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Association Mapping in Plants
For the past decade, there has been success in using conventional map-based strategies in identification and cloning of quantitative trait loci (QTL) in model plant species including tomato and Arabidopsis. These quantitative traits are generally the products of many loci with varying degrees of effect upon the observed phenotypes. Recently, a new approach to genetic mapping has emerged called association mapping. This new technique takes into account the thousands of genes to evaluate for QTL effect and is a more efficient approach that does not require generation of segregating populations/large numbers of progeny. As it can utilize all of the historic recombination events in a diverse population of individuals it can generate higher resolution genetic maps and, is needed to complement current map based cloning methods.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
Aquaculture in the Ecosystem
This book provides a scientific forecast of the development in aquaculture with a focus on the environmental, technological, social and economic constraints that need to be resolved to ensure sustainable development of the industry and allow the industry to be able to feed healthy seafood products to the future generations. The chapters included discuss the most critical bottlenecks of the development encompassing subjects of understanding the environmental impacts, the current state-of-art in monitoring programs and in coastal zone management, the important interactions between wild and cultured organisms including release of non-native species into the wild, the current trends within the development of aquafeeds along with human health aspects as well as the political, socio-economic and economic trends within the industry including a chapter on approaches taken by Non Governmental Organisations (NGOs) to aquaculture. Finally the last chapter provides different future scenarios of the industry based on the identified bottlenecks.
Applications of Plant Metabolic Engineering
Written by leading international experts in the field of plant metabolic engineering, this book discusses, mainly, applications of plant metabolic engineering. Metabolic engineering, which is part of second generation biotechnology, has made several contributions at basic level as well as at conceptualising products ever since its emergence in the early 1980s. Applications resulting from metabolic engineering are expected to play a very important role in future for plant breeding, e.g. for improved resistance or improved traits concerning health promoting constituents, and production of fine chemicals such as medicines, flavors and fragrances.
Alkaliphiles : Genetic properties and applications of enzymes
The pioneering work of Dr. Koki Horikoshi on the discovery, research and applications of alkaliphilic bacteria are described here in their entirety. The isolation, distribution and taxonomy of alkaliphilic microorganisms as well as their cell structure and physiology are discussed for a basic understanding of these entities. The molecular biology and genome sequencing of some alkaliphilic bacterial strains are also presented. Part II of the volume focuses on enzymes of alkaliphiles and their applications. These include alkaline proteases, starch-degrading enzymes and numerous others. Some of these enzymes are currently in wide commercial use as laundry detergent additives and in wastewater treatment. Alkaliphiles are a relatively recent field of research that will no doubt provide avenues to a wide range of further discoveries and applications for a new generation of workers in bioscience and technology.
Abiotic Stress Tolerance in Plants : Toward the Improvement of Global Environment and Food
Stresses in plants caused by salt, drought, temperature, oxygen, and toxic compounds are the principal reason for reduction in crop yield. For example, high salinity in soils accounts for large decline in the yield of a wide variety of crops world over; ~1000 million ha of land is affected by soil salinity. Increased sunlight leads to the generation of reactive oxygen species, which damage the plant cells. The threat of global environment change makes it increasingly demanding to generate crop plants that could withstand such harsh conditions. Much progress has been made in the identification and characterization of the mechanisms that allow plants to tolerate abiotic stresses.
Iterated Function Systems for Real-Time Image Synthesis
Natural phenomena can be visually described with fractal-geometry methods, where iterative procedures rather than equations are used to model objects. With the development of better modelling algorithms, the efficiency of rendering, the realism of computer-generated scenes and the interactivity of visual stimuli are reaching astonishing levels. Iterated Function Systems for Real-Time Image Synthesis gives an explanation of iterated function systems and how to use them in generation of complex objects.
Component-Based Software Development for Embedded Systems : An Overview of Current Research Trends
Embedded systems are ubiquitous. They appear in cell phones, microwave ovens, refrigerators, consumer electronics, cars, and jets. Some of these embedded s- tems are safety- or security-critical such as in medical equipment, nuclear plants, and X-by-wire control systems in naval, ground and aerospace transportation - hicles. With the continuing shift from hardware to software, embedded systems are increasingly dominated by embedded software. Embedded software is complex. Its engineering inherently involves a mul- disciplinary interplay with the physics of the embedding system or environment. Embedded software also comes in ever larger quantity and diversity. The next generation of premium automobiles will carry around one gigabyte of binary code. The proposed US DDX submarine is e?ectively a ?oating embedded so- ware system, comprising 30 billion lines of code written in over 100 programming languages. Embedded software is expensive. Cost estimates are quoted at around US$15– 30 per line (from commencement to shipping). In the defense realm, costs can range up to $100, while for highly critical applications, such as the Space Shuttle, the cost per line approximates $1,000. In view of the exponential increase in complexity, the projected costs of future embedded software are staggering.
Biometric User Authentication for IT Security : From Fundamentals to Handwriting
Biometric User Authentication for IT Security: From Fundamentals to Handwriting conveys general principals of passive (physiological trait like fingerprint, iris, face) and active (learned and trained behavior like voice, handwriting and gait) biometric recognition techniques to the reader. This professional book, unlike other publications in this area which concentrate on passive schemes, reflects a more comprehensive analysis of one particular active biometric technique: handwriting. Aspects which are thoroughly discussed include sensor characteristic dependency, attack scenarios, and the generation of cryptographic keys from handwriting.
Beginning Web Development, Silverlight, and ASP.NET AJAX : From novice to professional
Beginning Web Development, Silverlight, and ASP.NET AJAX: From Novice to Professional aims to give you the skills you need to start building web applications with Microsoft's next–generation technology as quickly as possible. Whether you're interested in ASP.NET AJAX, Silverlight, or the technologies that support them (WPF, WCF, WF, etc.), this book is the starting point that you need. It adopts a “zero to hero” approach that concentrates on achieving practical results you can use in real projects rather than presenting a deep academic treatment that can't be immediately applied.
Beginning Apache Struts: From novice to professional
Beginning Apache Struts will provide you a working knowledge of Apache Struts 1.2. This book is ideal for you Java programmers who have some JSP familiarity, but little or no prior experience with Servlet technology. Organized in a condensed tutorial and lab format, the material in this book has been tested in real classroom environments. It takes a step-by-step, hands-on approach to teaching you Struts. The book even previews the next generation of Struts, the Apache Shale. The overall result is that you can quickly apply Struts to your work settings with confidence.
Beginning Ajax with PHP : From novice to professional
Beginning Ajax with PHP: From Novice to Professional is the first book to introduce how these two popular technologies can work together to create next-generation applications. Author Lee Babin covers what you commonly encounter in daily web application development tasks.
Assistive technologies, robotics, and automated machines in the health domain
The field of healthcare is constantly evolving and advancing with new technologies and innovations. Among these, assistive technologies, robotics, and automated machines are rapidly gaining ground as powerful tools to improve the quality of care and enhance patient outcomes. From wearable devices that monitor vital signs to surgical robots that assist in complex procedures, these technologies have the potential to revolutionize the way we deliver healthcare. The development and the integration of assistive technologies, care robots, and automated machines are strategic both as single components, when paired together, and when interconnected in the health domain.This reprint explores the latest developments in assistive technologies, robotics, and automated machines in the health domain, providing a comprehensive overview of their applications and potential impact. The reprint is for the benefit of healthcare professionals, researchers, engineers, and students interested in these rapidly evolving fields.
Artificial intelligence-based Internet of things systems
Discusses the evolution of future generation technologies through Internet of Things (IoT) in the scope of Artificial Intelligence (AI). The main focus of this volume is to bring all the related technologies in a single platform, so that undergraduate and postgraduate students, researchers, academicians, and industry people can easily understand the AI algorithms, machine learning algorithms, and learning analytics in IoT-enabled technologies. This book uses data and network engineering and intelligent decision support system-by-design principles to design a reliable AI-enabled IoT ecosystem and to implement cyber-physical pervasive infrastructure solutions. This book brings together some of the top IoT-enabled AI experts throughout the world who contribute their knowledge regarding different IoT-based technology aspects. Addresses the complete functional framework workflow in AI-enabled IoT ecosystem; Presents intelligent object identification and object discovery through the IoT ecosystem and its implications to the real world ;Explores security and privacy issues and trustworthy machine learning related to data-intensive technologies in AI-based IoT ecosystems.
Ajax Patterns and Best Practices
Ajax is taking us into the next generation of web applications. Ajax has broken the client-server barrier by decoupling the client from the server, but an Ajax application still needs a server to extract content from. The most effective use of Ajax and the server requires an understanding of REST, an architectural style used to define Web services. Ajax Patterns and Best Practices explores dynamic web applications that combine Ajax and REST as a single solution. A major advantage of REST is that, like Ajax, it can be used with today's existing technologies.
Advances in optical fiber communications
Given the increasing importance of a globally interconnected world, driven by modern digital services and the need for fast and reliable access to digital resources, communication networks are one of the key infrastructures in today’s society. In this scenario, fiber optics and optical devices play a leading role, as they allow for unprecedented growth in our capacity to cope with the ever-increasing traffic demand. Optical transmission solutions range from high-speed networks based on coherent detection and advanced modulation formats for long-haul-level communications, to networks still relying on traditional intensity modulation and direct detection receivers for short-reach communications, down to intra-data center scenarios.
Advanced technique and future perspective for next generation optical fiber communications
Optical fiber communication industry has gained unprecedented opportunities and achieved rapid progress in recent years. However, with the increase of data transmission volume and the enhancement of transmission demand, the optical communication field still needs to be upgraded to better meet the challenges in the future development. Artificial intelligence technology in optical communication and optical network is still in its infancy, but the existing achievements show great application potential. In the future, with the further development of artificial intelligence technology, AI algorithms combining channel characteristics and physical properties will shine in optical communication. This reprint introduces some recent advances in optical fiber communication and optical network, and provides alternative directions for the development of the next generation optical fiber communication technology.
Advanced mathematical science for mobility society
The automotive industry has made steady progress in technological innovations under the names of Connected Autonomous-Shared-Electric (CASE) and Mobility as a Service (MaaS). Needless to say, mathematics and informatics are important to support such innovations. As the concept of cars and movement itself is diversifying, they are indispensable for grasping the essence of the future mobility society and building the foundation for the next generation. This book contains three main contents. 1. Mathematical models of flow 2. Mathematical methodsfor huge data and network analysis 3. Algorithm for mobility society The first one discusses mathematical models of pedestrian and traffic flow, as they are important for preventing accidents and achieving efficient transportation.
Advanced machine learning and deep learning approaches for remote sensing
Provides research on how technologies such as artificial intelligence-based machine learning and deep learning can be applied to remote sensing. Through this, we can see the process of solving the existing problems of image and image signal processing for remote sensing. These techniques are computationally intensive and require the help of high-performance computing devices. With the development of devices such as GPUs, remote sensing technology, and aerial sensing technology, it is possible to monitor the Earth with high-resolution images and to obtain vast amounts of Earth observation data. The papers published in this reprint describe recent advances in big data processing and artificial intelligence-based technologies for remote sensing technology.
