Bioinformatics of genome regulation and structure II
The conference was organized by the Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. The material covers the most recent topics in bioinformatics, including (i) regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; (ii) large-scale genome analysis and functional annotation; (iii) gene structure detection and prediction; (iv) comparative and evolutionary genomics; (v) computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure- function organization of genomic DNA, RNA, and proteins; (vi) gene networks, signal transduction pathways, and genetically controlled metabolic pathways: databases, knowledge bases, computer analysis, and modeling; principles of organization, operation, and evolution; (vii) data warehousing, knowledge discovery and data mining; and (viii) analysis of basic patterns of genome operation, organization, and evolution.
25 Years of P53 Research
Communication, awareness and access to information: Given the complexity of the field and the fact that data pertaining to each particular aspects of p53 biology or deregulation are scattered in many different publications, it is extremely difficult to access the full scale of relevant information of any specific p53-related topic. This book may help in this task by putting into perspective both general considerations on the p53 pathway and more specific information on various aspects of p53. In the longer term, however, open access to p53 complexity will require the development of knowledge bases accessible through the web and using simple navigation tools to guide users towards the specific information they need. Several efforts are currently being developed in that direction. They need to be strenghtened and better integrated within the rapidly growing galaxy of web-based information sources on molecular and individual variations in cancer. 2. Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard, universally accepted assays to measure critical p53 protein functions.
Applications and Innovations in Intelligent Systems XV ; Proceedings of AI-2007, the Twenty-seventh SGAI International Conference on Innovative Techniques and Applications of Artificial Intelligence
The papers in this volume are the refereed application papers presented at AI-2007, the Twenty-seventh SGAI International Conference on Innovative Techniques and Applications of Artificial Intelligence, held in Cambridge in December 2007.
An Introduction to Knowledge Engineering
Knowledge Engineering refers to the development of systems that use knowledge, rather than data, to solve many novel computing problems. This is achieved by the application of computing techniques, closely associated with human cognitive processes, for transforming data into knowledge. An Introduction to Knowledge Engineering presents a simple but detailed exploration of current and established work in the field.
Management of Convergence in Innovation : Strategies and Capabilities for Value Creation Beyond Blurring Industry Boundaries
Throughout the past decade, the phenomenon of technological convergence has increasingly gained managerial attention. In this special form of technological change, the coming-together of previously distinct knowledge bases gives rise to the creation of new applications and business models. When such innovations emerge at the intersection of industries, the resulting creative destruction may exceed previously established industry boundaries. As a consequence, convergence does not only promise the creation of new value, but may imply significant disruptions to established industries. Based on investigating 26 firms within the ICT industry, this book highlights implications of the convergence phenomenon on firms’ innovation management practices, and derives strategic guidelines for building and sustaining business models beyond blurring industry boundaries.
Knowledge-Based Virtual Education : User-Centred Paradigms
The book covers a multitude of important issues on the subject of "Innovations in Knowledge-Based Virtual Education ", aiming at researchers and practitioners from academia, industry, and government. The carefully selected contributions report on research, development and real-world experiences of virtual education.
Advances and Innovations in Systems, Computing Sciences and Software Engineering
Acollection of world class paper articles addressing the following topics: Image and Pattern Recognition: Compression, Image processing, Signal Processing Architectures, Signal Processing for Communication, Signal Processing Implementation, Speech Compression, and Video Coding Architectures. Languages and Systems: Algorithms, Databases, Embedded Systems and Applications, File Systems and I/O, Geographical Information Systems, Kernel and OS Structures, Knowledge Based Systems, Modeling and Simulation, Object Based Software Engineering, Programming Languages, and Programming Models and tools. Parallel Processing: Distributed Scheduling, Multiprocessing, Real-time Systems, Simulation Modeling and Development, and Web Applications. New trends in computing: Computers for People of Special Needs, Fuzzy Inference, Human Computer Interaction, Incremental Learning, Internet-based Computing Models, Machine Intelligence, Natural Language Processing, Neural Networks, and Online Decision Support System.
Activity and Sign : Grounding Mathematics Education
This volume provides new sources of knowledge based on Michael Otte’s fundamental insight that understanding the problems of mathematics education – how to teach, how to learn, how to communicate, how to do, and how to represent mathematics – depends on means, mainly philosophical and semiotic, that have to be created first of all, and to be reflected from the perspectives of a multitude of diverse disciplines.







