الصفحة 10
الصفحة 10
Drugs, the brain, and behavior : The pharmacology of therapeutics and drug use disorders
Provides a comprehensive overview of the brain and explores the clinical and pharmacological issues surrounding drug abuse and dependence. Dr Brick provides definitions, historic discoveries about the nervous system, and original, eye-catching illustrations to discuss the brain/behavior relationship, basic neuroanatomy, neurophysiology, and the mechanistic actions of mood-altering drugs. Topics include: how psychoactive drugs affect cognition, behavior, and emotion; the brain/behavior relationship; the specific effects of major addictive and psychoactive drug groups; new definitions and thinking about abuse and dependence; and the medical uses of drugs, such as cannabinoids. A new chapter on biobehavioral markers explores how markers can guide the clinician in the diagnosis of some disorders. This book offers a quick reference guide which uses a balance of instruction, illustrations, tables, and formulas, that will give you a broad, lasting introduction to this intriguing subject.
Drugs Compromising Male Sexual Health
This concise drug guide lists approximately 500 substances, such as pharmaceutical drugs, lifestyle drugs, and environmental toxicants, that show documented untoward effects on the male sexual organs and their functions.
Drugs and Poisons in Humans : A Handbook of Practical Analysis
At the beginning of the book, general topics are addressed, including instructions on h- dling biological materials, measurement of drugs in alternative specimens, and guidance on resolving analytical problems that may occur. T ere are discussions of extraction modalities and detection methodologies and how to select these appropriately based on the physioche- cal characteristics of the drug. Analysis of specif c classes of drugs and relevant metabolites are covered in subsequent chapters.
Drug Testing in Alternate Biological Specimens
Drug Testing in Alternate Biological Specimens provides researchers and forensic toxicologists with a convenient general text summarizing the state of knowledge today.
Drug discovery targeting drug-resistant bacteria
Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included.
DNA Methylation : Development, Genetic Disease and Cancer
It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many fields of biology and medicine such as developmental biology, genetic imprinting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems.
DNA Methylation : Basic Mechanisms
The structural and functional importance of the correct patterns of DNA methylation in all parts of a mammalian genome is not well understood. The stability, inheritability, and developmental flexibility of these patterns point to a major role that these patterns appear to play in determining structure and function of the genome.
Distributed Ledgers : Design and Regulation of Financial Infrastructure and Payment Systems
In this book, Robert Townsend steps back from the hype and controversy surrounding DLT (and the related, but not synonymous, innovations of blockchain and Bitcoin) to offer an economic analysis of what distributed ledgers can do and a blueprint for the optimal design and regulation of financial systems. He analyzes four crucial components of distributed ledgers—ledgers as accounts, e-messages and e-value transfers, cryptography, and contracts—assessing each in terms of both economics and computer science, and forges some middle ground. Relatedly, Townsend highlights hybrid systems in which some of these components allow useful innovation while legacy or alternative pieces deal with the problem of scale.
Digital video and audio broadcasting technology : A practical engineering guide
"Digital Video and Audio Broadcasting Technology – A Practical Engineering Guide" deals with all the most important digital television, sound radio and multimedia standards such as MPEG, DVB, DVD, DAB, ATSC, T-DMB, DMB-T, DRM and ISDB-T. The book provides an in-depth look at these subjects in terms of practical experience.
Digital Kenya : An Entrepreneurial Revolution in the Making
Presenting rigorous and original research, this volume offers key insights into the historical, cultural, social, economic and political forces at play in the creation of world-class ICT innovations in Kenya. Following the arrival of fiber-optic cables in 2009, Digital Kenya examines why the initial entrepreneurial spirit and digital revolution has begun to falter despite support from motivated entrepreneurs, international investors, policy experts and others. Written by engaged scholars and professionals in the field, the book offers 15 eye-opening chapters and 14 one-on-one conversations with entrepreneurs and investors to ask why establishing ICT start-ups on a continental and global scale remains a challenge on the “Silicon Savannah
Differential Information Economies
One of the main problems in current economic theory is to write contracts which are Pareto optimal, incentive compatible, and also implementable as a perfect Bayesian equilibrium of a dynamic, noncooperative game. The question arises whether it is possible to provide Walrasian type or cooperative equilibrium concepts which have these properties. This volume contains original contributions on noncooperative and cooperative equilibrium notions in economies with differential information and provides answers to the above questions. Moreover, issues of stability, learning and continuity of alternative equilibria are also examined.
Designing Democracy : Ideas for Better Rules
While liberal democracies are the best systems of self-governance for societies, they rarely invoke great enthusiasm. On the one hand, democracies have been known to fail in achieving efficient or fair allocations. On the other hand, many citizens take the democratic system for granted as they have yet to experience an alternative. In this book the vision we propose is that the potential of democ racies has not yet been exhausted, and that optimal democracies are both the Utopia for societies and the aim that scientists should be committed to. We present a number of ideas for drawing up new rules to im prove the functioning of democracies. The book falls into two parts. The first part examines ways of combining incentive contracts with democratic elections. We suggest that a judicious combina tion of these two elements as a dual mechanism can alleviate a wide range of political failures, while at the same time adhering to the founding principles of democracies. The second part presents new rules for decision-making and agenda setting. Together with modern communication devices, these rules can sometimes transcend the limitations of liberal VI Preface democracies in achieving desirable outcomes. Examples of such rules include the flexible majority rule where the size of the ma jority required depends on the proposal, or the rule that only those belonging to the winning majority can be taxed.
Design applications of raft foundations
Examines alternative design procedures for plain and piled raft foundations. Chapters are written by leading consultants and contractors from around the world who draw on their extensive experience in the UK and overseas. It explores the broad assumptions that are made in the analysis of soil - structure interaction, together with the associated calculation methods. In particular, the book contains extensive references to recent work on the subject, and gives many examples of project applications covering a wide range of structural forms and ground conditions.
Dependence in Probability and Statistics
This book gives a detailed account of some recent developments in the field of probability and statistics for dependent data. The book covers a wide range of topics from Markov chain theory and weak dependence with an emphasis on some recent developments on dynamical systems, to strong dependence in times series and random fields. A special section is devoted to statistical estimation problems and specific applications. The book is written as a succession of papers by some specialists of the field, alternating general surveys, mostly at a level accessible to graduate students in probability and statistics, and more general research papers mainly suitable to researchers in the field. The first part of the book considers some recent developments on weak dependent time series, including some new results for Markov chains as well as some developments on new notions of weak dependence. This part also intends to fill a gap between the probability and statistical literature and the dynamical system literature. The second part presents some new results on strong dependence with a special emphasis on non-linear processes and random fields currently encountered in applications. Finally, in the last part, some general estimation problems are investigated, ranging from rate of convergence of maximum likelihood estimators to efficient estimation in parametric or non-parametric time series models, with an emphasis on applications with non-stationary data.
Dental pathology : A practical introduction ; 2nd ed.
Invaluable companion that will assist dentists and oral surgeons in recognizing and diagnosing gross dental abnormalities. New, updated edition with more figures and information on diagnostically difficult cases. Will help pathologists to increase their diagnostic skills. Includes diagnosis of histological alterations due to dental treatment
Dental Hard Tissues and Bonding : Interfacial Phenomena and Related Properties
This book comprehensively reviews bonding to enamel, dentin and cementum and analyses relevant adhesion mechanisms. Emphasis is placed on the characterization of material interfaces with dental tissues in situ. The volume also stresses the importance of appropriate experimental protocol design in facilitating clinically-relevant research methods, clarifies the mechanisms of adhesion of polymeric materials to hard dental tissues and furnishes a handy reference for routine clinical procedures in restorative and prosthetic dentistry as well as orthodontics. The book introduces important aspects of the chemistry of dental materials and their adaptation to dental hard tissues. It also analyses interfacial phenomena occurring during application of materials, including mechanical properties, and structural-compositional alterations. The text presents the current instrumental approaches in studying related issues and a summary of the current status of theories concerning bonding to dental tissues.
Dental Care for Children with Special Needs : A Clinical Guide
This concise manual offers best practice guidance on dental treatment of pediatric patients with special health care needs (CSHCN). Readers will find up-to-date information on case-based treatment planning, alternative caries management strategies, the use of behavioral and pharmacological interventions to facilitate delivery of quality treatment, and a team approach to care.
Dendrimer Catalysis
catalytically active dendrimers have emerged as a class of molecular catalysts that has substantially enriched the field of homogeneous (and in part heterogeneous) catalysis. A general survey of transition metal dendrimer catalysts and the way they have developed is followed by in-depth discussions of dendritic transition metal catalysis based on non-covalent catalyst-support interaction and an overview of the rapidly growing field of stereoselective dendrimer catalysis. The development of dendrimer-encapsulated bimetallic nanoparticles has provided the interface with heterogeneous colloid catalysis. As cheaper and readily accessible alternatives to regular dendrimers, hyperbranched polymers are increasingly being used as catalyst platforms. These topics are complemented by a review of metallodendritic exoreptors for the redox recognition of oxo-anions and halides.
Defects in High-k Gate Dielectric Stacks : Nano-Electronic Semiconductor Devices
One of the key obstacles to high-k integration into Si nano-technology are the electronic defects in high-k materials. It has been established that defects do exist in high-k dielectrics and they play an important role in device operation. However, very little is known about the nature of the defects or about possible techniques to eliminate, or at least minimize them. Given the absence of a feasible alternative in the near future, well-focused scientific research and aggressive development programs on high-k gate dielectrics and related devices must continue for semiconductor electronics to remain a competitive income producing force in the global market.
Deep eutectic polvents : Synthesis, properties, and applications
Deep Eutectic Solvents contains a comprehensive review of the use of deep eutectic solvents (DESs) as an environmentally benign alternative reaction media for chemical transformations and processes. The contributors cover a range of topics including synthesis, structure, properties, toxicity and biodegradability of DESs. The book also explores myriad applications in various disciplines, such as organic synthesis and (bio)catalysis, electrochemistry, extraction, analytical chemistry, polymerizations, (nano)materials preparation, biomass processing, and gas adsorption.
