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Mammalian and Avian Transgenesis : New Approaches

Mammalian and Avian Transgenesis presents a collection of novel methods for the production of a wide range of transgenic animals. The manual focuses largely on mice, but also contains protocols for successful transgenesis in rats, cows, pigs and birds. The manual provides detailed, step-by-step protocols covering all aspects of the production of transgenic animals, including the use of lentiviral vectors in gene transfer, intracytoplasmic sperm injection, nuclear transfer, large insert transgenesis, conditional gene expression systems, the use of reporter genes in transgenesis and transgenesis in large animals and birds. The text is supplemented by superb color photos. While the focus is on newly established techniques, the fundamental methods of transgenesis are also covered for those new to the field. Thus this manual is perfectly suited for those wishing to adopt new technologies in transgenesis.

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Cardiac gene therapy : Methods and protocols

Discussions on topics such as gene suppression, editing, and reprogramming; cardiac gene therapy vectors and promoters; cardiac gene delivery methods; pulmonary hypertension; and patient screening and measuring the efficacy of cardiac gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Bridging laboratory and field research for genetic control of disease vectors

Contemporary research on genetic control of disease-transmitting insects knows two kinds of scientists: those that work in the laboratory and those known as ‘field people’. Over the last decade, both groups seem to have developed differing research priorities, address fundamentally different aspects within the overall discipline of infectious-disease control, and worse, have developed a scientific ‘language’ that is no longer understood by the ‘other’ party. This gap widens every day, between the North and the South, between ecologists and molecular biologists, geneticists and behaviourists, etc. The need to develop a common research agenda that bridges this gap has been identified as a top priority by all parties involved. Only then shall the goal of developing appropriate genetic-control strategies for vectors of disease become reality.

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Baculovirus : Methods and protocols

Provides up-to-date guidance on techniques used to work with baculoviruses and insect cells. The book provides basic methods to create recombinant baculoviruses, to improve productivity, to produce a variety of products, to purify products, to quantify baculovirus stocks or to quantify product produced, and it concludes with alternative uses of either baculovirus or insect cells as tools. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Bacterial Biofilms

This volume tends to focus on the biology of biofilms that affect human disease. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth. The next chapters are devoted to common problematic biofilms, those that colonize venous and urinary catheters. The final series of chapters examines biofilm formation by four species that are important pathogens and well studied models, one of which, Yersinia pestis, cleverly adopts a biofilm state of growth within its insect vector to promote disease transmission to mammalian hosts.

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Autoformation et aide au diagnostic en hématologie avec le logiciel ADH = Self-study and diagnostic aid in hematology with ADH software

The software includes a rich iconography on blood and marrow cells which will complement the knowledge in cytology of hematologists. Certain cytological abnormalities encountered in certain pathologies are also presented.

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An ecological and societal approach to biological control

Biological control is among the most promising methods for control of pests (including vectors), diseases and weeds. In this book ecological and societal aspects are for the first time treated together. In an ecological approach the aim is to evaluate the significance of certain biological properties like biodiversity and natural habitats. Also, it is important to see biological control from an organic (or ecological) farming point of view. In a societal approach terms like ‘consumer’s attitude’, ‘risk perception’, ‘learning and education’ and ‘value triangle’ are recognised as significant for biological production and human welfare.

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Abord clinique des urgences traumatiques au cabinet du généraliste = Clinical approach to traumatic emergencies in the general practitioner's office

Cet ouvrage a été conçu comme une aide pour le médecin généraliste, confronté quotidiennement à la pathologie traumatique. Les deux auteurs, urgentistes expérimentés, apportent des réponses claires, concises et pratiques aux problèmes que posent les lésions traumatiques. Des gestes simples, un abord clinique détaillé, la nécessité de recourir ou non à des examens complémentaires ou à un avis spécialisé sont ici expliqués et justifiés. Le style est précis, concis, et un lexique complète les définitions et les matériels cités dans le texte. Les auteurs se sont entourés des avis de généralistes et de spécialistes pour définir des conduites à tenir simples et compatibles avec les nécessités du terrain.

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Comparative and international criminal justice systems : policing, judiciary, and corrections

The Nature of Comparative and International Criminal JusticeThe Purpose of Comparative and International Criminal Justice Systems; Crime and Criminal Law: Global PerspectiveCrime: International and Comparative;Overview of Model Criminal Justice Systems

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Machine-learning-assisted intelligent processing and optimization of complex systems

Focuses on the most recent developments in intelligent optimization methods and their applications in various test cases. The reprint covers various topics, including distributed multiagent modeling, metaheuristic algorithms, multisource data fusion, mobile computing and mobile sensing, machine learning-based intelligent processing for modeling complex manufacturing systems, and data-driven intelligent modeling

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Machine Learning for Multimedia Content Analysis

Challenges in complexity and variability of multimedia data have led to revolutions in machine learning techniques. Multimedia data, such as digital images, audio streams and motion video programs, exhibit richer structures than simple, isolated data items. A number of pixels in a digital image collectively conveys certain visual content to viewers. A TV video program consists of both audio and image streams that unfold the underlying story.  To recognize the visual content of a digital image, or to understand the underlying story of a video program, we may need to label sets of pixels or groups of image and audio frames jointly.

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Java 17 Recipes : A Problem-Solution Approach

Quickly find solutions to dozens of common programming problems encountered while building Java applications, with recipes presented in the popular problem-solution format. Look up the programming problem that you want to resolve. Read the solution. Apply the solution directly in your own code. Problem solved! covers of some of the newest features, APIs, and more such as pattern matching for switch, Restore Always-Strict-Floating-Point-Semantics, enhanced pseudo-random number generators, the vector API, sealed classes, and enhancements in the use of String. Source code for all recipes is available in a dedicated GitHub repository. This must-have reference belongs in your library. You will learn : Look up solutions to everyday problems involving Java SE 17 LTS and other recent releases / Develop Java SE applications using the latest in Java SE technology / Incorporate Java major features introduced in versions 17, 16, and 15 into your code

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Beginning XSLT 2.0 : From novice to professional

This followup to Jeni Tennison's Beginning XSLT has been updated to accomodate the revised XSLT standard. Part one of this book introduces XML and XSLT at a comfortable pace, and gradually demonstrates techniques for generating HTML (plus other formats), from XML. In part two, Tennison applies theory to real-life XSLT capabilities—including generating graphics. Each chapter includes step-by-step examples (with code available online), plus review questions at the end, to help you grasp the discussed features. In fact, all of the examples and exercises revolve around an interesting common theme: making TV listings available online. This book lives up to its name, and will definitely take you from a novice to a professional, in no time!

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Artificial intelligence techniques in hydrology and water resources management

The sustainable management of water cycles is crucial in the context of climate change and global warming. It involves managing global, regional, and local water cycles, as well as urban, agricultural, and industrial water cycles, to conserve water resources and their relationships with energy, food, microclimates, biodiversity, ecosystem functioning, and anthropogenic activities. Hydrological modeling is indispensable for achieving this goal, as it is essential for water resources management and the mitigation of natural disasters. In recent decades, the application of artificial intelligence (AI) techniques in hydrology and water resources management has led to notable advances. In the face of hydro-geo-meteorological uncertainty, AI approaches have proven to be powerful tools for accurately modeling complex, nonlinear hydrological processes and effectively utilizing various digital and imaging data sources, such as ground gauges, remote sensing tools, and in situ Internet of Things (IoT) devices.

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Algorithmic learning theory ; Vol. 3734 ; 16th international conference, ALT 2005, Singapore, October 8-11, 2005, Proceedings

This volume contains the papers presented at the 16th Annual InternationalConference on Algorithmic Learning Theory (ALT 2005), which was held (Republic of Singapore), 2005. The main objective of theconference is to provide an interdisciplinary forum for the discussion of the the-oretical foundations of machine learning as well as their relevance to practicalapplications. The volume includes 30 technical contributions, which were selected by theprogram committee from 98 submissions.

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Algorithmic learning theory ; 18th International conference, ALT 2007, Sendai, Japan, October 1-4, 2007, Proceedings

This volume contains the papers presented at the 18th International Conf- ence on Algorithmic Learning Theory.The main objective of the conference was to provide an interdisciplinary forum for high-quality talks with a strong theore- cal background and scientiبهc interchange in areas such as query models, on-line learning, inductive inference, algorithmic forecasting, boosting, support vector machines, kernel methods, complexity and learning, reinforcement learning, - supervised learning and grammatical inference.

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Algorithmic Learning in a Random World

This new monograph integrates mathematical theory and revealing experimental work. It demonstrates mathematically the validity of the reliability claimed by conformal predictors when they are applied to independent and identically distributed data, and it confirms experimentally that the accuracy is sufficient for many practical problems. Later chapters generalize these results to models called repetitive structures, which originate in the algorithmic theory of randomness and statistical physics. The approach is flexible enough to incorporate most existing methods of machine learning, including newer methods such as boosting and support vector machines and older methods such as nearest neighbors and the bootstrap.

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Advances in optical fiber communications

Given the increasing importance of a globally interconnected world, driven by modern digital services and the need for fast and reliable access to digital resources, communication networks are one of the key infrastructures in today’s society. In this scenario, fiber optics and optical devices play a leading role, as they allow for unprecedented growth in our capacity to cope with the ever-increasing traffic demand. Optical transmission solutions range from high-speed networks based on coherent detection and advanced modulation formats for long-haul-level communications, to networks still relying on traditional intensity modulation and direct detection receivers for short-reach communications, down to intra-data center scenarios.

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Advances in Big Data Analytics : Theory, Algorithms and Practices

Provides a comprehensive and cutting-edge study on big data analytics, based on the research findings and applications developed by the author and his colleagues in related areas. It addresses the concepts of big data analytics and/or data science, multi-criteria optimization for learning, expert and rule-based data analysis, support vector machines for classification, feature selection, data stream analysis, learning analysis, sentiment analysis, link analysis, and evaluation analysis. The book also explores lessons learned in applying big data to business, engineering and healthcare. Lastly, it addresses the advanced topic of intelligence-quotient (IQ) tests for artificial intelligence.

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AdvancED Flash Interface Design

Flash allows users to create some amazing interactive interfaces to interact with rich Internet applications, e-learning systems, and simple web sites. In this book, two of the most talented Flash designers in the world will show you how to use them effectively to create breathtaking visuals for your Flash web sites. You'll also learn how to take advantage of Flash's powerful built-in vector-based drawing tools.

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