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A History of Physical Theories of Comets, From Aristotle to Whipple
The book describes the major physical theories of comets in the past two millennia. It demonstrates the evolution of ideas about the nature, position, motion and physical constitution of comets from Aristotle to Whipple. Unlike the available works on the history of comets, which either illustrate relatively short periods in the history of physical cometology or portray a landscape view without adequate details, the present study focuses on details of each theory. It also investigates the interaction between observational and mathematical astronomy, and the physical sciences in defining the properties of comets.
Mass Vaccination : Global Aspects - Progress and Obstacles
Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.
Marijuana and the Cannabinoids
Although primarily used today as one of the most prevalent illicit leisure drugs, the use of Cannabis sativa L., commonly referred to as marijuana, for medicinal purposes has been reported for more than 5000 years. Marijuana use has been shown to create numerous health problems, and, consequently, the expanding use beyond medical purposes into recreational use (abuse) resulted in control of the drug through international treaties. Much research has been carried out over the past few decades following the identification of the chemical structure of THC.The purpose of Marijuana and the Cannabinoids is to present in a single volume the comprehensive knowledge and experience of renowned researchers and scientists. Each chapter is written independently by an expert in his/her field of endeavor, ranging from the botany, the constituents, the chemistry and pharmacokinetics, the effects and consequences of illicit use on the human body, to the therapeutic potential of the cannabinoids.
Manual of cardiovascular medicine
Cardiovascular medicine has experienced an unforeseen and impressive development over the last fifty years, particularly recently, as new diagnostic innovative medications have been developed, as well as interventional and surgical procedures to treat patients with cardiac disease. Thus, the number of cardiovascular diagnoses, the number of diagnostic modalities, as well as the number of treatment options has expanded enormously and made cardiovascular medicine one of the biggest specialties in medicine. This cardiovascular manual focuses on diagnostic algorithms and therapeutic recommendations according to European Guidelines. It encompasses all aspects of cardiovascular medicine from hypertension to transplantation; from imaging to intervention; and from pharmacotherapy to surgical procedures.
Malignant Mesothelioma : Pathogenesis, Diagnosis, and Translational Therapies
(Review from JAMA) Malignant mesothelioma is an uncommon neoplasm usually associated with exposure to asbestos. Because of its low incidence, thorough reviews of the topic are hard to find. Harvey Pass and colleagues have edited an up-to-date, comprehensive book that includes a wide range of information, from a historical perspective to descriptions of the latest treatment. The authors . . . have written chapters on the carcinogenesis, molecular genetics, and clinical aspects of mesothelioma. Malignant Mesothelioma is suitable for a broad audience. Laboratory researchers will use it as a resource for information about the pathogenesis, animal models, molecular genetics, and cell lines of mesothelioma. . . . Clinicians will benefit from this complete guide to the presentation, prognosis, imaging, and treatment of the disease. I highly recommend this book to all who are interested in mesothelioma.
Lymphocyte Signal Transduction
Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational modifications, lead to the activation of transcription factors that mediate cellular differentiation and growth, effector cell functions, and apoptotic cell death. Several investigators from various parts of the world convened at the 3rd Lymphocyte Signal Transduction Workshop in Crete, Greece from May 27 to June 1, 2005 to discuss their most recent findings in leukocyte signaling. This volume represents a collection of topics discussed during the conference.
Listeria Monocytogenes : Pathogenesis and Host Response
This comprehensive volume, written by experts in the field, includes concise and timely reviews of Listeria monocytogenes, one of the most intensively studied bacterial pathogens. Listeria monocytogenes is the cause of listeriosis, a potentially fatal disease that arises from the consumption of contaminated food. During the past two decades, studies of this organism have uncovered a wealth of information on its virulence factors, its genome organization, and its interactions with host cells and the immune system.
Linsuffisance cardiaque aiguë = Acute heart failure
Acute heart failure is one of the oldest described medical conditions. However, although its clinical symptomatology is fairly obvious and known to everyone: dyspnea, liver pain, crackles on auscultation, the epidemiology has only been explored for very recent years. In all of the cardiology and resuscitation books of the past 40 years, acute heart failure has been considered a catch-all ranging from acute simple lung edema in hypertensive crisis to cardiogenic shock following heart attack. myocardium. It was all called "acute heart failure." This book is based on the recent Recommendations of the European Society of Cardiology and the European Society of Intensive Care Medicine which advocate the designation "Acute heart failure syndrome" in which the decompensation of heart failure chronic, hypertensive surge, cardiogenic shock, right heart failure, and high output heart failure are separate entities.
Lemurs : Ecology and Adaptation
In this comprehensive volume, written by experts in the field, information gathered on lemur ecology and adaptation over the past 15 years is presented by both seasoned and newer lemur researchers, and provides us with further knowledge concerning both well-studied and rarely studied extant species, as well as insights into the ecology and adaptation of some of the recently extinct lemurs.
Lassativi : Impiego razionale dei lassativi nella stipsi = assatives : Rational use of laxatives in constipation
An extensive compendium on laxatives. It covers all aspects of the clinical use of laxatives complete with physiological information related to constipation. The mechanisms of action of the main classes of laxatives are widely described. The text contains illustrations that help to understand the origins of plant laxatives and the pharmacology of the most interesting ones. Doctors, pharmacists, herbalists, nurses and students will find this volume interesting and useful.
Landscapes, Genomics and Transgenic Conifers
What is the future of genetically modified (or transgenic) conifer plantations? The content of this edited volume Landscapes, Genomics and Transgenic Conifers addresses this question directly - and indirectly - using language drawn from policy, forest history, genomics, metabolism, pollen dispersal and gene flow, landscape ecology, evolution, economics, technology transfer and regulatory oversight. Although the book takes its title from a Nicholas School Leadership forum held November 17-19, 2004 at Duke University, its de novo contents move past the forum’s deliberations. The result is a trans-disciplinary book composed of 14 chapters written by a total of 31 authors working in North America, South America, Europe and Africa.
La réanimation neurochirurgicale = Neurosurgical resuscitation
«decade of the brain », s’est ajouté en clinique humaine le développement des nouvelles techniques d’imagerie. Ceci a permis d'enterrer enfin certaines idées anciennes et de développer de nouvelles stratégies thérapeutiques fondées sur une meilleure compréhension des mécanismes physiopathologiques de l’agression cérébrale en transposant les résultats de la recherche fondamentale dans la pratique de tous les jours. Il ne fait aucun doute que le médecin, qu'il soit anesthésiste, réanimateur, urgentiste, qui serait passé « à côté » de cette période concernant la prise en charge globale du cerveau agressé se retrouverait distancé face à la prise en charge actuelle et n’aurait pas en main les moyens d’en comprendre sa justification. L’association de neuro-anesthésie réanimation de langue Française
La marche de linfirme moteur cérébral enfant et adulte = Gait in children and adults with cerebral palsy
Patients with cerebral palsy (CP) face numerous neuromotor problems related to brain damage, the functional consequences of which, in the early years of life, impact the acquisition of walking. A better understanding of gait and its levels of control, along with refined and quantified clinical analysis in the laboratory, allows for the definition of therapeutic options in collaboration with the patient, their family, and the healthcare team. Managing muscle tone disorders and neuro-orthopedic problems is a daily challenge for patients at all ages. Patients with CP increasingly benefit from new drug therapies, regular adjustments of walking aids and orthotics, and specific rehabilitation, sometimes combined with surgical procedures, whether orthopedic or neurological. This book reviews the evolution of knowledge and practices.
La fitoterapia in uno sguardo = Phytotherapy at a glance
This volume summarizes notions of phytotherapy; the intent is to offer the doctor essential knowledge so that he can easily prescribe plant products and to stimulate the pharmacist and herbalist to use them in a more rational way.
La colonscopia virtuale = The virtual colonoscopy
The text intends to provide the radiologist, specialized in the study of the colon, with a complete update on this innovative technique which, as confirmed by the very recent Guidelines published by the American Cancer Society and the American Gastroenterological Association.
KRAS : Methods and protocols
Details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models.
Complex Intracellular Structures in Prokaryotes
The new series "Microbiology Monographs" begins with two volumes on intracellular components in prokaryotes. In this second volume, "Complex Intracellular Structures in Prokaryotes", the components, labeled complex intracellular structures, encompass a multitude of important cellular functions. Continuing and newly initiated research will provide a clearer understanding of the complex intracellular structures known at present and will bring to light surprising new ones as well.
Classic Papers in Coronary Angioplasty
Every medical specialty has a core of classic papers that reflect both the historical development of the discipline and point the way to present and future developments. The Editors of Classic Papers in Coronary Angioplasty have assembled a distinguished team of international contributors, to identify, analyze and bring together in a single volume the most important articles from a broad range of publications that have become recognized as the defining articles in coronary angioplasty.
Chromatin and Disease
It is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription, DNA repair, recombination and also apoptosis. The dynamic nature of the chromatin is regulated by chromatin modifications (epigenetic alterations), remodeling, histone chaperones and functional interactions of different chromatin interacting n- histone proteins. Dysfunction of this highly inter connected machineries disturb the cellular homoeostasis, and thereby causes several diseases. As we advance in our knowledge of chromatin function and also disease mechanisms in more details, their causal relationship is becoming more evident. This has lead to the identification of chromatin function as target for new generation therapeutics.
Chlorophylls and Bacteriochlorophylls : Biochemistry, Biophysics, Functions and Applications
This book summarizes the chemical, physical, biological and medical aspects of chlorophyll (and bacteriochlorophyll) research and development, with a focus on the tremendous progress achieved over the past 15 years. Each section has an up-to-date introductory overview which is followed by a series of concise well-focused and fully-referenced chapters written by experts in (bio)chemistry, (bio)physics, photobiology and photomedicine.
