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Advanced Peripheral Nerve Surgery and Minimal Invasive Spinal Surgery

A summary of the most recent and effective techniques for treating difficult functional problems and painful situations using minimally invasive spinal surgery techniques. Including an up-to-date review of the physiopathology of the diseases.

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Adrenomedullin in Cardiovascular Disease

Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.

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Adrenal Glands : Diagnostic Aspects and Surgical Therapy

Surgery of the Adrenal Glands is a comprehensive medical textbook that includes everything that a surgeon, but for all purposes any physicain or medical student, may want to find on adrenal surgery in a friendly, up to date, evidence based manner. 30 of the most renowned names in the field of adrenal surgery from the US and Europe draw on their experience in exploring diagnosis, indications for surgery, choice of operation and operative techniques, and surgical outcomes for every major adrenal condition. Over 200 exquisite illustrations, ranging from intraoperative photographs, line drawings, diagnostic images, pathology slides, tables and graphs are available to make each case discussed comprehensible and easy to follow. Traditional and novel therapeutic recommendations are introduced and the latest developments in minimal-access operative techniques are discussed and reviewed. Finally, the best approaches in dealing with challenging conditions such as adrenal incidentaloma, subclinical Cushing's syndrom, Congenital Adrenal Hyperplasia, Mineralcorticoid Express Syndrome, Extraadrenal and Malignant Pheochromocytoma are discussed.

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Adipose Tissue and Adipokines in Health and Disease

The aim of Adipose Tissue and Adipokines in Health and Disease is to provide comprehensive information regarding adipose tissue, its physiological functions and its role in disease. This volume contains a collection of information spanning the entire range of adipose tissue studies, from basic anatomical and physiological research to epidemiology and clinical aspects, in one place. This book is indispensable for basic researchers and clinicians interested in the fields of obesity, metabolic diseases, inflammation and immunity, and specialists in each of the pathologies associated with obesity.

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Acute Myelogenous Leukemia

The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. Bringing together new concepts and findings in the basic and clinical science of AML, the book emphasizes the molecular basis for new therapies that stand to have the greatest potential impact on the clinical face of these diseases. The text provides insights into selected novel strategies currently and prospectively being developed, including interruption of specific signal transduction pathways, modulation of gene expression, attempts to reinstate differentiation, and immunomodulation.

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Acute Heart Failure

Acute Heart Failure informs cardiology, intensive care, and emergency medicine physicians on the diagnosis and management of severe acute heart failure from epidemiology through to diagnosis and treatment.

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Acute coronary syndrome : Multidisciplinary and pathway-based approach

Acute coronary syndrome (ACS) affects millions of patients annually and requires immediate diagnosis and therapy. This practical algorithm-based handbook addresses the diagnosis and treatment of these patients and is designed for the medical personnel involved in the triage and management of ACS patients.

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Actualités en rééducation des maladies neuro-musculaires de ladulte = News in rehabilitation of neuro-muscular diseases in adults

Neuro-muscular diseases include congenital or acquired pathologies of the muscle and the peripheral nerve. This book covers all the care of the adult patient with such a condition.

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Actin-Binding Proteins and Disease

This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin ¾4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.

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Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma : Complication of Long-Term Dialysis

I have been involved in the treatment of chronic renal insuf? new and unexpected pathological conditions have also appeared as complications of long-term dialysis. One of these involves polycystic changes and their malignant transformation in diseased kidneys. Since I have studied these polycystic changes and their malignant transformation for many years, I decided to compile the results of my work in a book. Such conditions of diseased kidneys pose serious problems, particularly in Japan, where renal transplantation is performed very infrequently compared with other countries, and a large number of patients are managed by dialysis over a long period.

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Abord clinique des urgences traumatiques au cabinet du généraliste = Clinical approach to traumatic emergencies in the general practitioner's office

Cet ouvrage a été conçu comme une aide pour le médecin généraliste, confronté quotidiennement à la pathologie traumatique. Les deux auteurs, urgentistes expérimentés, apportent des réponses claires, concises et pratiques aux problèmes que posent les lésions traumatiques. Des gestes simples, un abord clinique détaillé, la nécessité de recourir ou non à des examens complémentaires ou à un avis spécialisé sont ici expliqués et justifiés. Le style est précis, concis, et un lexique complète les définitions et les matériels cités dans le texte. Les auteurs se sont entourés des avis de généralistes et de spécialistes pour définir des conduites à tenir simples et compatibles avec les nécessités du terrain.

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Abord clinique des malades de lalcool : En médecine générale = Clinical approach to patients with alcoholism : In general medicine

Les médecins généralistes sont destinataires d’un grand nombre d’informations sur l’alcool, son usage et ses conséquences pathologiques immédiates ou potentielles. Ces connaissances, émanant de médecins le plus souvent hospitaliers et spécialisés, ont conduit à des recommandations destinées à guider les médecins généralistes dans le repérage des malades de l’alcool et leur prise en charge thérapeutique. Cependant, la pertinence et l’applicabilité de la plupart de ces recommandations sont peu ou mal évaluées dans la pratique de la médecine générale. De ce fait, les médecins généralistes, parfois à l’encontre des recommandations, sont amenés à élaborer des concepts et des pratiques propres à leur clientèle et à leurs conditions de travail. L’originalité de ce livre vient de la confrontation des connaissances et des pratiques de deux médecins, soignant des malades de l’alcool dans des structures différentes.

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Abeta Peptide and Alzheimers Disease : Celebrating a Century of Research

Abeta Peptide and Alzheimer’s Disease summarizes current knowledge of beta-amyloid peptide (Aß) and its role as the major culprit in Alzheimer’s Disease (AD), shown by recent advances in genetics and brain biochemistry.the book covers fundamental biochemical studies on the Aß peptide, the genetic impact on Aß expression and processing, and various AD therapeutic strategies that target Aß. Although specifically focusing on Aß and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases.

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A Time for Metabolism and Hormones

Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

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A History of Radionuclide Studies in the UK : 50th Anniversary of the British Nuclear Medicine Society

The British Nuclear Medicine Society celebrates its 50th Anniversary with this booklet, which reflects the research of many of the pioneers in the use of radionuclides for the diagnosis and therapy of human disease. Since 1949 there have been remarkable advances in radionuclide techniques and imaging equipment: from the first devices “home-made” in the many physics departments throughout the UK, to the sophisticated multimodality imagers now in everyday use in Nuclear Medicine. The BNMS has been instrumental in promoting the use of radionuclide techniques in the investigation of pathology by supporting and providing education, research and guidelines on the optimum use of radiation to help patients.

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25 Years of P53 Research

Communication, awareness and access to information: Given the complexity of the field and the fact that data pertaining to each particular aspects of p53 biology or deregulation are scattered in many different publications, it is extremely difficult to access the full scale of relevant information of any specific p53-related topic. This book may help in this task by putting into perspective both general considerations on the p53 pathway and more specific information on various aspects of p53. In the longer term, however, open access to p53 complexity will require the development of knowledge bases accessible through the web and using simple navigation tools to guide users towards the specific information they need. Several efforts are currently being developed in that direction. They need to be strenghtened and better integrated within the rapidly growing galaxy of web-based information sources on molecular and individual variations in cancer. 2. Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard, universally accepted assays to measure critical p53 protein functions.

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Beginning XSLT 2.0 : From novice to professional

This followup to Jeni Tennison's Beginning XSLT has been updated to accomodate the revised XSLT standard. Part one of this book introduces XML and XSLT at a comfortable pace, and gradually demonstrates techniques for generating HTML (plus other formats), from XML. In part two, Tennison applies theory to real-life XSLT capabilities—including generating graphics. Each chapter includes step-by-step examples (with code available online), plus review questions at the end, to help you grasp the discussed features. In fact, all of the examples and exercises revolve around an interesting common theme: making TV listings available online. This book lives up to its name, and will definitely take you from a novice to a professional, in no time!

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Beginning xml with C# 2008 : From novice to professional

Beginning XML with C# 2008 focuses on XML and how it is used within .NET 3.5. As you'd expect of a modern application framework, .NET 3.5 has extensive support for XML in everything from data access to configuration, from raw parsing to code documentation. This book demystifies all of this. It explains the basics of XML as well as the namespaces and objects you need to know in order to work efficiently with XML. You will see clear, practical examples that illustrate best practices in action. With this book, you'll learn everything you need to know from the basics of reading and writing XML data to using the DOM, from LINQ and SQL Server integration to SOAP and web services.

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Beginning GIMP : From novice to professional

Beginning GIMP: From Novice to Professional explains how to use the open source image manipulation program, GIMP version 2.4. You'll learn how to install GIMP on Windows, Linux, and MacOS X platforms. Once you've installed the application, you'll learn about the interface and configuration options, and then jump into a quick–and–simple project to familiarize yourself even further. With four–color graphics and screenshots throughout, you'll learn how to prepare camera images for display on web pagesincluding functions like rescaling, cropping, and balancing color. The book also explains with great detail how to utilize layers, paths, and masks. You'll also learn how to draw lines and shapes, use patterns and gradients, and even create your own brushes, patterns, and gradients.

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Bayesian Methods in the Search for MH370

This book demonstrates how nonlinear/non-Gaussian Bayesian time series estimation methods were used to produce a probability distribution of potential MH370 flight paths. It provides details of how the probabilistic models of aircraft flight dynamics, satellite communication system measurements, environmental effects and radar data were constructed and calibrated. The probability distribution was used to define the search zone in the southern Indian Ocean. The book describes particle-filter based numerical calculation of the aircraft flight-path probability distribution and validates the method using data from several of the involved aircraft’s previous flights. Finally it is shown how the Reunion Island flaperon debris find affects the search probability distribution.

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