
A clinically focused, updated, and expanded edition of the leading resource on the dental management of sleep disorders. Ddelivers a focused and authoritative exploration of the dentist’s role in managing patients with sleep problems, especially sleep-related breathing disorders and bruxism. Includes a variety of revealing case studies that examine the treatment of different sleep disorders, as well as: Thorough introductions to the societal impact of sleep disorders and human sleep architecture and functional anatomy of the airway Comprehensive explorations of the pathophysiology and classification of sleep disorders and sleep disorders in the pediatric population Practical discussions of medical disorders related to obstructive sleep apnea and the dental and orofacial consequences of sleep-related breathing disorders In-depth examinations of the role and interaction of the dentist with the sleep physician and sleep study center
Demystifying Academic Writing : Genres, Moves, Skills, and Strategies
Informative, insightful, and accessible, this book is designed to enhance the capacity of graduate and undergraduate students, as well as early career scholars, to write for academic purposes. Fang describes key genres of academic writing, common rhetorical moves associated with each genre, essential skills needed to write the genres, and linguistic resources and strategies that are functional and effective for performing these moves and skills.
Delivery of drugs ; Vol.2 : Expectations and realities of multifunctional drug delivery systems
Examines the formulation of micro-nanosized drug delivery systems and recaps opportunities for using physical methods to improve efficacy via mechano-, electroporation. The book highlights innovative delivery methods like PIPAC, including discussions on the regulatory aspects of complex injectables. Written by a diverse range of international researchers from industry and academia, the chapters examine specific aspects of characterization and manufacturing for pharmaceutical applications as well as regulatory and policy aspects.This book connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stakeholders.
Delay Differential Equations and Applications ; Proceedings of the NATO Advanced Study Institute held in Marrakech, Morocco, 9-21 September 2002
This Edition includes detailed discussion and analysis on: General Results and Linear Theory of Delay Equations in Finite Dimensional Spaces; Hopf Bifurcation, Centre Manifolds and Normal Forms for Delay Differential Equations; Functional Differential Equations in Infinite Dimensional Spaces; and Delay Differential Equations and Applications.
Deep Statistical Comparison for Meta-heuristic Stochastic Optimization Algorithms
Presents a comprehensive comparison of the performance of stochastic optimization algorithms / Includes an introduction to benchmarking and statistical analysis / Provides a web-based tool for making statistical comparisons of optimization algorithms / Overviews of the current approaches used to analyze algorithm performance in a range of common scenarios, while also addressing issues that are often overlooked. In turn, it shows how these issues can be easily avoided by applying the principles that have produced Deep Statistical Comparison and its variants. The focus is on statistical analyses performed using single-objective and multi-objective optimization data. At the end of the book, examples from a recently developed web-service-based e-learning tool (DSCTool) are presented. The tool provides users with all the functionalities needed to make robust statistical comparison analyses in various statistical scenarios. The book is intended for newcomers to the field and experienced researchers alike. For newcomers, it covers the basics of optimization and statistical analysis, familiarizing them with the subject matter before introducing the Deep Statistical Comparison approach. Experienced researchers can quickly move on to the content on new statistical approaches.
Deep learning pipeline : Building a deep learning model with TensorFlow
Build your own pipeline based on modern TensorFlow approaches rather than outdated engineering concepts. This book shows you how to build a deep learning pipeline for real-life TensorFlow projects. You'll learn what a pipeline is and how it works so you can build a full application easily and rapidly. Then troubleshoot and overcome basic Tensorflow obstacles to easily create functional apps and deploy well-trained models. Step-by-step and example-oriented instructions help you understand each step of the deep learning pipeline while you apply the most straightforward and effective tools to demonstrative problems and datasets.
Datatype-Generic Programming ; International Spring School, SSDGP 2006, Nottingham, UK, April 24-27, 2006, Revised Lectures
A leitmotif in the evolution of programming paradigms has been the level and extent of parametrisation that is facilitated — the so-called genericity of the paradigm. The sorts of parameters that can be envisaged in a programming language range from simple values, like integers and fioating-point numbers, through structured values, types and classes, to kinds (the type of types and/or classes).Datatype-generic programming is about parametrising programsby the structure of the data that they manipulate. To appreciate the importance of data type genericity,one need look no further than the internet. The internet is a massive repository of structured data, but the structure is rarely exploited. For example, compression of data can be much more efiective if its structure is known, but most compression algorithms regard the input data as simply a string of bits, and take no account of its internal organisation. Datatype-generic programming is about exploiting the structure of data when it is relevant and ignoring it when it is not. Programming languages most c- monly used at the present time do not provide efiective mechanisms for do- menting and implementing datatype genericity.
Data-driven BIM for Energy Efficient Building Design
Conceptualises the scale and spectrum of Building Information Modelling (BIM) and Artificial Intelligence (AI) approaches in energy efficient building design and to develop its functional solutions with a focus on four crucial aspects of building envelop, building layout, occupant behaviour and heating, ventilation and air-conditioning (HVAC) systems. Drawn from theoretical development on the sustainability, informatics and optimisation paradigms in built environment, the energy efficient building design will be marked through the power of data and BIM-intelligent agents during the design phase.
Database and expert systems applications ; DEXA 2020 International workshops BIOKDD, IWCFS and MLKgraphs, Bratislava, Slovakia, September 14–17, 2020, Proceedings
This volume constitutes the refereed proceedings of the three workshops held at the 31st International Conference on Database and Expert Systems Applications, DEXA 2020, held in September 2020: The 11th International Workshop on Biological Knowledge Discovery from Data, BIOKDD 2020, the 4th International Workshop on Cyber-Security and Functional Safety in Cyber-Physical Systems, IWCFS 2020, the 2nd International Workshop on Machine Learning and Knowledge Graphs, MLKgraphs2019. Due to the COVID-19 pandemic the conference and workshop were held virtually. The 10 papers were thoroughly reviewed and selected from 15 submissions, and discuss a range of topics including: knowledge discovery, biological data, cyber security, cyber-physical system, machine learning, knowledge graphs, information retriever, data base, and artificial intelligent.
Data Mining in Bioinformatics
8. 1. 1 Protein Subcellular Location The life sciences have entered the post-genome era where the focus of biological research has shifted from genome sequences to protein functionality. Withwhole-genomedraftsofmouseandhumaninhand,scientistsareputting more and more e?ort into obtaining information about the entire proteome in a given cell type. The properties of a protein include its amino acid sequences, its expression levels under various developmental stages and in di?erent tissues, its3Dstructure and activesites,its functionalandstructural binding partners, and its subcellular location. Protein subcellular location is important for understanding protein function inside the cell. For example, the observation that the product of a gene is localized in mitochondria will support the hypothesis that this protein or gene is involved in energy metabolism. Proteins localized in the cytoskeleton are probably involved in intracellular tra?cking and support.
Cutting Tool Technology : Industrial Handbook
Cutting Tool Technology provides a comprehensive guide to the latest developments in the use of cutting tool technology. The book covers new machining and tooling topics such as high-speed and hard-part machining, near-dry and dry-machining strategies, multi-functional tooling, ‘diamond-like’ and ‘atomically-modified’ coatings, plus many others.
Curcumin : clinical uses, health effects and potential complications
Curcumin is a natural product with polyphenolic structure. It is used in therapeutic remedies alone or in combination with other natural substances. Many researchers are investigating it because of its biological activities such as: anti-inflammatory, anti-cancer, anti-protozoal, anti-viral, anti-bacterial and has been found to be effective for treatment of Alzheimer, depression, headaches, fibromyalgia, leprosy, fever, menstrual problems, water retention, worms and kidney problems etc. It is an active ingredient in dietary spice, turmeric. It has reactive functional groups: a diketone moiety and two phenolic groups. Despite its unique biological activities, it suffers from some shortcomings which include: gastrointestinal problems, poor bioavailability due to its poor absorption, short half-life, poor solubility in aqueous solutions, rapid systemic elimination and antithrombotic activity which can interfere with blood clotting. The first chapter of this book reviews the different delivery systems used for incorporation of curcumin and its derivatives, release kinetics and up to date in vivo results. Chapter two discusses curcumin nano and microencapsulation and its implications on clinical uses.
CtBP Family Proteins
The Ctbp family proteins are multifunctional. They predominantly function as transcriptional corepressors in the nucleus by recruiting various histone modifying enzymes such as histone deacetylases, histone methylases and a histone demethylase. This book is a comprehensive monograph on the Ctbp family proteins.
Critical point theory and its applications
The book include extrema, even valued functionals, weak and double linking, sign changing solutions, Morse inequalities, and cohomology groups. The applications described include Hamiltonian systems, Schrödinger equations and systems, jumping nonlinearities, elliptic equations and systems, superlinear problems and beam equations. Many minimax theorems are established without the use of the (PS) compactness condition.
Cortical Deficits In Schizophrenia : From Genes to Function
Opens with a chapter by Paul Harrison highlighting the several convergence points among the diverse schizophrenia-related genes. This is followed by chapters reviewing several different specific genes, including Neuregulin, DISC-1, dysbindin, and Homer, among others, and by several chapters presenting information on physiological cortical processes that could be affected by those genes. These include glutamatergic, GABAergic and cholinergic neurotransmission.Current hot topics in schizophrenia research are also highlighted in the book. A concept that is gaining strength in the field, the chapters in this book summarize the current state of affairs in schizophrenia pathophysiology, with a consideration of genetic elements that may contribute to it. Cortical Deficits in Schizophrenia: From Genes to Function will prove a useful tool for those interested in a better understanding of schizophrenia. Even if more predisposing genes (not included in this book) become identified, the work laid out here will prove critical for assigning a functional (or dysfunctional) role to those genes. Although this is a fast-evolving field, the information and concepts covered in this book will likely be useful for years to come.
Coronaviruses : Methods and Protocols
Aims to describe a variety of techniques that reflects the wide range of research currently performed in the field of coronavirology, and begins with an overview of current understandings of coronavirus replication and pathogenesis to introduce specialists and non-specialists to the field. The rest of the book is divided into several sections of chapters beginning with those that describe identification, diagnosis, and study of the evolution of coronaviruses. The next few chapters discuss the preparation of cells and organ cultures useful in propagating coronaviruses and titration techniques, as well as techniques for analyzing virus functions that require purification of the viruses. The next chapters describe two commonly used reverse genetics techniques for coronaviruses, and techniques detailing identification of cellular receptors, binding profiles of viral attachment proteins, and virus-cell fusion. The final chapters cover a broad spectrum of techniques to identify virus-host protein-protein interactions, confirm the functional role of these proteins in virus replication, study host cell responses through genome-wide or pathway-specific approaches, and visualize virus replication complexes. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.
Convexity and Well-Posed Problems
This book deals mainly with the study of convex functions and their behavior from the point of view of stability with respect to perturbations. We shall consider convex functions from the most modern point of view: a function is de?ned to be convex whenever its epigraph, the set of the points lying above the graph, is a convex set. Thus many of its properties can be seen also as properties of a certain convex set related to it. Moreover, we shall consider extended real valued functions.
Convex functions and their applications : A contemporary approach ; 2nd ed.
This second edition provides a thorough introduction to contemporary convex function theory with many new results. A large variety of subjects are covered, from the one real variable case to some of the most advanced topics. The new edition includes considerably more material emphasizing the rich applicability of convex analysis to concrete examples. Chapters 4, 5, and 6 are entirely new, covering important topics such as the Hardy-Littlewood-Pólya-Schur theory of majorization, matrix convexity, and the Legendre-Fenchel-Moreau duality theory.
Convex Functional Analysis
This volume is dedicated to the fundamentals of convex functional analysis. It presents those aspects of functional analysis that are extensively used in various applications to mechanics and control theory. The purpose of the text is essentially two-fold. On the one hand, a bare minimum of the theory required to understand the principles of functional, convex and set-valued analysis is presented. Numerous examples and diagrams provide as intuitive an explanation of the principles as possible. On the other hand, the volume is largely self-contained. Those with a background in graduate mathematics will find a concise summary of all main definitions and theorems.
Convergence and Applications of Newton-type Iterations
Recent results in local convergence and semi-local convergence analysis constitute a natural framework for the theoretical study of iterative methods. This monograph provides a comprehensive study of both basic theory and new results in the area. Each chapter contains new theoretical results and important applications in engineering, modeling dynamic economic systems, input-output systems, optimization problems, and nonlinear and linear differential equations. Several classes of operators are considered, including operators without Lipschitz continuous derivatives, operators with high order derivatives, and analytic operators. Each section is self-contained. Examples are used to illustrate the theory and exercises are included at the end of each chapter.
