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Virtual colonoscopy, or CT colonography, is a novel and rapidly evolving technique for the detection of tumoral lesions in the colon. It promises to be of great value as a screening tool for both colorectal cancer and its adenomatous precursor. Virtual colonoscopy requires rigorous preparation, colonic distension, and optimization of scanning parameters. Dedicated reading, analysis, and reporting of the data sets are mandatory. With contributions from several leaders in the field, this book addresses all the important issues relating to virtual colonoscopy. There is a particular focus on practical aspects: how to start virtual colonoscopy in your department, the regular preparation, the importance of fecal tagging, how to reduce the preparation, how to obtain optimal colonic distension, and the correct scanning parameters. Imaging characteristics and pitfalls are considered in detail, with an extensive pictorial review of difficult lesions, and the importance of computer-aided diagnosis is discussed.