Bioactive Confirmation II
Specific binding of a ligand to a receptor is a key step in a variety of biol- ical processes, such as immune reactions, enzyme cascades, or intracellular transport processes. The ligand-receptor terminology implies that the rec- tor molecule is signi?cantly larger than the ligand, and the term "bioactive conformation" usually characterizes the conformation of a ligand when it is bound to a receptor. In a more general sense, bioactive conformation applies toanymoleculeinabiologicallyrelevantboundstateregardlessofsizecons- erations. Mostofthecontributions tothisbookaddressligandsthat aremuch smaller than their receptors. X-ray crystallography and high resolution NMR spectroscopy are the two main experimental techniques used to study bioactive conformations. The- fore, the twovolumes ofthisbookcover approachesthat use either ofthetwo techniques, or a combination thereof.
Big Data Recommender Systems ; Vol.2 : Application Paradigms
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools. First designed to generate personalized recommendations to users in the 90s, recommender systems apply knowledge discovery techniques to users’ data to suggest information, products, and services that best match their preferences. In recent decades, we have seen an exponential increase in the volumes of data, which has introduced many new challenges. recommender systems. Volume 2 covers a broad range of application paradigms for recommender systems over 22 chapters
Big Data Recommender Systems ; Vol.1 : Algorithms, Architectures, Big Data, Security and Trust
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools.
Big Data Intelligence for Smart Applications
Presents the latest discoveries in the field of machine intelligence and big data Proposes many case studies and applications of computational and Big data Combines theory and practice so that readers of the few books (beginners or experts)
Big Data in Context : Legal, Social and Technological Insights
Sheds new light on a selection of big data scenarios from an interdisciplinary perspective. It features legal, sociological and economic approaches to fundamental big data topics such as privacy, data quality and the ECJ’s Safe Harbor decision on the one hand, and practical applications such as smart cars, wearables and web tracking on the other. Addressing the interests of researchers and practitioners alike, it provides a comprehensive overview of and introduction to the emerging challenges regarding big data.All contributions are based on papers submitted in connection with ABIDA (Assessing Big Data), an interdisciplinary research project exploring the societal aspects of big data and funded by the German Federal Ministry of Education and Research.
Big Data : An Art of Decision Making
Manipulating and processing masses of digital data is never a purely technical activity. It requires an interpretative and exploratory outlook - already well known in the social sciences and the humanities - to convey intelligible results from data analysis algorithms and create new knowledge. Big Data is based on an inquiry of several years within Proxem, a software publisher specializing in big data processing. The book examines how data scientists explore, interpret and visualize our digital traces to make sense of them, and to produce new knowledge. Grounded in epistemology and science and technology studies, Big Data offers a reflection on data in general, and on how they help us to better understand reality and decide on our daily actions.
Bifurcations, Instabilities, Degradation in Geomechanics
Leading international researchers and practitioners of bifurcations and instabilities in geomechanics debate the developments and applications which have occurred over the last few decades. The topics covered include modeling of bifurcation, structural failure of geomaterials and geostructures, advanced analytical, numerical and experimental techniques, and application and development of generalised continuum models etc. In addition analytical solutions, numerical methods, experimental techniques, and case histories are presented. Beside fundamental research findings, applications in geotechnical, petroleum, mining, and bulk materials engineering are emphasised.
Bidding Strategies in Agent-Based Continuous Double Auctions
Presents a new bidding strategy for agents to adopt in CDAs and propose tools to enhance the performance of existing bidding strategies in CDAs. The superior performance of the new bidding strategy as well as the tools presented in this book are illustrated through extensive experiments.
Beyond the apparent Banality of the mathematics classroom
New research in mathematics education deals with the complexity of the mathematics’ classroom. The classroom teaching situation constitutes a pertinent unit of analysis for research into the ternary didactic relationship which binds teachers, students and mathematical knowledge. The classroom is considered as a complex didactic system, which offers the researcher an opportunity to gauge the boundaries of the freedom that is left with regard to choices about the knowledge to be taught and the ways of organizing the students’ learning, while giveing rise to the study of interrelations between three main elements of the teaching process the: mathematical content to be taught and learned, management of the various time dimensions, and activity of the teacher who prepares and manages the class, to the benefit of the students' knowledge and the teachers' own experience.
Beyond Cartesian Dualism : Encountering affect in the teaching and learning of science.
There is surprisingly little known about affect in science education. Despite periodic forays into monitoring students’ attitudes-toward-science, the effect of affect is too often overlooked. Beyond Cartesian Dualism gathers together contemporary theorizing in this axiomatic area. In fourteen chapters, senior scholars of international standing use their knowledge of the literature and empirical data to model the relationship between cognition and affect in science education. Their revealing discussions are grounded in a broad range of educational contexts including school classrooms, universities, science centres, travelling exhibits and refugee camps, and explore an array of far reaching questions. What is known about science teachers’ and students’ emotions? How do emotions mediate and moderate instruction? How might science education promote psychological
Best practices in software measurement : How to use metrics to improve project and process performance
Not everything that counts can be counted. Not everything that is counted counts. Albert Einstein This is a book about software measurement from the practitioner’s point of view and it is a book for practitioners. Software measurement needs a lot of practical guidance to build upon experiences and to avoid repeating errors. This book t- gets exactly this need, namely to share experiences in a constructive way that can be followed. It tries to summarize experiences and knowledge about software measurement so that it is applicable and repeatable. It extracts experiences and lessons learned from the narrow context of the specific industrial situation, thus facilitating transfer to other contexts. Software measurement is not at a standstill. With the speed software engine- ing is evolving, software measurement has to keep pace. While the underlying theory and basic principles remain invariant in the true sense (after all, they are not specific to software engineering), the application of measurement to specific contexts and situations is continuously extended. The book thus serves as a ref- ence on these invariant principles as well as a practical guidance on how to make software measurement a success.
Bernoulli potential in superconductors : How the electrostatic field helps to understand superconductivity
The motion of electrons in superconductors seems to defy our imagination based on daily experience with Newtonian mechanics. This book shows that the classical concepts, such as the balance of forces acting on electrons, are useful for understanding superconductivity. The electrostatic field plays a natural part in this balance as it mediates forces between electrons at long distances. Due to its classical interpretation, the theory presented in this book is suitable for introductory courses.
Beginning XSLT 2.0 : From novice to professional
This followup to Jeni Tennison's Beginning XSLT has been updated to accomodate the revised XSLT standard. Part one of this book introduces XML and XSLT at a comfortable pace, and gradually demonstrates techniques for generating HTML (plus other formats), from XML. In part two, Tennison applies theory to real-life XSLT capabilities—including generating graphics. Each chapter includes step-by-step examples (with code available online), plus review questions at the end, to help you grasp the discussed features. In fact, all of the examples and exercises revolve around an interesting common theme: making TV listings available online. This book lives up to its name, and will definitely take you from a novice to a professional, in no time!
Beginning xml with C# 2008 : From novice to professional
Beginning XML with C# 2008 focuses on XML and how it is used within .NET 3.5. As you'd expect of a modern application framework, .NET 3.5 has extensive support for XML in everything from data access to configuration, from raw parsing to code documentation. This book demystifies all of this. It explains the basics of XML as well as the namespaces and objects you need to know in order to work efficiently with XML. You will see clear, practical examples that illustrate best practices in action. With this book, you'll learn everything you need to know from the basics of reading and writing XML data to using the DOM, from LINQ and SQL Server integration to SOAP and web services.
Beginning Web Development, Silverlight, and ASP.NET AJAX : From novice to professional
Beginning Web Development, Silverlight, and ASP.NET AJAX: From Novice to Professional aims to give you the skills you need to start building web applications with Microsoft's next–generation technology as quickly as possible. Whether you're interested in ASP.NET AJAX, Silverlight, or the technologies that support them (WPF, WCF, WF, etc.), this book is the starting point that you need. It adopts a “zero to hero” approach that concentrates on achieving practical results you can use in real projects rather than presenting a deep academic treatment that can't be immediately applied.
Beginning Web Development with Perl
Beginning Perl Web Development: From Novice to Professional introduces you to the world of Perl Internet application development. This book tackles all areas crucial to developing your first web applications and includes a powerful combination of real-world examples coupled with advice. Topics range from serving and consuming RSS feeds, to monitoring Internet servers, to interfacing with e-mail. You'll learn how to use Perl with ancillary packages like Mason and Nagios. Though not version-specific, this book is an ideal read if you have had some grounding in Perl basics and now want to move into the world of web application development. Author Steve Suehring emphasizes the security implications of Perl, drawing on years of experience teaching readers how to think safe, avoid common pitfalls, and produce well-planned, secure code.
Beginning Visual Web Programming in VB .NET : From novice to professional
Beginning Web Programming in VB .NET: From Novice to Professional will teach you the fundamentals of the web environment and how Visual Studio .NET (VS .NET) makes it accessible to VB programmers. You'll build a working website that demonstrates all the elements of a VB web application. Author Daniel Cazzulino takes a step-by-step approach to each example to explore the essential technologies and how VS .NET helps to integrate them into a highly interactive, attractive web application.
Beginning Visual Web Developer 2005 Express : From novice to professional
The primary goal of this book is to demonstrate Visual Web Developer 2005 Expresss effectiveness when developing applications. The secondary goal is to examine how coding best-practices can be applied with this new product. Beginning Visual Web Developer 2005 Express provides a rigorous overview of the application: how it operates, how it compares to the other versions of Visual Studio .NET 2005 now available, and the best way to use it.
Beginning Visual C# 2005 Express ed. : From novice to professional
Wright took the same approach with this book that he did with the VB titles, and inside you'll find a fast–paced guide to the essentials to get you programming fast. You'll learn the C# language and the tools Visual C# 2005 Express provides. He covers everything from simple console programs to code that talks to the Internet, and even how to write your own database programs. Whatever your reasons for wanting to learn to program with C#, this book will get you where you want to be quickly, and hopefully with a smile on your face. So dive in and change the way you use computers forever.
Beginning Ubuntu Linux : From novice to professional
Beginning Ubuntu Linux is the perfect guide for those switching to the world's favorite Linux. The new edition has been thoroughly updated to cover technology introduced in the 6.10 release. You'll learn how to install Linux, set up your hardware and software, customize the desktop experience, browse the Web and send/receive e-mail, play back audio and video, edit digital images, use the OpenOffice.org office suite, and more.



















