الصفحة 10
الصفحة 10
Biosimilars : Regulatory, clinical, and biopharmaceutical development
Provides a comprehensive overview of the biosimilar regulatory framework, the development process and clinical aspects for development of biosimilars. The development path of a biosimilar is just as unique as a development path of a new drug, tailored by the mechanism of action, the quality of the molecule, published information on the reference product, the current competitive environment, the target market and regulatory guidance, and most importantly, the emerging totality of evidence for the proposed biosimilar during development.
Biopharmaceutical processing : Development, design, and Implementation of manufacturing processes
Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes covers bioprocessing from cell line development to bulk drug substances. The methods and strategies described are essential learning for every scientist, engineer or manager in the biopharmaceutical and vaccines industry. The integrity of the bioprocess ultimately determines the quality of the product in the biotherapeutics arena, and this book covers every stage including all technologies related to downstream purification and upstream processing fields. Economic considerations are included throughout, with recommendations for lowering costs and improving efficiencies.
Biopharmaceutical manufacturing progress, trends and challenges
Source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation.
Bio-Materials & Prototyping Applications in Medicine
Bio-Materials and Prototyping Applications in Medicine focuses on bio-materials and prototyping applications in medical environments. The applications that ardiscussed integrate bio-materials, CAD, and physical prototyping techniques.
Basic methods and protocols on Sourdough
Details traditional and modern approaches to characterize sourdough and to monitor its features during production, propagation and use, through state-of- the art analytical tools. Chapters guide reader through procedures to prepare and propagate the mature sourdough, to analyse and monitor microbiological, biochemical and rheology features of sourdough, sensory, and nutritional attributes of baked goods. Written in the format of the Methods and Protocols in Food Science series, chapters list necessary materials and methods for readily reproducible protocols.
Average-Cost Control of Stochastic Manufacturing Systems
This book is concerned with hierarchical control of manufacturing systems under uncertainty. It focuses on system performance measured in long-run average cost criteria, exploring the relationship between control problems with a discounted cost and that with a long-run average cost in connection with hierarchical control. A new theory is articulated that shows that hierarchical decision making in the context of a goal-seeking manufacturing system can lead to a near optimization of its objective. The approach in the book considers manufacturing systems in which events occur at different time scales.
Automated technology for verification and analysis ; 3rd International Symposium, ATVA 2005, Taipei, Taiwan, October 4-7, 2005, Proceedings
The Automated Technology for Veri?cation and Analysis (ATVA) international symposium series was initiated in 2003, responding to a growing interest in formal veri?cation spurred by the booming IT industry, particularly hardware design and manufacturing in East Asia. Its purpose is to promote research on automated veri?cation and analysis in the region by providing a forum for int- action between the regional and the international research/industrial commu- ties of the ?eld. ATVA 2005, the third of the ATVA series, was held in Taipei, Taiwan, 2005. The main theme of the symposium encompasses - sign, complexities, tools, and applications of automated methods for veri?cation and analysis. This book constitutes the refereed proceedings of the symposium .
Aulton's pharmaceutics : The design and manufacture of medicines
Offers a complete course in one book for students in all years of undergraduate pharmacy and pharmaceutical sciences degrees. Thoroughly revised, updated and extended by experts in their fields and edited by Professors Kevin Taylor and Michael Aulton, this new edition includes the science of formulation, pharmaceutical manufacturing and drug delivery. All aspects of pharmaceutics are covered in a clear and readily accessible way and extensively illustrated throughout, providing an essential companion to the entire pharmaceutics curriculum from day one until the end of the course. Fully updated throughout, with the addition of new chapters, to reflect advances in formulation and drug delivery science, pharmaceutical manufacturing and medicines regulation Designed and written for newcomers to the design and manufacture of dosage forms Relevant pharmaceutical science covered throughout Includes the science of formulation and drug delivery Reflects current practices and future applications of formulation and drug delivery science to small drug molecules, biotechnology products and nanomedicines Key points boxes throughout Over 400 online multiple choice questions
AsiaSim 2007 ; Asia Simulation Conference 2007, Seoul, Korea, October 10-12, 2007, Proceedings
This book contains modeling, simulation, and their applications.It also contains e-business, supply chain management, general and engineering applications, manufacturing, medical, military,networks, transportation, traffic and virtual reality.
Artificial Intelligence for Cloud and Edge Computing
Discusses the future possibilities of AI with cloud computing and edge computing. Aims to conduct analyses, implementation and discussion of many tools (of artificial intelligence, machine learning and deep learning and cloud computing, fog computing, and edge computing including concepts of cyber security) for understanding integration of these technologies. Readers can quickly get an overview of these emerging topics and get many ideas of the future of AI with cloud, edge, and in many other areas. Topics include machine and deep learning techniques for Internet of Things based cloud systems; security, privacy and trust issues in AI based cloud and IoT based cloud systems; AI for smart data storage in cloud-based IoT; blockchain based solutions for AI based cloud and IoT based cloud systems.This book is relevent to researchers, academics, students, and professionals. Presents fusion of cloud computing services and AI technology for bringing a significant change in the technology industry; Includes self-assessment problems for increasing knowledge of real world problems, i.e., how AI and cloud/edge computing can change business for the better; Provides innovative results of integrations of AI in other applications such as healthcare, finance, manufacturing, transportation, agriculture, etc.
Artificial Intelligence and Cybersecurity : Advances and Innovations
Provides advanced system implementation for Smart Cities using artificial intelligence. It addresses the complete functional framework workflow and explores basic and high-level concepts. The book is based on the latest technologies covering major challenges, issues and advances, and discusses intelligent data management and automated systems.
Architecture and design for industry 4.0 : Theory and practice
The book is structured into three sections (research, practice, and technologies), with the goal of creating a new framework useful for widespread awareness necessary to initiate technology transfer processes for the benefit of the public sector, universities, research centers, and innovative companies, and a new professional figure capable of controlling the entire process is essential. Thus, the book chapters arouse a series of relevant topics such as computational and parametric design, performance-based architecture, data-driven design strategies, parametric environmental design and analysis, computational and parametric structural design and analysis
Architectural scale models in the digital age : Design, representation and manufacturing
Complex geometric forms generated using virtual media can be tested and validated only by means of physical models, which also make it possible to assess their practical application. The complexity of contemporary architectural design requires the mastery of new methods of producing scale models, which opens a new chapter in the field of modeling, and is the focus of this book. Along with the traditional methods that provide the basis for modeling, this book presents the principles of digital NURBS modeling, parametric modeling, digital modeling support, and model creation, complete with a number of tutorials, practical advice and examples found in architectural practice today.
Applying the Kaizen in Africa : A New Avenue for Industrial Development
At present, how to develop industries is a burning issue in Africa, where population growth remains high and economic development has thus far failed to provide sufficient jobs for many, especially young people and women. The creation of productive jobs through industrial development ought to be a central issue in steering economic activity across the continent.The authors of this book, consisting of two development economists and five practitioners, argue that the adoption of Kaizen management practices, which originated in Japan and have become widely used by manufacturers in advanced and emerging economies, is decisively the most effective first step for industrial development in Africa.This open access book discusses what Kaizen management is, why it is applicable to Africa, and why it can provide Africa with a springboard for sustainable economic growth and employment generation.
Applied Reliability and Quality : Fundamentals, Methods and Procedures
"Reliability and quality professionals need to know about each other's work activities because this may help them - directly or indirectly - to perform their tasks more effectively. Applied Reliability and Quality: Fundamentals, Methods and Procedures meets the need for a single volume that considers applied areas of both reliability and quality. Before now, there has not been one book that covers both applied reliability and quality; so to gain knowledge of each other's specialties, these people had to study various books, articles, or reports on each area."
Annals of scientific society for assembly, handling and industrial robotics
This proceedings presents a good overview of the current research landscape of industrial robots. The objective of MHI Colloquium is the successful networking at both academic and management level. Thereby, the colloquium focuses an academic exchange at a high level in order to distribute the obtained research results, to determine synergy effects and trends, to connect the actors in person and in conclusion, to strengthen the research field as well as the MHI community. In addition, there is the possibility to become acquatined with the organizing institute. Primary audience is formed by members of the scientific society for assembly, handling and industrial robotics (WGMHI).
ANEMONA : A Mulit-agent Methodology for Holonic Manufacturing Systems
ANEMONA is a multi-agent system (MAS) methodology for holonic manufacturing system (HMS) analysis and design, based on HMS requirements. The development process of ANEMONA provides clear and HMS-specific modeling guidelines for HMS designers, and complete development phases for the HMS life cycle.
Analysis, Control and Optimization of Complex Dynamic Systems
Analysis, Control and Optimization of Complex Dynamic Systems gathers in a single volume a spectrum of complex dynamic systems related papers written by experts in their fields, and strongly representative of current research trends. Complex systems present important challenges, in great part due to their sheer size which makes it difficult to grasp their dynamic behavior, optimize their operations, or study their reliability. Yet, we live in a world where, due to increasing inter-dependencies and networking of systems, complexity has become the norm. With this in mind, the volume comprises two parts. The first part is dedicated to a spectrum of complex problems of decision and control encountered in the area of production and inventory systems. The second part is dedicated to large scale or multi-agent system problems occurring in other areas of engineering such as telecommunication and electric power networks, as well as more generic context.
Analysis and Development of Sustainable Urban Production Systems
Manufacturing of products in urban production sites is connected to unique potentials, yet also to specific challenges. Urban factories can provide functional diversity and contribute positive impacts to a city. The concept of urban production receives rising attention in research and industry and it is recognized in its interdisciplinary nature. With a holistic approach from both the urban perspective and the factory perspective, negative impacts can be minimized, positive effects enabled and mutually beneficial, symbiotic combinations created. The presented framework and methods for the evaluation and implementation of sustainable urban production systems allow the assessment of impacts and provide the means to control and utilize the unique strengths of urban factories for cities and industry. This will allow a structured derivation of methods and measures from the concept of urban production for producing enterprises and the urban stakeholders.
Algorithmic Foundations of Robotics VI
Robot algorithms are abstractions of computational processes that control or reason about motion and perception in the physical world. Because actions in the physical world are subject to physical laws and geometric constraints, the design and analysis of robot algorithms raises a unique combination of questions in control theory, computational and differential geometry, and computer science. Algorithms serve as a unifying theme in the multi-disciplinary field of robotics. This volume consists of selected contributions to the sixth Workshop on the Algorithmic Foundations of Robotics. This is a highly competitive meeting of experts in the field of algorithmic issues related to robotics and automation.
