الصفحة 12
الصفحة 12
Gut orchestra : Micro-symphony turned onco-cacophony
The role of microbiota in colorectal cancer has been studied since alterations in its composition were observed. Ever since, there are more and more pieces of evidence that microbiota could be implicated in colorectal cancer progression. Thus, the components of the microbiota could be biomarkers for the diagnosis and prognosis of colorectal cancer. It is truly important to address how the microbiota interacts with the host and how the host shapes the microbiota, in order to understand the biological pathways and mechanisms involved in their relationship and the consequences of their interactions in colorectal cancer.
Guide to Biomolecular Simulations
Molecular dynamics simulations have become instrumental in replacing our view of proteins as relatively rigid structures with the realization that they were dynamic systems, whose internal motions play a functional role. Over the years, such simulations have become a central part of biophysics. Applications of molecular dynamics in biophysics range over many areas. They are used in the structure determination of macromolecules with x-ray and NMR data, the modelling of unknown structures from their sequence, the study of enzyme mechanisms, the estimation of ligand-binding free energies, the evaluation of the role of conformational change in protein function, and drug design for targets of known structures.
Group B Coxsackieviruses
This monograph reviews information published since 1997 on the group B coxsackieviruses (CVB), a large and important group of human enteroviruses. The CVB were discovered in the mid-20th century, during the search for other poliovirus types, and within a very few years of this discovery, the CVB had been implicated as causes of human myocarditis and pancreatitis. The study of the CVB is still inextricably linked with the fate of their well-known relatives, the polioviruses, for as poliovirus eradication proceeds around the world, the CVB emerge more prominently as the enteroviruses best suited for continuing studies in enteroviral molecular biology as well as understanding the mechanisms underlying enteroviral pathogenesis. This volume reviews and presents modern views on the spectrum of CVB biologies, from interaction of the virus with its receptor through replication, speciation, and induction of disease.
Grid economics and business models ; 5th International workshop, GECON 2008, Las Palmas de Gran Canaria, Spain, August 26, 2008. Proceedings
This volume constitutes the refereed proceedings of the 5th International Workshop on Grid Economics and Business Models, GECON 2008, held in Las Palmas de Gran Canaria, Spain, August 2008.The 10 full papers included in this volume were carefully selected from 27 submission. They aim at presenting current results and innovative research in the area of grid economics. The papers are organized in topical sections on grid business modeling, market mechanisms for the grid, grid markets, and grid architectures.The proceedings are rounded off by 9 project reports that give an overview of the current and ongoing research in grid economics.
Graph Transformations ; 3rd International Conference, ICGT 2006, Rio Grande do Norte, Brazil, September 17-23, 2006, Proceedings
ICGT 2006 was the 3rd International Conference on Graph Transformation, following the previous two in Barcelona (2002) and Rome (2004), and a series of six international workshops between 1978 and 1998. The scope of the conference concerned graphical structures of various kinds (like graphs, diagrams and visual sentences) that are useful when describing complex structures and systems in a direct and intuitive way. These structures are often enriched with formalisms that model their evolution via suitable kinds of transformations. The ?eld of the conference was concerned with the theory, applications, and implementation issues of such formalisms. Particularemphasis wasputonmetamodelswhichcanaccommodateavarietyofgraphicalstructures within the same abstract theory.
Granular dynamic theory and its applications
Granular Dynamic Theory and Its Applications introduces both theory and applications in detail, including differential dynamical models of granular shearing, dynamical strength characteristics and the excited response of granules subject to vibration, granular liquefaction properties and the mechanisms under vibration, granular flow theory and vibration-aided flow, propagation laws of waves in granular media and their mechanism, fractal properties of granules, the vibrating ore-drawing technologies, and so on
Governance : Systemic foundation and framework
Instead of yet another theory on good governance, this book presents a substantiation of contemporary notions. It builds on the theoretical foundations for taking an overall perspective on social contexts and culminates in a systemic framework that captures social structures based on first principles of viability and sustainability. The framework at hand enables applicants to view social contexts holistically while at the same time envisioning a rich picture of what leverages the implementation of social purposes beyond the boxes of the professional disciplines: social structures can be assessed, strengths and weaknesses identified and measures arrived at. Ultimately, the required structures can be tailor-made to align forces for a joint implementation of purposes. Conventional static hierarchies can be deployed into dynamic social organisms capable of developing and adapting continuously according to the opportunities and challenges faced.
Glycoscience : Chemistry and Chemical Biology I-III
Glycostructures play a pivotal and crucial role in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Within recent years tools have been developed to promote the understanding of their highly complex functions and the associated chemistry and chemical biology, however, many facts still remain undiscovered.
Glucoszmine and Chondroitin between reality and tllusion
Despite the development of cancer treatments and the introduction of new treatments other than traditional treatments, the death rate is still high around the world for each type of cancer. Although conventional treatments are still common, as a first method in treatment, advanced new treatments have opened new horizon and have shown good efficacy in inhibiting cancer, either by treating them alone or in combination with conventional treatments, such as chemotherapy and radiation therapy. We mention in this research the latest methods of cancer treatment, such as targeted therapies in the treatment of solid cancers and leukemia. and will also mention the annual incidence rates of lines around the world. In cooperation with the head of the hematology division at the Mouwasat Hospital, Dr. Amin Suleiman, we studied cases of CML and MM patients being treated with modern therapies.
Global Lessons from the AIDS Pandemic : Economic, Financial, Legal and Political Implications
This book examines the global HIV/AIDS pandemic from a multidisciplinary perspective, analyzing its economic impact, the reasons behind the political response to the pandemic, international laws relating to public health and patents and mechanisms for financing global and national responses. The authors paint a global picture of the HIV/AIDS pandemic one issue, one country and one region at a time and show why prevention, treatment and human rights protection must each form part of a comprehensive HIV/AIDS strategy. The book analyzes the successes and failures of national governments, international organizations and the private sector in fighting the HIV/AIDS pandemic and recommends changes to our international economic, financial, legal and political institutions. This book highlights the lessons the world has to learn from our experience with HIV/AIDS in order to improve the way we address global diseases.
Gettering Defects in Semiconductors
The authors address not only well-established gettering techniques but also describe contemporary trends in gettering technologies from an international perspective. The types and properties of structural defects in semiconductors, their generating and their transforming mechanisms during fabrication are described. The primary emphasis is placed on classifying and describing specific gettering techniques, their specificity arising from both their position in a general technological process and the regimes of their application. This book addresses both engineers and material scientists interested in semiconducting materials theory and also undergraduate and graduate students in solid–state microelectronics and nanoelectronics. A comprehensive list of references provides readers with direction for further reading.
Gesture in Human-Computer Interaction and Simulation ; 6th International Gesture Workshop, GW 2005, Berder Island, France, May 18-20, 2005, Revised Selected Papers
The international Gesture Workshops have become the leading interdisciplinary events for dissemination of the latest results on gesture-based communication. The goal of these workshops is to bring together researchers who want to meet and share ideas on advanced research on gesture related to multidisciplinary scienti?c ?elds. Depending on the ?elds, the objectives can be very di?erent. While physiology and biomechanics aim to extract fundamental knowledge of physical gesture, computer sciences try to capture di?erent aspects of gesture and extract features that help to identify, interpret or rebuild the underlying mechanisms of communication gestures. Other approaches and methodologies are followed by cognitive sciences and linguistics, bringing a complementary - derstanding of motor control and gesture meaning. The results can be enhanced by technological applications or demonstrations.
Germ cell development : Methods and protocols
Explores techniques for the isolation, purification, and establishment of in vitro germ cell (GS) systems at different stages of development in a variety of organisms, including chickens, mice, rats, and humans. The book additionally describes cutting-edge analytic and informatic tools to study germ cell development at the single cell level and meiotic recombination. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Geotechnical Earthquake Engineering
This book presents all issues of earthquake geotechnical engineering in a comprehensive way. It summarizes the present knowledge on earthquake hazards and their causative mechanisms, experimental studies on nonlinear complex soil behaviour, an analysis to predict ground behaviour during earthquakes, field studies to determine nature of real ground as input data for analysis, and damage mitigation technologies.
Genomics in Endocrinology : DNA Microarray Analysis in Endocrine Health and Disease
Genomics in Endocrinology focuses on exciting new advances in endocrinology resulting from DNA microarray studies and includes a comprehensive introduction to the use of DNA microarrays in endocrinology. The volume provides the basis for further understanding of the usefulness of microarray analyses in endocrinology research.
Genomic intelligence : Metagenomics and artificial intelligence
The field of metagenomics has revolutionized our comprehension of microbial diversity and function across various habitats, from the human body to terrestrial and aquatic environments. Simultaneously, advancements in AI have empowered researchers to analyze vast troves of genomic data with unprecedented speed and precision, facilitating new insights into the complex interplay between microorganisms and their surroundings. Provides an overview of metagenomics and discusses the combination of metagenomics and AI and its significant consequences for advancements in science. The chapters examine the approaches, difficulties, and revolutionary uses of AI in metagenomics and provide insight into the convergence of genomics, metagenomics, and AI’s potential to revolutionize diverse fields from healthcare to environmental.
Genomes and Genomics of Nitrogen-fixing Organisms
Inthe book the first section organism based and should review our current knowledge of the genomes of nitrogen-fixing organisms and what these nucleotide sequences tell us. The second section should then be technology based. It should review what technologies are available to mine the data inherent in the nucleotide sequences and how they are now being used to produce gene-function data from differential gene expression.
Genome integrity : Facets and perspectives
The volume begins with DNA replication and continues with replicative DNA repair and pleiotropic protein interactions. Examples of human diseases are included and the cellular responses to radiation and genotoxic stress affecting whole genomes are reviewed.
Genome editing in neurosciences
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.
Genetics and regulation of nitrogen fixation in free-Living bacteria
This book is the second volume of a seven-volume series, which covers all fields of research related to nitrogen fixation - from basic studies through applied aspects to environmental impacts. Volume II provides a comprehensive and detailed source of information concerning the genetics and regulation of biological nitrogen fixation in free-living prokaryotes.
