الصفحة 1
الصفحة 1
Zinc Finger Proteins: From Atomic Contact to Cellular Function
The scientists discovered a novel domain associated with zinc, and named this domain "zinc finger. " The number of proteins with similar zinc fingers grew quickly and these proteins are now called C2H2, Cys2His2 or classical zinc finger proteins. To date, about 24,000 C2H2 zinc finger proteins have been recognized. Approximately 700 human genes, or more than 2% of the genome, have been estimated to encode C2H2 finger proteins. From the beginning these proteins were thought to be numerous, but no one could have predicted such a huge number. Perhaps thousands of scientists are now working on C2H2 zinc finger proteins fi-om variou s viewpoints. This field is a good example of how a new science begins with the insight of a few scientists and how it develops by efforts of numerous independent scientists, in contrast to a policy-driven scientific project, such as the Human Genome Project, with goals clearly set at its inception and with work performed by a huge collaboration throughout the world. As more zinc finger proteins were discovered, several subfamilies, such as C2C2, CCHC, CCCH, LIM, RING, TAZ, and FYVE emerged, increasing our understanding of zinc fingers. The knowledge was overwhelming. Moreover, scientists began defining the term "zinc finger" differently and using various names for identical zinc fingers.
Yeasts in Food and Beverages
This book provides a comprehensive account of the ecology, physiology, biochemistry, molecular biology, and genomics of the diverse range of yeast species associated with the production of foods and beverages.
Workbook small business management : Theory and practice, 4th
Familiarises students with the theory and practice of small business management and challenges assumptions that may be held about the way small business management can or should adopt the management practices of larger firms. For students interested in establishing and managing their own small firm, This book helps them to focus their thinking on the realities of life as a small business owner-manager – both its challenges and its rewards. For postgraduate students that are keen to ‘make a difference’, This text enables them to understand how they might consult to small firms and assist owner-managers to establish and grow their ventures.
Words and Intelligence II : Essays in Honor of Yorick Wilks
This book celebrates the work of Yorick Wilks from the perspective of his peers. It consists of original chapters each of which analyses an aspect of his work and links it to current thinking in that area. His work is pertinent to recent developments in language processing such as the Semantic Web.
Words and Intelligence I : Selected Papers by Yorick Wilks
The papers include early work descriptions of groundbreaking work on Machine Translation and Preference Semantics as well as more recent works on belief modeling and computational semantics. The selected papers reflect Yorick’s contribution to both practical and theoretical aspects of automatic language processing.
Women in Space - Following Valentina
Dave Shayler tells the story of the first woman balloonist in 1784 to their breakthrough as astronauts and cosmonauts in a range of professional roles. He covers the contribution women have made to space exploration and draws on interviews with Shuttle and Mir crew members who were women. These interviews detail the achievements of the first female Shuttle commander and the first female resident crew member of the International Space Station. These and many other events are presented in a detailed and highly readable account that recalls the difficult path to space exploration by women.
Windows Vista : Beyond the Manual
Windows Vista: Beyond the Manual is a comprehensive guide to installing, configuring, exploiting, and using the richest Microsoft client operating system on the market. It guides you through the complexities of configuring and running a successful Windows Vista client computer. It also takes an in-depth look at the wealth of features and functions comprising the various flavors of the software.
Windows Home Server Users Guide
If you're searching for a practical and comprehensive guide to installing, configuring, and troubleshooting Microsofts Windows Home Server, look no further. Inside Windows Home Server User's Guide, you'll learn how to install, configure, and use Windows Home Server and understand how to connect to and manage different clients such as Windows XP, Windows Vista, Windows Media Center, and more. It's straightforward and easy-to-understand style will help you maximize all the benefits that Windows Home Server can bring.
When Things Don't Fall Apart : Global Financial Governance and Developmental Finance in an Age of Productive Incoherence
Intro -- Contents -- Foreword -- Preface -- List of Abbreviations -- I. Crises, Change, and Productive Incoherence -- 1. Introduction: Contesting Continuity -- Purpose of Book -- The Continuity Thesis -- An Alternative Change Framework: Productive Incoherence -- Related Literature, Caveats, and Risks -- Clarification of Terms -- The Book in Brief -- 2. Productive Incoherence: A Hirschmanian Perspective -- A
Web Information Systems Engineering – WISE 2007 ; 8th International Conference on Web Information Systems Engineering, Nancy, France, December 3-7, 2007, Proceedings
Cover a wide and important va-riety of issues in Web information systems engineering such as querying; trust;caching and distribution; interfaces; events and information filtering; data extrac-tion; transformation and matching; ontologies; rewriting, routing and personal-ization; agents and mining; quality of services and management and modelling.
Vocal Fold Paralysis
New therapeutic options and approaches have been developed based on an expanded knowledge of the underlying pathophysiology of vocal fold paralysis. The core of Vocal Fold Paralysis offers step-by-step descriptions and of the following therapies: vocal fold injection, medialization laryngoplasty, and arytenoid repositioning surgery. It also includes special topics such as reinnervation, vocal fold pacing, bilateral medialization, and pediatric and bilateral vocal fold paralysis. Vocal Fold Paralysis is a clinically useful reference for evaluation and treatment, as well as a summary of current knowledge and investigational approaches. This excellent guide fills a void within the field of otolaryngology and should not be missed by any otorhinolaryngologist, neurologist, phoniatrician or speech pathologist.
Vascular Surgery : Cases, Questions and Commentaries
This updated and revised second edition of Vascular Surgery: Cases, Questions and Commentaries provides a thorough overview of the management principles of clinical cases in vascular surgery. It also summarizes all the relevant topics the vascular trainee is expected to be familiar with. This book serves as a teaching resource for vascular trainees or practitioners who are reviewing for the oral board exam or practitioners who wish to refresh their expertise with an interactive source of information. It also provides established practitioners the wherewithal to review the current standards of practice in vascular surgery.
Uncertainty Theory
Uncertainty theory is a branch of mathematics based on normality, monotonicity, self-duality, and countable subadditivity axioms. The goal of uncertainty theory is to study the behavior of uncertain phenomena such as fuzziness and randomness. The main topics include probability theory, credibility theory, and chance theory. For this new edition the entire text has been totally rewritten. More importantly, the chapters on chance theory and uncertainty theory are completely new. This book provides a self-contained, comprehensive and up-to-date presentation of uncertainty theory. The purpose is to equip the readers with an axiomatic approach to deal with uncertainty. Mathematicians, researchers, engineers, designers, and students in the field of mathematics, information science, operations research, industrial engineering, computer science, artificial intelligence, and management science will find this work a stimulating and useful reference.
Types for Proofs and Programs ; International Workshop, TYPES 2004, Jouy-en-Josas, France, December 15-18, 2004, Revised Selected Papers
Cover all current issues of formal reasoning and computer programming based on type theory are addressed; in particular languages and computerised tools for reasoning, and applications in several domains such as analysis of programming languages, certified software, formalisation of mathematics and mathematics education.
Typed Lambda Calculi and Applications ; 8th International Conference, TLCA 2007, Paris, France, June 26-28, 2007, Proceedings
Constitutes the refereed proceedings of the 8th International Conference on Typed Lambda Calculi and Applications, TLCA 2007, held in Paris, France in June 2007 in conjunction with RTA 2007, the 18th International Conference on Rewriting Techniques and Applications as part of RDP 2007, the 4th International Conference on Rewriting, Deduction, and Programming. The 25 revised full papers presented together with 2 invited talks were carefully reviewed and selected from 52 submissions. The papers present original research results that are broadly relevant to the theory and applications of typed calculi and address a wide variety of topics such as proof-theory, semantics, implementation, types, and programming.
Type Synthesis of Parallel Mechanisms
Focuses on the systematic type synthesis of parallel mechanisms (PMs), which is a key issue in the creative design of a wide variety of innovative devices based on PMs such as parallel manipulators, parallel kinematic machines (machine tools), motion simulators, haptic devices, micro-manipulators, and nano-manipulators. Type synthesis of PMs refers to finding all the types of PMs realizing a specified motion requirement. This book covers the classification of PMs and an efficient method for the type synthesis of PMs and also provides a large number of PMs ready to be used in practical applications. The synthesis approach is based on the concept of virtual chain and the elementary notions of screw theory.
Transplantation of Composite Tissue Allografts
This book reviews, updates, and synthesizes the recent accomplishments and ongoing research in the field of composite tissue allotransplantation (CTA). The volume focuses on the immunology, biotechnology, and bioengineering of CTA, as these areas have demonstrated the most growth within the field in the last five years. The text presents the entire scope of CTA in a comprehensive format. This effort details the state-of-the-art advances in CTA and includes the numerous accomplishments of premier scientists and physicians from around the world engaged in the field. Significant advancements in the evolution of CTA are detailed from the historic legend of "Cosmas and Damian" through the most recent controversial topics of hand and face transplantation.
Toward Agroforestry Design : An Ecological Approach
Jose and Gordon’s Toward Agroforestry Design is an important reference for anyone interested in exploring or managing the physiological and ecological processes which underlie resource allocation and plant growth in agroforestry systems. Drawing together a wide range of examples from around the world, the book highlights how recent developments in agroforestry research can contribute to understanding agroforestry system function, and discusses the potential application of agroforestry in addressing a range of land use challenges in both tropical and temperate regions of the world. Including both original research and synthetic analyses, the book presents examples from a wide range of environments. It focuses largely on resource allocation – both above- and below-ground – including an assessment of the recent advances in analytical and modeling tools available to this work.
Topological Data Analysis for Genomics and Evolution : Topology in Biology
Biology has entered the age of Big Data. A technical revolution has transformed the field, and extracting meaningful information from large biological data sets is now a central methodological challenge. Algebraic topology is a well-established branch of pure mathematics that studies qualitative descriptors of the shape of geometric objects. It aims to reduce comparisons of shape to a comparison of algebraic invariants, such as numbers, which are typically easier to work with. Topological data analysis is a rapidly developing subfield that leverages the tools of algebraic topology to provide robust multiscale analysis of data sets. This book introduces the central ideas and techniques of topological data analysis and its specific applications to biology, including the evolution of viruses, bacteria and humans, genomics of cancer, and single cell characterization of developmental processes.
Tooth wear : An authoritative reference for dental professionals and students
This book, now in an extensively revised third edition, is a superbly illustrated and authoritative reference on tooth wear and its management. Tooth wear is becoming an increasing problem as people are living longer and keeping their teeth for longer, with recent UK surveys showing that at least 75% of adults and more than 50% of children now have some form of identifiable tooth wear. This latest edition addresses this growing challenge by describing practical clinical techniques that will aid identification of the aetiological factors responsible for erosion, attrition and abrasion and by offering guidance in the planning and delivery of appropriate patient care.
