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Networks : From Biology to Theory
The concept of a network emerges as a powerful and stimulating research paradigm in mathematics, physics and computer science, and demonstrates a very lively interaction between experimental findings, simulation studies, and theoretical investigations that then in turn lead to new experimental questions. This volume explores this concept in full and features contributions from a truly global set of contributors.
Nanotechnology : Science and Computation
This book offers a unique and authoritative perspective on current research in nanoscale science, engineering and computing. Leading researchers cover the topics of DNA self-assembly in two-dimensional arrays and three-dimensional structures, molecular motors, DNA word design, molecular electronics, gene assembly, surface layer protein assembly, and membrane computing.
Introduction pratique aux bases de données relationnelles = A practical introduction to relational databases
Cet ouvrage introduit le lecteur dans le domaine des bases de données relationnelles en présentant une vaste sélection de sujets portant sur la modélisation des données, les langages de base de données, l'architecture des systèmes et l'évolution post-relationnelle. - Notions fondamentales: le modèle relationnel, les composants d’un système de gestion de bases de données, l’organisation de la mise en œuvre d’une base de données, les tâches de gestion des données. - De l'analyse à la base de données : le modèle entité association, la généralisation et l’agrégation, les dépendances et les formes normales,les contraintes d’intégrité. - Aperçu des langages de requête et de manipulation des données: l’algèbre relationnelle, le calcul des prédicats, SQL, QUEL, QBE, le traitement des valeurs nulles, la protection des données. - Les composants de l'architecture d'un système de bases de données : la compilation, l’interprétation et l’optimisation des requêtes, l’environnement multiutilisateur, le concept de transaction et la sérialisation, les méthodes optimiste et pessimiste, les structures de stockage et les méthodes d’accès. L’intégration et la migration des bases de données: l’exploitation des bases de données hétérogènes, les bases de données sur le Web, les règles de conversion pour effectuer l’intégration et la migration, les variantes de migration des bases de données hétérogènes, la planification de l’intégration et de la migration.
Heterogeneity in statistical genetics : How to assess, address, and account for mixtures in association studies
Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.
Comparative genomics ; RECOMB 2007, International Workshop, RECOMB-CG 2007, San Diego, CA, USA, September 16-18, 2007, Proceedings
This book provides an evolutionary conceptual framework for comparative genomics, with the ultimate objective of understanding the loss and gain of genes during evolution, the interactions among gene products, and the relationship between genotype, phenotype and the environment. The many examples in the book have been carefully chosen from primary research literature based on two criteria: their biological insight and their pedagogical merit. The phylogeny-based comparative methods, involving both continuous and discrete variables, often represent a stumbling block for many students entering the field of comparative genomics. They are numerically illustrated and explained in great detail.
Bioinformatics and Computational Biology Solutions Using R and Bioconductor
Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted in the open source statistical computing environment R. This volume's coverage is broad and ranges across most of the key capabilities of the Bioconductor project, including: Importation and preprocessing of high-throughput data from microarray, proteomic, and flow cytometry platforms / Curation and delivery of biological metadata for use in statistical modeling and interpretation. / Statistical analysis of high-throughput data, including machine learning and visualization,modeling and visualization of graphs and networks. This book is a dynamic document. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Bioarrays : From Basics to Diagnostics
Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections – Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics – that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays.
Advances in Artificial Life ; 9th European Conference, ECAL 2007, Lisbon, Portugal, September 10-14, 2007, Proceedings
This book is organized in topical sections on conceptual articles, morphogenesis and development, robotics and autonomous agents, evolutionary computation and theory, cellular automata, models of biological systems and their applications, ant colony and swarm systems, evolution of communication, simulation of social interactions, self-replication, artificial chemistry, and posters.
Advances in artificial life ; 8th European Conference, ECAL 2005 , Canterbury, UK, September 5-9, 2005, Proceedings
The Artificial Life term appeared more than 20 years ago . Since then the area has developed dramatically, many researchersjoining enthusiastically and research groups sprouting everywhere.a conceptual track, where papers were judged on criteria like importance and/or novelty of the concepts proposed rather than the experimental / theoretical results, has been introduced this year. A conference on a theme as broad as Artificial Life is bound to be very di-verse, but a few tendencies emerged. First, fields like ‘Robotics and Autonomous Agents’ or ‘Evolutionary Computation’are still extremely active and keep onbringing a wealth of results to the A-Life community. Even there, however, new tendencies appear, like collective robotics, and more specifically self-assembling robotics, which represent now a large subsection. Second, new areas appear.‘Morphogenesis and Development’ which used to be the subject of only a fewpapers, is now one of the largest subsections, and seems to be on the brinkof becoming a field of its own. Finally, most classical themes of A-Life re-search like ‘Artificial Chemistry’, ‘Ant-Inspired Systems’, ‘Cellular Automata’,‘Self-Replication’, ‘Social Simulations’ or ‘Bio-realist Simulations’ are still goingstrong and are well represented within this volume.
A Computer Scientists Guide to Cell Biology
Provides a succinct treatment of the general concepts of cell biology, furnishing the computer scientist with the tools necessary to read and understand current literature in the field.After a brief introduction to cell biology, the text focuses on the principles behind the most-widely used experimental procedures and mechanisms, relating them to well-understood concepts in computer science. The presentation of the material has been prepared for the reader’s quick grasp of the topic: comments on nomenclature and background notes can be ascertained at a glance, and essential vocabulary is boldfaced throughout the text for easy identification.
