الصفحة 10
الصفحة 10
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Drug target selection and validation

Focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.

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DNA barcoding : Methods and protocols

Covers the latest advancements and methods used to study DNA barcoding. The chapters in this book are organized into six parts: theory, DNA manipulation, specialized barcoding methods, analysis of DNA barcodes, completing a successful DNA barcode project, and barcoding as citizen science. Part One looks at several theoretical issues in DNA barcoding concerned with DNA barcodes that can and should be used. Part Two discusses protocols for processing samples into DNA barcodes, including DNA isolation, sequencing and managing samples, and the resulting DNA barcodes. Part Three explores the next generation of DNA barcoding such as FRET-based detection, dual nanopore detection, skimming, and closed-tube methods. Part Four addresses programs and websites that handle DNA barcoding data, and includes character-based approaches, barcode gap methods, integrated approaches, and Barcode of Life Database

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Distributed, High-Performance and Grid Computing in Computational Biology ; International Workshop, GCCB 2006, International Workshop, GCCB 2006, Eilat, Israel, January 21, 2007, Proceedings

Modern computational biology and bioinformatics are characterized by large and complex structured data and by applications requiring considerable computing resources, such as processing units, storage elements and software programs. In addition, these disciplines are intrinsically geographically distributed in terms of their instruments, communities and computing resources. Tackling the computational challenges in computational biology and bioinformatics increasingly requires high-end and distributed computing infrastructures, systems and tools.

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Distributed network systems : From concepts to implementations

This textbook covers both theoretical and practical aspects of distributed computing. It describes the client-server model for developing distributed network systems, the communication paradigms used in a distributed network system, and the principles of reliability and security in the design of distributed network systems. Based on theoretical introductions, the book presents various implementation strategies and techniques for building distributed network systems, including examples in TCP/IP communications, the use of remote procedure call and remote method invocation techniques, and the development of web-based applications, distributed databases, and mobile computing systems.

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Distributed computing and internet technology ; 17th International Conference, ICDCIT 2021, Bhubaneswar, India, January 7–10, 2021, Proceedings

This book constitutes the proceedings of the 17th International Conference on Distributed Computing and Internet Technology, ICDCIT 2020, held in Bhubaneswar, India, in January 2021. The 13 full papers presented together with 4 short papers were carefully reviewed and selected from 99 submissions. The papers were organized in topical sections named: invited talks, cloud computing and networks, distributed algorithms, concurrency and parallelism, graph algorithms and security, social networks and machine learning, and short papers.

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Distributed computing ; Vol. 4167 ; 20th International Symposium, DISC 2006, Stockholm, Sweden, September 18-20, 2006, Proceedings

DISC, the International Symposium on DIStributed Computing, is an annual forum for presentation of research on all facets of distributed computing, inc- ding the theory, design, analysis, implementation, and application of distributed systems and networks. The 20th anniversary edition of DISC was held on S- tember 18-20, 2006, in Stockholm, Sweden. There were 145 extended abstracts submitted to DISC this year, and this - lume contains the 35 contributions selected by the Program Committee and one invited paper among these 145 submissions.

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Discovery Science ; 11th International Conference, DS 2008, Budapest, Hungary, October 13-16, 2008. Proceedings

This book constitutes the refereed proceedings of the 11th International Conference on Discovery Science, DS 2008, held in Budapest, Hungary, in October 2008, co-located with the 19th International Conference on Algorithmic Learning Theory, ALT 2008.

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Discovering Knowledge in Data : An Introduction to Data Mining

Provides the tools needed to thrive in today’s big data world. Demonstrates how to leverage a company’s existing databases to increase profits and market share, and carefully explains the most current data science methods and techniques. The reader will “learn data mining by doing data mining”.

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Digital Terrain Modelling : Development and Applications in a Policy Support Environment

This book presents a set of papers on Digital Terrain Modelling for Policy Support which aims to be informative and stimulating for both developers and users of digital terrain models. It should also be useful for professi- als who are interested in the wider aspects of the applications of terrain models in support for policies and decision making. There is an increasing demand for regional and continental scale data for use in environmental modelling and spatial analysis to support envir- mental policy development and implementation. Important environmental processes act at regional and continental scales, for example climatic change inducing floods and soil erosion, and management of these pr- esses for the sustainable development of society requires policies to be - plied at the corresponding scales. One of the most important factors inf- encing these environmental processes which act on the earth’s surface is the surface topography, hence the need for extensive, harmonised digital terrain models.

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Digital Libraries : Universal and Ubiquitous Access to Information ; 11th International Conference on Asian Digital Libraries, ICADL 2008, Bali, Indonesia, December 2-5, 2008. Proceedings

This book constitutes the refereed proceedings of the 11th International Conference on Asian Digital Libraries, ICADL 2008, held in Bali, Indonesia, in December 2008.

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Digital Libraries : The Era of Big Data and Data Science; 16th Italian Research Conference on Digital Libraries, IRCDL 2020, Bari, Italy, January 30–31, 2020, Proceedings

The chapter "Identifying, Classifying and Searching Graphic Symbols in the NOTAE System" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

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Digital Libraries : Research and Development; 1st International DELOS Conference, Pisa, Italy, February 13-14, 2007, Revised Selected Papers

This book presented similarity search, architectures, personalization, interoperability, evaluation, miscellaneous, preservation, video data management, 3D objects, and peer to peer.

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Digital Finance : Security Tokens and Unlocking the Real Potential of Blockchain

In Digital Finance: Security Tokens and Unlocking the Real Potential Blockchain, readers will realize why security tokens are creating huge excitement in the financial industry. By combining the latest in technology and the potential for automated world-class investor protections, regulatory compliance and customer service, security tokens offer a plethora of benefits that will drive cost reductions, enhance flexibility and open up opportunities for new business models and revenue streams. Digital Finance thoroughly examines how this powerful technology can overhaul our current financial infrastructure in a way that will increase efficiency, transparency, and security.

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Developing bus management system for AIU

To solve the problem of congestion in bus stops for students, members of the administrative and educational people at the Arab International University, an application was designed that allows the user to reserve a seat on the bus. The application provides prior reservation and enters the study time for the user, the application reminds him for the time of his going to the university. The basic functions of the application are designed according to the general analysis, The development of the application used Laravel, flutter frameworks, AI and MySQL database processing technology. The application has accomplished such functions as notification for location. The test of the application is running in good conditions. The use of the application will solve the problem of bus crowding. The efficiency of the platform makes it a very good candidate to be implemented for any person in Arab International University.

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Designing big data platforms : How to use, deploy, and maintain big data systems

Provides expert guidance and valuable insights on getting the most out of Big Data systems. Helps readers understand how to process large amounts of data with well-known Linux tools and database solutions, use effective techniques to collect and manage data from multiple sources, transform data into meaningful business insights, and much more. Author Yusuf Aytas, a software engineer with a vast amount of big data experience, discusses the design of the ideal Big Data platform: one that meets the needs of data analysts, data engineers, data scientists, software engineers, and a spectrum of other stakeholders across an organization. Detailed yet accessible chapters cover key topics such as stream data processing, data analytics, data science, data discovery, and data security. This real-world manual for Big Data technologies: Provides up-to-date coverage of the tools currently used in Big Data processing and management / Offers step-by-step guidance on building a data pipeline, from basic scripting to distributed systems / Highlights and explains how data is processed at scale / Includes an introduction to the foundation of a modern data platform

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Design of steel-concrete composite structures using high-strength materials

Design of Steel-Concrete Composite Structures Using High Strength Materials provides guidance on the design of composite steel-concrete structures using combined high-strength concretes and steels. The book includes a database of over 2,500 test results on composite columns to evaluate design methods, and presents calculations to determine critical parameters affecting the strength and ductility of high-strength composite columns. Finally, the book proposes design methods for axial-moment interaction curves in composite columns. This allows a unified approach to the design of columns with normal- and high-strength steel concrete materials.

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Deep Data Analytics for New Product Development

The benefits of reading this book are twofold. The first is an understanding of the stages of a new product development process from ideation through launching and tracking, each supported by information about customers. The second benefit is an understanding of the deep data analytics for extracting that information from data. These analytics, drawn from the statistics, econometrics, market research, and machine learning spaces, are developed in detail and illustrated at each stage of the process with simulated data. The stages of new product development and the supporting deep data analytics at each stage are not presented in isolation of each other, but are presented as a synergistic whole.

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Decrypted Secrets : Methods and Maxims of Cryptology

Cryptology, for millennia a "secret science", is rapidly gaining in practical importance for the protection of communication channels, databases, and software. Beside its role in computerized information systems (public key systems), more and more applications within computer systems and networks are appearing, which also extend to access rights and source file protection. The first part of this book treats secret codes and their uses - cryptography. The second part deals with the process of covertly decrypting a secret code - cryptanaly-sis - where in particular advice on assessing methods is given. The book presupposes only elementary mathematical knowledge.

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Data-Driven Policy Impact Evaluation : How Access to Microdata is Transforming Policy Design

Provides statistical tools for evaluating the effects of public policies advocated by governments and public institutions. Experts from academia, national statistics offices and various research centers present modern econometric methods for an efficient data-driven policy evaluation and monitoring, assess the causal effects of policy measures and report on best practices of successful data management and usage. Topics include data confidentiality, data linkage, and national practices in policy areas such as public health, education and employment. It offers scholars as well as practitioners from public administrations, consultancy firms and nongovernmental organizations insights into counterfactual impact evaluation methods and the potential of data-based policy and program evaluation.

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Databases, Information Systems, and Peer-to-Peer Computing ; International Workshops, DBISP2P 2005/2006, Trondheim, Norway, August 28-29, 2006, Revised Selected Papers

The P2P paradigm lends itself to constructing large-scale, complex, adaptive, autonomous and heterogeneous database and information systems, endowed with clearly specified and difierential capabilities to negotiate, bargain, coordinate and self-organize the information exchanges in large-scale networks. This vision will have a radical impact on the structure of complex organizations (business, sci- tific or otherwise) and on the emergence and the formation of social communities, and on how the information is organized and processed. The P2P information paradigm naturally encompasses static and wireless connectivity and static and mobile architectures. Wireless connectivity combined with the increasingly small and powerful mobile devices and sensors poses new challenges as well as opp- tunities to the database community. Information becomes ubiquitous, highly distributed and accessible anywhere and at any time over highly dynamic, - stable networks with very severe constraints on the information management and processing capabilities.

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