الصفحة 15
الصفحة 15
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Aging and the Heart : A Post-Genomic View

In this book, the genetic and molecular basis of cardiovascular aging will be discussed. In addition, a comprehensive assessment of the bioenergetic changes that occur in human and animal models of cardiac aging as well as current diagnostic and future therapeutic modalities will be undertaken.

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Aging and Chronic Disorders

Aging and Chronic Disorders brings the most up-to-date answers into clear, readable focus. Focusing on the most prevalent conditions affecting older adults (diabetes, cardiovascular disease, cancer, osteoporosis, osteoarthritis, rheumatoid arthritis, low back pain, and fibromyalgia), Morewitz and Goldstein analyze disabilities and risk factors, stressors and coping strategies, treatment and rehabilitation methods, and patient education and self-management. Separate chapters are devoted to cognitive changes, psychological problems, and trends in health care utilization among seniors, and all chapters are amplified by current research findings and instructive case studies. As in their recent work.

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Advances in Targeted Cancer Therapy

This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and antibody-based therapeutics. The emphasis is on preclinical development, including target validation, development of biomarkers, strategies for combination approaches, and development of resistance. The particular challenges involved in translating these data to clinical application are discussed.

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Advances in pharmacokinetics and pharmacodynamics

Provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.

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Advances in Network Electrophysiology : Using Multi-Electrode Arrays

This book book is an attempt to review the recent progress in both electronics and computational tools developed to analyze the functional operations of large ensembles of neurons and to provide the readers with a sense of the applications made possible by these technological tools. While considerable progress has been made over the last decades in our understanding of electrophysiological processes at the single channel, single synapse, and single neuron levels, our understanding of electrophysiological

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Advances in Microbiology, Infectious Diseases and Public Health ; Vol.15

Focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues relevant for public health. Original research and review articles present and discuss multidisciplinary findings and developments on various aspects of microbiology, infectious diseases, and their diagnosis, treatment and prevention.

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Advances in Metallodrugs : Preparation and Applications in Medicinal Chemistry

This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering

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Advances in Functional and Reparative Neurosurgery

The fourth official scientific meeting of the Neurorehabilitation and Reconstructive Neurosurgery Committee of the World Federation of Neurosurgical Societies (WFNS) was held in Seoul. This volume is the fourth in a new series of proceedings covering the most important advancements in this field.

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Advances in flavonoids for human health and prevention of diseases

In response to the recent upsurge of interest in the therapeutic potential of medicinal plants, with their promising phenolic compounds, this new book offers an important overview of advances in the applications of flavonoids for health. The book explores the nutritional and pharmacological properties of polyphenols and flavonoids, including their ability to prevent the start and development of diseases and how they aid in the management of several chronic pathological illnesses, including cancer, diabetes, cardiovascular disease, neuro-degenerative illness and aging, pregnancy-induced disorders, and others. Also discussed in depth are the properties, classes, and degrees that formulate a phenolic compound and which subsequently supports the development of drugs/products with health benefits.

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Advances in cognitive neurodynamics ICCN 2007; Proceedings of the International conference on cognitive neurodynamics - 2007

Contains the Proceedings of the 1st International Conference on Cognitive Neurodynamics held in Shanghai, November 17-21, 2007. The participants were treated to an exciting and stimulating conference that left everyone with an enthusiastic vision for the future of the field. The latest important progress was covered by 13 mini-symposia including: Models of Mental Disorders; Cognitive Machines; Dynamics in learning and memory; Central nervous system synchronization; Neuroinformatics; Cognitive Computational Modeling of Human Language Processing; Cognitive Neurodynamics of Attention; Bottom-Up and Top-Down; Brain Networks; From Anatomy to Dynamics; Translational Cognitive Neuroimaging; K-sets; Theory and Applications; Advanced Signal Processing Techniques for Brain Data Analysis; Visual cortex: information processing and dynamics; Dynamics of Firing Patterns and Synchronization in Neuronal Systems.

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Advances in Breast Cancer Management, 2nd ed.

Advances in Breast Cancer Management, Second Edition will highlight many of the important advances that have transformed our understanding of the biology and therapeutics of breast cancer.

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Advances in Alzheimer’s and Parkinson’s Disease : Insights, Progress, and Perspectives

Proceedings of the 7th International Conference on Alzheimer’s Disease and Parkinson’s Disease (ADPD), held March 9-13, 2005 in Sorrento, Italy.The subject matter of the ADPD conferences is unique in that it deals not only with issues related individually to Alzheimer’s disease and Parkinson’s disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, covering topics such as immunology, neuroscience, pharmacology, genetics, molecular biology, biochemistry and the history, epidemiology, clinical phenomenology, diagnosis, imaging, treatment ,and future perspectives of Alzheimer’s and Parkinson’s Diseases.

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Advances and Technical Standards in Neurosurgery ; Vol. 33

This series has already become a classic. In general, one volume is published per year. The advances section presents fields of neurosurgery and related areas in which important recent progress has been made. The technical standards section features detailed descriptions of standard procedures to assist young neurosurgeons in their post-graduate training.

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Advances and Technical Standards in Neurosurgery ; Vol. 30

This series, sponsored by the European Association of Neurosurgical Societies, has already become a classic. In general, one volume is published per year. The Advances section presents fields of neurosurgery and related areas in which important recent progress has been made. The Technical Standards section features detailed descriptions of standard procedures to assist young neurosurgeons in their post-graduate training. The contributions are written by experienced clinicians and are reviewed by all members of the Editorial Board.

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Advances and technical standards in neurosurgery : Vol. 32

This volume of Advances and Technical Standards in Neurosurgery covers some important new developments in functional neurosurgery and endovascular therapy. In the Technical Standards section a variety of topics are considered, including optic pathway gliomas, pineal lesions, cavernous sinus meningiomas, and the eternal problem of minor and repetitive head injury. Endovascular treatment of a variety of lesions is now common practice, and the state of the art in endovascular treatment for acute ischemic stroke is reviewed. An appraisal of the evidence on whether there is a place for microsurgical vascular decompression for essential hypertension raises interesting questions.

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Advanced Techniques in Soil Microbiology

"Advanced Techniques in Soil Microbiology" presents a wide range of biotechnological methods for application in soil microbiology analysis. These include all essential methods involving molecular biology, immunology, microbiology, and structural biology, such as transcriptome analysis, RNAi technology, molecular matchmaking, RAPD, T-RFLP and FT/MS. The techniques and procedures have been selected with the aim of offering practical guides for immediate use in the laboratory. The systems investigated range from individual molecules and cells to entire eukaryotic organisms, with a focus on bacteria, fungi, mycorrhiza, and higher plants. This volume of state-of-the-art, practice oriented methods will be of great use both to the first-timer and to the experienced scientist.

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Advanced soft electronics in biomedical engineering : materials, manufactures, and applications

Presents the latest advances in soft electronics in biomedical engineering and its potential applications in various biomedical fields. Provide comprehensive coverage of how soft electronics are used in diagnostics and monitoring, medical therapy, neural engineering, and wearable and implantable systems. In particular, some emerging research areas such as advanced soft robotics, fiber sensing technologies, and power optimization strategies are explored. In addition, the book highlights international standardization activities in wearable technologies and implantable bioelectronics.

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Advanced Peripheral Nerve Surgery and Minimal Invasive Spinal Surgery

A summary of the most recent and effective techniques for treating difficult functional problems and painful situations using minimally invasive spinal surgery techniques. Including an up-to-date review of the physiopathology of the diseases.

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Advanced chemical biology : chemical dissection and reprogramming of biological systems

Organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections.

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Adrenal Glands : Diagnostic Aspects and Surgical Therapy

Surgery of the Adrenal Glands is a comprehensive medical textbook that includes everything that a surgeon, but for all purposes any physicain or medical student, may want to find on adrenal surgery in a friendly, up to date, evidence based manner. 30 of the most renowned names in the field of adrenal surgery from the US and Europe draw on their experience in exploring diagnosis, indications for surgery, choice of operation and operative techniques, and surgical outcomes for every major adrenal condition. Over 200 exquisite illustrations, ranging from intraoperative photographs, line drawings, diagnostic images, pathology slides, tables and graphs are available to make each case discussed comprehensible and easy to follow. Traditional and novel therapeutic recommendations are introduced and the latest developments in minimal-access operative techniques are discussed and reviewed. Finally, the best approaches in dealing with challenging conditions such as adrenal incidentaloma, subclinical Cushing's syndrom, Congenital Adrenal Hyperplasia, Mineralcorticoid Express Syndrome, Extraadrenal and Malignant Pheochromocytoma are discussed.

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