الصفحة 116
الصفحة 116
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Chemistry and Safety of Acrylamide in Food

Specifically covered are the following aspects: exposure from the environment and the diet; biomarkers of exposure; risk assessment; epidemiology; mechanism of formation in food; biological alkylation of amino acids, peptides, proteins, and DNA by acrylamide and its epoxide metabolite glycidamide; neurotoxicity, reproductive toxicity, and carcinogenicity; protection against adverse effects; and possible approaches to reducing levels in food. Cross-fertilization of ideas among several disciplines in which an interest in acrylamide has developed, including food science, pharmacology, toxicology, and medicine, will provide a better understanding of the chemistry and biology of acrylamide in food, and can lead to the development of food processes to decrease the acrylamide content of the diet.

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Chemistry and pharmacology of drug discovery

Illustrates how chemistry, biology, pharmacokinetics, and a host of disciplines come together to produce successful medicines, discussing a total of 20 drugs that are all FDA-approved post 2021. Cover Infectious Disease, Cancer Drugs, CNS Drugs, and Miscellaneous Drugs. Each chapter covers background material on the drug class and/or disease indication and key aspects relevant to the discovery of the drug, including structure-activity relationships, pharmacokinetics, drug metabolism, efficacy, and safety.

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Chemical Sensors : An Introduction for Scientists and Engineers

Research in the area of chemical and biochemical sensors and the development of respective applications is still growing rapidly. In the last decade it has become evident that the successful development of chemical and biochemical sensors resistant to the harsh conditions in the various routine applications calls for a cooperation between chemists and engineers.Thus, this book aims at instructing researcher and practitioners in both disciplines in a strictly systematic, interdisciplinary and practice-oriented way about the basic technology of chemical and biochemical sensors. This concise volume bridges the gap between the different "ways of thinking" in chemistry, physics and engineering

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Chemical Genomics ; Vol.58 : Small Molecule Probes to Study Cellular Function

Chemical genomics is a highly interdisciplinary and very exciting field of research both in academics and in the life sciences industry.Various aspects of the interface between chemistry and biology are covered in this volume, such as chemogenomics efforts in the pharmaceutical industry, diversity-oriented synthesis, chemogenomic approaches to the study of cell function, screening technologies, and natural products as tools in chemical biology.

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Chemical Biology of Neurodegeneration : A Molecular Approach

This book focuses on the main actors involved in neurodegenerative disorders at a molecular level, and places special emphasis on structural aspects and modes of action. Drawing on recent data on enzyme structure, mode of action, and inhibitor design, it describes?from a biochemical point of view?the six most important neurotransmitter systems and their constituent enzymes and receptors. Misfolding and aggregation of proteins within the brain is also covered.

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Charting Spiritual Care : The emerging role of Chaplaincy Records in Global Health Care

This book is the first academic book on the controversial issue of including spiritual care in integrated electronic medical records (EMR). Based on an international study group comprising researchers from Europe (The Netherlands, Belgium and Switzerland), the United States, Canada, and Australia, this edited collection provides an overview of different charting practices and experiences in various countries and healthcare contexts.

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Charity Law & Social Policy : National and International Perspectives on the Functions of the Law Relating to Charities

Charity Law & Social Policy explores contemporary law, policy and practice in a range of modern common law nations. It does so in four parts and from the perspective of how this has evolved in the UK.As progenitor of a system bequeathed to its colonies and after centuries of leadership in developing the core principles, policies and precedents that subsequently shaped its development, the contribution of England & Wales, the originating jurisdiction, is first described and analysed in detail.

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Charismatic Christianity in Finland, Norway, and Sweden : Case Studies in Historical and Contemporary Developments

The history of Charismatic Christianity in the Nordic countries reaches as far back as Pentecostalism itself. The bounds of these categories remain a topic of discussion, but Nordic countries have played a vital role for developing this rapidly spreading form of world-wide Christianity. Until now, research on global Charismatic Christianity has largely overlooked the region. This book addresses and analyzes its historical and contemporary trajectories in Finland, Norway and Sweden. Through a selection of cases written by Nordic scholars from various disciplines, it demonstrates historical and contemporary diversity as well as interconnections between local, national, and global currents. Highlighting change and continuity, the anthology reveals new aspects of Charismatic Christianity.

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Charging the Internal Combustion Engine

The purpose of this book is to facilitate a better understanding of the characteristics of superchargers in respect to their physical operating principles, as well as their interaction with piston engines. This applies both to the displacement compressor and toexhaustgas turbocharging systems,whichoftenareverycomplex.

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Charged Particle Traps : Physics and Techniques of Charged Particle Field Confinement

This book provides an introduction and guide to modern advances in charged particle (and antiparticle) confinement by electromagnetic fields. Confinement in different trap geometries, the influence of trap imperfections, classical and quantum mechanical description of the trapped particle motion, different methods of ion cooling to low temperatures, and non-neutral plasma properties (including Coulomb crystals) are the main subjects. They form the basis of such applications of charged particle traps as high-resolution optical and microwave spectroscopy, mass spectrometry, atomic clocks, and, potentially, quantum computing.

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Charge Migration in DNA : Perspectives from Physics, Chemistry, and Biology

Charge migration through DNA has been the focus of considerable interest in recent years. A deeper understanding of the nature of charge transfer and transport along the double helix is important in fields as diverse as physics, chemistry and nanotechnology. It has also important implications in biology, in particular in DNA damage and repair. This book presents contributions from an international team of researchers active in this field.

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Characterization of Polymer Surfaces and Thin Films

Comprehensive characterization of surfaces and interfaces is essential to relate surface and thin film properties to micro structure and molecular origin, which is, on the other hand, the key to technological control and improvement of materials. This volume cover a representative spectrum of surface sensitive techniques and their application to polymer surface and thin film characterization as well as recent examples of technologically relevant materials and process development.

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Characterization of Corrosion Products on Steel Surfaces

It is well known that corrosion products, i.e. rust, on iron and steel surfaces cannot be assigned a typical crystallographic structure with long-range order. In fact, the structure of rust is considered to be very complicated, and some forms of rust are assigned to the amorphous state for this reason. Accurate information about the atomic-scale structure of rust is important to shed light on corrosion mechanisms of metallic materials. And, since life of steel structures is often dominated by environmental degradation or corrosion of the surface, the structure of the rust formed on iron and steel surfaces during prolonged exposure to air is of great interest. This book describes the fundamental aspects of materials characterization for the ferric oxyhydroxides formed on steel surfaces.

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Characterization II

Molecular Sieves - Science and Technology covers, in a comprehensive manner, the science and technology of zeolites and all related microporous and mesoporous materials. Authored by renowned experts, the contributions to this handbook-like series are grouped together topically in such a way that each volume deals with a specific sub-field. Volume 5 complements Volume 4 (Characterization I) in that it is devoted to the characterization of molecular sieves by a variety of non-spectroscopic techniques (Characterization II). Thus, Volume 5 comprises Chemical Analysis, Thermal Analysis, Pore-Size Characterization by Molecular Probes, Characterization by 129Xe NMR, Coke Characterization, Synthesis and Characterization of Isomorphously Substituted Molecular Sieves.

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Changing Forests : Collective Action, Common Property, and Coffee in Honduras

It merges political ecology, collective-action theories, and institutional analysis to study how the people and forests have changed through socioeconomic and political transitions. It studies the complex, often contradictory relationships between the people and their natural resources to understand why forest cover endures."Changing Forests" therefore encompasses three broad phases: (1) the premodern period, which considers historic perturbations in western Honduras from the period of colonialism into the middle of the twentieth century; (2) the period of state-led logging and intervention in La Campa, which caused major degradation in forest cover; and (3) the recent period in which export coffee production transformed property rights, and people’s perceptions of the forest gained new conservationist and economic dimensions. Each phase entails perspectives and experiences that influenced human use of forests, and shaped subsequent transformations.

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Changing Aspects in Stroke Surgery : Aneurysms, Dissections, Moyamoya Angiopathy and EC-IC Bypass

What is arterial dissection? What is Moyamoya angiopathy? What is the state of art of AVM treatment? Readers will find answers to these questions in this book. But they will also be informed about the state of the art treatment in the daily stroke therapy.

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Chance Rules : An informal guide to probability, risk and statistics

This second edition of Chance Rules again recounts the story of chance through history and the various ways it impacts on our lives. Here you can read about the earliest gamblers who thought that the fall of the dice was controlled by the gods, as well as the modern geneticist and quantum theory researcher trying to integrate aspects of probability into their chosen speciality. Example included in the first addition such as the infamous Monty Hall problem, tossing coins, coincidences, horse racing, birthdays and babies remain, often with an expanded discussion, in this edition. Additional material in the second edition includes, a probabilistic explanation of why things were better when you were younger, consideration of whether you can use probability to prove the existence of God, how long you may have to wait to win the lottery, some court room dramas, predicting the future, and how evolution scores over creationism. Chance Rules lets you learn about probability without complex mathematics.

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Chance Discoveries in Real World Decision Making : Data-based Interaction of Human intelligence and Artificial Intelligence

For this book, the editors invited and called for contributions from indispensable research areas relevant to "chance discovery," which has been defined as the discovery of events significant for making a decision, and studied since 2000. From respective research areas as artificial intelligence, mathematics, cognitive science, medical science, risk management, methodologies for design and communication, the invited and selected authors in this book present their particular approaches to chance discovery. The chapters here show contributions to identifying rare or hidden events and explaining their significance, predicting future trends, communications for scenario development in marketing and design, identification effects and side-effects of medicines, etc.

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Challenges to the second law of thermodynamics : Theory and experiment

The second law of thermodynamics is considered one of the central laws of science, engineering and technology. For over a century it has been assumed to be inviolable by the scientific community. Over the last 10-20 years, however, more than two dozen challenges to it have appeared in the physical literature - more than during any other period in its 150-year history. The number and variety of these represent a cogent threat to its absolute status. This is the first book to document and critique these modern challenges. Written by two leading exponents of this rapidly emerging field, it covers the theoretical and experimental aspects of principal challenges. In addition, unresolved foundational issues concerning entropy and the second law are explored. This book should be of interest to anyone whose work or research is touched by the second law.

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Challenges in Language Testing Around the World : Insights for language test users

This book combines insights from language assessment literacy and critical language testing through critical analyses and research about challenges in language assessment around the world. It investigates problematic practices in language testing which are relevant to language test users such as language program directors, testing centers, and language teachers, as well as teachers-in-training in Graduate Diploma and Master of Arts in Applied Linguistics programs. These issues involve aspects of language testing such as test development, test administration, scoring, and interpretation/use of test results.

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