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Anthracycline Chemistry and Biology II : Mode of Action, Clinical Aspects and New Drugs
This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts. The series is still valid and useful after five or ten years. More information as well as the electronic version of the whole content is available at: springerlink.com.
Anthracycline Chemistry and Biology I : Biological Occurence and Biosynthesis, Synthesis and Chemistry
"This book … covers many different aspects of the origin, chemistry, and biosynthesis of one of the oldest but most important classes of anticancer agents. … In summary, the book is nicely produced, very well edited, and should serve as a valuable source of information … . This book will serve as an inspiration for scientists and students in the areas of chemistry, drug discovery, and biological evaluation. It should be an essential addition to institutional library collections … ."
Antarctica : Contributions to Global Earth Sciences
Sixty articles arranged in eight thematic sections refer to most recent geological and geophysical results of Antarctic research. The Precambrian of the East Antarctic shield and its geological history is considered as well as sub-ice topography, geophysics and stratigraphy, sedimentology and geophysics of the surrounding Southern Ocean. Particular emphasis is given to the connection of the Antarctic and the surrounding continents when forming part of Gondwana.
Animals in space : From research rockets to the space shuttle
Animals in Space will explain why dogs, primates, mice and other rodents were chosen and tested, at a time when dedicated scientists from both space nations were determined to establish the survivability of human subjects on both ballistic and orbital space flights. It will also recount the way this happened; the secrecy involved and the methods employed, and offer an objective analysis of how the role of animals as spaceflight test subjects not only evolved, but subsequently changed over the years in response to a public outcry led by animal activists. It will explore the ways in which animal high-altitude and space flight research impacted on space flight biomedicine and technology, and how the results - both successful and disappointing - allowed human beings to then undertake that same hazardous journey with far greater understanding and confidence.
Animals in Our Midst : The Challenges of Co-existing with Animals in the Anthropocene
This book brings together authoritative voices in animal and environmental ethics, who address the many different facets of changing human-animal relationships in the Anthropocene. As we are living in complex times, the issue of how to establish meaningful relationships with other animals under Anthropocene conditions needs to be approached from a multitude of angles. This book offers the reader insight into the different discussions that exist around the topics of how we should understand animal agency, how we could take animal agency seriously in farms, urban areas and the wild, and what technologies are appropriate and morally desirable to use regarding animals. This book is of interest to both animal studies scholars and environmental ethics scholars, as well as to practitioners working with animals, such as wildlife managers, zookeepers, and conservation biologists.
Animal Welfare : Competing Conceptions and Their Ethical Implications
The thesis of this book is that members of what I shall call the “animal welfare science community,”3 which includes both scientists and philosophers, have illegitimately appropriated the concept of animal welfare by claiming to have given a scientific account of it that is more objectively valid than the more sentimental” account given by animal liberationists.
Andean Archaeology III : North and South
In this volume, the strong cultural differences between northern and southern regions of the Central Andes are examined and the conditions under which these differences evolved are explored.
Anaphora and Type Logical Grammar
This book develops a hybrid architecture that allows to incorporate anaphora resolution into grammatical deduction while avoiding these consequences. To this end, the grammar logic is enriched with a connective that specifically deals with anaphora.After giving a self-contained introduction into Type Logical Grammar in general, the book discusses the formal properties of this connective. In the sequel, Jäger applies this machinery to numerous linguistic phenomena pertaining to the interaction of pronominal anaphora, VP ellipsis and quantification. In the final chapter, the framework is extended to indefiniteness, specificity and sluicing.
Analyzing uncertainty in civil engineering
This volume addresses the issue of uncertainty in civil engineering from design to construction. Failures do occur in practice. Attributing them to a residual system risk or a faulty execution of the project does not properly cover the range of causes. A closer scrutiny of the adopted design, the engineering model, the data, the soil-construction-interaction and the model assumptions is required. Usually, the uncertainties in initial and boundary conditions are abundant. Current engineering practice often leaves these issues aside, despite the fact that new scientific tools have been developed in the past decades that allow a rational description of uncertainties of all kinds, from model uncertainty to data uncertainty. It is the aim of this volume to have a critical look at current engineering risk concepts in order to raise awareness of uncertainty in numerical computations, shortcomings of a strictly probabilistic safety concept, geotechnical models of failure mechanisms and their implications for construction management, execution, and the juristic question of responsibility. In addition, a number of the new procedures for modelling uncertainty are explained.
Analytical Ultracentrifugation VIII
This book presents a comprehensive collection of 21 contributions from leading scientists in this field covering a broad spectrum of topics and presenting recent progress concerning instrumentation, data analysis and modeling, biological systems, particles, colloids, synthetic macromolecules, interacting systems. Due to the versatility of this fascinating and powerful technique, information and original publications are widespread and comprehensive collections are rare. Therefore, this volume presents a valuable source for biologists, chemists, materials scientists, and physicists interested in most recent information, results and development related to this important analytical method.
Analytical Ultracentrifugation of Polymers and Nanoparticles
Analytical ultracentrifugation (AUC) is a powerful method for the characterization of polymers, biopolymers, polyelectrolytes, nanoparticles, dispersions, and other colloidal systems. The method is able to determine the molar mass, the particle size, the particle density and interaction parameters like virial coefficients and association constants. Because AUC is also a fractionation method, the determination of the molar mass distribution, the particle size distribution, and the particle density distribution is possible. A special technique, the density gradient method, allows fractionating heterogeneous samples according to their chemical nature that means being able to detect chemical heterogeneity.
Analytical Methods for Problems of Molecular Transport
"This book is designed to serve a dual function. It is intended that it be capable of serving as a teaching instrument, either in a classroom environment or independently, for the study of basic analytical methods and mathematical techniques that may be used in the Kinetic Theory of Gases and is primarily suitable for use in graduate level physics and engineering courses on the subject. This book should also be useful as a reference for scientists and engineers working in the fields of Rarefied Gas Dynamics and Aerosol Mechanics. In addition, the material in this book may be of interest to individuals working in such areas as Physical Chemistry, Chemical Engineering, or any other applied discipline in which gas-surface interactions should play a significant role."-
Analytical Chemistry : Theoretical and Metrological Fundamentals
Fundamentals of Analytical Chemistry are usually presented as a sum of chemical and physical foundations, laws, axioms and equations for analytical methods and procedures. In contrast, this book delivers a practice-oriented, general guiding theory valid for all methods and techniques. Starting with a closer look to analytical signals and their dependencies, all the important figures of merit characterizing the power of analytical procedures and the reliability of analytical results are discussed and quantified, such as sensitivity, precision, accuracy and ruggedness. Elements of signal theory, information theory, statistics and fundamentals of calibration are also presented for this aim.
Analytical and Numerical Approaches to Mathematical Relativity
This book contains a representative collection of surveys by experts in mathematical relativity writing about the current status of, and problems in, their fields. There are four contributions for each of the following mathematical areas: differential geometry and differential topology, analytical methods and differential equations, and numerical methods. This book addresses graduate students and specialist researchers alike.
Analytical and Hybrid Methods in the Theory of Slot-Hole Coupling of Electrodynamic Vol.s
This book provides the reader with the possibility of rapid study and application of methods of computer analysis of electrodynamic problems. The authors address the development of analytical methods to solve the problems of diffraction of waveguide electromagnetic waves on slot coupling holes.
Analytic Methods for Design Practice
In the competitive world of modern engineering, rigorous and definite design methodologies are needed. However, many parts of engineering design are performed in either an ad-hoc manner or based on the intuition of the engineer.Analytic Methods for Design Practice is the first book to look at both stages of the design process – conceptual design and detailed design – and detail design methodologies for every step of the entire design process. The book introduces the following analytic design methodologies and explores their usefulness with many mathematical and practical examples: Axiomatic design; Optimization; Design of experiments; Robust design; Structural optimization; Dynamic response optimization; and Multidisciplinary optimization. A chapter of the book is devoted to case studies showing how practical design problems can be solved with analytic design methods based on Professor Park’s experiences of teaching design engineering over the past ten years.
Analysis, Synthesis, and Perception of Musical Sounds : The Sound of Music
Analysis, Synthesis, and Perception of Musical Sounds contains a detailed treatment of basic methods for analysis and synthesis of musical sounds, including the phase vocoder method, the McAulay-Quatieri frequency-tracking method, the constant-Q transform, and methods for pitch tracking with several examples shown. Various aspects of musical sound spectra such as spectral envelope, spectral centroid, spectral flux, and spectral irregularity are defined and discussed. One chapter is devoted to the control and synthesis of spectral envelopes. Two advanced methods of analysis/synthesis are given: "Sines Plus Transients Plus Noise" and "Spectrotemporal Reassignment" are covered. Methods for timbre morphing are given. The last two chapters discuss the perception of musical sounds based on discrimination and multidimensional scaling timbre models.
Analysis, Modeling and Simulation of Multiscale Problems
This book reports recent mathematical developments in the Programme "Analysis, Modeling and Simulation of Multiscale Problems", which started as a German research initiative in 2006. Multiscale problems occur in many fields of science, such as microstructures in materials, sharp-interface models, many-particle systems and motions on different spatial and temporal scales in quantum mechanics or in molecular dynamics. The book presents current mathematical foundations of modeling, and proposes efficient numerical treatment.
Analysis of variance for random models, Vol. 2 : Unbalanced data : Theory, methods, applications, and data analysis
Analysis of variance (ANOVA) models have become widely used tools and play a fundamental role in much of the application of statistics today. In particular, ANOVA models involving random effects have found widespread application to experimental design in a variety of fields requiring measurements of variance, including agriculture, biology, animal breeding, applied genetics, econometrics, quality control, medicine, engineering, and social sciences. This two-volume work is a comprehensive presentation of different methods and techniques for point estimation, interval estimation, and tests of hypotheses for linear models involving random effects. Both Bayesian and repeated sampling procedures are considered. Volume I examines models with balanced data (orthogonal models); Volume II studies models with unbalanced data (nonorthogonal models).
Analysis of seawater : A guide for the analytical and environmental chemist
It is only in the past few years that methods of adequate sensitivity have become available for true ultra-trace metal determinations in water. In the case of organics in seawater it has now become possible to resolve the complex mixtures of organics in seawater and achieve the required very low detection limits. Fortunately, the interest in micro-constituents in the seawater both from the environmental and the nutrient balance points of view has coincided with the availability of advanced instrumentation capable of meeting the analytical needs. This complete and up-to-date compilation of the currently employed proven methods for the chemical analysis of seawaters includes 45 tables and 48 figures.
