الصفحة 11
الصفحة 11
DNA Methylation : Development, Genetic Disease and Cancer
It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many fields of biology and medicine such as developmental biology, genetic imprinting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems.
Dissecting the Molecular Anatomy of Tissue
The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.
Disorders of the Oral Cavity
The oral cavity is the part of the mouth behind the teeth and the gums surrounded by the soft palate, which is the movable layer hanging from the back of the hard palate and ending in the nasal cavity and under the tongue and the mucous membrane connecting it with the inner part of the jaw. It forms the first part of the digestive system. It is considered the entrance of food and drink into the digestive system and an entrance to the air into the respiratory system and it contains the teeth through which the chewing process begins, and on the tongue, which plays a fundamental role in the process of taste and swallowing and is also used by humans in speech to communicate with others, and animals use it to make sounds.
Diseases of the Pancreas : Current Surgical Therapy
"Diseases of the Pancreas" is based on the latest comprehensive data about molecular mechanism of acute pancreatitis, chronic pancreatitis and pancreatic cancer. The diagnostic techniques including histology, radiology, sonography etc.
Diseases of the Heart, Chest & Breast : Diagnostic Imaging and Interventional Techniques
This book deals with imaging of diseases of heart, chest and breast. These fields have substantially advanced during the last few years, driven by both clinical developments and advances in imaging technology.لإheir chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As a result, this book presents a comprehensive review of current knowledge in imaging of the heart and chest , as well as thoracic interventions and a selection of "hot topics" of breast imaging.
Dipeptidyl Aminopeptidases : Basic Science and Clinical Applications
Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in the field will contribute to this book, which will present a state-of-the-art view on these enzymes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent. The sections of the book will focus on various topics including DP IV and related enzymes in: expression and function, metabolic disorders, immune mechanisms and immune disorders, neuronal diseases and cancer, and related drug development.
Digital Mammography ; 8th International Workshop, IWDM 2006, Manchester, UK, June 18-21, 2006, Proceedings
This volume of Springer’s Lecture Notes in Computer Science series records th the proceedings of the 8 International Workshop on Digital Mammography (IWDM), which was held in Manchester, UK, June 18–21, 2006. The meetings bringtogetheradiversesetofresearchers(physicists,mathematicians,computer scientists, engineers), clinicians (radiologists, surgeons) and representatives of industry, who are jointly committed to developing technology, not just for its ownsake,but to supportclinicians inthe earlydetection andsubsequentpatient management of breast cancer.
Difficult Decisions in Thoracic Surgery : An Evidence-Based Approach
Brief chapters are devoted to a specific question or decision in general thoracic surgery that is difficult or controversial. Although some of the content may be available in major thoracic texts, rarely are such questions posed specifically and analyzed according to the level of supporting evidence available. This book is unique in aiming to address the issues in the most clear and informed manner possible; the chapters contain both evidence-based recommendations and descriptions of surgeons’ personal practices based on their experience and the published literature. Chapters are organized around clearly identified recommendations. This provides uniformity to the presentations, making possible the identification of useful material at a glance. A general introduction describes evidence-based data and their use, decision analytic models, and how both physicians and patients make decisions currently. Over 50 different topics are then presented, including a review of available evidence and a general discussion of recommended practice.
Diagnostic Nuclear Medicine
The present text, supplemented with many detailed and informative illustrations, represents an adjunct to the standard knowledge of diagnostic nuclear medicine and provides both the student and the professional with an overview of developments during the past decade.
Diagnostic Imaging in Head and Neck Cancer
This succinct compendium focuses on the key practical aspects of head and neck cancer imaging. It also provides essential information on handling and analyzing imaging data. Head and neck cancer is the sixth most common cancer worldwide. CT and MRI imaging are absolutely crucial to accurate diagnosis and staging, and radiologists have to be especially familiar with the anatomy of that region of the body. In addition, they must be highly proficient in interpreting radiographic images in order to judge the patterns of metastasis, response to treatment, and the signs and patterns of recurrence. This concise but detailed book describes the latest imaging modalities for all types of head and neck cancer diagnosis in light of recent technological advances. Featuring abundant high-quality images supplemented by advice from experts on the management of each cancer, it is a valuable resource for diagnostic and general radiologists, as well as all medical staff involved in the management of head and neck cancers.
Diagnosis of Aging Skin Diseases
Diagnosis of Aging Skin Diseases provides the clinician with an encyclopedia of geriatric dermatoses that can be used on rounds or in a reference environment. It provides a structured illustrated review of the various lesions encountered, which will make this an invaluable reference resource for all physicians dealing with older skin.
Developmental Biology of Neoplastic Growth
In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest.
Development of breast cancer therapy and gender
Breast cancer is a disease in which abnormal cells in the breast tissues multiply and form an invasive (or malignant) tumor. Such tumors can invade and damage the tissue around them and spread to other parts of the body through the lymphatic or vascular systems. We will describe in our study several types of breast cancer, since they are classified into two main categories: “invasive” and “non-invasive,” or in situ. While invasive cancer has spread from the breast ducts or glands to other parts of the breast, non-invasive cancer has not spread from the original tissue. Our study will focus on the best tests that examine the breasts which are used to detect and diagnose breast cancer: Physical exam and health history, Clinical breast exam (CBE), Mammogram, Ultrasound exam, MRI (magnetic resonance imaging), Blood chemistry studies and Biopsy. We will include the value of such tests after breast cancer has been diagnosed, to find out if cancer cells have spread within the breast or to other parts of the body.
Dermatoethics : Contemporary ethics and professionalism in dermatology
This extensively updated textbook reviews the ethical issues faced within dermatology. Bringing together practical real-life case scenarios and scholarly analysis, it covers the foundations of bioethics, as well as ethical issues associated with the various roles dermatologists play, including clinician, professional, educator, business person, and scholar. New chapters on the ethics of dermatologic care during pandemics, non-traditional interventions, private equity in dermatology, self-care and improvement, skin cancer screening, maintenance of certification, the ethics of clinical trial design are also included.
Dépistage et cancers cutanés = Skin cancer screening
This work takes stock of the epidemiological aspects of these tumors in France and their clinical aspects. It offers an identification of risk markers and predisposing lesions specific to each tumor type. A strategy for the early diagnosis of carcinoma on the one hand and of melanoma on the other is proposed, relying, in particular for melanoma, on the new methods of care offered today to the patient.
Deoxynucleoside Analogs in Cancer Therapy
Emerging as an important new volume in the renowned Cancer Drug Discovery and Development™ series, Deoxynucleoside Analogs in Cancer Therapy expertly summarizes the current status of development and application of deoxynucleoside analogs. Authoritative up-to-date reviews are presented by scientists well known in their specific areas and all contributions include valuable sound advice on structure and topics. Organized into several sections, the first part covers general aspects of drug uptake and metabolism and explains how novel technology has enabled a rapid expansion of this field. The second part is concerned with a number of specific drugs including cytarabine, gemcitabine, troxacitabine, clofarabine and Ara-G. The final section covers pharmacokinetics, prodrugs, and specific applications such as radiosensitization, gene therapy, and the use of deoxynucleoside analogs as tracers
Dental biomaterials: from fundamental principles to clinical applications
Novel approaches are being developed to prevent and treat prevalent oral diseases like dental caries, periodontitis, and oral cancer. Researchers are also exploring the potential of biomaterials in regenerative dentistry, such as promoting bone growth and repairing damaged oral tissues.The ongoing research and development in dental materials and biomaterials holds great promise for improving oral health outcomes. However, it is imperative to maintain a sustained focus on research to fully leverage their potential and effectively address the existing gaps in dental care.In the special issue titled "Dental Biomaterials: From Fundamental Principles to Clinical Applications," significant findings have emerged from a variety of sources, including in vitro experiments and clinical trials.
Dendritic Cells in Clinics
Great advances have taken place in basic research and the clinical usefulness of dendritic cells (DCs). It has now been clearly established, for instance, that these cells play a crucial role in immune responses against infectious diseases and cancers. Antigen-presenting DCs are widely distributed in the body and regulate both immunity and immune tolerance. Experimental studies have provided important insights into DCs and how they can be used for treating animal models of various diseases that occur in humans. The role of these cells in pathogenesis and the treatment of human diseases is elaborately set forth in this valuable book. Researchers in the field are optimistic that DCs, already in use for treating patients with cancers, soon can be used therapeutically for patients with chronic infections, autoimmune diseases, and allergic manifestations. This volume provides a working definition of DCs and also explains the phenotypes and functions of DCs so that these can be readily understood not only by clinicians but by immunologists, researchers, and students as well.
Deep Learning and its Applications
Presents an introduction to deep learning and various applications of deep learning such as recommendation systems, text recognition, diabetic retinopathy prediction of breast cancer, prediction of epilepsy, sentiment, fake news detection, software defect prediction and protein function prediction.
David Paul von Hansemann : Contributions to Oncology : Context, Comments and Translations
Presents translations of all the relevant German texts, and analyses the background and context of Hansemann's theories as well as the reasons why he was almost completely forgotten. It shows that some of Hansemann’s ideas may still be relevant to cancer research today, and that he deserves to be remembered in relation to cancer as Vordenker unter den führenden Denkern seiner Zeit - The foremost of the leading thinkers of his time.
