الصفحة 10
الصفحة 10
Epigenetics in oncology
Covers the most recent advances in RNA/histone/DNA epigenetics in Oncology. RNA/histone/DNA epigenetics have been shown to play pivotal roles in cancer initiation, progression, maintenance and drug response/resistance, tumor microenvironment, cancer stem cell self-renewal, cancer metabolism, and tumor immune evasion. In particular, research in RNA cancer epigenetics has made impressive progress in the last few years. Individual chapters in Part I (focusing on RNA epigenetics) are devoted to RNA modifications in Cancer Metabolism and Microenvironment, Cancer Stem Cell Biology, Immune Surveillance, Solid Tumors and Tumor Immunity, and Hematopoietic Malignancies, as well as to RNA editing in Cancer. Chapters in Part II and III of the book focus on histone epigenetics and DNA epigenetics, respectively.
Environmental Health in Central and Eastern Europe
Complex chemical mixtures impact our health every day. In the United States, and also in Central and Eastern Europe, there are a number of locations where complex chemical mixtures have been released to environmental media. Although exposure to mixtures is common, minimal information exists to quantify these exposures, or to determine their impact on human or ecological receptors. These proceedings present some of the most current research conducted to quantify complex mixtures in the environment and investigate their potential impact on human health. Many of the manuscripts reported in these proceedings represent the most up-to-date measurements of population exposures in Central and Eastern Europe. These studies are of value to health and environmental professionals around the world as they develop strategies for assessing exposures, remediating contaminated environments, and improving public health.
Endourooncology : New Horizons in Endourology
Recent research and clinical work have demonstrated that the rapid urologic innovation in minimally invasive treatment is creating exciting new horizons in endourology. This sixth volume in the series Recent Advances in Endourology brings that knowledge to a wider audience, focusing on the new concept of endourooncology, which is the merging of endourology and oncology. In the surgical treatment of urologic malignancies, bipolarization - that is, radical extended resection or organ-sparing surgery - is making remarkable advances. Further developments in sophisticated reconstructive surgery using robotic systems and image-guided ablation technology will allow surgeons to formulate minimally invasive, tailor-made procedures for each patient with urologic cancer. In this book, the current status and future prospects of these new technologies are reviewed, illuminating their roles in the future of endourooncology.
Endourological Management of Urogenital Carcinoma
This seventh volume in the series focuses on the treatment of urogenital malignancies by endourological procedures, including laparoscopic surgery with robotic assistance. The standard procedures and their relatively long-term outcomes as well as new techniques have been clearly described with detailed references. This book provides a better understanding of the present status of endourological management for urogenital carcinoma and sets the stage for future improvements in both oncological and functional outcomes.
Endoscopic Oncology
Endoscopic Oncology: Gastrointestinal Endoscopy and Cancer Management examines the interface between endoscopy and oncology, and its utilization in the prevention, diagnosis, and management of cancer. Organized anatomically, chapters covering relevant cancers and premalignant conditions of the esophagus, stomach, colorectum, and pancreaticobiliary are explored in depth.
Endoscopic Extraperitoneal Radical Prostatectomy : Laparoscopic and Robot-Assisted Surgery
This book is an atlas, not a conventional textbook. Its main goal is to guide the urologist step by step through EERPE, aiming to make this highly standardized technique reproducible. Every stage of the procedure is presented with numerous endoscopic images and diagrams so that the reader can fully comprehend the different surgical steps. Complications and their management are described in detail. Special chapters are devoted to the anatomy of the prostate, anesthesiological considerations, and postoperative management and training.
Encyclopedia of Genetics, Genomics, Proteomics and Informatics
It includes about 56% more words than the 1,392-page 2nd edition of 2003. The number of illustrations increased to almost 2,000 and their quality has improved by design and four colors. Cross-references among entries are expanded. The statements are supported by references; more than 14,000 journal papers and more than 3,000 books are listed. The book includes ~1,800 current databases and web servers. Retractions and corrigenda are pointed out.It covers the basics and the latest in genomics, proteomics, genetic engineering, small RNAs, transcription factories, chromosome territories, stem cells, genetic networks, epigenetics, prions, hereditary diseases, patents, etc. Similar integrated information is not available in textbooks or on the Internet. The journal reviews called it the best, high-quality resource for researchers, instructors and students of basic and applied biology, as well as for physicians and lawyers or even for interested laymen because of the clarity of presentation.
EGFR Signaling Networks in Cancer Therapy
EGFR Signaling Networks in Cancer Therapy, is separated into two sections. The first of which probes the molecular pathways and the intersection of signaling networks which are frequently deregulated in human cancers, the second section illustrates the many ways in which EGF receptor contribute to abnormal survival and migration signaling in cancer cells and to epithelial to mesenchymal transition and metastasis.
Effect of Cranberry in the Treatment of E. Coli
Escherichia coli (E. coli) bacteria normally live in the intestines of healthy people and animals. It may cause severe stomach cramps, bloody diarrhoea, vomiting and UTI. You may be exposed to E. coli from contaminated water or food especially raw vegetables and undercooked ground beef. Healthy adults usually recover from infection with E. coli within a week. Young children and older adults have a greater risk of developing a life-threatening form of kidney failure. Cranberries are a popular superfood. People can consume them in the form of a sauce or a juice. They can also add them to stuffing, casseroles, or dessert. In fact, research has linked the nutrients in cranberries to a lower risk of urinary tract infection (UTI), the prevention of certain types of cancer, improved immune function, and decreased blood pressure
Edible Plants in Health and Diseases ; Vol.1 : Cultural, Practical and Economic Value
Provides significant information on some of the promising edible medicinal plants and how these possess both nutritive as well as medicinal value. The significance of these edible plants in traditional medicine, their distribution in different regions and the importance of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume focuses on the economic and culturally important medicinal uses of edible plants and a detailed survey of the literature on scientific researches of pharmacognostical characteristics, traditional uses, scientific validation, and phytochemical composition, and pharmacological activities. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits, as well as discussing how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists as well as all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
Edible Plants in Health and Diseases ; Vol. II : Phytochemical and Pharmacological Properties
Provides essential information on some of the promising edible medicinal plants and how these possess both nutritional as well as therapeutic value. The significance of the edible plants in traditional medicine and the importance of the distribution of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume deals with the individual plants' phytochemical and pharmacological properties, emphasizing human health. The title would demonstrate the value of natural edible plants and introduce readers to state-of-the-art developments and trends in omics-driven research.
Early Cancer of the Gastrointestinal Tract : Endoscopy, Pathology, and Treatment
Differences in the diagnostic criteria for early cancer of the gastrointestinal tract between Japan and Western countries have been an interesting issue for some time, physicians in Japan being much more inclined to give a diagnosis of cancer than their European and North American counterparts. This book addresses those differences by contrasting the views of Eastern and Western endoscopists and pathologists on 24 cases presented in Part I.
Dynamic Radiology of the Abdomen : Normal and Pathologic Anatomy
Meyers' Dynamic Radiology of the Abdomen, extensively revised and updated, is the classic text covering radiology of the abdomen as it relates to the progression of disease within an organ and from one organ to another. The book provides a systematic application of anatomic and dynamic principles to the practical understanding and diagnosis of intraabdominal disease. The full range of imaging modalities is addressed, from plain films and conventional contrast studies to CT, US, MRI and endoscopic ultrasonography. Highly selected, ample images including CT and MRI support the thoroughly descriptive text. Expanded references, citing both the classic and recent contributions, and a detailed cross-referenced index are presented. For radiologists, general surgeons, gastroenterologists, and others seeking insight into the clinical practice of radiology, this text continues to be the gold standard in the field.
Drugs Affecting Growth of Tumours
During recent years the field of effective anticancer agents has substantially increased. The use of chemotherapy has been accepted as a standard therapy for an expanding number of tumour types and stages, while many new agents are being investigated when standard therapy is lacking or failing. Apart from new targets for anticancer agents, attention is also focused on improving efficacy and tolerability of existing compounds. This topical volume provides an up-to-date overview of clinically relevant data on anticancer agents, and is not only intended for those working as a medical doctor with cancer patients, but also for medical researchers and students. The different classes of anticancer drugs are described by international authorities on the various topics.
Drug Delivery Systems
Expands on the previous editions with a discussion of new and updated methods used to study drug delivery. Chapters cover topics such as drug delivery in cancer and intrathecal delivery of analgesics in humans. The increasing role of nanobiotechnology is reflected in eight of the sixteen chapters that include synthesis of gold nanoparticles; targeted siRNA delivery; and lipid nanocarriers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Drug delivery : An integrated clinical and engineering approach
Offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for such topics as oral, gastroretentive, intravitreal, and intrathecal drug delivery, as well as insulin delivery, gene delivery, and biomaterials-based delivery systems. It also describes drug delivery in cancer, cardiac, infectious diseases, airway diseases, and obstetrics and gynecology applications.
DNA vaccines : Methods and protocols
Details practical procedures on the latest DNA vaccine technology. Chapters guide readers through methods and protocols on DNA vaccine design, the adjuvant influence, production and purification methodologies, delivery systems, and approaches of the influence of DNA vaccines in the immunological response performance and in the cancer immunotherapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
DNA Repair and Human Disease
DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.
DNA Methylation, Epigenetics and Metastasis
Provides an outline of the epigenetic mechanisms involved in cancer progression and the generation of metastasis. This book describes the tumor suppressor genes undergoing transcriptional silencing by CpG island promoter hypermethylation in the different tumor types of the human anatomy and their association with tumoral behaviour
DNA Methylation and Cancer Therapy
DNA methylation pat terns emerged as the only component of the chemical structure of DNA that exhibited tissue and cell specificity. This data seemingly provided an attrac tively simple explanation for the longstanding dilemma of how could one identical genome manifest itself in so many different forms in multicellular organisms? The DNA methylation pattern has thus become the only known factor to confer upon DNA a unique cellular identity.
