الصفحة 10
الصفحة 10
Fatty acids
Fatty acid metabolism, including the de novo synthesis, uptake, oxidation, and derivation of fatty acids, plays several important roles at cellular and organ levels. Recent studies have identified characteristic changes in fatty acid metabolism in idiopathic pulmonary fibrosis (IPF) lungs, which implicates its dysregulation in the pathogenesis of this disorder. Here, we review the evidence for how fatty acid metabolism contributes to the development of pulmonary fibrosis, focusing on the profibrotic processes associated with specific types of lung cells, including epithelial cells, macrophages, and fibroblasts. We also summarize the potential therapeutics that target this metabolic pathway in treating IPF.
Fare astronomia con piccoli telescopi = Are astronomy with small telescopes
Giant tools are not necessarily required to produce scientifically valid results in the field of astronomy. Even the amateur with a small telescope, with a diameter of only 8-9 cm, can contribute to the science of the sky by making useful observations of the Sun, the Moon, planets, comets, asteroids, double or variable stars, nebulae and star clusters. The manual of M.K. Gainer explains what the minimum equipment is (a small telescope, a computer, a simple digital camera), how to use it, and what are the appropriate techniques to be adopted in the observations. It also offers schemes for interpreting and reducing the collected data, as well as forms to be filled in and sent to international collection centers.
Extreme NXT : Extending the LEGO MINDSTORMS NXT to the Next Level
Extreme NXT: Extending the LEGO MIDSTORMS NXT to the Next Level is for intermediate-level users of NXT who would like to advance their capabilities by learning some of the basics of electronics. Plenty of examples are provided, and easy-to-follow instructions are included for building over 15 different sensors.
Exploring medicinal orchids
Orchids are fascinating ornamental flowers with a huge market both as cut flowers and potted plants, but they are also used in the traditional medicine system as they can be rich in phytochemicals with exceptional medicinal properties. This book, Exploring Medicinal Orchids, is a comprehensive guide for medicinally important orchids, their diversity, and their use in traditional and folk medicines. It presents information on secondary metabolites of medicinally active orchid species, pharmaceutical and medicinal applications, and describes advanced techniques of biotechnology in the conservation of medicinal orchids.
Experimental Glycoscience : Glycobiology
The aim of this book is to provide experimental protocols covering many aspects of glycobiology, glycotechnology, and chemistry: biochemistry, molecular and cellular biology, genetics, physiology, and medicine. The protocols are all self-contained descriptions of the equipment and reagents needed, followed by details of the experimental procedure.
Experimental analysis of nano and engineering materials and structures ; Proceedings of the 13th international conference on experimental mechanics, Alexandroupolis, Greece, July 1-6, 2007
ICEM13 focused on all aspects of experimental mechanics of solids with emphasis on mechanical characterization and testing at the micro and nano scale levels. The technical program of ICEM13 was the product of hard work and devotion of more than 100 world leading experts. This volume contains two-page abstracts of the 482 papers presented at ICEM13. The accompanying CD contains the full length papers. The abstracts of the fifteen plenary lectures are included in the beginning of the book. The remaining 467 abstracts are arranged in 23 tracks and 28 special symposia/sessions with 225 and 242 abstracts, respectively. The papers of the tracks have been contributed from open call, while the papers of the symposia/sessions have been solicited by the respective organizers.
Existence and Regularity Properties of the Integrated Density of States of Random Schrödinger Operators
The theory of random Schrödinger operators is devoted to the mathematical analysis of quantum mechanical Hamiltonians modeling disordered solids. Apart from its importance in physics, it is a multifaceted subject in its own right, drawing on ideas and methods from various mathematical disciplines like functional analysis, selfadjoint operators, PDE, stochastic processes and multiscale methods. The present text describes in detail a quantity encoding spectral features of random operators: the integrated density of states or spectral distribution function. Various approaches to the construction of the integrated density of states and the proof of its regularity properties are presented.
Examples & explanations for criminal law
Offers hypothetical questions complemented by detailed explanations that allow you to test your knowledge of the topics in your courses and compare your own analysis. Here's why you need an E & E to help you study throughout the semester: Clear explanations of each class topic.
Eutrophication Management and Ecotoxicology
This book aims to bridge the gap between ecotoxicology and limnology. The intended readers of the book are water managers, policy makers with a scientific background as well as researchers/advisors in the area of water management. The book provides an ecotoxicological perspective on lake management and describes eutrophication of shallow, temperate lakes. It surveys the influence of toxic substances (e.g., agricultural pesticides) on the aquatic ecosystem, especially the relation between algae and daphnids. The message of the book is that nutrients such as phosphorus are not the only important factor in explaining and managing eutrophication: toxic disturbance of to-down control is also an important factor to be considered. The results of extensive studies and experiments (some unpublished) on lake eutrophication are presented in this book.
European Guide to Power System Testing : The ERIGrid Holistic Approach for Evaluating Complex Smart Grid Configurations
This book provides an overview of the ERIGrid validation methodology for validating CPES, a holistic power system testing method. It introduces readers to corresponding simulation and laboratory-based tools, including co-simulation, real-time simulation, and hardware-in-the-loop. Selected test cases and validation examples are provided, in order to support the theory discussed.
Ethics in Agriculture : An African Perspective
The role of biotechnology in African agriculture has become a contentious issue. The ethical issues in agriculture in Africa do not focus only on biotechnology. The role of nutrition in the persistence of HIV/AIDS is highly debated and sometimes controversial. Land-related issues also generate heated debates in communities and amongst policy-makers. The single core that runs through all of these and many other related issues is, what are ethically acceptable solutions to these problems? This book attempts, in simple, unambiguous terms, to discuss the most important issues in African agriculture that have an ethical thread.
Esterification of Polysaccharides
Polysaccharide esters (cellulose and starch) are among the first polymeric materials applied commercially. The way of producing these technically relevant derivatives, mainly the carboxylic acid esters of C2 to C4 acids, have not been changed significantly during their history of manufacture. The investigation of new acylation methods and strategies of analysis was revived during the last decade by the search for tailored, biocompatible, material for specific fields of application, e.g., biotechnology, sensor technique and medicine. Unconventional solvents were developed for completely homo-geneous acylation reaction applying state of the art techniques of modern organic chemistry for polysaccharide modification. This book will provide a first comprehensive summary of acylation methods in a very practical manner. Detailed structure analysis is indispensable for the evaluation of structure-property-relationships. Spectroscopic methods in particular FTIR- and NMR spectroscopy including two dimensional methods are of increasing importance.
Essentials of mechanical stress analysis
Essentials of Mechanical Stress Analysis, updated for the second edition, covers stress analysis from an interdisciplinary perspective. Discussing techniques and theories essential to analysing structures, the book covers both analytical and numerical approaches. Also covering beams, plates, columns and elastic instability, the book discusses fatigue, life cycle, energy methods and MathCAD sample code.
Essential Quick Review : Operative Dentistry & Endodontics
Provides a complete outline for writing an essay type, a short answer type, or a viva voce type of questions. Written in a simple language along with well-illustrated diagrams wherever possible. Supported with a supplementary booklet for each subject containing three sections: definitions, classifications, and viva voce.
Essential oils as antibacterial agents
An alarm increase in the rate of emerging of resistant bacteria have been causing a great public concern worldwide. This problem of increasing resistance has necessitated the search for safe and effective factors that may be used to treat persistent bacterial infections or modify the currently available antibiotics. An experimental approach, using agar diffusion method was used to estimate the antibacterial properties of 5 essential oils (cinnamon, clove, peppermint, rosemary and thyme) each one individually, in pure and commercial form, against 3 of the bacterial strains that cause common skin infections which are gram negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and gram positive bacteria (Staphylococcus aureus), obtained from clinical sources. Only two of the commercial oils had an antibacterial effect on both gram negative bacteria (E. coli) and gram positive bacteria (S. aureus) and in lesser extent on gram negative bacteria (P. aeruginosa).synergy.
Essential oils : sources, production and applications
Essential oils are simply the volatile oils of plants. These are concentrated liquids contain many terpenes, alkaloids and alcohols etc. Various compounds of essential oils have bioactive properties such as antimicrobial, anti-cancer, anti-diabetic, anti-viral and anti-fungal etc. This book describes the sources of essential oils, extraction and production method, characterizing tools, bioactivity, and various applications in the field of industries, daily usage, agriculture, health, and food.
Equilibrium statistical physics : Phases of matter and phase transitions
This is a textbook which gradually introduces the student to the statistical mechanical study of the different phases of matter and to the phase transitions between them. Throughout, only simple models of both ordinary and soft matter are used but these are studied in full detail. The subject is developed in a pedagogical manner, starting from the basics, going from the simple ideal systems to the interacting systems, and ending with the more modern topics. The latter include the renormalisation group approach to critical phenomena, the density functional theory of interfaces, the topological defects of nematic liquid crystals and the kinematic aspects of the phase transformation process. This textbook provides the student with a complete overview, intentionally at an introductory level, of the theory of phase transitions. References include suggestions for more detailed treatments and four appendices supply overviews of the mathematical tools employed in the text.
Epidemiology of Drug Abuse
As the drug abuse epidemic evolves, so do the tools needed to understand and treat it. Accordingly, Epidemiology of Drug Abuse takes the long view, cogently outlining what the book calls "the natural history of drug abuse" and redefining its complex phenomena to reflect our present-day knowledge. Twenty-six eminent contributors discuss the state and future of the field, balancing the practical concerns involved in gathering drug abuse data with the ethics of using the information.
Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives
The book covers enzymatic (including chemo-enzymatic) methods, with a focus on the synthesis and incorporation of modified nucleosides. The authors also offer a review of innovative approaches for the non-enzymatic chemical synthesis of nucleic acids and their analogs and derivatives, highlighting especially challenging species. The book offers a concise review of the methods that prepare novel and heavily modified polynucleotides in sufficient amount and purity for most clinical and research applications.
Entry Inhibitors in HIV Therapy
The introductory chapters of this book present an overview of entry inhibitors, review current knowledge of how Env mediates entry, and discuss the challenge of genetic diversity in this region of the viral genome. Subsequent chapters feature current information on individual classes of entry inhibitors that target each step of the virus entry pathway, from attachment to membrane fusion. There is an emphasis on the complex determinants of entry inhibitor susceptibility, resistance mechanisms, the need for clinical phenotyping, and how these issues create new challenges for antiretroviral therapy. Encouraging pre-clinical studies of entry inhibitors as microbicidesare also discussed. The final chapters highlight the current status of entry inhibitors in clinical studies, the major milestone achieved with FDA approval of enfuvirtide, and review drug development, past and present.
