الصفحة 102
الصفحة 102
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Mammalian and Avian Transgenesis : New Approaches

Mammalian and Avian Transgenesis presents a collection of novel methods for the production of a wide range of transgenic animals. The manual focuses largely on mice, but also contains protocols for successful transgenesis in rats, cows, pigs and birds. The manual provides detailed, step-by-step protocols covering all aspects of the production of transgenic animals, including the use of lentiviral vectors in gene transfer, intracytoplasmic sperm injection, nuclear transfer, large insert transgenesis, conditional gene expression systems, the use of reporter genes in transgenesis and transgenesis in large animals and birds. The text is supplemented by superb color photos. While the focus is on newly established techniques, the fundamental methods of transgenesis are also covered for those new to the field. Thus this manual is perfectly suited for those wishing to adopt new technologies in transgenesis.

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Malliavin Calculus for Lévy Processes with Applications to Finance

While the original works on Malliavin calculus aimed to study the smoothness of densities of solutions to stochastic differential equations, this book has another goal. It portrays the most important and innovative applications in stochastic control and finance, such as hedging in complete and incomplete markets, optimisation in the presence of asymmetric information and also pricing and sensitivity analysis. In a self-contained fashion, both the Malliavin calculus with respect to Brownian motion and general Lévy type of noise are treated. Besides, forward integration is included and indeed extended to general Lévy processes. The forward integration is a recent development within anticipative stochastic calculus that, together with the Malliavin calculus, provides new methods for the study of insider trading problems.

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Malignant Mesothelioma : Pathogenesis, Diagnosis, and Translational Therapies

(Review from JAMA) Malignant mesothelioma is an uncommon neoplasm usually associated with exposure to asbestos. Because of its low incidence, thorough reviews of the topic are hard to find. Harvey Pass and colleagues have edited an up-to-date, comprehensive book that includes a wide range of information, from a historical perspective to descriptions of the latest treatment. The authors . . . have written chapters on the carcinogenesis, molecular genetics, and clinical aspects of mesothelioma. Malignant Mesothelioma is suitable for a broad audience. Laboratory researchers will use it as a resource for information about the pathogenesis, animal models, molecular genetics, and cell lines of mesothelioma. . . . Clinicians will benefit from this complete guide to the presentation, prognosis, imaging, and treatment of the disease. I highly recommend this book to all who are interested in mesothelioma.

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Malaria: Drugs, Disease and Post-genomic Biology

This volume brings some of the worlds best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two. The opening chapters discuss antimalarials and resistance to them in Africa and Asia. Then there are reviews of the different clinical manifestations of malaria, ranging from uncomplicated infections to severe disease and its complications.

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Malaria : Genetic and Evolutionary Aspects

This book was originally conceived at a conference at the University of Turin in Italy. The conference was organized to examine the so-called “Malaria Hypothesis”, that is to say, the higher fitness of t- lassemia heterozygotes in a malarial environment, and to pay tribute to the proponent of that hypothesis, J.B.S. Haldane. Contributors to this book examine certain genetic and evolutionary aspects of malaria which is a major killer of human populations, especially in Africa and Asia. There were attempts to discredit Haldane’s contribution from two directions: (a) it has been suggested that the “Malaria Hypothesis” was known long before Haldane and that there was nothing original about his idea (Lederberg 1999), and that (b) the hypothesis of heterozygote su- riority was first suggested by the Italian biologist Giuseppe Montalenti who communicated his idea to Haldane (Allison 2004).

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Making Healthcare Safe : The Story of the Patient Safety Movement

This unique and engaging open access title provides a compelling and ground-breaking account of the patient safety movement in the United States, told from the perspective of one of its most prominent leaders, and arguably the movement’s founder, Lucian L. Leape, MD. Covering the growth of the field from the late 1980s to 2015, Dr. Leape details the developments, actors, organizations, research, and policy-making activities that marked the evolution and major advances of patient safety in this time span. In addition, and perhaps most importantly, this book not only comprehensively details how and why human and systems errors too often occur in the process of providing health care, it also promotes an in-depth understanding of the principles and practices of patient safety, including how they were influenced by today’s modern safety sciences and systems theory and design. Indeed, the book emphasizes how the growing awareness of systems-design thinking and the self-education and commitment to improving patient safety, by not only Dr. Leape but a wide range of other clinicians and health executives from both the private and public sectors, all converged to drive forward the patient safety movement in the US.

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Making Fisheries Management Work : Implementation of Policies for Sustainable Fishing

This book seeks to widen the perspective taken on implementation in fisheries management. The cases presented in this volume addresses legal, administrative, and political challenges regarding implementation of resource conservation policies. The book addresses problems relating to goal achievement, but also causes of deliberate change of political goals during implementation. Fisheries management systems are embedded in inert social structures and natural conditions that vary among different states. Consequently, the book takes a historical and comparative approach, describing the historical developments of national implementation systems and the conditions that shaped their development. It thus seeks to explain why national fisheries management systems have evolved differently, focusing on Norwegian, Faeroese, and EU/Danish management systems. The descriptive and explanatory outlines are accompanied by qualitative assessments of the systems effectiveness as tools for collective action.

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Making Beautiful Deep-Sky Images : Astrophotography with Affordable Equipment and Software

Professor Greg Parker's astronomical photographs are widely known for their excellence, and a selection of them has recently been shown as a public exhibition in the UK. In Making Beautiful Deep-Sky Images, he provides a detailed account of how spectacular deep-sky images can be taken by amateur astronomers using CCD cameras, and how they can subsequently be processed and enhanced in the "electronic darkroom" for maximum beauty and impact. Quite simply, this is a "how to do it" book for people who want to make stunning astronomical pictures.

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Make and Test Projects in Engineering Design : Creativity, Engagement and Learning

This is a book about the invention and testing of ideas. By describing how to generate engaging problem situations for engineering students to solve it inspires original currents of thought. This is the first book that formalises an important aspect of early learning in engineering design.

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Magnetism and Accelerator-Based Light Sources : Proceedings of the 7th International School ‘‘Synchrotron Radiation and Magnetism’’, Mittelwihr (France), 2018

Collects the contributions of the seventh school on Magnetism and Synchrotron Radiation held in Mittelwihr, France, from 7 to 12 October 2018. It starts with an introduction to the physics of modern X-ray sources followed by a general overview of magnetism.

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Magnetism : From Fundamentals to Nanoscale Dynamics

Gives an comprehensive account of magnetism, spanning the historical development, the physical foundations and the continuing research underlying the field, one of the oldest yet still vibrant field of physics. It covers both the classical and quantum mechanical aspects of magnetism and novel experimental techniques. Perhaps uniquely, it also discusses spin transport and magnetization dynamics phenomena associated with atomically and spin engineered nano-structures against the backdrop of spintronics and magnetic storage and memory applications.

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Magnetism : A Synchrotron Radiation Approach

Contains the edited lectures of the fourth Mittelwihr school on "Magnetism and Synchrotron Radiation". This series of events introduces graduate students and nonspecialists from related disciplines to the field of magnetism and magnetic materials with emphasis on synchrotron radiation as an experimental tool of investigation. These lecture notes present in particular the state of the art regarding the analysis of magnetic properties of new materials.

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Magnetic Resonance of Myelination and Myelin Disorders

The book has been extensively revised and expanded to do justice to the rapid advances in MR technology, molecular biochemistry, and genetics and the discovery of new disease entities with prominent white matter involvement. Forty chapters have been added, and the number of illustrations has risen considerably. The ability to confirm the presence of genetic alterations in a number of disorders allows more advantageous presentation of the phenotypic variation as expressed in differ.

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Magnetic Resonance Imaging in Orthopedic Sports Medicine

Though magnetic resonance imaging has helped revolutionize the field of orthopedic medicine, a difference in perspective persists between radiology and orthopedic specialists. Magnetic Resonance Imaging in Orthopedic Sports Medicine is an interdisciplinary resource designed to bridge this gap.

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Magnetic Resonance Imaging in Ischemic Stroke

The imaging of stroke has undergone significant changes owing to the rapid progress in imaging technology. This volume, comprising three parts, is designed to provide a comprehensive summary of the current role of MR imaging in patients with ischemic stroke. The first part outlines the clinical presentations of stroke and discusses the diagnostic efficacy and therapeutic impact of MR imaging. The second and third parts form the core of the volume, and are based on a novel approach in that the topic is presented from two very different viewpoints. Part 2 provides a detailed presentation of the distinguishing features of stroke from the radiologist's perspective. By contrast, part 3 addresses the needs of the clinician, documenting specific stroke syndromes and their correlates on MR imaging. The overall aim has been to create a well-illustrated volume with broad appeal that links pathology, radiology and stroke medicine in an informative manner.

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Magnetic Nanostructures in Modern Technology ; Spintronics, Magnetic MEMS and Recording

A team of outstanding scientists in the field of modern magnetic nanotechnologies illustrates the state of the art in several areas of advanced magneto-electronic devices, magnetic micro-electromechanical systems and high density information storage technologies.The physics and chemistry of nano-scale systems have made rapid advances and there are real prospects of translating exciting scientific findings into a new generation of processes and high technology products with a potential impact on several industrial sectors. In particular the development of nano-structured magnetic materials plays a leading role in the increasing miniaturization of devices with superior performances.

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Magnetic Nanostructures

Addresses the exciting and rapidly developing topic of nanostructured magnetic materials. It combines modern topics in nanoscale magnetism with issues relating to the fabrication and characterization of magnetic nanostructures. The chapters describe a wide range of physical aspects, together with theoretical and experimental methods. "Magnetic Nanostructures" will be of interest to researchers and specialists both in academic and industrial research. Graduate students will also find in this book an accessible introduction to the essential issues.

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Magnetic Monopoles

This monograph addresses the field theoretical aspects of magnetic monopoles. Written for graduate students as well as researchers, the author demonstrates the interplay between mathematics and physics. He delves into details as necessary and develops many techniques that find applications in modern theoretical physics. This introduction to the basic ideas used for the description and construction of monopoles is also the first coherent presentation of the concept of magnetic monopoles. It arises in many different contexts in modern theoretical physics, from classical mechanics and electrodynamics to multidimensional branes. The book summarizes the present status of the theory and gives an extensive but carefully selected bibliography on the subject. The first part deals with the Dirac monopole, followed in part two by the monopole in non-abelian gauge theories. The third part is devoted to monopoles in supersymmetric Yang-Mills theories.

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Magnetic Microscopy of Nanostructures

Contains a comprehensive collection of overview articles on novel microscopy methods for imaging magnetic structures on the nanoscale. Written by leading scientists in the field the book covers synchrotron based methods, spin polarized electron methods, and scanning probe techniques. It will be a valuable source of reference for graduate students and newcomers to the field.

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Magnetic Heterostructures : Advances and Perspectives in Spinstructures and Spintransport

Magnetic heterostructures constitute an important field in magnetism and nanotechnology, which has developed over the past fifteen years due to important advances in epitaxial- growth techniques and lithographic processes. Magnetic heterostructures combine different physical properties which do not exist in nature. Examples are semiconductors/ferromagnets, superconductors/ferromagnets, and ferromagnets/antiferromagnets. These combinations display rich and novel physical properties different from those that exit in any single one of them. Interlayer exchange coupling, exchange bias, proximity effects, giant magneto-resistance, tunneling magneto-resistance, spininjection and spintransport are examples of new physical phenomena that rely on the combination of different materials layers

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