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BioMEMS and biomedical nanotechnology ; Vol. III : Therapeutic Micro/Nanotechnology
The human body is composed of structures organized in a hierarchical fashion: from biomolecules assembled into polymers, to multimeric assemblies such as cellular or-ganelles, to individual cells, to tissues, to organ systems working together in health and disease- each dominated by a characteristic length scale. Decades of science and engineer-ing are now converging to provide tools that enable the orderly manipulation of biological systems at previously inaccessible, though critically important, length scales (<100 mi-crons). Thus, the approaches described in this volume provide a snapshot of how micro-and nanotechnologies can enable the investigation, prevention, and treatment of human disease.The volume is divided into three parts. The first part, Cell-based therapeutics; cov- ers the merger of cells with micro- and anosystems for applications in regenerative medicine spanning the development of novel nanobiomaterials.
BioMEMS and biomedical nanotechnology ; Vol. II : Micro/Nano Technologies for Genomics and Proteomics
Numerous miniaturized DNA microarray, DNA chip, Lab on a Chip and biosensor devices have been developed and commercialized. Such devices are improving the way many impor-tant genomic and proteomic analyses are performed in both research and clinical diagnostic laboratories. The development of these technologies was enabled by a synergistic combina-tion of disciplines that include microfabrication, microfluidics, MEMS, organic chemistry and molecular biology. Some of these new devices and technologies utilize sophisticated mi-crofabrication processes developed by the semiconductor industry.
BioMEMS and Biomedical Nanotechnology : Vol. I: Biological and Biomedical Nanotechnology
Abe Lee has been working on micro/ and nanotechnology for biomedical and biotech applications since 1992. His recent research focuses on the development of integrated micro and nano fluidic chip processors for the following applications: point-of-care diagnostics, "smart" nanomedicine for early detection and treatment, stem cell biology and therapeutics, the synthesis of novel and pure materials, and biosensors to detect environmental and terrorism threats. Jim Lee's research interest includes BioMEMS/NEMS, and polymer micro/nanotechnology. In the last 4 years, he has over 20 refereed journal publications, 2 book chapters, and 5 patents in these areas. He is now leading an NSF Nanoscale Science and Engineering Center for Affordable Nanoengineering of Polymer Biomedical Devices at OSU.
BioMEMS
Here, a new discipline evolved which focuses on microsystems for living systems called "BIOMEMS". In this review at a glance the exciting field of bio-microsystems, from their beginnings to indicators of future successes are presented. It will also show that a broad penetration of micro and nano technologies into biology and medicine will be mandatory for future scientific and new product development progress in life science.
Biology and Control Theory : Current Challenges
Creating some links between control feedback and biology modeling communities based on similarities in modeling, observing and perceiving alive structures, and analyzing interconnections between biological structures and subsystems was the main objective of this volume. The idea of this book was conceived in the context mentioned above with the objective to help in claiming many of the problems for control researchers, starting discussions and opening interactive debates between the control and biology communities, and, finally, to alert graduate students to the many interesting ideas at the frontier between control feedback theory and biology.
Biological Membrane Ion Channels : Dynamics, Structure, and Applications
Ion channels are biological nanotubes that are formed by membrane proteins. Because ion channels regulate all electrical activities in living cells, understanding their mechanisms at a molecular level is a fundamental problem in biology. This book deals with recent breakthroughs in ion-channel research that have been brought about by the combined effort of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these exquisitely designed biomolecules. With chapters by leading experts.
Bio-informatique moléculaire : Une approche algorithmique = Molecular bioinformatics : An algorithmic approach
Deals with genetic maps, from the problem of sequence comparison and alignment, including DNA chips and genomic rearrangement. It thus covers a wide variety of topics relating to algorithmic and combinatorial processing of questions arising from molecular bioinformatics and biotechnology.
Bioinformatics Using Computational Intelligence Paradigms
Bioinformatics as well as Computational Intelligence are undoubtedly remarkably fast growing fields of research and real-world applications with enormous potential for current and future developments. "Bioinformatics using Computational Intelligence Paradigms" contains recent theoretical approaches and guiding applications of biologically inspired information processing systems(Computational Intelligence) against the background of bioinformatics. This carefully edited monograph combines the latest results of Bioinformatics and Computational Intelligence and offers a promising cross-fertilisation and interdisciplinary work between these growing fields.
Bioinformatics and Computational Biology Solutions Using R and Bioconductor
Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted in the open source statistical computing environment R. This volume's coverage is broad and ranges across most of the key capabilities of the Bioconductor project, including: Importation and preprocessing of high-throughput data from microarray, proteomic, and flow cytometry platforms / Curation and delivery of biological metadata for use in statistical modeling and interpretation. / Statistical analysis of high-throughput data, including machine learning and visualization,modeling and visualization of graphs and networks. This book is a dynamic document. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Biogeochemical cycles in globalization and sustainable development
This valuable study of environmental subsystems functioning under various climatic and anthropogenic conditions provides a unique insight into the social context of global changes in biogeochemical cycles and demonstrates current understanding of globalization and sustainable development.
Biofuels, Solar and Wind as Renewable Energy Systems : Benefits and Risks
With shortages of fossil energy, especially oil and natural gas, and heavy biomass energy use occurring in both developed and developing countries, a major focus has developed worldwide on renewable energy systems. Renewable energy systems include wind power, biomass, photovoltaics, hydropower, solar thermal, thermal ponds, and biogas. Currently, a heavy focus is on biofuels made from crops, such as corn, sugarcane, and soybeans, for use as renewable energy sources. Wood and crop residues also are being used as fuel. Though it may seem beneficial to use renewable plant materials for biofuel, the use of crop residues and other biomass for biofuels raises many concerns about major environmental problems, including food shortages and serious destruction of vital soil resources.
Bioethics in Cultural Contexts : Reflections on Methods and Finitude
This book discusses a range of methodological issues for an interdisciplinary bioethics. How can bioethics be an enterprise that does not only isolate issues and moral reasons but also (re)contextualises them? What are the strengths and weaknesses of different traditional and innovative modes of ethical work in terms of these tasks?
Bioethics in a Small World
Bioethics has addressed many of the issues that arise in the context of globalisation. This book presents the results of a conference the Europaische Akademie held in 2003 which developed its thesis in open discussions of foundational and applied problems of bioethics from an interdisciplinary and international perspective.
Bioengineering in cell and tissue research
This book reviews the latest technological developments of bioengineering approaches in cell and tissue research. It is meant to have life and spirit, and to become a pioneer in technology and sciences, especially the life science. The chapters are written by excellent scientists on advanced, frontier technology and address scientific questions that need considerable thinking in terms of engineering.
Bioeconomic modelling and valuation of exploited marine ecosystems
This book offers an environmental-economic analysis of exploited ecosystems with a clear policy orientation. The study tries to move beyond traditional economic fishery analysis in two respects. First, several theoretical and numerical models are offered that combine economic and ecological descriptions of fisheries. These models give special attention to spatial processes as well as to combining exploitation and conservation objectives. Second, valuation and stakeholder concerns are addressed in empirical analyses employing both qualitative and quantitative approaches. The latter is done by using advanced methods of monetary valuation. In addition, the first part of the book presents short, introductory overviews of integrated assessment, economic modeling of fishery management, and incorporating uncertainty in fisheries analysis.
Biodiesel : A realistic fuel alternative for diesel engines
Environmental and political concerns are generating a growing interest in alternative engine fuels such as biodiesel. Biodiesel is a renewable energy source produced from natural oils and fats, which can be used as a substitute for petroleum diesel without the need for diesel engine modification. In addition to being biodegradable and non-toxic, biodiesel is also essentially free of sulfur and aromatics, producing lower exhaust emissions than conventional gasoline whilst providing similar properties in terms of fuel efficiency.
Biochemical Mechanisms of Detoxification in Higher Plants : Basis of Phytoremediation
Plants play a key role in purifying the biosphere of the toxic effects of industrial activity. This book shows how systematic application of the results of investigations into the metabolism of xenobiotics (foreign, often toxic substances) in plants could make a vastly increased contribution to planetary well-being. Deep physiological knowledge gained from an accumulation of experimental data enables the great differences between the detoxifying abilities of different plants for compounds of different chemical nature to be optimally exploited. Hence planting could be far more systematically adapted to actual environmental needs than is actually the case at present.
Bioarrays : From Basics to Diagnostics
Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections – Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics – that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA, proteins, antibodies, and carbohydrate arrays.
Bioactive Molecules and Medicinal Plants
Use of medicinal plants is as old as human civilization and continuous efforts are being made to improve medicinal plants or produce their products in high amounts through various technologies. About 200,000 natural products of plant origin are known and many more are being identifed from higher plants and microorganisms. Some plant-based drugs have been used for centuries and there is no alternative medicine for many drugs, such as cardiac glycosides. However, natural products research was sidelined to pave the way for com- natorial chemistry, which was expected to produce large numbers of synthetic compounds for high-throughput screening (HTS). This line of work has failed to deliver desirable results. Moreover, it is not possible for all pharmaceutical companies and institutions to adopt costly HTS technology. Therefore, medi- nal plants and their bioactive molecules are always in demand and are a central point of research. While planning this book, we endeavored to incorporate - ticles that cover the entire gamut of current medicinal plants research.
Bioactive Marine Natural Products
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R&D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.
