تحسين النتائح
ترتيب حسب
من
الى
الصفحة 16
الصفحة 16
Adhesion Molecules : Function and Inhibition
Inflammatory cell recruitment requires the concerted action of at least five major sets of adhesion molecules: integrins, immunoglobulin-like molecules, selectins, carbohydrate structures serving as selectin ligands, and certain ectoenzymes. This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future approaches is also provided. The book is of interest to clinicians and scientists from immunology, physiology, cancer research, rheumatology, allergology, infectious diseases, gastroenterology, pulmonology and cardiology.
Adaptogens : Herbs for strength, stamina, and stress relief
Includes a Materia Medica with monographs covering 25 adaptogens, including eleuthero, ginseng, rhodiola, schisandra, ashwagandha, licorice, shatavari, reishi, and holy basil, as well as complementary nervines, restorative tonics, and nootropics Explains how adaptogens increase the body's resistance to adverse influences, increase energy and stamina, and counter the effects of age and stress on the body Details the actions, properties, preparation, and dosage for each herb and their uses in Ayurveda and Chinese medicine and as remedies for animals Every day our bodies strive to adapt and stay balanced, energized, and healthy, yet chronic stress and the resulting elevation of stress hormones such as cortisol have been shown to be major factors behind not only fatigue and weight gain but also many chronic and degenerative diseases
Adaptation to Life at High Salt Concentrations in Archaea, Bacteria, and Eukarya
This book complements “Halophilic Microorganisms”, edited by A. Ventosa and published by Springer-Verlag (2004), “Halophilic Microorganism and their Environments” by A. Oren (2002), published by Kluwer Academic Publishers as volume 5 of “Cellular Origins, Life in Extreme Habitats and Astrobiology” (COLE), and “Microbiology and Biogeochemistry of Hypersaline Environments” edited by A. Oren, and published by CRC Press, Boca Raton (1999).
Acute Promyelocytic Leukemia : Molecular Genetics, Mouse Models and Targeted Therapy
Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy.
Acute Myelogenous Leukemia
The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. Bringing together new concepts and findings in the basic and clinical science of AML, the book emphasizes the molecular basis for new therapies that stand to have the greatest potential impact on the clinical face of these diseases. The text provides insights into selected novel strategies currently and prospectively being developed, including interruption of specific signal transduction pathways, modulation of gene expression, attempts to reinstate differentiation, and immunomodulation.
Acute Ischemic Stroke : Imaging and Intervention
Acute Ischemic Stroke: Imaging and Intervention is a comprehensive presentation of the state-of-the-art in the diagnosis and treatment of acute ischemic stroke. This book offers a practical review of recent advances in stroke neuroimaging, and the latest therapeutic options for this disease.
Acute Endocrinology : From Cause to Consequence
The integration of endocrinology in critical care medicine has led to new experimental and clinical data on the complex endocrine and metabolic derangements accompanying non-endocrine severe illnesses. The joining of these two disciplines has generated important novel insights with significant clinical implications. Acute Endocrinology: From Cause to Consequence compiles these new findings into an important and highly relevant new resource.
Actualités en rééducation des maladies neuro-musculaires de ladulte = News in rehabilitation of neuro-muscular diseases in adults
Neuro-muscular diseases include congenital or acquired pathologies of the muscle and the peripheral nerve. This book covers all the care of the adult patient with such a condition.
Actin-Binding Proteins and Disease
This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin ¾4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.
Acetylsalicylic Acid
Contains the latest results of clinical and pharmacological research on Acetylsalicylic acid, addressing the multiple pharmacological properties of this famous drug with a balanced view on their translation into clinical practice, including prevention and treatment of cardiovascular diseases, thromboinflammation and colorectal cancer. Understandable for clinicians, pharmacists, biomedical researchers and pharmacologists alike.
Abord clinique des urgences traumatiques au cabinet du généraliste = Clinical approach to traumatic emergencies in the general practitioner's office
Cet ouvrage a été conçu comme une aide pour le médecin généraliste, confronté quotidiennement à la pathologie traumatique. Les deux auteurs, urgentistes expérimentés, apportent des réponses claires, concises et pratiques aux problèmes que posent les lésions traumatiques. Des gestes simples, un abord clinique détaillé, la nécessité de recourir ou non à des examens complémentaires ou à un avis spécialisé sont ici expliqués et justifiés. Le style est précis, concis, et un lexique complète les définitions et les matériels cités dans le texte. Les auteurs se sont entourés des avis de généralistes et de spécialistes pour définir des conduites à tenir simples et compatibles avec les nécessités du terrain.
Abord clinique des malades de lalcool : En médecine générale = Clinical approach to patients with alcoholism : In general medicine
Les médecins généralistes sont destinataires d’un grand nombre d’informations sur l’alcool, son usage et ses conséquences pathologiques immédiates ou potentielles. Ces connaissances, émanant de médecins le plus souvent hospitaliers et spécialisés, ont conduit à des recommandations destinées à guider les médecins généralistes dans le repérage des malades de l’alcool et leur prise en charge thérapeutique. Cependant, la pertinence et l’applicabilité de la plupart de ces recommandations sont peu ou mal évaluées dans la pratique de la médecine générale. De ce fait, les médecins généralistes, parfois à l’encontre des recommandations, sont amenés à élaborer des concepts et des pratiques propres à leur clientèle et à leurs conditions de travail. L’originalité de ce livre vient de la confrontation des connaissances et des pratiques de deux médecins, soignant des malades de l’alcool dans des structures différentes.
Abeta Peptide and Alzheimers Disease : Celebrating a Century of Research
Abeta Peptide and Alzheimer’s Disease summarizes current knowledge of beta-amyloid peptide (Aß) and its role as the major culprit in Alzheimer’s Disease (AD), shown by recent advances in genetics and brain biochemistry.the book covers fundamental biochemical studies on the Aß peptide, the genetic impact on Aß expression and processing, and various AD therapeutic strategies that target Aß. Although specifically focusing on Aß and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases.
A Time for Metabolism and Hormones
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
A Sea Change: The Exclusive Economic Zone and Governance Institutions for Living Marine Resources
A Sea Change in a Changing Sea The oceans, seas and coastal areas encompass over 70% of the earth’s surface. They are a critical driver of the earth’s hydrologic cycle and climate system, important for c- merce, transport, and tourism, a source of economically important living marine resources, minerals such as hydrocarbons, as well as new pharmaceutical compounds. The marine environment provides essential habitats for thousands of marine living 1 2 resources, which in turn contribute significantly to global food security, employment, 3 and trade. Overall, the sea’s contribution to human welfare, in terms of market and non-market resources and environmental services, has been estimated at US$21 trillion/year (Costanza, 2000). However, despite the importance of the ocean realm to humans, there is a growing sense that human impacts are destabilizing this system. Some experts believe that current fishing levels are approaching or exceeding the total 4 productivity of the ocean ecosystem (National Research Council, 1999).
A Reappraisal of the Ascending Systems in Man, with Emphasis on the Medial Lemniscus
Based on material assembled by Dr Jaap HR Schoen who was one of the few neuroanatomists to apply the Nauta method to human material. Gaining insight in the consequences of longitudinal damage to the human spinal cord is necessary before reimplantation of the avulsed rootlets or an autologous transplant can be performed in man.
3D printing of pharmaceutical and drug delivery devices progress from bench to bedside
Discover the latest, fast-developing technology to help move towards more cost-effective, small-batch, decentralized manufacturing of personalized systems . 3D printing has revolutionized manufacturing. Its precision and flexibility have enabled the large-scale production of materials and devices too complex for conventional industrial manufacturing. This has been particularly revolutionary in the field of pharmaceutical production, where 3D printing is being integrated into the manufacture of both drugs and drug delivery devices. It has never been more important for industry professionals to understand this form of production.
Linked Democracy : Foundations, Tools, and Applications
This book shows the factors linking information flow, social intelligence, rights management and modelling with epistemic democracy, offering licensed linked data along with information about the rights involved. This model of democracy for the web of data brings new challenges for the social organisation of knowledge, collective innovation, and the coordination of actions. Licensed linked data, licensed linguistic linked data, right expression languages, semantic web regulatory models, electronic institutions, artificial socio-cognitive systems are examples of regulatory and institutional design (regulations by design). The web has been massively populated with both data and services, and semantically structured data, the linked data cloud, facilitates and fosters human-machine interaction. Linked data aims to create ecosystems to make it possible to browse, discover, exploit and reuse data sets for applications. Rights Expression Languages semi-automatically regulate the use and reuse of content.
Liberal Democracy : Prosperity through Freedom
Aims to show which factors have been decisive in the rise of successful countries. Never before have so many people been so well off. However, prosperity is not a law of nature; it has to be worked for. A liberal economy stands at the forefront of this success – not as a political system, but as a set of economic rules promoting competition, which in turn leads to innovation, research and enormous productivity.
Competition Authorities in South Eastern Europe : Building Institutions in Emerging Markets
Provides answers to key open questions concerning competition policy in emerging economies, with a focus on South Eastern Europe. The contributions address two major issues. One is the design of competition policy and the national competition authorities that enforce it, including the topics of competition advocacy and state aid control; the other is the use of economic methods in competition law enforcement, especially in the cases of relevant market definition and merger control. Many lessons learned in the countries of South Eastern Europe can be applied to the emerging markets of other regions. As such, the findings presented here will be highly relevant for officials and staff at national competition authorities, advisers to legislators shaping national competition policy, competition law professionals, and university students alike.
