Bioactive Confirmation II
Specific binding of a ligand to a receptor is a key step in a variety of biol- ical processes, such as immune reactions, enzyme cascades, or intracellular transport processes. The ligand-receptor terminology implies that the rec- tor molecule is signi?cantly larger than the ligand, and the term "bioactive conformation" usually characterizes the conformation of a ligand when it is bound to a receptor. In a more general sense, bioactive conformation applies toanymoleculeinabiologicallyrelevantboundstateregardlessofsizecons- erations. Mostofthecontributions tothisbookaddressligandsthat aremuch smaller than their receptors. X-ray crystallography and high resolution NMR spectroscopy are the two main experimental techniques used to study bioactive conformations. The- fore, the twovolumes ofthisbookcover approachesthat use either ofthetwo techniques, or a combination thereof.
Binocular astronomy
Anyone who has used a binocular telescope or even wide-field binoculars to look at the night sky will know just how breathtakingly beautiful the view can be when you observe with both eyes. Observing galaxies and nebulae with ‘regular’ prismatic binoculars is just a beginning. Binocular eyepieces and adapters can be added to almost any commercially-made astronomical telescope, and of course specialized astronomical binoculars can be assembled or purchased complete. These range from modest instruments to giants that are basically two large telescopes mounted together. Binocular Astronomy contains everything you’ll need to know about this exciting branch of astronomical observing.
Binary Rare Earth Oxides
The book begins with a brief introduction to binary rare earth oxides, their physical and chemical stabilities, polymorphism, crystal structures and phase transformation and the association with current applications. The book goes on to present the band structure of the oxides using several quantum chemical calculations, which belong to a newly developed area in the binary rare earth oxides. Central to this chapter are the characterizations of electrical, magnetic and optical properties, as well as details of single crystal growth and particle preparation methods that have progressed in recent years. Later chapters concentrate on thermo-chemical properties and trace determination techniques. The final chapter contains a variety of useful applications in various fields such as phosphors, glass abrasives, automotive catalysts, fuel cells, solid electrolytes, sunscreens, iron steels, and biological materials.
Bifurcations, Instabilities, Degradation in Geomechanics
Leading international researchers and practitioners of bifurcations and instabilities in geomechanics debate the developments and applications which have occurred over the last few decades. The topics covered include modeling of bifurcation, structural failure of geomaterials and geostructures, advanced analytical, numerical and experimental techniques, and application and development of generalised continuum models etc. In addition analytical solutions, numerical methods, experimental techniques, and case histories are presented. Beside fundamental research findings, applications in geotechnical, petroleum, mining, and bulk materials engineering are emphasised.
Bayesian reliability
Bayesian Reliability presents modern methods and techniques for analyzing reliability data from a Bayesian perspective. The adoption and application of Bayesian methods in virtually all branches of science and engineering have significantly increased over the past few decades. This increase is largely due to advances in simulation-based computational tools for implementing Bayesian methods. The authors extensively use such tools throughout this book, focusing on assessing the reliability of components and systems with particular attention to hierarchical models and models incorporating explanatory variables. Such models include failure time regression models, accelerated testing models, and degradation models. The authors pay special attention to Bayesian goodness-of-fit testing, model validation, reliability test design, and assurance test planning. Throughout the book, the authors use Markov chain Monte Carlo (MCMC) algorithms for implementing Bayesian analyses--algorithms that make the Bayesian approach to reliability computationally feasible and conceptually straightforward.
Axial flux permanent magnet brushless machines
Axial Flux Permanent Magnet (AFPM) brushless machines are modern electrical machines with a lot of advantageous merits over their conventional counterparts. They are increasingly used in power generation, domestic appliances, industrial drives, electric vehicles, and marine propulsion drives and many other applications. This book deals with the analysis, construction, design, optimisation, control and applications of AFPM machines. The authors present their own research results, as well as significant research contributions made by others. This monograph will be of interest to electrical engineers and other engineers involved in the design and application of AFPM brushless machine drives. It will be an important resource for researchers and graduate students in the field of electrical machine and drives.
Avalanche Dynamics : Dynamics of Rapid Flows of Dense Granular Avalanches
Avalanches, debris, mudflows and landslides are common and natural phenomena that occur worldwide, predominantly in mountainous regions. With an emphasis on snow avalanches, this book sets out to provide a survey and discussion about the motion of avalanche-like flows from initiation to run out. An important aspect of this book is the formulation and investigation of a simple but appropriate continuum mechanical model for the realistic prediction of geophysical flows of granular material. This will help the practitioners in the field to better understand the physical input and provide them with a tool for their work. Originating from many lectures the authors have given over the years, this instructive volume brings the reader to the forefront of research - an aim also supported by an extensive bibliogrpahy of almost 500 entries.
Automatic Differentiation : Applications, Theory, and Implementations
This collection covers the state of the art in automatic differentiation theory and practice. Practitioners and students will learn about advances in automatic differentiation techniques and strategies for the implementation of robust and powerful tools. Computational scientists and engineers will benefit from the discussion of applications, which provide insight into effective strategies for using automatic differentiation for design optimization, sensitivity analysis, and uncertainty quantification.
Auralization : Fundamentals of acoustics, modelling, simulation, algorithms and acoustic virtual reality
"Auralization" is the technique of creation and reproduction of sound on the basis of computer data. With this tool is it possible to predict the character of sound signals which are generated at the source and modified by reinforcement, propagation and transmission in systems such as rooms, buildings, vehicles or other technical devices. This book is organized as a comprehensive collection of the basics of sound and vibration, acoustic modelling, simulation, signal processing and audio reproduction. Implementations of the auralization technique are described using examples drawn from various fields in acoustic’s research and engineering, architecture, sound design and virtual reality.
Atomistic modeling of materials failure
Atomistic Modeling of Materials Failure is an introduction to molecular and atomistic modeling techniques applied to solid deformation and fracture. Focusing on a variety of brittle, ductile and geometrically confined materials, this detailed overview includes computational methods at the atomic scale, and describes how these techniques can be used to model the dynamics of cracks, dislocations and other deformation mechanisms.
Atomic and Nuclear Analytical Methods : XRF, Mössbauer, XPS, NAA and Ion-Beam Spectroscopic Techniques
This book is a blend of analytical methods based on the phenomenon of atomic and nuclear physics. It comprises comprehensive presentations about X-ray Fluorescence (XRF), Mössbauer Spectroscopy (MS), X-ray Photoelectron Spectroscopy (XPS), Neutron- Activation Analysis (NAA), Particle Induced X-ray Emission Analysis (PIXE), Rutherford Backscattering Analysis (RBS), Elastic Recoil Detection (ERD), Nuclear Reaction Analysis (NRA), Particle Induced Gamma-ray Emission Analysis (PIGE), and Accelerator Mass Spectrometry (AMS). These techniques are commonly applied in the fields of medicine, biology, environmental studies, archaeology or geology et al. and pursued in major international research laboratories.
Astroparticle physics
The book describes the branch of astrophysics in which processes in the universe are investigated with experimental methods known from particle physics experiments. After a historical introduction to the basics of elementary particles, their interactions and the relevant detection techniques are described. The main body of the book concerns cosmic rays. The modern aspects of astroparticle physics are described in a chapter on cosmology. The book provides an orientation in the field of astroparticle physics that many beginners might look for. The physics issues are presented with little mathematics, and the results are illustrated by many diagrams. The reader has a chance to enter this field of astrophysics with a book that closes the gap between expert and popular level.
Astronomical image and data analysis
With information and scale as central themes, this comprehensive survey explains how to handle real problems in astronomical data analysis using a modern arsenal of powerful techniques. It treats those innovative methods of image, signal, and data processing that are proving to be both effective and widely relevant. The coverage includes chapters or appendices on: detection and filtering; image compression; multichannel, multiscale, and catalog data analytical methods; wavelets transforms, Picard iteration, and software tools. This second edition of Starck and Murtagh's highly appreciated reference again deals with topics that are at or beyond the state of the art. It presents material which is more algorithmically oriented than most alternatives and broaches new areas like ridgelet and curvelet transforms. Throughout the book various additions and updates have been made.
Assessing and Managing Earthquake Risk : Geo-scientific and Engineering Knowledge for Earthquake Risk Mitigation: developments, tools, techniques
This book points out the need of a multidisciplinary approach in the field of risk assessment and management. It provides an overview of the problems, approaches and common practices directly related to earthquake risk mitigation and, in particular, to the preparation of earthquake emergency plans. Written by a team of specialists from different disciplines, the authors worked together extensively in order to create unity and continuity in the text as a whole. Each topic is illustrated with examples of actual applications taken from the bibliography – including websites with available relevant information. Case studies and information on some relevant international projects are given.
Assertion-Based Design
Chapter 3 Specifying RTL Properties 61 3. 3 Declarative versus procedural 67 3. 3 RTL assertion specification techniques 68 RTL invariant assertions 69 3. 2 Declaring properties with PSL 72 RTL cycle related assertions 73 3. 3 3. 1 Immediate assertions 84 3. 3 System functions 95 3. 3 Assertions across simulation time slots 111 4.
Aspects of Mathematical Finance
Considering the stupendous gain in importance, in the banking and insurance industries since the early 1990’s, of mathematical methodology, especially probabilistic methodology, it was a very natural idea for the French "Académie des Sciences" to propose a series of public lectures, accessible to an educated audience, to promote a wider understanding for some of the fundamental ideas, techniques and new tools of the financial industries. These lectures were given at the "Académie des Sciences" in Paris by internationally renowned experts in mathematical finance, and later written up for this volume which develops, in simple yet rigorous terms, some challenging topics such as risk measures, the notion of arbitrage, dynamic models involving fundamental stochastic processes like Brownian motion and Lévy processes.
Artificial neural networks in Vehicular Pollution Modelling
Artificial neural networks (ANNs), which are parallel computational models, comprising of interconnected adaptive processing units (neurons) have the capability to predict accurately the dispersive behavior of vehicular pollutants under complex environmental conditions. This book aims at describing step-by-step procedure for formulation and development of ANN based VP models considering meteorological and traffic parameters. The model predictions are compared with existing line source deterministic/statistical based models to establish the efficacy of the ANN technique in explaining frequent dispersion complexities in urban areas. The book is very useful for hardcore professionals and researchers working in problems associated with urban air pollution management and control.
Artificial neural networks for the Modelling and Fault Diagnosis of Technical Processes
In this book, a wide spectrum of fault diagnosis techniques have been developed. A major category of fault diagnosis techniques is the model based one, where an analytical model of the plant to be monitored is assumed to be available.
Artificial intelligence techniques for computer graphics
This volume contains both invited and selected extended papers from the last 3IA Conference (3IA’2008), together with an introduction presenting the area of Intelligent Computer Graphics and various Computer Graphics areas where introduction of intelligent techniques permitted to resolve important problems.
Artificial intelligence in recognition and classification of astrophysical and medical images
This book presents innovative techniques in Recognition and Classification of Astrophysical and Medical Images. The contents include: Introduction to pattern recognition and classification in astrophysical and medical images. Image standardization and enhancement. Region-based methods for pattern recognition in medical and astrophysical images. Advanced information processing using statistical methods. Feature recognition and classification using spectral method



















