الصفحة 12
الصفحة 12
General Equilibrium and Welfare Economics : An Introduction
A good basic understanding of general equilibrium theory is a fundamental and indispensable background for advanced work in virtually any sub-field of economics; and a thorough understanding of the methods of welfare economics, particularly in a general equilibrium context, is indispensable for investigators undertaking applied policy analysis. This book addresses these needs and requirements by emphasizing the basic underpinnings of general equilibrium and welfare economics. In particular, the theory of choice, which is fundamental to both areas, is developed in a very comprehensive and rigorous fashion. Moreover, extensive use is made of examples, both of the simple type intended to bolster the student’s understanding of the basic concepts, and those illustrating the application of the material to field areas in economics.
Gene Therapy for Cancer
The possibility of treating cancer, a disease defined by genetic defects, by introducing genes targeting these very alterations has led to an immense interest in gene therapy for cancer. Although incremental successes have been realized, enthusiasm for gene therapy has declined due to an increasing number of obstacles. These obstacles include vector systems that do not reach systemic metastases, therapeutic genes with redundant mec- nisms allowing for cellular resistance, and toxicities in clinical trials leading to premature closure of these studies. Different tactics to overcome or circumvent these obstacles have catalyzed the development of a wide range of gene therapy approaches. Thus far, almost two-thirds of gene therapy trials have focused on cancer. This reflects the concept that gene therapy approaches for the treatment of cancer do not necessarily require long-term expression of the gene as is necessary for the treatment of primary genetic defects like hemophilia or juvenile diabetes.
Gene Expression and Regulation
This book offers a comprehensive look into the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field. Presented in the following five sections, this book covers a full spectrum of topics: The History; The Machinery; The Regulators; The Genome; and Special Topics. The Machinery section covers the transcriptional apparatus and general transcription factors. The Regulators section examines selected gene-specific transcription factors important to regulating gene expression. The Genome section covers issues relevant to the behavior of the genome in relation to gene regulation. The Special Topics section discusses several selected topics ranging from bacterial and plant gene expression to DNA topology and interference RNA. The book’s focus is on scientific concepts and issues, rather than specific organisms or experimental approaches.
Gene drives at tipping points : Precautionary technology assessment and governance of new approaches to genetically modify animal and plant populations
This book reports on a pilot project aiming at collecting information on the socio-ecological risks that could arise in the event of an uncontrolled spread of genetically engineered organisms into the environment. The researchers will, for instance, be taking a closer look at genetically engineered oilseed rape, genetically engineered olive flies as well as plants and animals with so-called gene drives. The book mainly adresses researchers.
Gender Equality Programmers in Higher Education : International Perspectives
For the last twenty years gender equality has been on the agenda of national higher education policies both within Europe and beyond it.the authors of this book analyse under which circumstances equality programmes are successful. In order to develop a deeper understanding of the mechanisms of and barriers to gender equality in higher education this book presents comparative studies and research focusing on the development of gender equality policies in different countries, as well as studies on the conditions for implementing policies, changes in strategies and the evaluation of gender equality programmes.
Garlic Extract : Interaction with mechanisms of bacterial resistance
Garlic (Allium sativum) is a medicinal plant which has a diverse biological activities including antioxidant activity, antimicrobial activity, anticancer activity and others… In this article we are focusing on its antimicrobial effect which had been tested individually and in combination with two resisted antibiotics (Ampicillin, Ciprofloxacin) on 3 gram negative bacteria (Proteus mirabilis, klebsiella pneumoniae and Enterobacter aerogenes) to estimate the effect of garlic extract on the activity of the resisted drugs and bacterial resistance mechanism.
Galling Arthropods and Their Associates ; Ecology and Evolution
The book addresses recent developments in the ecology, evolution, systematics, physiology, and biodiversity of gall-inducing arthropods, with individual contri butions ranging in scope from detailed descriptions to profoundly synthetic stud ies. One underlying theme of the book is the various impacts of gall induction that indirectly affect insect communities on the host plant. The other important contri bution is the highly intricate and dynamic interactions between galling arthropods and their uniquely specialized host plants. Included also are chapters that discuss biodiversity and distribution patterns of gall-inducing arthropods, and biological control of invasive gall-inducing arthropods and of invasive trees. We believe that this book makes an important contribution to the knowledge of galling arthropods and their associates and to the development of robust, general principles of the ecology and evolution of these organisms.
Galaxies in Turmoil : The Active and Starburst Galaxies and the Black Holes That Drive Them
Active galaxies involve some of the most extreme conditions and some of the most intriguing phenomena found anywhere in the universe. Research students - and even established research astronomers - will also find this book invaluable as a quick reference to the properties of, and phenomena within, those types of active galaxies that may be outside their specialisms.
Galactose Regulon of Yeast : From Genetics to Systems Biology
The galactose regulon of yeast is one of the best studied regulons. It is an ideal paradigm for demonstrating fundamental and evolving concepts in biology and is used in this book as a model system to explain various facets of conventional and modern biology. The book starts with a brief historical overview on yeast research, i.e. early observations in enzyme adaptation, classical genetics, formulating hypotheses based on genetic inference. This is followed by molecular genetics of the galactose regulon, isolation of genes and testing of the hypotheses. The power of mutational analysis in deciphering molecular mechanisms is conveyed. Further, contemporary topics such as genomics, evolution, single cell analysis of transcriptional switching, binary and graded responses, biological consequences of feed back regulation in genetic circuits, and stochasticity are addressed.
Fungi as an Alternative Source of Anticancer and Antioxidant
Fungi are an " excellent but underexplored source " for new therapeutic compounds. The limited availability of bioactive principles in plant sources could be surpassed by exploiting the chemical entities in the endophytes fungi . fungi represent a rich source of bioactive metabolite that can manipulated to produce desirable novel analogs. In addition to the active substances that can be extracted from the fungi, so that they are useful in several mechanisms. Exploring and exploiting of metabolites from endophytic in terrestrial, mangrove and marine habitats may provide an avenue for discovery of drug candidates against deadly human disease. This review focuses on the production of antioxidant and anticancer from severa fungi habitats.
Fungal Immunology: From an Organ Perspective
This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi.
Fungal Genomics
Presents an overview on mutualistic and pathogenic interactions between fungi and plants. This book offers reviews on fungal lifestyles, mechanisms of their interactions with their host plants, signal perception and transduction, and plant defense responses directed against attack by fungal pathogens. It is suitable for students in microbiology.
Fundamentals of Space Biology : Research on Cells, Animals, and Plants in Space
This book is intended as an overview at the undergraduate or early university level and describes the effects of spaceflight at cellular and organism levels. Past, current, and future research on the effects of gravity--or its absence--and ionizing radiation on the evolution, development, and function of living organisms is presented in layman's terms by researchers who have been active in this field. The purpose is to enlighten science and non-science readers to the benefits of space biology research for conducting basic and applied research to support human exploration of space. Also covered are the advantages of approaching the space environment as a laboratory for scientific, technological, and commercial research.
Fundamentals of Renal Pathology
This book will provide the general pathologist, pathology residents and fellows in training, the renal pathologist, and the nephrologist and nephrology resident, with a compact and up-to-date resource on the basics of renal pathology. Beginning with the basic concepts and methods in renal pathology, the text covers renal anatomy, including gross and miscroscopic appearance and pathogenic mechanisms in renal diseases.
Fundamentals of durable reinforced concrete
The book presents a framework for specification through internationally adopted codes and standards and summarises the background to probabilistic approaches to durability design, providing a state-of-the-art review of mathematical modelling of deterioration mechanisms along with current directions in test methods for performance-based specifications.
From Innate Immunity to Immunological Memory
The ability to remember an antigenic encounter for several decades, even for a life time, is one of the fundamental properties of the immune system. This phenomenon known as "immunological memory", is the foundation upon which the concept if vaccination rests. Therefore, understanding the mechanisms by which immunological memory is regulated is of paramount importance. Recent advances in immunology, particularly in the field of innate immunity, suggest that the innate immune system plays fundamental roles in influencing immunological memory. Indeed, emerging evidence suggests that events that occur early, within hours if not minutes of pathogen or vaccine entry profoundly shape the quantity, quality and duration of immunological memory. The present volume assembles a collection of essays from leading experts that span the entire spectrum research from understanding the molecular mechanisms of innate immune recognition, to dendritic cell function, to the generation and maintenance of antigen-specific B and T-cell responses.
From GSM to LTE-Advanced Pro and 5G: An Introduction to Mobile Networks and Mobile Broadband
Offers an authoritative guide to the technical descriptions of the various wireless technologies currently in use. Explains the rationale behind their differing mechanisms and implementations while exploring the advantages and limitations of each technology. Reflects the significant changes in mobile network technology that have taken place since the third edition was published. Offers a new chapter on 5G NR that explores its non-standalone and standalone architecture. In the Wi-Fi chapter, additional sections focus on the new WPA3 authentication protocol, the new 802.11ax air interface and protocol extensions like 802.11k and 11v for meshed networks.
From Fossils to Astrobiology : Records of Life on Earth and Search for Extraterrestrial Biosignatures
From Fossils to Astrobiology reviews developments in paleontology and geobiology that relate to the rapidly-developing field of Astrobiology, the study of life in the Universe. Many traditional areas of scientific study, including astronomy, chemistry and planetary science, contribute to Astrobiology, but the study of the record of life on planet Earth is critical in guiding investigations in the rest of the cosmos. In this varied book, expert scientists from 15 countries present peer-reviewed, stimulating reviews of paleontological and astrobiological studies. The overviews of established and emerging techniques for studying modern and ancient microorganisms on Earth and beyond, will be valuable guides to evaluating biosignatures which could be found in the extraterrestrial surface or subsurface within the Solar System and beyond.
Free-Radical-Induced DNA Damage and Its Repair : A Chemical Perspective
Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals have various sources, notably ionizing radiation and oxidative stress. In radiotherapy for cancer and with some anticancer drugs, use is made of cell death by excessive DNA damage. The mechanisms leading to products of free-radical attack which have been studied in models and with small double-stranded DNA fragments are discussed in detail, and the basics of the underlying free-radical chemistry are dealt with in separate chapters.
Fractals in Biology and Medicine : Beyond Planting Trees
This volume it highlights the potential that fractal geometry offers for elucidating and explaining the complex make-up of cells, tissues and biological organisms either in normal or in pathological conditions, including the structural changes that occur in tumours. It helps develop the concepts, questions and methods required in research on fractal biology and natural phenomena and to evidence the pitfalls of a too simplistic application of these principles in investigating topical subjects of biology and medicine. It discusses present and future applications of fractal geometry, bringing together cellular and molecular biology, engineering, mathematics, physics, medicine and other disciplines and allowing an interdisciplinary vision.
