الصفحة 12
الصفحة 12
Data and Text Processing for Health and Life Sciences
This book is a step-by-step introduction on how shell scripting can help solve many of the data processing tasks that Health and Life specialists face everyday with minimal software dependencies. The examples presented in the book show how simple command line tools can be used and combined to retrieve data and text from web resources, to filter and mine literature, and to explore the semantics encoded in biomedical ontologies. To store data this book relies on open standard text file formats, such as TSV, CSV, XML, and OWL, that can be open by any text editor or spreadsheet application.
Cytokines in the Genesis and Treatment of Cancer
Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. Divided into four sections, the volume’s first three parts focus on cytokines in the genesis of cancer. The final section describes the notable progress — both in animal models and humans — in demonstrating the use of cytokine or anticytokine therapies for the prevention and treatment of cancer. Cytokines in the Genesis and Treatment of Cancer brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer. Together, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field.
Cytokines and Cancer
This volume provides a comprehensive review of the current knowledge on cytokines and cancer. Cytokines play a variety of roles in cancer, both as components of pathogenetic mechanisms, as well as agents used in the treatment of certain malignancies.The volume is divided in two sections. Section one focuses on current developments in the basic science field with particular emphasis on novel mechanisms of cytokine actions in malignant cells. The second section deals with translational and clinical research in the field, and many of the chapter authors were among the first to introduce several cytokines in the treatment of certain tumors.
Cyanobacterial Harmful Algal Blooms : State of the Science and Research Needs
Humans can be exposed to cyanobacterial toxins by drinking water that contains the toxins, swimming in water that contains high concentrations of cyanobacterial cells, or breathing air that contains cyanobacterial cells or toxins (while watering a lawn with contaminated water, for example). Health effects associated with exposure to high concentrations of cyanobacterial toxins include: - stomach and intestinal illness; -trouble breathing; - allergic responses; - skin irritation; - liver damage; and neurotoxic reactions, such as tingling fingers and toes. Scientists are exploring the human health effects associated with long-term exposure to low levels of cyanobacterial toxins. Some studies have suggested that such exposure could be associated with chronic illnesses, such as liver cancer and digestive-system cancer. This monograph contains the proceedings of the International Symposium on Cyanobacterial Harmful Algal Blooms held in Research Triangle Park, NC, September 6-10, 2005.
Current Topics in Complement
Complement has been regarded as a pivotal effector arm of the innate immune response. Many scientists convened at the Third Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics, to discuss the advances in this field. This volume represents a collection of topics discussed during the conference.
Current Perspectives in microRNAs (miRNA)
In this book, many new perspectives of the miRNA research are reviewed and discussed, including their roles in stem cell maintenance, embryonic development, tissue differentiation, adult physiology, disease pathology, cancer research, viral infection, genetic engineering in plants, and utility in cosmetic applications. These new findings may not only provide significant insight into the various mechanisms of miRNAs but also offer a great opportunity in developing new therapeutic interventions.
Current Drug Synthesis
Delivers an authoritative and comprehensive discussion of the medicinal chemistry of current drugs, as well as the cutting-edge science involved in their synthesis. The book demystifies the process of modern drug discovery for both industry practitioners and students, while capturing the state-of-the-art techniques used to discover some of the most impactful medicines on the market today. Covering six different disease areas – including infectious disease, cancer, cardiovascular and metabolic disease, the central nervous system, anti-inflammatory disease, and a miscellaneous section – the book explores 18 different drugs before concluding with chapters on computational drug discovery and peptide drugs.
Cured II - LENT Cancer Survivorship Research and Education : Late Effects on Normal Tissues
Multimodal treatment lies at the heart of the improvement in cancer cure rates. However, the more aggressive the treatment delivery in terms of dose, time and volume for radiation and chemotherapy, the more adverse effects in normal tissues can be anticipated. Against this background, a major paradigm shift has taken place in that there is a new focus on cancer survivorship. Put another way, there has been a realization that prolongation of life must be accompanied by maintenance of the quality of life: the life worth saving must be worth living.
Curcumin : clinical uses, health effects and potential complications
Curcumin is a natural product with polyphenolic structure. It is used in therapeutic remedies alone or in combination with other natural substances. Many researchers are investigating it because of its biological activities such as: anti-inflammatory, anti-cancer, anti-protozoal, anti-viral, anti-bacterial and has been found to be effective for treatment of Alzheimer, depression, headaches, fibromyalgia, leprosy, fever, menstrual problems, water retention, worms and kidney problems etc. It is an active ingredient in dietary spice, turmeric. It has reactive functional groups: a diketone moiety and two phenolic groups. Despite its unique biological activities, it suffers from some shortcomings which include: gastrointestinal problems, poor bioavailability due to its poor absorption, short half-life, poor solubility in aqueous solutions, rapid systemic elimination and antithrombotic activity which can interfere with blood clotting. The first chapter of this book reviews the different delivery systems used for incorporation of curcumin and its derivatives, release kinetics and up to date in vivo results. Chapter two discusses curcumin nano and microencapsulation and its implications on clinical uses.
Critical Issues in Head and Neck Oncology : Key Concepts from the Seventh THNO Meeting
This book discusses the most current issues in head and neck cancer with a focus on current trends such as biomarkers, precision medicine and immunotherapy. New approaches in the diagnosis such as liquid biopsies and imaging biomarkers to predict radiotherapy toxicity as well as approaches in the surgical management of head and neck cancers are discussed. The book discusses medical and surgical approaches in both primary, recurrent and metastatic disease and also covers approaches for rare head neck cancers
Critical issues in head and neck oncology : Key concepts from the eighth THNO meeting
Reviews the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches.
Controversies in laparoscopic surgery
Thistextbook purpose is to specifically address topics of controversy in this rapidly evolving field. The book is aimed not only at the 'dedicated' laparoscopic surgeon, but also at general surgeons and surgical trainees. The aim of each chapter is to define, sharpen and emphasize issues of controversy, using the available evidence.
Consumer Health Informatics : Informing Consumers and Improving Health Care
This comprehensive volume the inclusion of several case studies serves to examine pertinent topics, namely computer-based information for cancer; National Library of Medicine initiatives; and web-based patient preferences and utilities. Designed for use by medical IT specialists, physicians, nurses, healthcare providers, and professors and students of medical informatics, the book's chapter highlights include patient empowerment; frameworks and models for health behavior change and patient education; patient to patient communication; patient to provider communication; privacy and confidentiality; ethical issues; evaluation methods, and more.
Constructions of cancer in early Modern England : Ravenous natures
Cancer is perhaps the modern world's most feared disease. Yet, we know relatively little about this malady's history before the nineteenth century. This book provides the first in-depth examination of perceptions of cancerous disease in early modern England. Looking to drama, poetry and polemic as well as medical texts and personal accounts, it contends that early modern people possessed an understanding of cancer which remains recognizable to us today. Many of the ways in which medical practitioners and lay people imagined cancer – as a 'woman's disease' or a 'beast' inside the body – remain strikingly familiar, and they helped to make this disease a byword for treachery and cruelty in discussions of religion, culture and politics. Equally, cancer treatments were among the era's most radical medical and surgical procedures. From buttered frog ointments to agonizing and dangerous surgeries, they raised abiding questions about the nature of disease and the proper role of the medical practitioner.
Concise Manual of Hematology and Oncology
In this book, we have started to systematically capture and evaluate data on diagnosis, treatment, and outcomes of p- tients with solid tumors and hematological neoplasms at the Freiburg University Med- cal Center.
Computational methods for rational drug design
Covers the tools and techniques of drug design with applications to the discovery of small molecule-based therapeutics, detailing methodologies and practical applications and addressing the challenges of techniques like AI/ML and drug design for unknown receptor structures. Divided into 23 chapters, the contributors address various cutting-edge areas of therapeutic importance such as neurodegenerative disorders, cancer, multi-drug resistant bacterial infections, inflammatory diseases, and viral infections.
Combination therapy against multidrug resistance
Explores strategic methods with investigation of both short- and long-term goals to combat multidrug resistance Presents a broad scope to understand fully the ways to apply combined therapy to multidrug resistance Provides an overview of combination therapy, but also includes specific cases such as cancer, tuberculosis, HIV and malaria
Colorectal Cancer : Evidence-based Chemotherapy Strategies
The clinician is challenged to keep up with the rapidly changing landscape and the rapidly emerging data that shape the options for treatment today and tom- row. In this text, leaders in the management of colorectal cancer review the current literature that has led us to where we are today. Critical evaluations of the data are offered, and evidence-based recommendations are made.
Color Atlas of Immunocytochemistry in Diagnostic Cytology
Color Atlas of Immunocytochemistry in Diagnostic Cytology is an illustrated practical handbook that allows for quick reference in the selection and interpretation of markers in specific differential diagnoses in the daily practice of Diagnostic Cytology. This atlas includes 299 color illustrations.
Color Atlas of Histopathology of the Cervix Uteri
The new edition of this atlas integrates all significant advances made in the past 15 years in molecular pathology, tumor virology, and genetics of cervical cancer. It emphasizes the importance of these advances in facilitating its pathological diagnosis and in op- mizing clinical management and prognosis.
