Advances in Alzheimer’s and Parkinson’s Disease : Insights, Progress, and Perspectives
Proceedings of the 7th International Conference on Alzheimer’s Disease and Parkinson’s Disease (ADPD), held March 9-13, 2005 in Sorrento, Italy.The subject matter of the ADPD conferences is unique in that it deals not only with issues related individually to Alzheimer’s disease and Parkinson’s disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, covering topics such as immunology, neuroscience, pharmacology, genetics, molecular biology, biochemistry and the history, epidemiology, clinical phenomenology, diagnosis, imaging, treatment ,and future perspectives of Alzheimer’s and Parkinson’s Diseases.
Advanced Intelligent Computing Theories and Applications. With Aspects of Theoretical and Methodological Issues ; 4th International Conference on Intelligent Computing, ICIC 2008 Shanghai, China, September 15-18, 2008 Proceedings
This book - in conjunction with the two volumes CCIS 0015 and LNAI 5226 - constitutes the refereed proceedings of the 4th International Conference on Intelligent Computing, ICIC 2008, held in Shanghai, China, in September 2008.
Advanced Intelligent Computing Theories and Applications : With Aspects of Contemporary Intelligent Computing Techniques ; 3rd International Conference on Intelligent Computing, ICIC 2007 Qingdao, China, August 21-24, 2007 Proceedings
The International Conference on Intelligent Computing (ICIC) was formed to provide an annual forum dedicated to the emerging and challenging topics in artificial intelligence, machine learning, bioinformatics, and computational biology, etc. It aims to bring - gether researchers and practitioners from both academia and industry to share ideas, problems and solutions related to the multifaceted aspects of intelligent computing.This year, the conference concentrated mainly on the theories and methodologies as well as the emerging applications of intelligent computing. Its aim was to unify the picture of contemporary intelligent computing techniques as an integral concept that highlights the trends in advanced computational intelligence and bridges theoretical research with applications.
Advanced chemical biology : chemical dissection and reprogramming of biological systems
Organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections.
Acute Myelogenous Leukemia
The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. Bringing together new concepts and findings in the basic and clinical science of AML, the book emphasizes the molecular basis for new therapies that stand to have the greatest potential impact on the clinical face of these diseases. The text provides insights into selected novel strategies currently and prospectively being developed, including interruption of specific signal transduction pathways, modulation of gene expression, attempts to reinstate differentiation, and immunomodulation.
About Life : Concepts in Modern Biology
This book uses modern biological knowledge to tackle the question: "What distinguishes living organisms from the non-living world?" In the first few chapters, the authors draw on recent advances in cell and molecular biology to develop an account of the "living state" that applies to all organisms, but only to organisms. Subsequent chapters use this account to explore questions about evolution, the origin of life and the possibility of extraterrestrial life. Towards the end of the book the authors consider human evolution, intelligence and the extent to which our species can be regarded as biologically unique. About Life is written as far as possible in non-technical language; all scientific terms are explained straightforwardly when they are introduced. It is aimed at the general, non-specialist reader, but the novel approach that it takes to general issues in biology will also interest students of the life sciences.
A Guide to Methods in the Biomedical Sciences
A Guide to Methods in the Biomedical Sciences gives a basic description of common methods used in research. This is not intended to be a methods book. Rather, it is intended to be a book that outlines the purpose of the methods described, their limitations and provide alternative approaches as appropriate. Thousands of methods have been developed in the various biomedical disciplines and those covered in this book represent the basic, essential and most widely used methods in several different disciplines. The historical background (including some interesting anecdotes) leading to the development of ground-breaking techniques are described, especially those that significantly advanced the field of biomedical research. Advances that earned their inventors prestigious Nobel Prizes are emphasized. The book is divided into six sections, highlighting selected methods in protein chemistry, nucleic acids, recombinant DNA technology (including forensic based methods), antibody-based techniques, microscopy and imaging, and the use of animals in biomedical sciences.
25 Years of P53 Research
Communication, awareness and access to information: Given the complexity of the field and the fact that data pertaining to each particular aspects of p53 biology or deregulation are scattered in many different publications, it is extremely difficult to access the full scale of relevant information of any specific p53-related topic. This book may help in this task by putting into perspective both general considerations on the p53 pathway and more specific information on various aspects of p53. In the longer term, however, open access to p53 complexity will require the development of knowledge bases accessible through the web and using simple navigation tools to guide users towards the specific information they need. Several efforts are currently being developed in that direction. They need to be strenghtened and better integrated within the rapidly growing galaxy of web-based information sources on molecular and individual variations in cancer. 2. Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard, universally accepted assays to measure critical p53 protein functions.







