الصفحة 10
الصفحة 10
Morphometrics with R
The R language and environment offers a single platform to perform a multitude of analyses from the acquisition of data to the production of static and interactive graphs. This offers an ideal environment to analyze shape variation and shape change. This open-source language is accessible for novices and for experienced users. Adopting R gives the user and developer several advantages for performing morphometrics: evolvability, adaptability, interactivity, a single and comprehensive platform, possibility of interfacing with other languages and software, custom analyses, and graphs. The book explains how to use R for morphometrics and provides a series of examples of codes and displays covering approaches ranging from traditional morphometrics to modern statistical shape analysis such as the analysis of landmark data, Thin Plate Splines, and Fourier analysis of outlines.
Moral reasoning at work : Rethinking ethics in organizations ; 2nd ed.
Moral Reasoning at Work offers a fresh perspective on how to live with them using ethics and moral psychology research. It argues that decision-makers must go beyond compliance and traditional approaches to ethics to prepare for moral dilemmas. The book has been updated with a range of examples from the author’s more recent research, to reflect current issues affecting organizations in the digital age. With two new chapters on artificial intelligence and social media, this new edition provides an up-to-date overview of ethical challenges in organizations.
Monte Carlo Methods in Fuzzy Optimization
This book is a concise and readable introduction to Monte Carlo methods to find good approximate solutions to fuzzy optimization problems. Various basic applications and illustrative examples are presented in an understandable way. The aim of the book is to convince the reader that Monte Carlo methods can be useful in generating approximate solutions to fuzzy optimization problems.
Mono-Cycle Photonics and Optical Scanning Tunneling Microscopy : Route to Femtosecond Ångstrom Technology
"Mono-Cycle Photonics and Optical Scanning Tunneling Microscopy" deals with both the ultrashort laser-pulse technology in the few- to mono-cycle region and the laser-surface-controlled scanning-tunneling microscopy (STM) extending into the spatiotemporal extreme technology. The former covers the theory of nonlinear pulse propagation beyond the slowly-varing-envelope approximation, the generation and active chirp compensation of ultrabroadband optical pulses, the amplitude and phase characterization of few- to mono-cycle pulses, and the feedback field control for the mono-cycle-like pulse generation. In addition, the wavelength-multiplex shaping of ultrabroadband pulse is described. The latter covers the CW-laser-excitation STM, the femtosecond-time-resolved STM and atomic-level surface phenomena controlled by femtosecond pulses.
Monoaminergic modulation of cortical excitability
Monoaminergic Modulation of Cortical Excitability serves as an integrative and comprehensive comparison of the diverse and complex modulatory action of dopamine, noradrenaline, and serotonin receptors in the cortex. The volume is organized into several sections offering a broad spectrum of opinions on how the monoamine systems affect cortical function from a cellular/sub-cellular level to a system level. The complexity of these interactions are discussed in light of recent data showing how disruption of these systems dramatically affects the memory formation and information processing in the cortex.
Money, Banking, and Financial Markets : A Modern Introduction to Macroeconomics
Introduction to money, banking, and financial markets, with a special emphasis on the importance of confidence and trust in the macroeconomic system. It also presents the theory of endogenous money creation, in contrast to the standard money multiplier and fractional reserve explanation found in other textbooks. The U.S. economy and financial institutions are used to explain the theoretical and practical framework, with international examples weaved in throughout the text. It covers key topics including monetary policy, fiscal policy, accounting principles, credit creation, central banks, and government treasuries. Additionally, the book considers the international economy, including exchange rates, the Eurozone, Chinese monetary policy, and reserve currencies. Taking a broad look at the financial system, it also looks at banking regulation, cryptocurrencies, real estate, and the oil and gold commodity markets. Students are supported with chapter objectives, key terms, and problems.
Molecular Pathology of Gynecologic Cancer
This book focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. The volume begins with an explication of the editors’ hypothesis that cancer is mainly a disease of the cell cycle, based on the deregulation of the physiological process of cell reproduction. The following eleven chapters focus on specific issues in gynecologic cancers, including: a proposed model of ovarian serous carcinogenesis, molecular markers for ovarian epithelial cancer, an overview of the pathology of endometrial cancer, molecular genetic aspects of endometrial carcinoma and cervical cancer, a natural history of Human Papilloma Virus (HPV) as it relates to cervical cancer, and hereditary issues in gynecologic cancers. The concluding chapter proposes and outlines a holistic approach to the treatment of female cancer patients.
Molecular Neurosurgery with Targeted Toxins
Focuses on the highly successful use of the immunotoxins, 192 IgG-saporin and ME20.4-saporin, to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals. Also discussed are the uses of anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of central nervous system demyelination. Overview perspectives and, in some cases, more practical details are provided that allow the reader to appreciate exactly what is involved in using these agents. Both practical and theoretical, Molecular Neurosurgery With Targeted Toxins provides readers with not only the background to understand these techniques, but also numerous real-life examples that can be readily adapted to new purposes and an ever-increasing number of new targeted toxins.
Molecular Mechanisms of Cancer
Cancer may constitute the most extensively studied functions constitute a second line of defense that disease entity of our time. Nevertheless, our com- protects against transforming defects in oncogenes prehension of the cellular and molecular pathology or tumor-suppressor genes and are here considered of malignant transformation is incomplete.
Molecular Biomethods Handbook
Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. Molecular Biomethods Handbook, 2nd Edition expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Part A of the book describes nucleic acid methods, such as gene expression profiling, microarray analysis and quantitative PCR. In Part B, protein and cell-based methods are outlined, in subjects ranging from protein engineering to high throughput screening. Written by a well-established panel of research scientists, Molecular Biomethods Handbook, 2nd Edition provides an up-to-date collection of methods used regularly in the authors’ own research programs.
Molecular Biology of Human Cancers: An Advanced Student's Textbook
Presents many of the molecules and mechanisms generally important in human cancers. Following an overview on the cancer problem, individual chapters deal with cancer genetics and epigenetics, DNA damage and repair, oncogenes, tumor suppressors, regulatory pathways in cancer, apoptosis, cellular senescence, tumor invasion, and metastasis. A consensus is emerging that while these common mechanisms and molecules are all relevant to human cancers, in each cancer type (or even subtype) a selection of them are extremely important. For selected cancers, the route from genetic and epigenetic changes to their biological and clinical behavior can already be traced. Part II of the book presents a broad, but exemplary selection of cancers that serve as paradigms to illustrate this point. In fact, cancer research has now reached a critical stage, in which the accumulated knowledge on molecular mechanisms is gradually translated into improved prevention, diagnosis, and treatment. The state, pitfalls, and potential of these efforts are summarized in Part III. More than ever, cancer research is now an interdisciplinary effort which requires a basic knowledge of commonly used terms, facts, issues, and concepts. The aim of this book is to provide advanced students and practitioners of different disciplines with this basis, bridging the gap between standard textbooks of molecular biology, pathology, and oncology on the one hand and the specialized cancer literature on the other.
Molecular analysis of B lymphocyte development and activation
The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume.
Modulated Temperature Differential Scanning Calorimetry : Theoretical and Practical Applications in Polymer Characterisation
This book provides both a basic and advanced treatment of the theory of the technique followed by a detailed exposition of its application to reacting systems, blends and semicrystalline polymers by the leaders in all of these fields. It is an essential text for anybody interested in calorimetry or polymer characterization, especially if they have found that conventional DSC cannot help them with their problems.
Modular Algorithms in Symbolic Summation and Symbolic Integration
Brings together two streams in computer algebra: symbolic integration and summation on the one hand, and fast algorithmics on the other hand. In many algorithmically oriented areas of computer science, the analysis of al gorithms placed into the lime light by DonKnuth’stalkat the 1970ICM –provides a crystal-clear criterion for success. The researcher who designs an algorithm that is faster (asymptotically, in the worst case) than any previous method receives instant gratification : her result will be recognized as valuable. Al as, the downside is that such results come along quite infrequently, despite our best efforts. An alternative evaluation method is to run a new algorithm on examples; this has its obvious problems, but is sometimes the best we can do. George Collins, one of the fathers of computer algebra and a great experimenter,wrote in 1969: “I think this demonstrates again that a simple analysis is often more revealing than a ream of empirical data (although both are important). ” Within computer algebra, some areas have traditionally followed the former methodology, notably some parts of polynomial algebra and linear algebra. Other areas, such as polynomial system solving, have not yet been amenable to this - proach. The usual “input size” parameters of computer science seem inadequate, and although some natural “geometric” parameters have been identified (solution dimension, regularity), not all (potential) major progress can be expressed in this framework. Symbolic integration and summation have been in a similar state.
Modernizing the academic teaching and research environment : Methodologies and cases in business research
Constitutes a valuable manual for young and seasoned business researchers alike, and provides a comprehensive summary for the whole research journey. It is a must-read for all researchers who need to understand the basics of business research, from identifying research topics, to planning and organizing the research process, and selecting the most appropriate methodology for the topic at hand. This book also provides insights on how to avoid common pitfalls in business research and outlines the research skills needed to write a fine piece of research. In order to capture the innovative element of research, the book also highlights methods for thinking outside the box. It also stresses the importance of respecting ethics while conducting business research. Lastly, it presents important cases and provides hands-on training for preparing survey tools. Readers looking to master business research won’t want to miss out on this unique and insightful book.
Modern socio-technical perspectives on privacy
This book provides researchers and professionals with a foundational understanding of online privacy as well as insight into the socio-technical privacy issues that are most pertinent to modern information systems, covering several modern topics (e.g., privacy in social media, IoT) and underexplored areas (e.g., privacy accessibility, privacy for vulnerable populations, cross-cultural privacy).
Modern Sliding Mode Control Theory : New Perspectives and Applications
This book is a collection of invited chapters covering several areas of modern sliding mode control theory. The authors identify key contributions defining the theoretical and applicative state of the art of the sliding mode control theory and the most promising trends of the ongoing research activities. The contributions is divided in four main parts: Part I: Basic Theory. Part II: Design Methods. Part III: Observers and Fault Detection. Part IV: Applications.
Modern Portfolio Optimization with NuOPT™, S-PLUS®, and S+Bayes™
This book fills the gap between current university instruction and current industry practice by providing a comprehensive computationally-oriented treatment of modern portfolio optimization and construction methods. The computational aspect of the book is based on extensive use of S-Plus®, the S+NuOPT™ optimization module, the S-Plus Robust Library and the S+Bayes™ Library, along with about 100 S-Plus scripts and some CRSP® sample data sets of stock returns. A special time-limited version of the S-Plus software is available to purchasers of this book.
Modern operating system
incorporates the latest developments and technologies in operating systems (OS) technologies. Author Andy Tanenbaum's clear and entertaining writing style outlines the concepts every OS designer needs to master. In-depth topic coverage includes processes, threads, memory management, file systems, I/O, deadlocks, interface design, multimedia, performance tradeoffs, and trends in OS design. Case studies explore popular OS and provide real-world context. Tanenbaum also provides information on current research based on his expe
Modern Multivariate Statistical Techniques : Regression, Classification, and Manifold Learning
Remarkable advances in computation and data storage and the ready availability of huge data sets have been the keys to the growth of the new disciplines of data mining and machine learning, while the enormous success of the Human Genome Project has opened up the field of bioinformatics. These exciting developments, which led to the introduction of many innovative statistical tools for high-dimensional data analysis, are described here in detail. The author takes a broad perspective; for the first time in a book on multivariate analysis, nonlinear methods are discussed in detail as well as linear methods.
