الصفحة 11
الصفحة 11
Targeted metallo-drugs : Design, development, and mode of action
Inspired by the clinical success of cisplatin as a leading anticancer drug but mindful of the shortcomings associated with its use including dose-limiting toxic side effects and acquired or intrinsic drug resistance, scientists across the globe have been endeavoring to identify new metallo-drugs for therapeutic exploitation. This has led to innovative metallo-drug candidates that (i) enhance cancer cell selectivity, thus reducing toxic side effects, and/or (ii) possess new modes of action to improve efficacy and also target resistance pathways. This and more are captured in MILS- 24 which consists of 12 comprehensive, well-illustrated, and up to date chapters with over 1600 citations, 100 figures, and 10 tables with key contributions from 32 international experts from Europe, Asia, and North and South America. MILS- 24 not only keeps the scientific community abreast of latest developments, it also serves as an invaluable resource to stimulate further research on targeted metallo-drug design and development.
Tablet press machine supervision with scada
As technology is advancing and the needs for development in various fields become necessary, the idea of our project is born, which aspire to develop and automate a press tablet machine. The rotary tablet press machine is designed to produce tablets and capsules in different size and shape and is used widely in pharmacy and chemical industries. Quality control test for tablets depends on several parameters such as compression force, humidity and temperature. The project purpose is to add some features such us reading and saving those parameters to be used in researches and experiments for the research and development laboratory in Arab International University’s faculty of pharmacy.
Systems, software and services process improvement ; 27th European Conference, EuroSPI 2020, Düsseldorf, Germany, September 9–11, 2020, Proceedings
This volume constitutes the refereed proceedings of the 27th European Conference on Systems, Software and Services Process Improvement, EuroSPI conference, held in Düsseldorf, Germany, in September 2020*. The 50 full papers and 13 short papers presented were carefully reviewed and selected from 100 submissions. They are organized in topical sections on visionary papers, SPI manifesto and improvement strategies, SPI and emerging software and systems engineering paradigms, SPI and standards and safety and security norms, SPI and team performance & agile & innovation, SPI and agile, emerging software engineering paradigms, digitalisation of industry, infrastructure and e-mobility, good and bad practices in improvement, functional safety and cybersecurity, experiences with agile and lean, standards and assessment models, recent innovations, virtual reality.
Systematic Design for Emergence in Cellular Nonlinear Networks : With Applications in Natural Computing and Signal Processing
Cellular nonlinear networks are naturally inspired computing architectures where complex dynamic behaviors may emerge as a result of the local or prescribed connectivity among simple cells. Functionally, much like in biology, each cell is defined by a few bits of information called a gene. This book proposes a systematic framework for measuring emergence and a systematic design method to locate computationally meaningful genes in a reasonable computing time. Programs and application examples are provided so that the reader may easily understand the new concepts and develop her own specific experiments. An accessible language recommends it to a large audience including specialists from various interdisciplinary fields who may benefit from a better understanding of emergence and its applications to their specific field.
System Software Reliability
Computer software reliability has never been more important. Today, computers are employed in areas as diverse as air traffic control, nuclear reactors, aircraft, real-time military, industrial process control, security system control, biometric scan-systems, automotive, mechanical and safety control, and hospital patient monitoring systems. Many of these applications require critical functionality as software applications increase in size and complexity. System Software Reliability is an introduction to software reliability engineering as well as a detailed survey of the state-of-the-art techniques, methodologies and tools used to assess the reliability of software and combined software-hardware systems. The most recent research results in the field are reported and future directions in the subject are signposted.
Symptoms in the Pharmacy : A Guide to the Management of Common Illnesses ; 8th ed.
Provides pharmacists working in the community with the treatment information they need when they need it. Each chapter incorporates a decision-making framework which distills the information necessary for treatment along with suggestions on “when to refer” set off in summary boxes. Elucidating case studies are provided throughout, in which pharmacists and doctors describe, in their own words, listening to and treating patients suffering with a range of common problems, from migraine to eczema to IBS. The indispensable guide to assessing and managing common symptoms seen in the pharmacy / Includes information about medicines recently reclassified for OTC supply such as those for malaria prophylaxis and erectile dysfunction / Now includes more highlights of “Red Flag” signs and symptoms / Covers respiratory, gastrointestinal, skin, ear and eye, cardiovascular, and pain conditions / Offers specific recommendations for women’s, men’s and children’s health problems / Provides decision making support for cases involving ethical dilemmas / Features a visual display of relevant treatment guidelines / Emphasizes the evidence base for OTC medicines
Symplectic 4-Manifolds and Algebraic Surfaces : Lectures given at the C.I.M.E. Summer School held in Cetraro, Italy September 2–10, 2003
Modern approaches to the study of symplectic 4-manifolds and algebraic surfaces combine a wide range of techniques and sources of inspiration. Gauge theory, symplectic geometry, pseudoholomorphic curves, singularity theory, moduli spaces, braid groups, monodromy, in addition to classical topology and algebraic geometry, combine to make this one of the most vibrant and active areas of research in mathematics. It is our hope that the five lectures of the present volume given at the C.I.M.E. Summer School held in Cetraro, Italy, September 2-10, 2003 will be useful to people working in related areas of mathematics and will become standard references on these topics.
Symmetry Rules : How Science and Nature are founded on Symmetry
When we use science to describe and understand the world around us, we are in essence grasping nature through symmetry. In fact, modern theoretical physics suggests that symmetry is a, if not the, foundational principle of nature. Emphasizing the concepts, this book leads the reader coherently and comprehensively into the fertile field of symmetry and its applications. Among the most important applications considered are the fundamental forces of nature and the Universe. It is shown that the Universe cannot possess exact symmetry, which is a principle of fundamental significance. Curie's principle - which states that the symmetry of the effect is at least that of the cause - features prominently. An introduction to group theory, the mathematical language of symmetry, is included. This book will convince all interested readers of the importance of symmetry in science. Furthermore, it will serve as valuable background reading for all students in the physical sciences.
Swida hospital : Hospital building
تصميم مشفى في محافظة السويداء ضمن المنطقة الزلزالية الثالثة. يتالف المشروع من أربعة كتل: الكتلة الأولى والثانية تحتويان قبوين يتضمنون ملجأ في الكتلة الأولى و كراج سيارات في كلتا الكتلتين بارتفاع 3.6 امتار و 10 طابق فوق الارض بارتفاع 3.6 امتار في الكتلتين أما الكتلتين الثالثة والرابعة تحتويان قبوين يتضمنون المستودعات و مرآب لسيارات الإسعاف و3 طوابق فوق الأرض بارتفاع موحد لكل الطوابق 3.6 متر المسقط الافقي للمبنى غير منتظم حيث تنقص المساحة الافقية للمسقط ويحدث عدة تراجعات في الطوابق العليا.
Swarm Robotics ; 2nd SAB 2006 International Workshop, Rome, Italy, September 30-October 1, 2006 Revised Selected Papers
Swarm robotics is the study of how large numbers of relatively simple physically embodied agentscanbe designedsuchthat a desiredcollectivebehavioremerges from the local interactions among agents and between the agents and the en- ronment. Swarm robotics has emerged as a novel approach to the coordination of large numbers of robots and is inspired from observation of social insects – ants, termites, wasps and bees – which stand as fascinating examples of how a large number of simple individuals can interact to create collectively intelligent systems. Socialinsects areknownto coordinatetheir actionsto accomplishtasks that are far beyond the capabilities of a single individual: termites build large and complex mounds, army ants organize impressive foraging raids, ants can collectively carry large prey.
Sustainable healthcare architecture
Shows us how critical our green building mission is to the future of human health and secures a lasting legacy that will continue to challenge and focus the green building movement, the healthcare industry, and the world for years to come. Includes: 55 new project case studies, including comparisons of key sustainability indicators for general and specialty hospitals, sub-acute and ambulatory care facilities, and mixed-use buildings. New and updated guest contributor essays spanning a range of health-focused sustainable design topics. Evolving research on the value proposition for sustainable healthcare buildings. Profiles of five leading healthcare systems and their unique sustainability journeys, including the UK National Health Service, Kaiser Permanente, Partners HealthCare, Providence Health & Services, and Gundersen Health System. Focus on the intersection of healthcare, resilience, and a health promotion imperative in the face of extreme weather events. Comparison of healthcare facility-focused green building rating systems from around the world
Sustainable architectural design : An overview
A guide to a sustainable design process that moves from theory, to site and energy use, to building systems, and finally to evaluation and case studies, so you can integrate design and technology for effective sustainable building. Kuppaswamy Iyengar shows you how to get it right the first time, use free energy systems, and utilise technologies that minimize fossil fuel use. Each chapter has a sustainable design overview, technical details and strategies marked by clear sections, a summary, and further resources. Heavily illustrated with charts, tables, drawings, photographs, and case studies, the book shows technologies and concepts integrated into cohesive project types, from small and large office spaces to single and multiuse residences, hospitals, schools, restaurants, and warehouses to demonstrate implementing your designs to meet clients' needs now and for the future.
Sustainability, Human Well-Being, and the Future of Education
Explores the key dimensions of a future education system designed to enable individuals, schools, and communities to achieve the twin twenty-first century challenges of sustainability and human well-being. For much of the twentieth century, Western education systems prepared students to enter the workforce, contribute to society and succeed in relatively predictable contexts. Today, people are at the controls of the planet—making decisions that are dramatically reshaping social, economic, and environmental systems at a global scale.The chapter authors explore various aspects of learning and education system design through the lenses of sustainability and human well-being to evaluate how our understanding and practice of education must transform.
Survie des patients atteints de cancer en France = Survival of cancer patients in France
The Francim network brings together all the French cancer registries. It has set up an observatory for cancerous pathologies in France, the purpose of which is to provide the community with epidemiological indicators useful for the knowledge and management of this pathology, in conjunction with various institutional partners. A first output of this observatory was to provide estimates of the incidence of cancer in France in 2000. Its second output is reported in this work, and concerns the survival of cancer patients, as it could be estimated. from all cancer cases recorded from 1989 to 1997 in 20 French departmental registers. To achieve these objectives, the network joined forces with the biostatistics service of the civil hospices of Lyon, which provided statistical analysis of the data collected by the various registers. The procedures that have been put in place for the different phases of this work can be implemented on a regular basis, for subsequent estimates. They also lend themselves to the implementation of more in-depth studies that are necessary for certain cancers. These so-called “population” data usefully complement the results of studies carried out in the field of clinical research. An additional tool for epidemiological cancer surveillance is therefore now available in France, thanks to the support of the National Cancer League.
Surgical Neuroangiography ; Vol.3 : Clinical and Interventional Aspects in Children
Covers neurovascular diseases in neonates, infants, and children and details the clinical challenges involved in managing lesions of the brain, spinal cord, spine, and head and neck in the pediatric age group. It also places emphasis on the specificities of the perinatal and infancy period.
Surgery of Spinal Tumors
Prior to the era of microneu- surgery, I was firmly involved in the surgery of spinal lesions, and achieved surgical removal of spinal arteriovenous malformations (AVMs).These have been published in a preliminary paper only, for I was unable to accomplish completion of the planned Volume V in my Microneurosurgery series within an adequate time frame. I therefore admire the achievement of Klekamp and Samii, who present to us a most comprehensive work. This monograph is outstanding in many aspects, providing an overview of the clinical experiences gained in a single neurological institution
Surface Effects in Magnetic Nanoparticles
The book is aimed to provide an overview of progress in the understanding of surface properties and surface driven effects in magnetic nanoparticles through recent results of different modelling, simulation and experimental investigations. Its intended audience is Ph.D. students and researchers in materials science. Magnetic nanoparticles have been the subject of continuous and growing interest, from both fundamental and technological points of view, in the last 50 years, since the pionering work of Louis Niel. Nanoparticles are unique physical objects with remarkable magnetic properties which differ greatly from their parent massive materials. They are due to finite size effects of the magnetic core, related to the reduced number of spins cooperatively linked within the particle, and to surface and interface effects, related to the lack of coordination for the surface ions, inducing broken exchange bonds which can result in frustration and spin disorder.
Supramolecular Structure and Function 8
An enormous amount of new knowledge on the molecular basis of various biological phenomena has emerged in the rapidly expanding field of bioscience. Since the frontiers in scientific research are difficult to define‚ the creation of new knowledge depends not only on new methods and concepts but also on interaction with other fields of research. The principles and methods of biophysics should be a rational language for discussion not only between scientists of the different disciplines of natural sciences‚ such as physics‚ mathematics‚ biochemistry‚ molecular biology and biotechnology‚ but also for medicine and social sciences as well.
Superdense QCD Matter and Compact Stars ; Proceedings of the NATO Advanced Research Workshop on Superdense QCD Matter and Compact Stars, Yerevan, Armenia, from 27 September - 4 October 2003.
2 Homogeneous superconducting state 210 3 Superconducting phases with broken space symmetries 213 4 Flavor asymmetric quark condensates 219 5 Concluding remarks 221 Acknowledgments 222 References 223 Neutral Dense Quark Matter 225 Mei Huang and Igor Shovkovy 1 Introduction 225 2 Local charge neutrality: homogeneous phase 226 3 Global charge neutrality: mixed phase 234 4 Conclusion 238 References 238 Possibility of color magnetic superconductivity 241 Toshitaka Tatsumi, Tomoyuki Maruyama, and Eiji Nakano 1 Introduction 241 2 What is ferromagnetism in quark matter? 243 3 Color magnetic superconductivity 248 4 Chiral symmetry and magnetism 253 5 Summary and Concluding remarks 258 Acknowledgments 260 References 260 Magnetic Fields of Compact Stars with Superconducting Quark Cores 263 David M. Sedrakian, David Blaschke, and Karen M. Shahabasyan 1 Introduction 263 2 Free Energy 265 3 Ginzburg-Landau equations 267 4 Vortex Structure 269 5 Solution of Ginzburg-Landau Equations 271 6 The Magnetic Field Components 273 7 Summary 275 Acknowledgments 275 References 275 Thermal Color-superconducting Fluctuations in Dense Quark Matter 277 D. N.
Suites de Sturm, indice de Maslov et périodicité de Bott = Sturm sequences, Maslov index and Bott periodicity
The classical theory of Sturm sequences provides an algorithm to determine the number of roots of a polynomial with real coefficients contained in a given interval. The main object of this thesis is to show that an adequate generalization of the theory of Sturm sequences provides among other things: a notion of Maslov index for an algebraic loop of Lagrangians defined on a commutative ring ; a proof of the fundamental theorem of Hermitian (algebraic) K-theory, theorem due to M. Karoubi ; a proof of Bott's periodicity theorems (topological), in the spirit of the work of F. Latour ; a symplectic-linear computation of the relative group K2 for all commutative rings, in the spirit of the work of R. Sharpe. The book is as far as possible "self-contained" and elementary: it essentially implements linear or bilinear algebra arguments. It presents a unified approach to the Maslov index in terms of Sturm sequences and quadratic forms.
