الصفحة 11
الصفحة 11
Ferroptosis : Methods and protocols
A comprehensive collection of experimental protocols for investigating ferroptosis in different systems, including cultured cells, animal models, and human tissues. The techniques covered in this book look at various aspects of ferroptosis ranging from the detection of lipid peroxidation to the measurement of glutathione peroxidase activity and the evaluation of mitochondrial morphology. Chapters also discuss basic molecular biology methods such as quantitative PCR and immunoblotting, and advanced imaging techniques such as transmission electron microscopy and confocal fluorescence microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Ferro- and Antiferroelectricity : Order/Disorder versus Displacive
Solid-state systems are frequently classi?ed according to their physical, str- tural or chemical properties. Such schemes are extremely helpful since pr- erties related to any such classi?cation are typically known and facilitate id- tifying solids with special material classes. The best-known examples of these schemes are conductivity or resistivity measurements by means of which m- als are easily distinguishable from insulators. However, frequently clear-cut decisions between material classes are not possible, since anisotropy, chemical composition, binding forces and local effects wash out distinct properties and lead to competition or coexistence. Such unresolved situations are especially typical for transition metal oxides that exhibit a variety of ground-state properties in a fascinating way.
Fault Diagnosis and Tolerance in Cryptography ; 3rd International Workshop, FDTC 2006, Yokohama, Japan, October 10, 2006, Proceedings
The sophistication of the underlying cryptographic algorithms, the high complexity of the implementations, and the easy access and low cost of cryptographic devices resulted in increased concerns regarding the reliability and security of crypto-devices. The effectiveness of side channel attacks on cryptographic devices, like timing and power-based attacks, has been known for some time. Several recent investigations have demonstrated the need to develop methodologies and techniques for designing robust cryptographic systems (both hardware and software) to protect them against both accidental faults and maliciously injected faults with the purpose of extracting the secret key. This trend has been particularly motivated by the fact that the equipment needed to carry out a successful side channel attack based on fault injection is easily accessible at a relatively low cost (for example, laser beam technology), and that the skills needed to use it are quite common.
Extreme Financial Risks : From Dependence to Risk Management
Portfolio analysis and optimization, together with the associated risk assessment and management, require knowledge of the likely distributions of returns at different time scales and insights into the nature and properties of dependences between the different assets. This book offers an original and thorough treatment of these two domains, focusing mainly on the concepts and tools that remain valid for large and extreme price moves. Strong emphasis is placed on the theory of copulas and their empirical testing and calibration, because they offer intrinsic and complete measures of dependences.
Extreme Events in Nature and Society
Significant, and usually unwelcome, surprises, such as floods, financial crisis, epileptic seizures, or material rupture, are the topics of Extreme Events in Nature and Society. The book, authored by foremost experts in these fields, reveals unifying and distinguishing features of extreme events, including problems of understanding and modelling their origin, spatial and temporal extension, and potential impact. The chapters converge towards the difficult problem of anticipation: forecasting the event and proposing measures to moderate or prevent it. Extreme Events in Nature and Society will interest not only specialists, but also the general reader eager to learn how the multifaceted field of extreme events can be viewed as a coherent whole.
Explorations in Mathematical Physics : The Concepts Behind an Elegant Language
This book takes you on a tour of the main ideas forming the language of modern mathematical physics. Here you will meet novel approaches to concepts such as determinants and geometry, wave function evolution, statistics, signal processing, and three-dimensional rotations. You'll see how the accelerated frames of special relativity tell us about gravity. On the journey, you'll discover how tensor notation relates to vector calculus, how differential geometry is built on intuitive concepts, and how variational calculus leads to field theory. You will meet quantum measurement theory, along with Green functions and the art of complex integration, and finally general relativity and cosmology.
Experimenting with Dynamic Macromodels : Growth and Cycles
This book presents a macroeconomic dynamic model à la Solow-Swan, including the market for labour, in a discrete time structure. Labour supply is modelled as a reversed S curve (derived in the appendix). The models are expanded to include expenditure on R&D (thus endogenous technical progress), and public expenditure on infrastructures. For each of the three models, numerical simulations are implemented in MAPLE, and the results are shown in time series figures, which make it easy to detect that even small changes in the parameters produce responses in the time behaviour of the main variables: from steady growth, to regular cycles, to chaotic-like time paths. The simulations show that cycles do not promote material welfare, as measured by total undiscounted consumption along the time horizon, and that the comparative action of R&D versus public expenditure is strictly linked to the values assigned to the parameters.
Exercise-induced acute renal failure : Acute renal failure with severe loin pain and Patchy renal Ischemia after anaerobic exercise
Acute renal failure induced by rhabdomyolysis after strenuous, prolonged exercise such as marathon running or mountain climbing is a well-known medical phenomenon, but exercise-induced acute renal failure after short-term anaerobic exercise - for instance, short-distance track races - has been recognized only recently. This monograph provides in-depth information on exercise-induced acute renal failure after short-term anaerobic exercise, which causes severe pain in the loin and patchy renal ischemia with no sign of rhabdomyolysis. Half of the patients suffering from this condition experience renal hypouricemia, for which approximately 20% are treated with dialysis. This book includes characteristics of the disease, diagnosis, treatment and prognosis, and corresponding preventive measures. Important information on gene analysis and etiology is also included, creating a valuable resource for nephrologists as well as for emergency physicians and those in the field of sports medicine.
Eutrophication in the Baltic Sea : Present Situation, Nutrient Transport Processes, Remedial Strategies
This book takes a holistic process-based ecosystem perspective on the eutrophication in the Baltic Sea, with a focus on the factors regulating how the system would respond to changes in nutrient loading. This includes a very special process for the Baltic Sea: land uplift. After being depressed by the glacial ice, the land is now slowly rising adding vast amounts of previously deposited nutrients and clay particles to the system.
European Large Lakes Ecosystem changes and their ecological and socioeconomic impacts
Large lakes offer socio-economic benefits and can be used in many ways, and are often areas in which economic, cultural and political interests overlap. In this book the problems regarding the present status of European large lakes and the directions of change are discussed. Threats caused by direct human impact and by climate change, protection needs and restoration measures are considered.
Estimation of Willingness-to-Pay : Theory, Measurement, Application
To determine the willingness-to-pay (WTP) for products and/or services from a customer perspective is crucial for modern approaches to pricing.With the Price Estimation scene (PE scene) Christoph Breidert introduces a new method to estimate WTP. It works as an additional interview scene appended to conjoint analysis and offers the respondents a dynamically generated sequence of product choices with assigned prices.
Essential Infectious Disease Topics for Primary Care
This book provides an easy-to-use, practical, yet comprehensive resource for family practitioners to use in the daily struggle against infectious diseases. It discusses vaccines and preventive measures as well as information on how to reduce the incidence of antimicrobial-resistant organisms by judiciously prescribing antibiotics and informing patients about the appropriate use of these agents.
Ergodic Dynamics : From Basic Theory to Applications
This textbook provides a broad introduction to the fields of dynamical systems and ergodic theory. Motivated by examples throughout, the author offers readers an approachable entry-point to the dynamics of ergodic systems. Modern and classical applications complement the theory on topics ranging from financial fraud to virus dynamics, offering numerous avenues for further inquiry. Starting with several simple examples of dynamical systems, the book begins by establishing the basics of measurable dynamical systems, attractors, and the ergodic theorems. From here, chapters are modular and can be selected according to interest. Highlights include the Perron–Frobenius theorem, which is presented with proof and applications that include Google PageRank. An in-depth exploration of invariant measures includes ratio sets and type III measurable dynamical systems using the von Neumann factor classification. Topological and measure theoretic entropy are illustrated and compared in detail, with an algorithmic application of entropy used to study the papillomavirus genome. A chapter on complex dynamics introduces Julia sets and proves their ergodicity for certain maps. Cellular automata are explored as a series of case studies in one and two dimensions, including Conway’s Game of Life and latent infections of HIV. Other chapters discuss mixing properties, shift spaces, and toral automorphisms.
EQ-5D value sets
For various reasons, cost benefit analysis is usually rejected in favour of cost-effectiveness or cost-utility analyses, often involving the estimation of the incremental cost per Quality Adjusted Life Year (QALY) gained (Drummond et al, 2005). The estimation of QALYs gained requires valuations for all relevant health states on a scale anchored at 1 = Full health and 0 = Dead. The EQ-5D is widely used in this context and a number of value sets are available for all the health states generated by the EQ-5D descriptive system. These can be readily applied to health outcomes measured as EQ-5D profiles. EQ-5D has become one of the valuation approaches recommended by several reimbursement authorities and academic bodies in European countries
Environmental Risk Assessment : Quantitative Measures, Anthropogenic Influences, Human Impact
The world is a dirty place and getting dirtier all the time. The reasons for this ever-increasing lack of cleanliness are not hard to find, being basically caused by the actions of the six billion people who inhabit the planet. The needs of the people for air, water, food, housing, clothing, heating, materials, oil, gas, minerals, metals, chemicals, and so forth have, over the centuries, given rise to a variety of environmental problems that have been exacerbated or been newly created by the industrialization of the world, the increase in population, and the increase in longevity of the population. The costs of cleaning even fractions of the known environmental problems are truly enormous, as detailed in the volume Environmental Risk Analysis (I. Lerche and E. Paleologos, 2001, McGraw-Hill). The chances of causing new environmental problems, and their associated costs of clean up, are equally challenging in terms of anthropogenic influences and also of the natural environmental problems that can be triggered by humanity.
Environmental Health in Central and Eastern Europe
Complex chemical mixtures impact our health every day. In the United States, and also in Central and Eastern Europe, there are a number of locations where complex chemical mixtures have been released to environmental media. Although exposure to mixtures is common, minimal information exists to quantify these exposures, or to determine their impact on human or ecological receptors. These proceedings present some of the most current research conducted to quantify complex mixtures in the environment and investigate their potential impact on human health. Many of the manuscripts reported in these proceedings represent the most up-to-date measurements of population exposures in Central and Eastern Europe. These studies are of value to health and environmental professionals around the world as they develop strategies for assessing exposures, remediating contaminated environments, and improving public health.
Environmental Effects of Marine Finfish Aquaculture
Environmental risks associated with large-scale marine finfish cage aquaculture have led to claims that the long-term sustainability of the industry is in doubt. Methods and models currently used to measure near and far-field environmental effects of finfish mariculture and to assess their implications for management are presented in 20 chapters arranged in four sections (Eutrophication, Sedimentation and Benthic Impacts, Changes in Trophic Structure and Function, and Managing Environmental Risks). Case studies show how models may be used to predict environmental changes and provide management tools to minimize potentially adverse environmental risks. The volume is of interest to those working towards sustainable development of mariculture, including environmental managers and decision-makers with regulatory responsibilities.
Entertainment computing – ICEC 2007 ; 6th International Conference, Shanghai, China, September 15-17, 2007, Proceedings
This book are organized in topical sections on augmented, virtual and mixed reality, computer games, image processing, mesh and modeling, digital storytelling and interactive systems, sound, music and creative environments, video processing, rendering, computer animation and networks, game based interfaces, as well as robots and cyber pets.
Enhancing Cognitive Assistance Systems with Inertial Measurement Units
The primary goal of this book is the specification, design and testing of an inertially stabilized camera platform for assistance systems with the focus on adaptive inertial measurement.
Engineering and health in compressed air work : Proceedings of the 2nd International conference on engineering and health in compressed air Work held at St Catherine's College, Oxford, from 25th to 27th September, 2002
Presents the proceedings of theSecond International Conference on Engineering and Health in Compressed Air Work, Heald at St Catherine's College, Oxford from 25th to 27th September 2002. The 35 papers in this volume cover a range of subjects, including experience with oxygen decompressionnin the UK and research related tothe introduction of oxygen decompression, which will be of interest to everyone involved with the engineering, medical or regulatory aspects of compressed air working and all those with an interest in hyperbaric exposure.
