الصفحة 11
الصفحة 11
Multi-Scale Approaches in Drug Discovery : From Empirical Knowledge to In silico Experiments and Back
Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents.
Multi-processor system-on-chip 1 : Architectures
covers the key components of MPSoC: processors, memory, interconnect and interfaces. It describes advance features of these components and technologies to build efficient MPSoC architectures. All the main components are detailed: use of memory and their technology, communication support and consistency, and specific processor architectures for general purposes or for dedicated applications.
Multiple-Aspect Analysis of Semantic Trajectories ; First International Workshop, MASTER 2019, Held in Conjunction with ECML-PKDD 2019, Würzburg, Germany, September 16, 2019, Proceedings
This book constitutes the refereed post-conference proceedings of the First International Workshop on Multiple-Aspect Analysis of Semantic Trajectories, MASTER 2019, held in conjunction with the 19th European Conference on Machine Learning and Knowledge Discovery in Databases, ECML PKDD 2019, in Würzburg, Germany, in September 2019.
Multiple Abstraction Hierachies for Mobile Robot Operation in Large Environments
This book focuses on the efficient performance of mobile robots through the use of multi-hierarchical symbolic representations of the environment. A mobile robot intended to perform deliberative actions must possess some symbolic representation of its workspace, but such representations of real environments usually become so large that should be conveniently arranged in order to facilitate and, in some cases, make possible their use. This book addresses all these issues considering symbolic multi-hierarchical structures. Such structures, based on the concept of abstraction, allow a robot to speed up its operation in large environments. Practical solutions tested on real robots (for instance, a robotic wheelchair for elder people) are provided.
Multiphase Reacting Flows : Modelling and Simulation
This book entitled ''Multiphase reacting flows: modelling and simulation'' contains the lecture notes of the CISM (International Centre for Mechanical Sciences) course held in Udine, Italy, on July 3-7, 2006, and it describes various modelling approaches for dealing with polydisperse multiphase reacting flows. A multiphase reacting system is characterized by the presence of multiple phases and in this book we focus on disperse multiphase systems, where one phase can be considered as a continuum, whereas the additional phases are dispersed in the continuous one. In other words, in this book we deal with multiphase systems constituted by particles, droplets or bubbles (i.e., solid particles suspended in a continuous liquid phase, liquid droplets in a gaseous phase, or gas bubbles in liquid.) The other important characteristic elements of the systems discussed in this book are the presence of one or more chemical reactions and the turbulent nature of the flow. The chemical reactions usually involve all the phases present in the system and might be responsible for the formation or disappearance of the disperse and/or continuous phases.
Multi-Objective Evolutionary Algorithms for Knowledge Discovery from Databases
The present volume provides a collection of seven articles containing new and high quality research results demonstrating the significance of Multi-objective Evolutionary Algorithms (MOEA) for data mining tasks in Knowledge Discovery from Databases (KDD). These articles are written by leading experts around the world. It is shown how the different MOEAs can be utilized, both in individual and integrated manner, in various ways to efficiently mine data from large databases.
Multiobjective Evolutionary Algorithms and Applications
Multiobjective Evolutionary Algorithms and Applications provides comprehensive treatment on the design of multiobjective evolutionary algorithms and their applications in domains covering areas such as control and scheduling. Emphasizing both the theoretical developments and the practical implementation of multiobjective evolutionary algorithms, a profound mathematical knowledge is not required. Written for a wide readership, engineers, researchers, senior undergraduates and graduate students interested in the field of evolutionary algorithms and multiobjective optimization with some basic knowledge of evolutionary computation will find this book a useful addition to their book case.
Multinational Enterprises, Foreign Direct Investment and Growth in Africa : South African Perspectives
How can Africa, the world’s most lagging region, benefit from globalisation and achieve sustained economic growth? Africa needs greater investment by Multinational Enterprises (MNEs) to improve competitiveness and generate more growth through positive spill-over effects. Despite the fact that Africa’s returns on investment averaged 29% since 1990, Africa has gained merely 1% of global Foreign Direct Investment (FDI) flows. The challenge for African countries is how to be a more desirable destination for FDI. The study integrates three currents of economic research, namely from the literature on (endogenous) economic growth, convergence and regional integration, the explanations for Africa’s poor growth and the growing understanding of the role of MNEs in a global economy. The empirical side of the book is based on an econometric study of the determinants of FDI in Africa as well as a detailed firm-level survey conducted in 2000.
Multimodality in architecture : Collaboration, technology and education
Examines multimodality in architecture and its impacts on collaborative, technical and educational processes or systems. Multimodality is becoming increasingly critical in contemporary architectural practice and education. Creative design teams face new challenges when they embrace new modes of communication, technology, and knowledge development processes. From diverse online modes of communication to shared digital environments, generative AI and advanced hardware solutions, new modes of information creation, sharing, and application are changing the ways architects and designers work. The book presents new research which empowers international researchers and designers to work more effectively in a diverse range of digital environments. Whether the readers are architects, teachers, students, or scholars, this book provides critical insights and practical tools for understanding and optimising processes in architecture and design.
Multimodal Video Characterization and Summarization
Multimodal Video Characterization and Summarization is a valuable research tool for both professionals and academicians working in the video field. This book describes the methodology for using multimodal audio, image, and text technology to characterize video content. This new and groundbreaking science has led to many advances in video understanding, such as the development of a video summary. Applications and methodology for creating video summaries are described, as well as user-studies for evaluation and testing.
Multimodal User Interfaces : From Signals to Interaction
The book presents a common theoretical framework for fusion and fission of multimodal information using the most advanced signal processing algorithms constrained by HCI rules, described in detail and integrated in the context of a common distributed software platform for easy and efficient development and usability assessment of multimodal tools. The book also demonstrates the use of the multimodal framework for the development of a set of applications in the areas of edutainment, interfaces for disabled people and interfaces for medical applications.
Multimodal Texts in Disciplinary Education : A Comprehensive Framework
This book provides an introduction to multimodality and the role of multimodal texts in today’s education. Presenting a comprehensive framework for analysing and working with multimodal texts in disciplinary education, it serves as a tool for researchers and teachers alike. The second part of the book focuses on sample analyses of a variety of educational texts for different age groups and from different disciplines, including games and online resources. The authors also comment on the specific challenges of each text, and how teachers can discuss such texts with their students to enhance both their understanding of the content and their multimodal literacy.
Multimodal Intelligent Information Presentation
Intelligent Multimodal Information Presentation relates to the ability of a computer system to automatically produce interactive information presentations, taking into account the specifics about the user, such as needs, interests and knowledge, and engaging in a collaborative interaction that helps the retrieval of relevant information and its understanding on the part of the user.The volume includes descriptions of some of the most representative recent works on Intelligent Information Presentation and a view of the challenges ahead.
Multimedia Semantics : The Role of Metadata
This book gives an overview on fundamental issues within the field of multimedia metadata focusing on contextualized, ubiquitous, accessible and interoperable services on a higher semantic level. The book in hand provides a selection of basic articles being a base for multimedia metadata research. Furthermore it presents a view on the current state of the art in multimedia metadata research.
Multimedia Database Retrieval : A Human-Centered Approach
Multimedia Database Retrieval: A Human-Centered Approach presents the latest development in user-centered methods and the state-of-the-art in visual media retrieval. It includes discussion on perceptually inspired non-linear paradigm in user-controlled interactive retrieval (UCIR) systems. It also features a coherent approach which focuses on specific topics within content/concept-based retrievals via audio-visual information modeling of multimedia. Highlights include: * Exploring an adaptive machine that can learn from its environment * Optimizing the learning system by incorporating self-organizing adaptation into the retrieval process * Demonstrating state-of-the-art applications within small, medium, and large databases
Multimedia Data Mining and Knowledge Discovery
Multimedia Data Mining and Knowledge Discovery provides an overview of the current state-of-the-art in the field of multimedia data mining and knowledge discovery, and discusses the variety of hot topics in multimedia data mining research. Consisting of an introductory section and four topical parts, the book describes the objectives and current tendencies in multimedia data mining research and their applications.
Multimedia big data computing for IoT applications : Concepts, paradigms and solutions
This book considers all aspects of managing the complexity of Multimedia Big Data Computing (MMBD) for IoT applications and develops a comprehensive taxonomy. It also discusses a process model that addresses a number of research challenges associated with MMBD, such as scalability, accessibility, reliability, heterogeneity, and Quality of Service (QoS) requirements, presenting case studies to demonstrate its application. Further, the book examines the layered architecture of MMBD computing and compares the life cycle of both big data and MMBD. Written by leading experts, it also includes numerous solved examples, technical descriptions, scenarios, procedures, and algorithms.
Multilevel Synthesis : From the Group to the Individual
This book presents a historical panorama of the evolution of demographic thought from its eighteenth-century origins up to the present day, and uses it to demonstrate how the multilevel approach can resolve some of the contradictions that have become apparent and achieve a synthesis of the different approaches employed. Part one guides the reader from period analysis to multilevel analysis, examining longitudinal and event history analysis on the way. Part two is a detailed account of multilevel analysis, its methods, and the relevant mathematical models notably as regards the type of variables being used. Numerous examples, examined across successive sections, make the book clear and easy to follow.
Multigenic and Induced Systemic Resistance in Plants
This comprehensive volume consists of a series of up-to-date reviews, each incorporating current models and knowledge related to mechanisms of resistance either expressed constitutively or induced systemically in plants. Each chapter covers a topic related to the phenomenon of plant resistance to fungal and bacterial pathogens, insects, nematodes, viruses or abiotic stress in plants, as well as the application of this knowledge to protect crops now and in the future. Researchers, upper-level undergraduate and graduate students, and those teaching courses in plant physiology, entomology and plant pathology will find this volume a much needed asset.
Multifield Problems in Solid and Fluid Mechanics
This book summarizes the main scientific results of the Collaborative Research Center on Multifield Problems in Continuum Mechanics. The book is divided into three main sections: A: Volume-Coupled Problems, devoted to fields which are coupled inside the processing domain or volume, B: Boundary-Coupled Problems, here physical fields and processes are coupled via domain boundaries, C: Fundamental Methods, search into the mathematical concepts and backgrounds of multifield and multiscale modeling.
