الصفحة 14
الصفحة 14
In Vitro Culture of Mycorrhizas
biologists have made important progress in understanding better the functioning of AM fungi. An in vitro technique has been developed using mycorrhizal root organ cultures, which made it possible to investigate the genetics, cell biology and physiology of AM fungi. We can now be objective enough to critically evaluate the impacts the in vitro technique has had to improve our knowledge on mycorrhizal symbiosis.
In Silico Immunology
"in silico Immunology" is a book for the future: it will summarize these emergent disciplines and, while focusing on cutting edge developments, will address the issue of synergy as it shows how these three are set to transform immunological science and the future of health care.
Improving Potassium Recommendations for Agricultural Crops
This book highlights concepts discussed at two international conferences that brought together world-renowned scientists to advance the science of potassium (K) recommendations for crops.
Improvement of Crop Plants for Industrial End Uses
This book provides concerns useful to promote an increase of the productivity of crops by using functional genomics (to understand the regulation of plant metabolism at molecular, cellular and whole plants), and the improvement of photosynthetic efficiency (to design new plants with enhanced raw materials percent and recovery).
Immunotherapy in 2020 : Visions and trends for targeting inflammatory disease
Features contributions from participants of the ESRF symposium on Immunotherapy in 2020-Visions and Trends for Targeting Inflammatory Diseases held in Potsdam near Berlin, Germany, in October 2006. The symposium presentations covered the main mechanisms of immunoregulation.
Immunosenescence
In this volume not only the mechanisms responsible for immune ageing in humans but consider what might be accomplished to redress the erosion of immune competence with age.
Immunology, phenotype first : How mutations have established new principles and pathways in immunology
This monograph deals with the impact of classical genetics in immunology, prov- ing examples of how large immunological questions were solved, and new fields opened to analysis through the study of phenotypes, either spontaneous or induced. As broad as biology has become, there are those who do not fully understand what the genetic approach is, and how it differs fundamentally from most of the methods available to natural scientists.
Immunology of Pregnancy
Reproductive Immunology is a growing area in both immunology and reproductive sciences and is helping us to better understand several complications of pregnancy. Immunology of Pregnancy is the first book to give a complete and up to date review of our knowledge related to the role of the immune system during pregnancy and the interactions between the placenta and the maternal immune system. This new title covers in detail all the different hypotheses and studies related to the immunology of implantation and provide a practical approach for the application of basic reproductive immunology research to pregnancy complications such as preeclampsia, pre-term labor and IUGR.
Immunology of fungal infections
Covers all aspects of the immunology of fungal infection. Beyond the basics, coverage includes recent developments in innate and adaptive immunological mechanisms involved in the host response to fungal infection.
Immunology and Immunopathogenesis of Malaria
This collection of reviews addresses many of these important issues of malarial immunity and immunopathology. They are of interest not only to malariologists, but hopefully also to the broader immunological community. Strong interactions with, and feedback from immunologists working in other infectious diseases and in basic immunology will help us to move the field of malaria immunology and therapeutic intervention forward more quickly.
Immunoinformatics
Immunoinformatics is an emerging subdiscipline of bioinformatics. It utilizes mathematics, information science, computer engineering, genomics, proteomics and immunological methods to bridge immunology and informatics. Similar to bioionformatics which became a driving force in genome research, immunoinformatics enables data-driven research strategies and systems approaches that aim at understanding the networks regulating the immune system. Considering the breath of topic, Immunoinformatics was composed to provide a cross-section of research ranging from data integration, epitope predictions to systems level applications. In ten chapters experts in the field introduce and discuss research strategies for immunologists and bioinformaticians who wish to endeavour existing and new approaches to gain insight into the workings of the immune system.
Immunogenicity of Biopharmaceuticals
This book is intended to give a broad overview of the current state-of-the-art regarding the immune response to biopharmaceuticals. The chapters range from an overview of the immune system and factors that may trigger the immune system, via detection of antibodies and clinical implications, to various case examples and the regulatory view on immunogenicity.
Immunogenetics of Autoimmune Disease
Utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion molecules, growth factors, antibodies, and other molecules induce and regulate critical cell functions that perpetuate inflammation, leading to tissue injury and clinical phenotype. The nature and intensity of this response as well as the physiological ability to restore homeostasis are to a large extent conditioned by the unique amino acid sequences that define allelic variants on each of the numerous participating mol ecules. Therefore, the coding genes in their germline configuration play a primary role in determining who is at risk for developing such disorders, how the disease progresses, and how someone responds to therapy. Although genetic components in these diseases are clearly present, the lack of obvious and homogeneous modes of transmission has slowed progress by prevent ing the full exploitation of classical genetic epidemiologic techniques. Furthermore, autoimmune diseases are characterized by modest disease risk heritability and m- tifaceted interactions with environmental influences. Yet, several recent discoveries have dramatically changed our ability to examine genetic variation as it relates to human disease. In addition to the development of large-scale laboratory methods and tools to efficiently recognize and catalog DNA diversity, over the past few years there has been real progress in the application of new analytical and data-manage ment approaches
Immunobiology of natural killer cell receptors
Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation, all of which cause stress in affected cells. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor. Such responses are mediated through two major effector functions, the direct cytolysis of target cells and the production of cytokines and chemokines. The authors focus here on the nature of recognition events by NK cells and address how these events are integrated to trigger these distinct and graded effector functions.
Immunity against mucosal pathogens
This book will provide the readers in the areas of vaccinology, virology, bacteriology, epidemiology, immunology and mucosal immunology within academia (undergraduate, graduate, post doctoral fellows and professors), as well as preclinical and clinical scientists in vaccine and drug industries a thorough appreciation of the mucosal immune system and its importance in protecting humans against mucosal pathogens.
Immune-Mediated Diseases : From Theory to Therapy
Includes contributions from the speakers of the Second IMD Congress (September 10-15, 2007; Moscow, Russia) who are eager to share some of the academic and clinical enthusiasm that defines the IMD meetings.
Immune regulation and immunotherapy in autoimmune disease
Assembles the insights and experience of over twenty experts and thought leaders in the field of autoimmune disease and immunotherapy. These discussions represent some of the newest concepts in autoimmune mechanisms and an array of new treatments that would have been considered science fiction only two decades ago. This book provides a wide-ranging review of two main arenas of current research: that of autoimmune mechanisms of disease and that of the latest developments in immunotherapy, with an emphasis upon multiple sclerosis.
Immune Mechanisms in Inflammatory Bowel Disease
Immune Mechanisms in Inflammatory Bowel Disease is a highly, concise update of the most recent advances in the immunobiology, genetics and microbiology related to Inflammatory Bowel Disease. This book broadly treats the topics that lead to understanding of the pathogenesis of this disease in an organized, systematic approach.
Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders
This book reviews and details experiments and theories that challenge the reader to expand their view on how IEG research is currently being used to advance our understanding of static and active brain circuits, enabling the processing, acquisition and storage of new information in healthy systems. In addition, we explore roles of IEGs in clinical neuropathology, with potential utility in molecular modeling, to highlight, on a go-forward basis, candidate mechanisms for novel targets in clinical intervention.
Imaging Cellular and Molecular Biological Functions
Imaging cellular and molecular biological function’ provides a unique selection of essays by leading experts, aiming at scientist and student alike who are interested in all aspects of modern imaging, from its application and up-scaling to its development. Indeed the philosophy of this volume is to provide student, researcher, PI, professional or provost the means to enter this applications field with confidence, and to construct the means to answer their own specific questions.
