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This volume critically explores the nature and depth of our contemporary cultural crisis: its lack of traditional orientation and moral understanding. Prime among the issues at stake are the meaning and significance of birth, copulation, suffering, and death, expressed in debates regarding human embryo-experimentation and stem cell research, the character of moral and scientific norms, as well as more fundamentally, the character of an adequate epistemology for coming to appreciate the deep nature of reality and its normative implications.