الصفحة 12
الصفحة 12
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Advances in bioinformatics and computational biology ; 2nd Brazilian symposium on bioinformatics, BSB 2007, Angra dos Reis, Brazil, August 29-31, 2007, Proceedings

This book address a broad range of current topics in computationl biology and bioinformatics featuring original research in computer science, mathematics and statistics as well as in molecular biology, biochemistry, genetics, medicine, microbiology and other life sciences.

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Advances in Bioactivation Research

This volume provides researchers with recent information on bioactivation reactions of drugs and toxicants. In other sections, focus is on recent applications of bioactivation research in pharmacology, toxicology, and environmental health sciences, where contributors demonstrate the integration of bioactivation research.

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Advances in Alzheimer’s and Parkinson’s Disease : Insights, Progress, and Perspectives

Proceedings of the 7th International Conference on Alzheimer’s Disease and Parkinson’s Disease (ADPD), held March 9-13, 2005 in Sorrento, Italy.The subject matter of the ADPD conferences is unique in that it deals not only with issues related individually to Alzheimer’s disease and Parkinson’s disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, covering topics such as immunology, neuroscience, pharmacology, genetics, molecular biology, biochemistry and the history, epidemiology, clinical phenomenology, diagnosis, imaging, treatment ,and future perspectives of Alzheimer’s and Parkinson’s Diseases.

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Advanced chemical biology : chemical dissection and reprogramming of biological systems

Organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections.

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Adipose Tissue and Adipokines in Health and Disease

The aim of Adipose Tissue and Adipokines in Health and Disease is to provide comprehensive information regarding adipose tissue, its physiological functions and its role in disease. This volume contains a collection of information spanning the entire range of adipose tissue studies, from basic anatomical and physiological research to epidemiology and clinical aspects, in one place. This book is indispensable for basic researchers and clinicians interested in the fields of obesity, metabolic diseases, inflammation and immunity, and specialists in each of the pathologies associated with obesity.

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Acute Promyelocytic Leukemia : Molecular Genetics, Mouse Models and Targeted Therapy

Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy.

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Acute Myelogenous Leukemia

The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. Bringing together new concepts and findings in the basic and clinical science of AML, the book emphasizes the molecular basis for new therapies that stand to have the greatest potential impact on the clinical face of these diseases. The text provides insights into selected novel strategies currently and prospectively being developed, including interruption of specific signal transduction pathways, modulation of gene expression, attempts to reinstate differentiation, and immunomodulation.

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Actin-Binding Proteins and Disease

This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin ¾4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.

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Accessing and Sharing the Benefits of the Genomics Revolution

This edited volume explores the legal, economic and political context for the debate about intellectual property rights for traditional knowledge and genetic resources and critically analyses the theory and practice of access and benefits sharing efforts around the world. The book also investigates the current flashpoints—the David and Goliath battle between Monsanto and Percy Schmeiser over farmers’ rights; the dispute over coexistence of GM and organic production; and the ownership and control of human genetic materials stored in human gene banks around the world.

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Abnormal Skeletal Phenotypes : From Simple Signs to Complex Diagnoses

This book focuses on the radiographic changes of malformation syndromes and skeletal dysplasias. It is structured such that the reader can identify the radiographic changes and relate them to specific disease entities. The aim is to provide an essential, practical guideline to the recognition of the key radiographic signs for diagnosing malformation syndromes and skeletal dysplasias.

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Abeta Peptide and Alzheimers Disease : Celebrating a Century of Research

Abeta Peptide and Alzheimer’s Disease summarizes current knowledge of beta-amyloid peptide (Aß) and its role as the major culprit in Alzheimer’s Disease (AD), shown by recent advances in genetics and brain biochemistry.the book covers fundamental biochemical studies on the Aß peptide, the genetic impact on Aß expression and processing, and various AD therapeutic strategies that target Aß. Although specifically focusing on Aß and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases.

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A Multidisciplinary Approach to Capability in Age and Ageing

This book provides insight on how to interpret capability in ageing – one’s individual ability to perform actions in order to reach goals one has reason to value – from a multidisciplinary approach. the book describes this demographic trends as well as the large global challenges and important societal implications this will have such as a worldwide increase in the number of persons affected with dementia, and in the ratio of retired persons to those still in the labor market. Through contributions from many different research areas, it discussed how capability depends on interactions between the individual (e.g. health, genetics, personality, intellectual capacity), environment (e.g. family, friends, home, work place), and society (e.g. political decisions, ageism, historical period).

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A Life (Un)Worthy of Living: Reproductive Genetics in Israel and Germany

This book presents the findings of a study into the social shaping of reproductive genetics in Germany and Israel, two exceptionally interesting social settings, which share a traumatic history. ‘This is a unique and courageous book. Yael Hashiloni-Dolev studied the field of reproductive genetics in Israel and Germany, and found out that while in Germany social, cultural, legal and religious conditions restrict the selection of embryos based on prenatal diagnosis, it is strongly encouraged in Israel. This unexpected finding is brilliantly analyzed by the author. Thus this excellent book must be read and discussed by social scientists, human geneticists, genetic counsellors, bio ethicists and medical students.'

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A Dictionary of Public Health

This dictionary covers terms used in public health science and practice, including areas such as communicable disease control, epidemiology, genetics, nutrition, toxicology, social work, sanitation and public health engineering, environmental sciences, and administration. It offers definitions, discussion, and an occasional brief commentary on the relevance of each term to people and their health.

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A Dictionary of Biomedicine

A Dictionary of Biomedicine fills the need to define the specialist language used within an evolving field by offering clear, concise definitions of even the most complex biomedical terms. It includes more than 10,000 A-Z entries on all areas of biomedicine, such as genomics and biomedical science. Entries are authoritative and wide-ranging, covering terms from the related areas of anatomy, genetics, molecular bioscience, pathology, pharmacology, and clinical medicine.

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A Changing World : Challenges for Landscape Research

"Written primarily for researchers and advanced students in environmental and social sciences, this latest book in Springer’s Landscape Series looks at some of the emerging fields and new challenges in landscape research. These include: the role of value systems in perceiving, appreciating, and managing landscapes / the ‘space’ and ‘place’ concept in landscape research GIS and remote sensing techniques for gathering and processing spatially and temporally explicit land cover, vegetation, and land use data / methods of landscape history / landscape genetics and genetic methods to test landscape connectivity and dispersal of plant and animal species"

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37th Hemophilia Symposium ; Epidemiology : Treatment of Inhibitors in Hemophiliacs ; Hemophilic Arthropathy and Synovitis ; Relevant Hemophilia Treatment 2006 ; Pediatric Hemostasiology; Free Lectures

This book contains the contribution to the 37th Hemophilia Symposium, Hamburg 2006. The main topics are epidemiolgy, treatment of inhibitors in hemophiliacs, hemophilic arthropathy and synovitis, relevant hemophilia treatment 2006, and pediatric hemostasiology.

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(R)Evolution : Organizations and the Dynamics of the Environment

Investigates the possible changes needed for industrial organizations to adapt to and remain competitive in their ever evolving environment. (R)Evolution’s main area of contribution to these very complex issues is embedded in the work’s ambitious attempt to borrow from evolutionary biology and genetics not only metaphors but also concepts and models to be adapted to the management of business organizations. The work provides us with a comprehensive vision of adaptation and variation in the business community, integrating various intellectual inputs which are based on an evolutionary vision of economic behavior. Using an extensive study of the literature in management science, and applying new models and methodologies in numerous case studies, Dekkers draws many insightful conclusions including the claim that companies often evolve slower than generally expected. Furthermore the research calls into question the effectiveness of the common practice of corporate reorganization. Embracing and merging most major contemporary developments in the theories of change into a comprehensive integrated approach, (R)Evolution is an invaluable resource for researchers specializing in the management of technological change.

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