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الصفحة 3
الصفحة 3
An introduction to generative drug discovery
Describes the state‑of‑the‑art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology. It will provide a foundation for those new to the field as well as those that may already have some experience of its utility. With contributions from scientists in both academia and industry ‘Introduction to Generative Drug Discovery’ may represent one of the earliest if not the first book to focus on this topic.
Allergy in Practice
This book reflects the rich personal experience of a German allergist with international training and reputation, who is active in immunology and allergy research and practice for almost 30 years. In this book, not only IgE-mediated allergic reactions are covered but all other kinds of allergies such as atopic eczema, contact dermatitis, drug eruptions, anaphylaxis and food allergies are equally represented as well as psychosomatic aspects and problems of environmental intolerances.
Agroecological transitions : From theory to practice in local participatory design
There is wide agreement on the need to change the prevalent agricultural models, given their negative impacts and their incompatibility with current societal issues. Agroecological transition has been promoted as a potential solution to the ecological, social and economic problems generated by these models. It however involves a systemic, multi-scale and transdisciplinary process. Due to this complexity, the overall picture of what farms and food systems “actually are” and “might be” may not be apparent at the individual level. Yet individuals’ knowledge and values provide complementary insights on how to proceed in deepening ecological modernisation. Expertise can also provide landmarks to be considered in that process. Because local stakeholders’ experience and skills are key resources in the adaptation and adoption of agroecological transition, new conceptual and methodological frameworks and tools have to be developed to support them in the design process of such a complex transition. This book presents feedback from the ‘Territorial Agroecological Transition in Action’- TATA-BOX research project, which was devoted to these specific issues.
Aesthetic Surgery of the Facial Mosaic
This authoritative reference book assembles the experience of an international faculty of authors, each of whom has performed several thousand facelifts, i.e. procedures to rejuvenate and harmonize the human face. All procedures in this regard are covered and the text is accompanied by extensive artwork and photographs. The authors share their experience, including tips and tricks, as well as ways to avoid complications and pitfalls. Special emphasis is given to the concept of looking at the face as a mosaic, i.e. treating its individual parts in a harmonic way and maintaining mimic units. Combining different methods.
Advances and Technical Standards in Neurosurgery ; Vol. 30
This series, sponsored by the European Association of Neurosurgical Societies, has already become a classic. In general, one volume is published per year. The Advances section presents fields of neurosurgery and related areas in which important recent progress has been made. The Technical Standards section features detailed descriptions of standard procedures to assist young neurosurgeons in their post-graduate training. The contributions are written by experienced clinicians and are reviewed by all members of the Editorial Board.
Advanced Techniques in Soil Microbiology
"Advanced Techniques in Soil Microbiology" presents a wide range of biotechnological methods for application in soil microbiology analysis. These include all essential methods involving molecular biology, immunology, microbiology, and structural biology, such as transcriptome analysis, RNAi technology, molecular matchmaking, RAPD, T-RFLP and FT/MS. The techniques and procedures have been selected with the aim of offering practical guides for immediate use in the laboratory. The systems investigated range from individual molecules and cells to entire eukaryotic organisms, with a focus on bacteria, fungi, mycorrhiza, and higher plants. This volume of state-of-the-art, practice oriented methods will be of great use both to the first-timer and to the experienced scientist.
Adrenal Glands : Diagnostic Aspects and Surgical Therapy
Surgery of the Adrenal Glands is a comprehensive medical textbook that includes everything that a surgeon, but for all purposes any physicain or medical student, may want to find on adrenal surgery in a friendly, up to date, evidence based manner. 30 of the most renowned names in the field of adrenal surgery from the US and Europe draw on their experience in exploring diagnosis, indications for surgery, choice of operation and operative techniques, and surgical outcomes for every major adrenal condition. Over 200 exquisite illustrations, ranging from intraoperative photographs, line drawings, diagnostic images, pathology slides, tables and graphs are available to make each case discussed comprehensible and easy to follow. Traditional and novel therapeutic recommendations are introduced and the latest developments in minimal-access operative techniques are discussed and reviewed. Finally, the best approaches in dealing with challenging conditions such as adrenal incidentaloma, subclinical Cushing's syndrom, Congenital Adrenal Hyperplasia, Mineralcorticoid Express Syndrome, Extraadrenal and Malignant Pheochromocytoma are discussed.
Abord clinique en urologie = Clinical approach in urology
Seduced by the idea of commenting on the clinical experience they have acquired during their career, the authors have deliberately approached their specialty by describing the symptoms that give the chapters their titles. They nevertheless described the differential diagnoses, the diseases involved and the treatments. After a chapter devoted to the examination of the patient, including the detours of the interrogation, back pain or scrotal pain are analyzed. The authors then turned to voiding disorders and their causes. The peculiarities of hematuria, depending on their level of origin, are described and commented on. The semiology of tumor masses is carefully detailed and, conversely, the problem of prostate cancer screening by PSA is dealt with in a separate chapter. Erectile dysfunction and penile diseases are the last chapters. In the line of the “Clinical approach” collection, this manual is easy to consult thanks to a detailed index, easy to understand because it is written in clear language and, moreover, well illustrated (21 diagrams and 2 tables). In this little book, the authors have approached urology from a perspective close to how patients feel.
A History of Limb Amputation
This book traces humanity’s long experience of natural amputations due to congenital absence, disease, frostbite, toxins, domestic and wild animal trauma, and for non-medical reasons related to punitive, ritual, and legal actions, ultimately leading to the development of elective surgical amputation. While the evolution of surgical techniques forms a major chapter in the book, many ancillary problems are addressed including the control of hemorrhage and infection, the approach to pain relief, the development of suitable instruments and equipment, and the invention of prostheses, all suitably illuminated with case histories and relevant illustrations. In addition, alternative procedures designed to avoid amputation, increasingly important in the last two centuries, are debated, and factors associated with self-amputation in extremis, not rare according to press reports, are also examined. A separate chapter considers the philosophy and interpretations of society, patients, and surgeons faced with amputation, particularly before anesthesia.
Law, surveillance and the humanities
Explores key issues such as the use and legitimacy of surveillance to address a global health crisis, the role of surveillance in the experience of indigenous peoples in post-colonial societies, how surveillance interacts with gender, race, ethnicity, and social class, and the interaction between technology, surveillance, and changing attitudes to expression. how philosophy and sociology can help to correct biases and law and politics can offer new approaches to the legitimacy, use and implications of surveillance.
China and the World in a Changing Context : Perspectives from Ambassadors to China
This book aims to present an overview of China and the world from diverse angles. It brings together essays by ambassadors to China on a range of bilateral and multilateral issues, including trade and investment, regional economic cooperation, sustainable development, technology and innovation, and entrepreneurship. Given their familiarity with China and extensive international experience, the insights of these ambassadors are useful for policymakers, academics, entrepreneurs, students, and anyone trying to make sense of our rapidly changing world.
Managing Risk and Information Security : Protect to Enable
Examine the evolving enterprise security landscape and discover how to manage and survive risk. While based primarily on the author’s experience and insights at major companies where he has served as CISO and CSPO, the book also includes many examples from other well-known companies and provides guidance for a management-level audience. Managing Risk and Information Security provides thought leadership in the increasingly important area of enterprise information risk and security. It describes the changing risk environment and why a fresh approach to information security is needed. Because almost every aspect of an enterprise is now dependent on technology not only for internal operations but increasing as a part of product or service creation, the focus of IT security must shift from locking down assets to enabling the business while managing and surviving risk. This edition discusses business risk from a broader perspective, including privacy and regulatory considerations. It describes the increasing number of threats and vulnerabilities and offers strategies for developing solutions. These include discussions of how enterprises can take advantage of new and emerging technologies—such as social media and the huge proliferation of Internet-enabled devices—while minimizing risk.
Managing Humans : Biting and Humorous Tales of a Software Engineering Manager
Managing Humans is a selection of the best essays from Michael Lopp's web site, Rands in Repose. Drawing on Lopp's management experiences at Apple, Netscape, Symantec, and Borland, this book is full of stories based on companies in the Silicon Valley where people have been known to yell at each other. It is a place full of dysfunctional bright people who are in an incredible hurry to find the next big thing so they can strike it rich and then do it all over again. Among these people are managers, a strange breed of people who through a mystical organizational ritual have been given power over your future and your bank account.
Machine Learning for Cyber Physical Systems : Selected papers from the International Conference ML4CPS 2020
Presents new approaches to Machine Learning for Cyber Physical Systems, experiences and visions. It contains selected papers from the fifth international Conference ML4CPS – Machine Learning for Cyber Physical Systems, which was held in Berlin, March 12-13, 2020.
Machine Learning and Cognitive Computing for Mobile Communications and Wireless Networks
Communication and network technology has witnessed recent rapid development and numerous information services and applications have been developed globally. These technologies have high impact on society and the way people are leading their lives. The advancement in technology has undoubtedly improved the quality of service and user experience yet a lot needs to be still done. Some areas that still need improvement include seamless wide-area coverage, high-capacity hot-spots, low-power massive-connections, low-latency and high-reliability and so on. Thus, it is highly desirable to develop smart technologies for communication to improve the overall services and management of wireless communication. Machine learning and cognitive computing have converged to give some groundbreaking solutions for smart machines. With these two technologies coming together, the machines can acquire the ability to reason similar to the human brain. The research area of machine learning and cognitive computing cover many fields like psychology, biology, signal processing, physics, information theory, mathematics, and statistics that can be used effectively for topology management. Therefore, the utilization of machine learning techniques like data analytics and cognitive power will lead to better performance of communication and wireless systems.
Long-Term Preservation of Digital Documents : Principles and Practices
Key to our culture is that we can disseminate information, and then maintain and access it over time. While we are rapidly advancing from vulnerable physical solutions to superior, digital media, preserving and using data over the long term involves complicated research challenges and organization efforts. Uwe Borghoff and his coauthors address the problem of storing, reading, and using digital data for periods longer than 50 years. They briefly describe several markup and document description languages like TIFF, PDF, HTML, and XML, explain the most important techniques such as migration and emulation, and present the OAIS (Open Archival Information System) Reference Model. To complement this background information on the technology issues the authors present the most relevant international preservation projects, such as the Dublin Core Metadata Initiative, and experiences from sample projects run by the Cornell University Library and the National Library of the Netherlands. A rated survey list of available systems and tools completes the book.
Logic Programming with Prolog
Logic Programming is the name given to a distinctive style of programming, very different from that of conventional programming languages such as C++ and Java. By far the most widely used Logic Programming language is Prolog. Prolog is a good choice for developing complex applications, especially in the field of Artificial Intelligence. This book does not assume that the reader is an experienced programmer or has a background in Mathematics, Logic or Artificial Intelligence. It starts from scratch and aims to arrive at the point where quite powerful programs can be written in the language. It is intended both as a textbook for an introductory course and as a self-study book. On completion the reader will know enough to use Prolog in their own research or practical projects. Each chapter has self-assessment exercises so that the reader may check their own progress. A glossary of the technical terms used completes the book.
Learn BlackBerry 10 App Development : A Cascades-Driven Approach
Learn how to leverage the BlackBerry 10 Cascades framework to create rich native applications. Learn BlackBerry 10 App Development gives you a solid foundation for creating BlackBerry 10 apps efficiently. Along the way, you will learn how to use QML and JavaScript for designing your app’s UI, and C++/Qt for the application logic. No prior knowledge of C++ is assumed and the book covers the fundamental aspects of the language for writing BlackBerry 10 apps. Also a particular emphasis is put on how to create a visually enticing user experience with the Cascades framework, which is based on Qt and QML.
Java Design Patterns : A Hands-On Experience with Real-World Examples
Covers classical design patterns with the latest editions of Java and Eclipse Includes implementation of the Java design patterns in real-world applications Each chapter has a Q&A section to help you understand the pros and cons of each design pattern
Issues in Multi-Agent Systems : The AgentCities.ES Experience
The purpose of this book is to present current status of this technology by looking at its application in different domains, such as electronic markets, e-tourism, ambience intelligence, and complex system analysis.It starts by discussing software engineering issues for the development of multi-agent systems, how much it costs to build a multi-agent system, and which methods and tools are currently available. Next chapters present some of the most relevant aspects that are considered for the development of multi-agent systems.
