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Bioactive Marine Natural Products
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R&D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.
Bioactive Heterocyles I
Bioactive Heterocycles I is a continuation of critical accounts about heterocyclic compounds within the series Topics in Heterocyclic Chemistry. The present volume provides comprehensive reviews of the chemistry and bioactivity of selected groups of heterocycles and natural products. … Overall, this book covers in detail several classes of bioactive heterocyclic compounds including selected natural products. The focus is on the most recent advances, and the clarity of the presentation is very good. It should be of interest to individuals interested in the discovery and synthesis of bioactive small molecules, including research scientists in academia and industry.
Bioactive Heterocycles V
This volume contains 10 chapters. The contributions are from researchers famous in their respective fields and the chapters contain high quality reviews on topics related to the chemo-biological studies of several different heterocyclic groups. The first chapter from Saracoglu reviews the functionalization of indoles and the pyrroles via Michael additions, as these compounds have potential for their biological activities. In second chapter Men ́endez reviews the chemistry of the welwitindolinones. Topcu and Demirkiran, in the third chapter, describe the chemistry and biological studies of lignans from Taxus species, including their biosynthesis and recent strategies for the synthesis of lignans.
Beyond Kyoto : A new global climate certificate system : Continuing Kyoto commitsments or a global ´Cap and Trade´ scheme for a sustainable climate policy?
This book shows how humankind can ‘prevent dangerous interference with the c- mate system’ without dangerous interference with the global economic system. In the two underlying studies on behalf of the Ministry of Environment and Transport of i the German federal state of Baden-Württemberg, the results have been elaborated through scientific evaluation of different climate protection systems and intensive developmental work on an efficient climate protection system. The results will be presented in nine chapters according to the following nine basic R&D steps: 1. Quantifying the ‘ultimate climate objective’ of the world community in order ‘to prevent dangerous interference with the climate system,’ thus achieving climate sustainability; 2. Development of a comprehensive standard system for evaluating the prospect of success for different climate protection systems; 3. Based on this scientific standard system, evaluation of the current Kyoto system and of the most important proposals for ‘incremental regime evolution’ of the Kyoto system. Unfortunately, it must be noted that these systems are incapable of achi- ing climate sustainability; 4. Evaluating three proposals for ‘structural regime change’ of the Kyoto system. Following this objective evaluation process and numeric comparison of the diff- ent proposals, 5. Description of the eight basic elements of GCCS and its in-depth ‘critical asse- ment;’ 6.
Beam Instrumentation and Diagnostics
This treatise covers all aspects of the design and the daily operations of a beam diagnostic system for a large particle accelerator. A very interdisciplinary field, it involves contributions from physicists, electrical and mechanical engineers and computer experts alike so as to satisfy the ever-increasing demands for beam parameter variability for a vast range of operation modi and particles. The author draws upon 40 years of research and work, most of them spent as the head of the beam diagnostics group at GSI. He has illustrated the more theoretical aspects with many real-life examples that will provide beam instrumentation designers with ideas and tools for their work.
Bayesian reliability
Bayesian Reliability presents modern methods and techniques for analyzing reliability data from a Bayesian perspective. The adoption and application of Bayesian methods in virtually all branches of science and engineering have significantly increased over the past few decades. This increase is largely due to advances in simulation-based computational tools for implementing Bayesian methods. The authors extensively use such tools throughout this book, focusing on assessing the reliability of components and systems with particular attention to hierarchical models and models incorporating explanatory variables. Such models include failure time regression models, accelerated testing models, and degradation models. The authors pay special attention to Bayesian goodness-of-fit testing, model validation, reliability test design, and assurance test planning. Throughout the book, the authors use Markov chain Monte Carlo (MCMC) algorithms for implementing Bayesian analyses--algorithms that make the Bayesian approach to reliability computationally feasible and conceptually straightforward.
Battery management systems : Accurate state-of-charge indication for battery-powered applications
Builds further on the contents of the first volume in the Philips Research Book Series, Battery Management Systems - Design by Modelling. Since the subject of battery SoC indication requires a number of disciplines, this book covers all important disciplines starting from (electro)chemistry to understand battery behaviour, via mathematics to enable modelling of the observed battery behaviour and measurement science to enable accurate measurement of battery variables and assessment of the overall accuracy, to electrical engineering to enable an efficient implementation of the developed SoC indication system. It will therefore serve as an important source of information for any person working in engineering and involved in battery management.
Basic Algebra
Basic Algebra and Advanced Algebra systematically develop concepts and tools in algebra that are vital to every mathematician, whether pure or applied, aspiring or established. Together, the two books give the reader a global view of algebra and its role in mathematics as a whole.Basic Algebra presents the subject matter in a forward-looking way that takes into account its historical development. It is suitable as a text in a two-semester advanced undergraduate or first-year graduate sequence in algebra, possibly supplemented by some material from Advanced Algebra at the graduate level. It requires of the reader only familiarity with matrix algebra, an understanding of the geometry and reduction of linear equations, and an acquaintance with proofs.
Axions : Theory, Cosmology, and Experimental Searches
Axions are peculiar hypothetical particles that could both solve the CP problem of quantum chromodynamics and at the same time account for the dark matter of the universe. Based on a series of lectures by world experts in this field held at CERN (Geneva), this volume provides a pedagogical introduction to the theory, cosmology and astrophysics of these fascinating particles and gives an up-to-date account of the status and prospect of ongoing and planned experimental searches. Learners and practitioners of astroparticle physics will find in this book both a concise introduction and a current reference work to a showcase topic that connects the "inner space" of the elementary particle world with the "outer space" of the universe at large.
Autonomous Robots and Agents
This book deals with the theoretical and methodological aspects of incorporating intelligence in Autonomous Robots and Agents. Challenges faced in the real world to accomplish complex tasks, which require collaborative efforts, and methods to overcome them, are detailed. Several informative articles deal with navigation, localization and mapping of mobile robots, a problem that engineers and researchers are grappling with all the time.This edited volume is targeted to present the latest state-of-the-art methodologies in Robotics. It is a compilation of the extended versions of the very best papers selected from the many that were presented at the 3rd International Conference on Autonomous Robots and Agents (ICARA 2006) which was held at Palmerston North, New Zealand from 11-14 December, 2006. Scientists and engineers who work with mobile robots will find this book very useful and stimulating.
Automotive Lighting and Human Vision
Visual perception is the most important of the human senses. Lack of visual perception is one of the main causes of accidents. The safety of vehicle traffic depends on how well automotive lighting supports the visual perception of the driver. This book explains the fundamentals of visual perception, like e.g. physiology of eye and brain, as well as those of automotive lighting technology, like e.g. design of headlamps and signal lights. It is an interdiciplinary approach to a fastly evolving field of science and technology, answering questions like "How does information enter our brain when driving a car?" and "What are the benefits and dangers of LED signal lighting?"
Authoritative communities : The scientific case for nurturing the whole child
Authoritative Communities: The Scientific Case for Nurturing the Whole Child introduces innovative solutions based firmly in the children’s mental health and resilience literature and in the hypothesis that humans are "hardwired to connect." These "authoritative communities" consist of such individuals and institutions as parents, teachers, coaches, elders, and a variety of organizations that are committed to each other’s well-being over the long-term and who instill children with prosocial values such as empathy and compassion. Living within these communities enables children and youth to develop a consistent sense of purpose and meaning, so that they, in turn, are able to grow up to be responsible, productive, and nurturing adults.
Attitudes and changing contexts
In this book, the author defends a unified externalists account of propositional attitudes and reference, and formalizes this view within possible world semantics.
Atomistic approaches in modern biology : From quantum chemistry to molecular simulations
This volume of Topics in Current Chemistry presents an overview of atomistic theoreticalmethodsapplied tomolecular biologicalsystems. Itthus repesents abottom-upview of chemistryonbiologyfroma theoreticalperspective. The chapters arearrangedsuchthat important issuesareconsidered startingfrom a quantum mechanical perspective and proceeding to a molecular mechanics and molecular dynamics descriptiono fthemotionoftheelementaryparticles involved.which are responsible for the properties and function of biomolecules. Depending on the length and time scales relevant for a given phenomenon to be investigated, tailored theoretical methods are required to account for these. If one is interested in large scale motions of molecules, a molecul- mechnanics-based description willbeappropriate.
Atomic spectroscopy : Introduction to the theory of hyperfine structure
Atomic Spectroscopy provides a comprehensive discussion on the general approach to the theory of atomic spectra, based on the use of the Lagrangian canonical formalism. This approach is developed and applied to explain the hydrogenic hyperfine structure associated with the nucleus motion, its finite mass, and spin. The non-relativistic or relativistic, spin or spin-free particle approximations can be used as a starting point of general approach. The special attention is paid to the theory of Lamb shift formation. The formulae for hydrogenic spectrum including the account of Lamb shift are written in simple analytical form. The book is of interest to specialists, graduate and postgraduate students, who are involved into the experimental and theoretical research in the field of modern atomic spectroscopy.
Atomic and Nuclear Analytical Methods : XRF, Mössbauer, XPS, NAA and Ion-Beam Spectroscopic Techniques
This book is a blend of analytical methods based on the phenomenon of atomic and nuclear physics. It comprises comprehensive presentations about X-ray Fluorescence (XRF), Mössbauer Spectroscopy (MS), X-ray Photoelectron Spectroscopy (XPS), Neutron- Activation Analysis (NAA), Particle Induced X-ray Emission Analysis (PIXE), Rutherford Backscattering Analysis (RBS), Elastic Recoil Detection (ERD), Nuclear Reaction Analysis (NRA), Particle Induced Gamma-ray Emission Analysis (PIGE), and Accelerator Mass Spectrometry (AMS). These techniques are commonly applied in the fields of medicine, biology, environmental studies, archaeology or geology et al. and pursued in major international research laboratories.
Atmosphere and Climate : Studies by Occultation Methods
In this book we focus on sensors on Low Earth Orbit (LEO) satellites, which exploit solar, lunar, stellar, GNSS (Global Navi- tion Satellite Systems), and LEO-crosslink signals for observing the Earth's - mosphere and climate. The methods all share the key properties of self-calibration, high accuracy and vertical resolution, global coverage, and (if using radio signals) all-weather ca- bility. The atmospheric parameters obtained extend from the fundamental va- ables temperature, density, pressure and water vapor via trace gases, aerosols and cloud liquid water to ionospheric electron density. Occultation data are therefore of high value in a wide range of fields including climate monitoring and research, atmospheric physics and chemistry, operational meteorology, and ionospheric physics.
Astrophysics : A new approach
For a quantitative understanding of the physics of the universe - from the solar system through the milky way to clusters of galaxies all the way to cosmology - these edited lecture notes are perhaps among the most concise and also among the most critical ones: Astrophysics has not yet stood the redundancy test of laboratory physics, hence should be wary of early interpretations. Special chapters are devoted to magnetic and radiation processes, supernovae, disks, black-hole candidacy, bipolar flows, cosmic rays, gamma-ray bursts, image distortions, and special sources. At the same time, planet earth is viewed as the arena for life, with plants and animals having evolved to homo sapiens during cosmic time. -- This text is unique in covering the basic qualitative and quantitative tools, formulae as well as numbers, needed for the precise interpretation of frontline phenomena in astrophysical research. The author compares mainstream interpretations with new and even controversial ones he wishes to emphasize.
Astrophysical disks : Collective and stochastic phenomena
The book deals with collective and stochastic processes in astrophysical discs involving theory, observations, and the results of modelling. Among others, it examines the spiral-vortex structure in galactic and accretion disks , stochastic and ordered structures in the developed turbulence. It also describes sources of turbulence in the accretion disks, internal structure of disk in the vicinity of a black hole, numerical modelling of Be envelopes in binaries, gaseous disks in spiral galaxies with shock waves formation, observation of accretion disks in a binary system and mass distribution of luminous matter in disk galaxies.
Assessment of climate change for the Baltic Sea Basin
Offers an up-to-date overview of the latest scientific findings in regional climate research on the Baltic Sea basin. This includes climate changes in the recent past, climate projections up until 2100 using the most sophisticated regional climate models available, and an assessment of climate change impacts on terrestrial, freshwater and marine ecosystems.
