الصفحة 103
الصفحة 103
Alzheimers Disease : Advances in genetics, molecular and cellular biology
Alzheimer’s Disease: Advances in Genetics, Cellular and Molecular Biology provides exciting, comprehensive and up-to-date summaries of the most important recent advances in the genetic, molecular, biochemical, and cell biological studies of AD. The studies and advances described in this volume will help to accelerate the process of rational drug discovery and soon serve to extend and enhance the mental health and lifespan of our burgeoning elderly population.
Alzheimers Disease
Alzheimer’s disease (AD) is a neurodegenerative disease that robs the minds of our elderly population. Approximately one in every eight adults over the age of 65 and nearly half of those over 85 are afflicted with this disease. The aging population in developed societies will impose an ever increasing socioeconomic threat in the future. Current medicines for AD patients are mainly symptomatic treatments and a huge unmet medical need exists to slow the progression of this disease. A great deal of research has been dedicated to understanding the pathogenesis of AD from which comes many ideas for intervening with its progression. Some of these ideas have been fast-tracked to clinical trials due to the availability of medicines with proven clinical efficacies for other diseases (e.g. atorvastatin, simvastatin, rosiglitazone and clioquinol) while others represent novel chemical entities (e.g. glycogen synthase kinase-3 inhibitors).
Alzheimer : 100 Years and Beyond
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4th, 1906 in Tübingen. The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiative of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, at the very site of the original lecture, namely the Institute of Psychiatry at the University of Tübingen in Germany from November 2nd to 5th, 2006, was the highlight of the Alzheimer Year. Over the last century of Alzheimer research (1906-2006), remarkable progress has been achieved. Most of the authors of the major discoveries and the people involved in research in this field will present, during the meeting and in this volume, the pioneering research explaining the conditions under which they were conducted. The goal of this book is to honor the work accomplished, to summarize the most important knowledge and to provide material for the history of science.
Alvar Aalto Houses
Finnish architect and designer Alvar Aalto (1898-1976) designed nearly one hundred single-family houses. Aalto, who is also known for his furniture and glassware, worked in a unique style that blended modernism and traditional vernacular architecture. Authors Jari and Sirkkaliisa Jetsonen (Finnish Summer Houses) present twenty-six of Aalto's innovative residences—from small summer homes and postwar standardized housing to large housing complexes for industrial commissions—built between the 1920s to the 1960s.
Alternatives to Animal Testing : Proceedings of Asian Congress 2016
This book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs.
Alternative medicines for diabetes management : Advances in pharmacognosy and medicinal chemistry
Apart from diet and exercise, the strategic use of different classes of prescribed or non-prescribed xenobiotic compounds for the restoration of euglycemic levels in the body is well known. The ongoing rivalry between the recommended usage of allopathic medicines versus ayurvedic remedies has encouraged many researchers to focus their studies on thoroughly isolating and characterizing the extracts from different parts of plants and then evaluating their relative activities via in vitro, in vivo and in some cases clinical studies.
Alternative concrete - geopolymer concrete : Emerging research and opportunities
Focuses on fly ash-based alkali-activated geopolymer concrete, its production and characteristic properties. The re-use of waste materials and industrial by-products, such as fly ash, is not only economically of interest but also helps to reduce carbon dioxide emissions. The carbon footprint of these materials is much lower than that of concrete using ordinary Portland cement. They thus offer new sustainable solutions to the construction industry.
Alternative breast imaging : Four model-based approaches
Medical imaging has been transformed over the past 30 years by the advent of computerized tomography (CT), magnetic resonance imaging (MRI), and various advances in x-ray and ultrasonic techniques. An enabling force behind this progress has been the (so far) exponentially increasing power of computers, which has made it practical to explore fundamentally new approaches. In particular, what our group terms "model-based" modalities-which produce tissue property images from data using nonlinear, iterative numerical modeling techniques-have become increasingly feasible. Alternative Breast Imaging: Four Model-Based Approaches explores our research on four such modalities, particularly with regard to imaging of the breast: (1) MR elastography (MRE), (2) electrical impedance spectroscopy (EIS), (3) microwave imaging spectroscopy (MIS), and (4) near infrared spectroscopic imaging (NIS).
Allergic rhinitis
Allergic rhinitis is a very common disorder that affects people of all ages, peaking in the teenage years. It is frequently ignored, underdiagnosed, misdiagnosed, and mistreated, which not only is detrimental to health but also has societal costs. Although allergic rhinitis is not a serious illness, it is clinically relevant because it underlies many complications, is a major risk factor for poor asthma control, and affects quality of life and productivity at work or school. Management of allergic rhinitis is best when directed by guidelines. A diagnostic trial of a pharmacotherapeutic agent could be started in people with clinically identified allergic rhinitis; however, to confirm the diagnosis, specific IgE reactivity needs to be recorded.
Alicyclobacillus : Thermophilic Acidophilic Bacilli
Soft drinks with pHs lower than 4. 0 are subjected to minimum pasteuri- tion at 65 °C for 10 min as required by the Japanese Food Sanitation Law. Not only pathogenic bacteria but most spore-forming bacteria are unable to grow at this low pH condition, and thus reports of microbial spoilage in pasteurized acidic soft drinks are rare. Since 1982, when the spoilage of aseptically packed apple juice was - tributed to a new type of acidophilic spore-forming bacteria in Germany, a succession of similar complaints regarding other fruit juice concentrates and their products has been received. In the beginning, the bacteria were classified in the genus Bacillus, but later, in 1992, the new genus Ali- clobacillus was proposed owing to their characteristic cellular membranes containing omega-alicyclic fatty acids. A group of Alicyclobacillus strains, responsible for the tainting of fruit juices, was then described as A. a- doterrestris in 1999. They are acidophilic and grow preferably at around pH 4. 0. They are thermophilic and grow better at temperatures above 40 °C. This indicates that we might have been missing them by our or- nary methods of bacterial detection at pH 7. 0 and 35 °C.
Algorithms in Bioinformatics ; Vol.4175 : 6th International Workshop, WABI 2006, Zurich, Switzerland, September 11-13, 2006, Proceedings
This book constitutes the refereed proceedings of the 6th International Workshop on Algorithms in Bioinformatics, WABI 2006, held in Zurich, Switzerland in September 2006 in the course of the ALGO 2006 conference meetings. The 36 revised full papers presented were carefully reviewed and selected from 100 submissions. All current issues of algorithms in bioinformatics are addressed, ranging from mathematical tools to experimental studies of approximation algorithms and reports on significant computational analyses. Numerous biological problems are dealt with, including genetic mapping, sequence alignment and sequence analysis, phylogeny, comparative genomics, and protein structure. For the first time also machine-learning approaches along with combinatorial optimization are covered.
Algorithms in Bioinformatics ; 8th International Workshop, WABI 2008, Karlsruhe, Germany, September 15-19, 2008. Proceedings
This book constitutes the refereed proceedings of the 8th International Workshop on Algorithms in Bioinformatics, WABI 2008, held in Karlsruhe, Germany, in September 2008 as part of the ALGO 2008 meeting.
Algorithms and data structures ; 9th international workshop, WADS 2005, Waterloo, Canada, August 15-17, 2005, Proceedings
The papers in this volume were presented at the 9th Workshop on Algorithmsand Data Structures (WADS 2005). at the University of Waterloo, Waterloo, Canada. The workshopalternates with the Scandinavian Workshop on Algorithm Theory (SWAT), con-tinuing the tradition of SWAT and WADS starting with SWAT 1988 and WADS1989. From 90 submissions, the Program Committee selected 37 papers for pre-sentation at the workshop. includ Algorithm Analysis and Problem Complexity Data Structures Discrete Mathematics in Computer Science Computer Graphics Numeric Computing
Algorithms and data structures ; 17th International Symposium, WADS 2021, Virtual Event, August 9–11, 2021, Proceedings
This book constitutes the refereed proceedings of the 17th International Symposium on Algorithms and Data Structures, WADS 2021, held in virtually in August 2021. The 47 full papers, presented together with two invited lectures, were carefully reviewed and selected from a total of 123 submissions. They present original research on the theory, design and application of algorithms and data structures.
Algorithms and computation ; Vol. 4288: 17th International symposium, ISAAC 2006, Kolkata, India, December 18-20, 2006, Proceedings
This book constitutes the refereed proceedings of the 17th International Symposium on Algorithms and Computation, ISAAC 2006, held in Kolkata, India in December 2006. The 73 revised full papers presented were carefully reviewed and selected from 255 submissions. The papers are organized in topical sections on algorithms and data structures, online algorithms, approximation algorithm, graphs, computational geometry, computational complexity, network, optimization and biology, combinatorial optimization and quantum computing, as well as distributed computing and cryptography.
Algorithms and computation ; Vol. 3827 ; 16th International symposium, ISAAC 2005, Sanya, Hainan, China, December 19-21, 2005, Proceedings
This book constitutes the refereed proceedings of the 16th International Symposium on Algorithms and Computation, ISAAC 2005, held in China in 2005. The 112 revised full papers presented were carefully reviewed and selected from 549 submissions. The papers are organized in topical sections on computational geometry, computational optimization, graph drawing and graph algorithms, computational complexity, approximation algorithms, internet algorithms, quantum computing and cryptography, data structure, computational biology, experimental algorithm mehodologies and online algorithms, randomized algorithms, parallel and distributed algorithms, graph drawing and graph algorithms, computational complexity, combinatorial optimization, computational biology, computational complexity, computational optimization, computational geometry, approximation algorithms, graph drawing and graph algorithms, computational geometry, approximation algorithms, graph drawing and graph algorithms, and data structure.
Algorithms – ESA 2007 ; 15th Annual European Symposium, Eilat, Israel, October 8-10, 2007, Proceedings
This book presented submissions in the engineering and applications track. The papers address all current subjects in algorithmics reaching from design and analysis issues of algorithms over to real-world applicat.
Algorithms – ESA 2005 ; 13th Annual European Symposium, Palma de Mallorca, Spain, October 3-6, 2005, Proceedings
This volume contains the 75 contributed papers and the abstracts of the threeinvited lectures presented at the 13th Annual European Symposium on Algo-rithms (ESA 2005), held in Spain, 2005. respectively.Papers were solicited in all areas of algorithmic research, including but notlimited to algorithmic aspects of networks, approximation and on-line algo-rithms, computational biology, computational geometry, computational financeand algorithmic game theory, data structures, database and information re-trieval, external memory algorithms, graph algorithms, graph drawing, machinelearning, mobile computing, pattern matching and data compression, quantumcomputing, and randomized algorithms. The algorithms could be sequential,distributed, or parallel. Submissions were especially encouraged in the area ofmathematical programming and operations research, including combinatorialoptimization, integer programming, polyhedral combinatorics, and semidefiniteprogramming.Each extended abstract was submitted to one of the two tracks.
Algorithmic learning theory ; Vol.4264 : 17th International Conference, ALT 2006, Barcelona, Spain, October 7-10, 2006, Proceedings
This book constitutes the refereed proceedings of the 17th International Conference on Algorithmic Learning Theory, ALT 2006, held in Barcelona, Spain in October 2006, colocated with the 9th International Conference on Discovery Science, DS 2006.The 24 revised full papers presented together with the abstracts of five invited papers were carefully reviewed and selected from 53 submissions. The papers are dedicated to the theoretical foundations of machine learning.
Algorithmic learning theory ; Vol. 3734 ; 16th international conference, ALT 2005, Singapore, October 8-11, 2005, Proceedings
This volume contains the papers presented at the 16th Annual InternationalConference on Algorithmic Learning Theory (ALT 2005), which was held (Republic of Singapore), 2005. The main objective of theconference is to provide an interdisciplinary forum for the discussion of the the-oretical foundations of machine learning as well as their relevance to practicalapplications. The volume includes 30 technical contributions, which were selected by theprogram committee from 98 submissions.
