Reference Modeling : Efficient Information Systems Design Through Reuse of Information Models
Reusability of information models has been discussed in science and practice for many years. Reference models are information models that are developed with the aim of being reused for different but similar application scenarios. They primarily promise time and cost savings, since parts of the reference models can be reused. The topic of reference modeling is addressed in this book from different perspectives:Besides reference modeling languages that provide special modeling language concepts for the development and application of reference models, reference modeling methodologies are discussed.
Reconstruction Designs of Lost Ancient Chinese Machinery
Ancient China was outstanding in mechanical technology before the 15th century. Numerous ingenious machines were invented. However, due to incomplete documentation and loss of finished objects, most of the original machines cannot be verified and many of the inventions did not pass down to later generations. This book, based on the author’s research and teaching experiences over the last 20 years, is devoted to presenting an innovative methodology in the area of mechanical historiography for the systematic reconstruction design of ancient Chinese machines that have been lost to time. Its purpose is to generate all possible design concepts of lost machines. If the defined and/or concluded design specifications, topological characteristics, and - sign requirements and constraints are feasible, one of the resulting rec- struction designs should be the original design.
Recent Advances in Thrombosis and Hemostasis
Now more than ever, thrombotic and thromboembolic disorders as well as related diseases such as malignancies, arteriosclerosis, diabetes mellitus, hypertension, and obesity are the leading causes of morbidity and mortality. They have become urgent medical problems with serious economic consequences in industrialized and devel- ing countries alike. At the same time, the impact of molecular biology and genetics on our understanding of thrombosis and hemostasis is rapidly growing stronger as well as our knowledge of regeneration and development of specific tissues, organs, and embryos. Researchers are also constantly learning more about cardiovascular diseases as well as regulatory mechanisms for various intrinsic and extrinsic stimuli in viable tissues. In this volume, our intention has been to present the latest relevant information in molecular biology and genetics as well as the clinical implications of a better understanding of pathophysiology, novel diagnostic methodologies, and therapeutic applications for new methods of prevention in thrombosis/hemostasis and related disorders, including atherosclerosis.
Recent Advances in Evolutionary Computation for Combinatorial Optimization
The application of metaheuristics to combinatorial optimisation is an active field in which new theoretical developments, new algorithmic models, and new application areas are continuously emerging. This volume presents recent advances in the area of metaheuristic combinatorial optimisation, with a special focus on evolutionary computation methods. Moreover, it addresses local search methods and hybrid approaches. In this sense, the book includes cutting-edge theoretical, methodological, algorithmic and applied developments in the field, from respected experts and with a sound perspective.
Real-Time Object Uniform Design Methodology with UML
The competitiveness of organizations facing globalization, information and communication technologies relies on strategic issues such as reuse of knowledge from past experiences to make higher quality decisions, deployment of innovative, fast methodological approaches for solving problems and building systems. Real-life systems are often multidisciplinary; their development commands a uniform way of object modeling in order to close the loop of various interactions crossing multiple domains.
Real-time Linked Dataspaces : Enabling Data Ecosystems for Intelligent Systems
Explores the dataspace paradigm as a best-effort approach to data management within data ecosystems. It establishes the theoretical foundations and principles of real-time linked dataspaces as a data platform for intelligent systems.
Realising Systems Thinking : Knowledge and Action in Management Science
This book provides a thorough evaluation of the philosophy of systems, ending up with an introduction to multimethodology and its application in real situations. This wide-ranging book deals, in a detailed and scholarly way, with the contribution of a systems approach to a range of disciplines from philosophy and biology to social theory and management. It weaves together material from some of the pre-eminent thinkers of the day — Maturana, Varela, Bateson, Merleau-Ponty, Checkland, Giddens, Habermas, Bhaskar, and Luhmann — to create a coherent path from the most fundamental work on philosophical issues of ontology and epistemology through specific domains of knowledge about the nature of information and meaning, human communication, and social intervention right up to the implications of these theoretical developments for action and intervention in real-world affairs.
Rapid integration of software engineering techniques ; 3rd International Workshop, RISE 2006, Geneva, Switzerland, September 13-15, 2006. Revised Selected Papers
RISE 2006 constituted an international forum for researchers and practitioners interested in the advancement and rapid application of novel, integrated, or pratical software engineering approaches, being part of a methodological framework, that apply to the development of either new or evolving applications and s- tems.
Radiologic Diagnosis of Gastric Cancer : A new Outlook
L.M. Portnoy is one of Russia's leading radiologists. This book is the result of his more than 30 years' experience in the field of cancer diagnosis. The author reviews for us the potentials – currently greatly underestimated – of radiological examination and the traditional X-ray for the diagnosis of gastric cancer. This comprehensive overview of methodological approaches to the X-ray examination of the stomach and corrected tumor semiotics will help practicing physicians and residents to diagnose even the most minuscule tumors. Portnoy covers all diagnostic methods related to abdominal cancer, with thorough explanations of the methodological, semiotic, and organizational aspects.
Radicals in Synthesis II : Complex Molecules
this diverse collection of topics gives a sampling of the very sophisticated and powerful methodologies utilized in the construction of complex organic small molecules using radical intermediates. Consistently, the focus is on the newest advances in the field, highlighting very recent works while providing references to valuable reviews of previous work. In a few of the early chapters, the specifics are hard to follow in instances where details are discussed but no structures are provided. However this failing only occurs in a few cases; most of the work is clearly illustrated. This Collection of thoughtfully written chapters serves to highlight the impressive efficiency and selectivity of free-radical chemistry as a powerful and rapidly developing field.
Radicals in Synthesis I : Methods and Mechanisms
Topics in Current Chemistry series highlights the importance of this rapidly growing area. The first volume, reviewed here, deals with development of new methods and the physical organic underpinnings of radical methodology, while the second volume addresses the applications of these methods in complex molecule synthesis. Although such a division is totally arbitrary, it provides a convenient platform to categorize this otherwise diverse area. ...A highly readable account of the generation and applications of alkene radical cations by heterolysis of ß-substituted radicals. The authors provide a detailed account of the methods of generation, kinetic and mechanistic aspects, and the eventual fate of these intermediates generated from diverse sources.
Radiation effects of advanced electronic devices and circuits
Aims to disclose the basic mechanisms of radiation effects for advanced devices and the breakthrough of new solutions to assess and mitigate radiation sensitivity in advanced devices and integrated circuits. This reprint presents new modeling approaches that predict how radiation impacts electronic devices and circuits. Accurate models are essential for designing devices that can tolerate radiation without significant performance degradation. We also focus on the innovative design and fabrication techniques that enhance the radiation tolerance of integrated circuits. Moreover, some discussions highlight new testing protocols and methodologies that provide more accurate and comprehensive evaluations of radiation hardness, as well as the latest advancements and trends that are of particular interest to researchers and professionals in the radiation effects community.
Race, Ethnicity and Education in Globalised Times
This book broaches what has become a ‘noisy silence’ whereby conversations about race and ethnic relationships are understood as unbalanced, irrelevant or as too dangerous to speak about. It is concerned with the ways that race and ethnic relationships are spoken about in contemporary western societies such as Australia and the changed and confused debates that underpin those discussions. Parents and teachers at one State secondary school in Melbourne, Australia speak about race and ethnic relationships as their school community is increasingly altered by globalising, technological and population change. Newspapers and public policy debates avoid discussions about race relationships even as discussions about national identity and direction are crucial themes. This book argues that race and ethnic relationships must be understood in new ways; that the analytical frameworks provided by constructivist thought and post-colonial writing must be interrogated to provide more comprehensive methodological resources to examine these relationships.
Quirky Sides of Scientists : True Tales of Ingenuity and Error From Physics and Astronomy
This enlightening book clearly demonstrates that the greatest minds throughout history arrived at their famous scientific theories in very unorganized ways. A theme running throughout the book is the notion that what is obvious today was not so in the past.
Quantum Dynamics of Complex Molecular Systems
The research summarized in this book shows that much can be done to explain phenomena in systems excited by light or through atomic interactions. It demonstrates how to tackle the multidimensional dynamics arising from the atomic structure of a complex system, and addresses phenomena in condensed phases as well as phenomena at surfaces. The chapters on new methodological developments cover both phenomena in isolated systems, and phenomena which involve the statistical effects of an environment, such as fluctuations and dissipation. The methodology part explores new rigorous ways to formulate mixed quantum-classical dynamics in many dimensions, along with new ways to solve a many-atom Schroedinger equation, or the Liouville-von Neumann equation for the density operator, using trajectories and ideas related to hydrodynamics.
Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases
Discuss the pathophysiology of autoimmune diseases in addition to both theoretical and practical aspects of quantitative pharmacology for therapeutic proteins, current translational medicine research methodologies and novel thinking in treatment paradigm strategies for IMIDs. Other notable features include: Contributions from well-known authors representing leading academic research centers, specialized contract research organizations and pharmaceutical industries whose pipelines include therapeutic proteins / Chapters on a wide range of topics (e.g., pathophysiology of autoimmune diseases, biomarkers in ulcerative colitis, model-based meta-analysis use in the development of therapeutic proteins) / Case studies of applying quantitative pharmacology approaches to guiding therapeutic protein drug development in IMIDs such as psoriasis, inflammatory bowel disease, multiple sclerosis and lupus
Quality-of-Life Research in Chinese, Western and Global Contexts
The majority of studies on the quality of life have been conducted in Western contexts and are based on Western participants. Comparatively speaking, there are only a few studies that have been conducted in different Chinese contexts. Also, there are fewer QOL studies based on children and adolescents, or studies that examine the relationship between QOL and economic disadvantage. In addition, more research is needed to address the methodological issues related to the assessment of quality of life. It is the first book to cover research in Chinese, Western and global contexts in a single volume.
Quality Of Protection : Security Measurements and Metrics
Information security in the business setting has matured in the last few decades. Standards, such as IS017799, the Common Criteria’s, and a number of industry and academic certifications and risk analysis methodologies, have raised the bar on what is considered good security solution, from a business perspective. Yet, the evaluation of security solutions has largely a qualitative flavor. Notions such as Security Metrics, Quality of Protection (QoP) or Protection Level Agreement (PLA) have only surfaced in the literature. Quality of Protection: Security Measurements and Metrics is an edited volume based on the Quality of Protection Workshop at ESORICS 2005, the flagship European Symposium on Research in Computer Security. This book discusses how security research can progress towards a notion of quality of protection in security, comparable to the notion of quality of service in networking and software measurements and metrics, in empirical software engineering.
Quality management : Reconsidered for the digital economy
Key management practices are considered and extended, including lean thinking, systems methodologies, business process reengineering, organisational learning and intelligent organisations and service quality management. This edition plays particularly close attention throughout to the impact of the 4th Industrial Revolution on quality management, revisiting the meaning of ‘quality’ in an automated and data-driven world.
Qualitative Research in European Migration Studies
Covers the main issues, challenges and techniques concerning the application of qualitative methodologies to the study of migration. It discusses theoretical, epistemological and empirical questions that must be considered before, during, and after undertaking qualitative research in migration studies. It also covers recent innovative developments and addresses the key issues and major challenges that qualitative migration research may face at different stages i.e. crafting the research questions, defining approaches, developing concepts and theoretical frameworks, mapping categories, selecting cases, dealing with concerns of self-reflection, collecting and processing empirical evidence through various techniques, including visual data, dealing with ethical issues, and developing policy-research dialogues. Each chapter discusses relative strengths and limitations of qualitative research. The chapters also identify the main drivers for qualitative research development in migration studies.



















