الصفحة 10
الصفحة 10
Attention deficit hyperactivity disorder (ADHD) : Awareness in Syrian communities
Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder affecting both children and adults, characterized by inattention, hyperactivity, and impulsivity. This research explores ADHD awareness, prevalence, diagnosis, and treatment preferences within Syrian communities. A survey was conducted to collect data from individuals regarding their awareness of ADHD, its diagnosis, and treatment preferences. Additionally, interviews with specialists provided insights from medical professionals on the diagnosis and management of ADHD.
Asset prices, booms and recessions : Financial economics from a dynamic perspective
Studies the interaction of the financial market, economic activity and the macroeconomy from a dynamic perspective. The financial market to be studied here encompasses the money and bond market, credit market, stock market and foreign exchange market. Economic activity is described by the activity of firms, banks, households, governments and countries. The book shows how economic activity affects asset prices and the financial market and how asset prices and financial market volatility feed back to economic activity. The focus in this book is on theories, dynamic models and empirical evidence.
Aspects of physical biology : Biological water, protein solutions, transport and replication
The present volume focuses on three main subtopics (biological water, protein solutions as well as transport and replication), presenting for each of the them the on-going debates on recent results. The role of water in biological processes, the mechanisms of protein folding, the phases and cooperative effects in biological solutions, the thermodynamic description of replication, transport and neural activity, all are subjects that are revised in this volume, based on new experiments and new theoretical interpretations.
Aspects of mathematical modelling : Applications in science, medicine, economics and management
The construction of mathematical models is an essential scientific activity. Mathematics has long been associated with developments in the exact sciences and engineering, but more recently mathematical modelling has been used to investigate complex systems that arise in many other fields. The contributors to this book demonstrate the application of mathematics to modern research topics in ecology and environmental science, health and medicine, phylogenetics and neural networks, theoretical chemistry, economics and management. The reader will find some review papers outlining current research directions in hot topics such as pattern formation and applications to medicine, and more targeted research papers on current developments in the various disciplines included.
Artificial intelligence in drug design
Looks at applications of artificial intelligence (AI), machine learning (ML), and deep learning (DL) in drug design. The chapters in this book describe how AI/ML/DL approaches can be applied to accelerate and revolutionize traditional drug design approaches such as: structure- and ligand-based, augmented and multi-objective de novo drug design, SAR and big data analysis, prediction of binding/activity, ADMET, pharmacokinetics and drug-target residence time, precision medicine and selection of favorable chemical synthetic routes. How broadly are these approaches applied and where do they maximally impact productivity today and potentially in the near future.
Applying the Kaizen in Africa : A New Avenue for Industrial Development
At present, how to develop industries is a burning issue in Africa, where population growth remains high and economic development has thus far failed to provide sufficient jobs for many, especially young people and women. The creation of productive jobs through industrial development ought to be a central issue in steering economic activity across the continent.The authors of this book, consisting of two development economists and five practitioners, argue that the adoption of Kaizen management practices, which originated in Japan and have become widely used by manufacturers in advanced and emerging economies, is decisively the most effective first step for industrial development in Africa.This open access book discusses what Kaizen management is, why it is applicable to Africa, and why it can provide Africa with a springboard for sustainable economic growth and employment generation.
Application of muscle/nerve stimulation in health and disease
The first evidence that electrical changes can cause muscles to contract was p- vided by Galvani (1791). Thus, elect- cal activity graduated from a simple mechanism that is used to elicit muscle c- traction, to a system that could induce permanent changes in muscles and modify most of its characteristic properties.
Antioxidants effects in health : The bright and the dark side ; 1st ed.
Examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants’ historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.
Anti-Money Laundering : A Practical Guide to Reducing Organizational Risk
Addresses the needs of the non-specialist compliance professional from a range of industries, backgrounds and experience Outlines the different elements of anti-money laundering (AML) practice to support compliance professionals at any stage of their career to put effective controls in place in their own organisations Presents readers with the global oversight needed to align activity to a cohesive plan, sharing case studies and examples of good and bad practice from around the world
Antimalarial natural products
Begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type.
Antidiabetic plants for drug discovery pharmacology, secondary metabolite profiling, and ingredients with insulin mimetic activity
Takes an in-depth look at the potential pharmacological applications of 11 important antidiabetic plants, examining their antihyperglycemic, hypoglycemic, and anti-lipidemic properties along with current genome editing research perspectives. Plant natural products, or phytoconstituents, are promising candidates for antidiabetic pharmacological actions. The phytoconstituents, such as fl avonoids, terpenoids, saponins, carotenoids, alkaloids and glycosides, play vital roles in the current and future potent antidiabetic drug development programs. Each chapter reviews a particular plant with antidiabetic properties, explaining the therapeutic aspects, its active antidiabetic compounds, and relevant genome editing technology.
Antidepressants Beyond Depression, and Into Bacteria
Antidepressants are one of the most predominant drug groups in the pharmaceutical world, primary care units and the general public. Their original use was majorly for the treatment of depression along with other mental disorders. Today, antidepressant consume over 20% of the medical prescriptions and healthcare plans due to their recently discovered applications outside the psychiatry field. Due to the alarming rise of antibiotic resistance and the slow pace of new drug discovery, the world has been searching frantically for new or alternative drugs with antibacterial activity. Repurposing already FDA- approved drugs for uses that are off-label has become an important preposition in the pharmacy world due to its availability, low risk and low cost.
Anticancer activity in heterocyclic organic structures : A pathway to novel drug development : Part 1
New Directions in Organic & Biological Chemistry, explores the development of cancer therapeutics, focusing on molecular chemistry and advanced drug design approaches. Written by experts in theoretical chemistry and molecular chemistry, they bridge the gap between theoretical chemistry, molecular biology, and drug development. In Part I, they focus on the fundamental properties of heterocyclic compounds and innovative methodologies being employed to enhance therapeutic potential. By exploring various classes of heterocyclic compounds and diverse anticancer mechanisms.
Antibody-drug conjugates and cellular metabolic dynamics
Summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets of ADCs and their specific functions. The second part mainly introduces the endocytosis and intracellular metabolism of ADCs, including the relationship between endocytosis and ADC activity, the endocytosis and intracellular transport of ADCs, the distribution and metabolism of ADC in vivo. Then it discusses the new formats and research technology of ADCs, including the application of miniaturized antibodies in ADC synthesis, novel carriers for ADC design, the technology and application of site-specific conjugation, and approaches for analyzing the drug: antibody ratio (DAR), the study of pharmacokinetics of ADCs.
Ambient Intelligence ; European Conference, AmI 2008, Nuremberg, Germany, November 19-22, 2008. Proceedings
This book constitutes the refereed proceedings of the Second European Conference on Ambient Intelligence, AmI 2008, held in Nuremberg, Germany, in November 2008.
Ambient Intelligence ; European Conference, AmI 2007, Darmstadt, Germany, November 7-10, 2007, Proceedings
This book presented sections on mobility and sensing, applications of AmI, activity and location sensing, AmI and artificial intelligence, AmI middleware and infrastructure, and interaction with the environment. The book is rounded off by a section on case studies and lessons learned, presenting a high level selection of current research reports and papers that reflect the most important activities of current ambient intelligence research.
Alternative medicine and it's uses in the treatment of kidney disease
The aim of this article was to review some of the new and commonly and alternative medicine in the treatment of kidney used medicinal plants , pharmacological activity, and research study of disease, kidney stones medicinal plants. Renal stones are a common problem worldwide with rden substantial morbidities and economic costs. The high economic bu associated with kidney stones is linked mainly with healthcare costs. In vitro and in vivo studies on alternative treatment of kidney stones have been searched by using words such as phytotherapy of kidney stones,. lithotriptic activity of plantss, and medicinal plants used in kidney stone Medicinal plants may be useful in treatment of kidney stones.
Allergic rhinitis
Allergic rhinitis is a very common disorder that affects people of all ages, peaking in the teenage years. It is frequently ignored, underdiagnosed, misdiagnosed, and mistreated, which not only is detrimental to health but also has societal costs. Although allergic rhinitis is not a serious illness, it is clinically relevant because it underlies many complications, is a major risk factor for poor asthma control, and affects quality of life and productivity at work or school. Management of allergic rhinitis is best when directed by guidelines. A diagnostic trial of a pharmacotherapeutic agent could be started in people with clinically identified allergic rhinitis; however, to confirm the diagnosis, specific IgE reactivity needs to be recorded.
Agricultural Implications of the Fukushima Nuclear Accident : The First Three Years
Consists of various topics, including radioactivity inspection of food products; decontamination trials for rice and livestock production; the state of contamination in wild animals and birds, trees, mushrooms, and timber; the dynamics of radioactivity distribution in mountain and paddy fields; damage incurred by the forestry and fishery industries; and the change in consumers’ minds. The last chapter introduces a real-time radioisotope imaging system, the forefront technique to visualize actual movement of cesium in soil and in plants. This is the only book to provide systematic data about the actual change of radioactivity, and thus is of great value for all researchers who wish to understand the effect of radioactive fallout on agriculture.
Agricultural Implications of the Fukushima Nuclear Accident (III)
Reports on studies undertaken at contaminated sites such as farmland, forests, and marine and freshwater environments, with a particular focus on livestock, wild plants and mushrooms, crops, and marine products in those environments. It also provides additional data collected in the subsequent years to show how the radioactivity levels in agricultural products and their growing environments have changed with time and the route by which radioactive materials entered agricultural products as well as their movement between different components (e.g., soil, water, and trees) within an environmental system (e.g., forests). The book covers various topics, including radioactivity testing of food products; decontamination trials for rice and livestock production; the state of contamination in, trees, mushrooms, and timber; the dynamics of radioactivity distribution in paddy fields and upland forests; damage incurred by the forestry and fishery industries; and the change in consumers’ attitudes. Chapter 19 introduces a real-time radioisotope imaging system, a pioneering technique to visualize the movement of cesium in soil and in plants.
