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A Time for Metabolism and Hormones
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
A Sea Change: The Exclusive Economic Zone and Governance Institutions for Living Marine Resources
A Sea Change in a Changing Sea The oceans, seas and coastal areas encompass over 70% of the earth’s surface. They are a critical driver of the earth’s hydrologic cycle and climate system, important for c- merce, transport, and tourism, a source of economically important living marine resources, minerals such as hydrocarbons, as well as new pharmaceutical compounds. The marine environment provides essential habitats for thousands of marine living 1 2 resources, which in turn contribute significantly to global food security, employment, 3 and trade. Overall, the sea’s contribution to human welfare, in terms of market and non-market resources and environmental services, has been estimated at US$21 trillion/year (Costanza, 2000). However, despite the importance of the ocean realm to humans, there is a growing sense that human impacts are destabilizing this system. Some experts believe that current fishing levels are approaching or exceeding the total 4 productivity of the ocean ecosystem (National Research Council, 1999).
A Personal History of Nuclear Medicine
In A Personal History of Nuclear Medicine, Dr. Henry N. Wagner, Jr. outlines his significant contribution to the field of nuclear medicine over the past half-century, while also discussing the hurdles that the field faced in becoming a major component of modern medical practice. Further, the author explores challenges within the academic and medical establishments, which have often been known for resisting change
A History of Radionuclide Studies in the UK : 50th Anniversary of the British Nuclear Medicine Society
The British Nuclear Medicine Society celebrates its 50th Anniversary with this booklet, which reflects the research of many of the pioneers in the use of radionuclides for the diagnosis and therapy of human disease. Since 1949 there have been remarkable advances in radionuclide techniques and imaging equipment: from the first devices “home-made” in the many physics departments throughout the UK, to the sophisticated multimodality imagers now in everyday use in Nuclear Medicine. The BNMS has been instrumental in promoting the use of radionuclide techniques in the investigation of pathology by supporting and providing education, research and guidelines on the optimum use of radiation to help patients.
A History of Plastic Surgery
Te frst section deals with anatomy and the healing of wounds, discusses You have in your hands a work that should become a old and new plastic surgical procedures, and outlines the milestone of our understanding of medical history. In it history of anaesthesia. Te second covers the methods Professor Paolo Santoni-Rugiu and Mr Philip Sykes trace used from ancient times to reconstruct various areas of the development of plastic surgery and much of medi- the body and is the most extensive. Te last section d- cine in general, over three millennia. With his extensive cusses the history of cosmetic surgery and the origin of knowledge of clinical plastic surgery, no one could be present day procedures. better placed than the senior author to gather this valu- Te pages ring with the names of giants of the medical able material from historical documents.
A History of Limb Amputation
This book traces humanity’s long experience of natural amputations due to congenital absence, disease, frostbite, toxins, domestic and wild animal trauma, and for non-medical reasons related to punitive, ritual, and legal actions, ultimately leading to the development of elective surgical amputation. While the evolution of surgical techniques forms a major chapter in the book, many ancillary problems are addressed including the control of hemorrhage and infection, the approach to pain relief, the development of suitable instruments and equipment, and the invention of prostheses, all suitably illuminated with case histories and relevant illustrations. In addition, alternative procedures designed to avoid amputation, increasingly important in the last two centuries, are debated, and factors associated with self-amputation in extremis, not rare according to press reports, are also examined. A separate chapter considers the philosophy and interpretations of society, patients, and surgeons faced with amputation, particularly before anesthesia.
A History of Atmospheric CO2 and Its Effects on Plants, Animals, and Ecosystems
The authors address the future role of atmospheric CO2 and its likely effects on ecosystems. This book incorporates the advances of various earth science, environmental, and ecological fields into an overall account of global change and the changing dynamics of life on Earth.
A Closer Look at Antibiotic Resistance
Bacterial infections have become more difficult, and sometimes impossible, to treat due to antibiotic resistance, which occurs when bacteria develop the ability to defeat the available drugs designed to kill them. According to the Centers for Disease Control and Prevention, each year, 2 million Americans become sick with antibiotic-resistant infections, and of that, about 23,000 die. This book examines the challenges related to antibiotic resistance, the development and use of diagnostic testing to identify antibiotic resistance, the development of treatments for resistant infections, and appropriate antibiotic use.
A Changing World : Challenges for Landscape Research
Written primarily for researchers and advanced students in environmental and social sciences, this latest book in Springer’s Landscape Series looks at some of the emerging fields and new challenges in landscape research. These include: the role of value systems in perceiving, appreciating, and managing landscapes the ‘space’ and ‘place’ concept in landscape research GIS and remote sensing techniques for gathering and processing spatially and temporally explicit land cover, vegetation, and land use data methods of landscape history landscape genetics and genetic methods to test landscape connectivity and dispersal of plant and animal species
3D printing of pharmaceutical and drug delivery devices progress from bench to bedside
Discover the latest, fast-developing technology to help move towards more cost-effective, small-batch, decentralized manufacturing of personalized systems . 3D printing has revolutionized manufacturing. Its precision and flexibility have enabled the large-scale production of materials and devices too complex for conventional industrial manufacturing. This has been particularly revolutionary in the field of pharmaceutical production, where 3D printing is being integrated into the manufacture of both drugs and drug delivery devices. It has never been more important for industry professionals to understand this form of production.
3D cell culture : Methods and protocols
Expands on the previous edition with discussions about the latest organoid models developed for many more organs; new hydrogels and devices for 3D culture; and the organoid systems that have been improved by incorporating more components of tissue microenvironments in the in vitro culture. The chapters in this book are organized into five parts and cover topics such as biofabrication, organoids, microfluidic systems, bioprinting, and image analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Law, Humanities and the COVID Crisis
Seeks to address the immediacy of COVID-19 by focusing on the implications of the virus in a wider interdisciplinary context Law, Humanities and the COVID Crisis</i> sets out a framework for understanding the COVID-19 virus beyond its epidemiological constraints, asking us to question the very definition of what it means to be human. Researchers from around the world offer their critical reflections on the past, present, and future of this period of sociocultural upheaval and the tremendous suffering that has laid bare fundamental imbalances in our society.
Law and Justice in a globalized world
Consists of a selection of papers presented at the Asia-Pacific Research Conference on Social Sciences and Humanities. It contains essays on current legal issues in law and justice, and their role and transformation in a globalizing world. Topics covered include human rights, criminal law, law of the sea, good governance, democracy, foreign investment, and regional integration. The conference focused on Asia and the Pacific, two regions where law has taken an important position in creating and shaping the regional integrations, new legal institutions, and norms.
Land law : Text, cases, and materials
Covering all core aspects of land law including legal estates, legal interests, equitable interests, interests in the home, leases, easements, covenants and security interests in land, the book provides students with the detailed knowledge and analytical tools required to understand and engage fully with the current topical debates surrounding the subject.
Judges and Adjudication in Constitutional Democracies : A View from Legal Realism
Offers contributions to a philosophical and realistic approach to the place of adjudication in contemporary constitutional democracies. Bringing together scholars from different legal and philosophical backgrounds, purports to cast light on the role(s) of judges and the function of judicial interpretation inside of constitutional states, from the standpoint of legal realism as a revisited and sophisticated jurisprudential outlook. In so doing, also copes with a few major jurisprudential issues, like, e.g., determining the ideas that make up the core of legal realism, exploring the relation between legal realism and legal positivism, identifying the boundaries of judicial interpretation as they appear from a realist standpoint, as well as considering some skeptical outlooks on the very claims of contemporary legal realism.
Competition Authorities in South Eastern Europe : Building Institutions in Emerging Markets
Provides answers to key open questions concerning competition policy in emerging economies, with a focus on South Eastern Europe. The contributions address two major issues. One is the design of competition policy and the national competition authorities that enforce it, including the topics of competition advocacy and state aid control; the other is the use of economic methods in competition law enforcement, especially in the cases of relevant market definition and merger control. Many lessons learned in the countries of South Eastern Europe can be applied to the emerging markets of other regions. As such, the findings presented here will be highly relevant for officials and staff at national competition authorities, advisers to legislators shaping national competition policy, competition law professionals, and university students alike.
Common Law, Civil Law, and Colonial Law : Essays in Comparative Legal History from the Twelfth to the Twentieth Centuries
This volume is a selection of essays taken from the excellent range of papers presented at the British Legal History Conference hosted by the Institute for Legal and Constitutional Research at the University of St Andrews, 10-13 July 2019. The theme of the conference gives this book its title: 'comparative legal history'. The topic came easily to the organisers because of their association with the St Andrews-based European Research Council Advanced grant project 'Civil law, common law, customary law: consonance, divergence and transformation in Western Europe from the late eleventh to the thirteenth centuries'.
China and the World in a Changing Context : Perspectives from Ambassadors to China
This book aims to present an overview of China and the world from diverse angles. It brings together essays by ambassadors to China on a range of bilateral and multilateral issues, including trade and investment, regional economic cooperation, sustainable development, technology and innovation, and entrepreneurship. Given their familiarity with China and extensive international experience, the insights of these ambassadors are useful for policymakers, academics, entrepreneurs, students, and anyone trying to make sense of our rapidly changing world.
Child soldiers and the defence of duress under International criminal law
Investigates the use of duress as a defence in international criminal law, specifically in cases of child soldiers. The prosecution of children for international crimes often only focuses on whether children can and should be prosecuted under international law. However, it is rarely considered what would happen to these children at the trial stage. This work offers a nuanced approach towards international prosecution and considers how children could be implicated and defended in international courts.
Capital Punishment and the Criminal Corpse in Scotland, 1740–1834
This book provides the most in-depth study of capital punishment in Scotland between the mid-eighteenth and early nineteenth century to date. Based upon an extensive gathering and analysis of previously untapped resources, it takes the reader on a journey from the courtrooms of Scotland to the theatre of the gallows. It introduces them to several of the malefactors who faced the hangman’s noose and explores the traditional hallmarks of the spectacle of the scaffold. It demonstrates that the period between 1740 and 1834 was one of discussion, debate and fundamental change in the use of the death sentence and how it was staged in practice. In addition, the study provides an innovative investigation of the post-mortem punishment of the criminal corpse. It offers the reader an insight into the scene at the foot of the gibbets from which criminal bodies were displayed, and around the dissection tables of Scotland’s main universities where criminal bodies were used as cadavers for anatomical demonstration. In doing so it reveals an intermediate stage in the long-term disappearance of public bodily punishment.
