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Osteoporosis is a major concern all over the world. Therefore, the major aim of our study is to focus on this popular disease and its correlation with aging, a gradual loss of bone mass and results in osteopenia and osteoporosis. Heritable factors account for 60–80% of optimal bone mineralization. Modifiable factors, such as weight-bearing exercise, nutrition, body mass, and hormonal milieu, play an important role in the development of osteopenia and osteoporosis in adulthood. Currently, anti-osteoporosis agents, including estrogen, bisphosphonates, and selective estrogen receptor modulators (SERMs), are the drugs of choice for osteoporosis.