25 Years of P53 Research
Communication, awareness and access to information: Given the complexity of the field and the fact that data pertaining to ...
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Aids-Associated Viral Oncogenesis
AIDS-associated viral oncology is a significant healthcare problem. Since the identification of human immunodeficiency virus ...
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Application of Apoptosis to Cancer Treatment
This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting ...
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Cancer Drug Resistance
In Cancer Drug Resistance, leading scientists from the best academic institutions and industrial laboratories summarize and ...
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Cell Cycle Regulation
The cell cycle is tightly regulated on many different levels to ensure properly controlled proliferation. Deregulation of ...
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CtBP Family Proteins
The Ctbp family proteins are multifunctional. They predominantly function as transcriptional corepressors in the nucleus ...
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Deoxynucleoside Analogs in Cancer Therapy
Emerging as an important new volume in the renowned Cancer Drug Discovery and Development™ series, Deoxynucleoside Analogs ...
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Genome Instability in Cancer Development
Research over the past decades has firmly established the genetic basis of cancer. In particular, studies on animal tumour ...
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Kaposi Sarcoma Herpesvirus: New Perspectives
Since the identificationof two sequences fromKSHV,wehave learnedmuch about this pathogen as reflected in this book. As it ...
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Molecular Biology of Human Cancers
Over the last three decades, knowledge on the molecular biology of human cancers has vastly expanded. A host of genes and ...
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Molecular Mechanisms of Cancer
Cancer may constitute the most extensively studied functions constitute a second line of defense that disease entity of our ...
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Mouse Models of Human Blood Cancers: Basic Research and Pre-clinical Applications
Although it remains an open question among some people whether mice and humans are similar in disease development, the laboratory ...
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Oncogenes Meet Metabolism : From Deregulated Genes to a Broader Understanding of Tumour Physiology
In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose ...
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The Myc
Intense study of the enigmatic myc proto-oncogene over the last 20 years has broadened our view of its functions and led ...
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The p53 Tumor Suppressor Pathway and Cancer
The current year (2004) marks the Silver Anniversary of the discovery of the p53 tumor suppressor. The emerging ?eld ?rst ...
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Tumor Angiogenesis : Basic Mechanisms and Cancer Therapy
Preface Tumor development and progression occur as a result of cumulative acquisition of genetic alterations affecting oncogenes ...
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